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ENTRY	nt06274
Name	Thyroid cancer
Category	Disease view; Cancer
Pathway	hsa05216 Thyroid cancer
Disease	H00032 Thyroid cancer
Display	drug-target relation   disease type

N00001    EGF → EGFR → GRB2 → SOS → RAS → RAF → MEK → ERK → CCND1 N00009                TRK* → RAS → RAF → MEK → ERK N10025                Selpercatinib,Pralsetinib ⊥ N00008                RET* → RAS → RAF → MEK → ERK N00012                    (KRAS*,NRAS*) → RAF → MEK → ERK → CCND1 N10007                        (Vemurafenib,Dabrafenib,Encorafenib) ⊥ N10008                            (Trametinib,Cobimetinib,Binimetinib) ⊥ N00013                        BRAF* → MEK → ERK   N00056    WNT → (FZD+LRP5/6) → (DVL+FRAT) ⊣ (GSK3B+AXIN+APC) ⊣ CTNNB1 → TCF/LEF ⇒ (MYC,CCND1) N00061                CDH1* ⌿ CTNNB1 → TCF/LEF ⇒ (MYC,CCND1)   N00115    TP53* ⌿ (CDKN1A,GADD45,BAX.. N00126    PAX8-PPARG ⊣ (RXR+PPARG)