[ Network menu | Network entry | Help ]

ENTRY	nt06220
Name	Calcium signaling (cancer)
Category	Disease view; Cancer signaling
Display	drug-target relation   disease type

N00026        EGF → EGFR → PLCG → IP3 → Ca2+ → CALM = CAMK N00027            EGFR* → PLCG → IP3 → Ca2+ → CALM = CAMK N00028        PDGF → PDGFR → PLCG → IP3 → Ca2+ → CALM = CAMK N00029            PDGFR* → PLCG → IP3 → Ca2+ → CALM = CAMK N00147        EGF → EGFR → PLCG → IP3 → Ca2+ → CALM = CN → NFAT N00180            K1 → PLCG2 N00172            K15 → PLCG1 N00487    IGH → (LYN,SYK) → (BTK,BLNK) → PLCG2 → IP3 → Ca2+ → CALM = CN → NFAT N00490                P12 = (CALR,CANX) → Ca2+   N00227        TGFA → EGFR → PLCG → IP3 → (Ca2+,DAG) → PKC → ELK1 N00228        TGFA* → EGFR → PLCG → IP3 → (Ca2+,DAG) → PKC → ELK1   N00023        EGF → EGFR → PLCG → IP3 → (Ca2+,DAG) → PKC → RAF → MEK → ERK → CCND1 N00024            EGFR* → PLCG → IP3 → (Ca2+,DAG) → PKC → RAF → MEK → ERK → CCND1 N00025            EML4-ALK → PLCG → IP3 → (Ca2+,DAG) → PKC → RAF → MEK → ERK → CCND1