KEGG ORTHOLOGY: K12334

ORTHOLOGY: K12334

Entry

K12334                      KO

Symbol

NPPA

Name

natriuretic peptide A

Pathway

map04022

cGMP-PKG signaling pathway

map04024

cAMP signaling pathway

map04066

HIF-1 signaling pathway

map04270

Vascular smooth muscle contraction

map04714

Thermogenesis

map04921

Oxytocin signaling pathway

map04923

Regulation of lipolysis in adipocytes

map04924

Renin secretion

map04925

Aldosterone synthesis and secretion

map05143

African trypanosomiasis

Disease

H00731

Atrial fibrillation

H02674

Atrial standstill

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    K12334  NPPA; natriuretic peptide A
   04024 cAMP signaling pathway
    K12334  NPPA; natriuretic peptide A
   04022 cGMP-PKG signaling pathway
    K12334  NPPA; natriuretic peptide A
09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K12334  NPPA; natriuretic peptide A
   04921 Oxytocin signaling pathway
    K12334  NPPA; natriuretic peptide A
   04924 Renin secretion
    K12334  NPPA; natriuretic peptide A
   04925 Aldosterone synthesis and secretion
    K12334  NPPA; natriuretic peptide A
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K12334  NPPA; natriuretic peptide A
  09159 Environmental adaptation
   04714 Thermogenesis
    K12334  NPPA; natriuretic peptide A
09160 Human Diseases
  09174 Infectious disease: parasitic
   05143 African trypanosomiasis
    K12334  NPPA; natriuretic peptide A
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K12334  NPPA; natriuretic peptide A
Cytokines and neuropeptides [BR:ko04052]
Neuropeptides
  Neuropeptides (Unclassified)
   K12334  NPPA; natriuretic peptide A

Genes

HSA:	4878(NPPA)

PTR:	736416(NPPA)

PPS:	100976028(NPPA)

GGO:	101133810(NPPA)

PON:	100450656(NPPA)

PPYG:

129007753(NPPA)

NLE:	100597587(NPPA)

HMH:	116812933(NPPA)

SSYN:

129471864(NPPA)

MCC:	714994(NPPA)

MCF:	102116318(NPPA)

MTHB:

126953662

MNI:	105473164(NPPA)

CSAB:

103225596(NPPA)

CATY:

105580855(NPPA)

PANU:

101020837(NPPA)

TGE:	112617020(NPPA)

MLEU:

105551374(NPPA)

RRO:	104657551(NPPA)

RBB:	108539363(NPPA)

TFN:	117093308(NPPA)

PTEH:

111526313(NPPA)

CANG:

105507367(NPPA)

CJC:	100391353(NPPA)

SBQ:	101042923(NPPA)

CIMI:

108286484(NPPA)

ANAN:

105731777(NPPA)

CSYR:

103266203(NPPA)

MMUR:

105882715(NPPA)

LCAT:

123634468(NPPA)

PCOQ:

105824913(NPPA)

OGA:	100961748(NPPA)

MMU:	230899(Nppa)

MCAL:

110293754(Nppa)

MPAH:

110323909(Nppa)

RNO:	24602(Nppa)

MCOC:

116095671(Nppa)

ANU:	117709285(Nppa)

MUN:	110555758(Nppa)

CGE:	100774350(Nppa)

MAUA:

101838783(Nppa)

PROB:

127213212(Nppa)

PLEU:

114709654(Nppa)

MORG:

121441819(Nppa) 121448783

MFOT:

126508247

AAMP:

119817163(Nppa)

NGI:	103747472(Nppa)

HGL:	101718417(Nppa)

CPOC:

100135578(Nppa)

CCAN:

109697786(Nppa)

DORD:

105997441(Nppa)

DSP:	122121425(Nppa)

PLOP:

125355618(Nppa)

NCAR:

124963564

MMMA:

107155409(Nppa)

OCU:	100009087(NPPA)

OPI:	101524664(NPPA)

TUP:	102476150(NPPA)

GVR:	103605175(NPPA)

CFA:	608289(NPPA)

CLUD:

112678119(NPPA)

VVP:	112929727(NPPA)

VLG:	121498195(NPPA)

NPO:	129513571(NPPA)

AML:	100469861(NPPA)

UMR:	103666859(NPPA)

UAH:	113270670(NPPA)

UAR:	123779108(NPPA)

ELK:

111154752

LLV:

125098242

MPUF:

101693245(NPPA)

MNP:	132001223(NPPA)

MLK:	131810182(NPPA)

NVS:	122899071(NPPA)

ORO:	101368657(NPPA)

EJU:	114213306(NPPA)

ZCA:	113935998(NPPA)

MLX:	118020338(NPPA)

NSU:	110574671(NPPA)

LWW:	102743916(NPPA)

FCA:	101100575(NPPA)

PYU:	121018096(NPPA)

PCOO:

112861584(NPPA)

PBG:	122479547(NPPA)

PVIV:

125171797(NPPA)

LRUF:

124514414

PTG:	102969166(NPPA)

PPAD:

109274120(NPPA)

PUC:

125913108

AJU:

106971865

HHV:	120233651(NPPA)

BTA:	281355(NPPA)

BOM:	102287668(NPPA)

BIU:	109570145(NPPA)

BBUB:

123465754(NPPA)

BBIS:

104995833(NPPA)

CHX:	102181974(NPPA)

OAS:	100294648(NPPA)

BTAX:

128061259(NPPA)

ODA:	120880230(NPPA)

CCAD:

122452300(NPPA)

MBEZ:

129551090(NPPA)

SSC:	397496(NPPA)

CFR:	102505165(NPPA)

CBAI:

105070962(NPPA)

CDK:	105107036(NPPA)

VPC:	102533440(NPPA)

BACU:

102997559(NPPA)

BMUS:

118902888(NPPA)

LVE:	103080153(NPPA)

OOR:	101288321(NPPA)

DLE:	111187199(NPPA)

PCAD:

102985624(NPPA)

PSIU:

116760402(NPPA)

NASI:

112402761(NPPA)

ECB:	100034201(NPPA)

EPZ:	103552182(NPPA)

EAI:	106836709(NPPA)

MYB:	102245841(NPPA)

MYD:	102763515(NPPA)

MMYO:

118676554(NPPA)

MLF:	102439379 102441292

MDT:	132229799(NPPA)

PKL:	118732065(NPPA)

EFUS:

103295419(NPPA)

MNA:	107531532(NPPA)

DRO:	112299659(NPPA)

SHON:

118986392(NPPA)

AJM:	119064118(NPPA)

PDIC:

114498080(NPPA)

PHAS:

123832118(NPPA)

MMF:	118627116(NPPA)

PPAM:

129075595(NPPA)

HAI:	109381245(NPPA)

RFQ:	117027714(NPPA)

PALE:

102881128(NPPA)

PGIG:

120585723(NPPA)

PVP:	105294426(NPPA)

MJV:	108385718(NPPA)

TOD:	119236026(NPPA)

SARA:

101556790(NPPA)

SETR:

126011620(NPPA)

LAV:	100660875(NPPA)

TMU:

101359460

ETF:	101664239(NPPA)

DNM:	101427056(NPPA)

MDO:	100018089(NPPA)

GAS:	123240966(NPPA)

SHR:	100928886(NPPA)

AFZ:

127558173

PCW:	110197963(NPPA)

TVP:	118840044(NPPA)

OAA:	100086091(NPPA)

GGA:	395765(NPPA)

PCOC:

116242626

MGP:	100545392(NPPA) 104914182

CJO:	107323378 107323379

TPAI:

128084924(NPPA)

LMUT:

NMEL:

APLA:

ACYG:

CATA:

118253388(NPPA)

AFUL:

116497646

TGU:	100217781(NPPA)

LSR:	110479723(NPPA)

SCAN:

103820846

PMOA:

120496783(NPPA)

OTC:	121343934(NPPA)

PRUF:

121358380

GFR:	102032903(NPPA)

FAB:	101816669(NPPA)

OMA:

130261724

PHI:

102110039

PMAJ:

107213729(NPPA)

CCAE:

111938715

CCW:

104693244

CBRC:

103616121(NPPA)

ETL:	114056867(NPPA)

ZAB:

102071715

ZLE:	135456798(NPPA)

ACHL:

103799159

SVG:

106856448

MMEA:

130583476

HRT:	120762442(NPPA)

SATI:

136370770(NPPA)

FPG:	101920851(NPPA)

FCH:

CCRI:

NNT:

SHAB:

ACUN:

113487811(NPPA)

TALA:

ACHC:

HALD:

HLE:

AGEN:

GCL:

CSTI:

LDI:

MNB:

DPUB:

AVIT:

BRHI:

EGZ:

NNI:

PCRI:

PCAO:

PADL:

103917988(NPPA)

AFOR:

103907442(NPPA)

FGA:

104078241

GSTE:

104252905

CLV:	102089713(BNP)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

TEO:

BREG:

OHA:

ACAR:

CPEA:

CVF:	104290446(NPPA)

RTD:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:	102367833 102374118

AMJ:	102572997(NPPB) 102576972

CPOO:

109314264(NPPA)

GGN:	109293664(NPPA)

PSS:	102447765 102448016

CMY:	102934895 102945470

CCAY:

125624356 125624481

DCC:	119845051 119845228

CPIC:

101945004 101945284

TST:	117867915 117868089

CABI:

116821908 116821967

MRV:	120387766 120388036

ASAO:

132764990 132764993

PVT:	110073098 110073141

SUND:

121936152 121936154

PBI:	103051068 103051307 103058660

PMUR:

CTIG:

PGUT:

APRI:

PTEX:

113450044 113450065 113450066

NSS:	113428532 113428544

VKO:	123031064 123031065 123031087

PMUA:

114602800 114602801 114603323

PRAF:

128419875 128419880

ZVI:	118086841 118086842 118087774

HCG:	128338374 128338375

STOW:

125445891

EMC:

129344849

XLA:	108697555(nppb.S) 394320(nppa.L) 779298(nppa.S)

XTR:	100495594(nppa)

NPR:	108799421 108799429

RTEM:

120915516 120915517

BBUF:

120999579

BGAR:

122926821(NPPA)

MUO:	115456540(NPPA)

GSH:

117349378

DRE:	321442(nppa)

SRX:	107710773 107748994

SANH:

107687143 107691053

SGH:	107595801 107602452

CCAR:

109094492 109094493 109094663

CAUA:

113097254 113107830

CGIB:

127963078 128018209

PTET:

122350069(nppa)

LROH:

127169449(nppa)

OMC:	131545757(nppa)

PPRM:

120489969(nppa)

RKG:	130081822(nppa)

MAMB:

125280034(nppa)

CIDE:

127518048

CERY:

137026624(nppa)

MASI:

127414481 127424758

TROS:

130549607(nppa)

TDW:	130406965(nppa)

MANU:

129414961(nppa)

IPU:	108265034(nppb) 108265035(nppa)

IFU:	128607569(nppa)

PHYP:

113533456

SMEO:

124400047(nppa)

TFD:	113656286(nppa)

TRN:	134317786(nppa)

AMEX:

103032860(nppa)

CMAO:

118813599(nppa)

EEE:

113578185

CHAR:

105904258 122132853(nppa)

TRU:	445903(nppa) 446068(nppb)

TFS:	130530378(nppa)

TNG:	GSTEN00004914G001

LCO:

104930388

NCC:

104961889

TBEN:

117481472(nppa)

CGOB:

115011226(nppb)

PGEO:

117449859(nppa)

GACU:

117559268

EMAC:

134867567(nppa)

ELY:	117257997(nppa)

EFO:	125892061(nppa)

PLEP:

121947155(nppa)

SLUC:

116039183(nppa)

ECRA:

117947704(nppa)

ESP:	116692173(nppa)

PFLV:

114559183(nppa)

GAT:	120829243(nppa)

PPUG:

119223726(nppa)

AFB:	129099407(nppa)

CLUM:

117733522(nppa)

PSWI:

130199647(nppa)

MSAM:

119904993(nppa)

SCHU:

122883720(nppa)

CUD:	121517079(nppa)

ALAT:

119023444(nppa)

ASTR:

137611544(nppa)

ONL:

100705260

OAU:	116326141(nppa)

XHE:	116722600(nppa)

PFOR:

103153472(nppa)

PLAI:

106953334(nppa)

PMEI:

106925028(nppa)

GAF:	122831618(nppa)

PPRL:

129377133(nppa)

CVG:	107090718(nppa)

CTUL:

119799466(nppa)

GMU:	124867914(nppa)

KMR:	108248160(nppa)

NWH:	119416860(nppa)

AOCE:

111566107

CSEM:

107989131

POV:

109642868

SSEN:

122777607(nppa)

HHIP:

117764740

HSP:	118110516(nppa)

PPLT:

128442309(nppa)

SMAU:

118316887(nppa)

LCF:	108880353 108900482

SDU:

111233811

SLAL:

111658869(nppa)

XGL:	120803280(nppa)

HCQ:

109528291

SSCV:

125988240

SBIA:

133495064(nppa)

PEE:	133414061(nppa)

PTAO:

133486682(nppa)

BPEC:

110165628

MALB:

109975072(nppa)

BSPL:

114858354(nppa)

SJO:	128357033(nppa)

SASA:

100136387 106567366 106572129 106572130

STRU:

115166010 115168940 115168942

OTW:	112215982 112221384 112233906

OMY:	100135815(anp) 100135816(vnp) 110533017

OGO:	124021865 124045185 124045187

ONE:	115102607 115102608 115132803

OKI:	109869470 109869588 109908537

OKE:	118359505 118360207 118361066

SALP:

111976323 111976975 112068456 112068457

SNH:	120058685 120060598 120060600

CCLU:

121537483 121545941(nppa) 121546768

ELS:	105013773 105013774

SFM:

108924875

PKI:	111859115(nppa)

AANG:

118207604 118208420

LOC:	102687191(nppa)

PSPA:

121328521 121328833 121329186 121329307

ARUT:

117425089 117425135 117426082 117426083

» show all

Reference

PMID:6203042

Authors

Oikawa S, Imai M, Ueno A, Tanaka S, Noguchi T, Nakazato H, Kangawa K, Fukuda A, Matsuo H

Title

Cloning and sequence analysis of cDNA encoding a precursor for human atrial natriuretic polypeptide.

Journal

Nature 309:724-6 (1984)
DOI:10.1038/309724a0

Sequence

[hsa:4878]

Reference

PMID:21296556

Authors

Nishikimi T, Kuwahara K, Nakao K

Title

Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides.

Journal

J Cardiol 57:131-40 (2011)
DOI:10.1016/j.jjcc.2011.01.002

LinkDB

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