KEGG ORTHOLOGY: K19873

ORTHOLOGY: K19873

Entry

K19873                      KO

Symbol

FKRP

Name

fukutin-related protein [EC:2.7.8.-]

Pathway

map00515

Mannose type O-glycan biosynthesis

map01100

Metabolic pathways

Module

M00872

O-glycan biosynthesis, mannose type (core M3)

Reaction

R12295

Disease

H00120

Muscular dystrophy-dystroglycanopathy type A

H00593

Limb-girdle muscular dystrophy

H01959

Muscular dystrophy-dystroglycanopathy type C

H01960

Muscular dystrophy-dystroglycanopathy type B

H01961

Congenital muscular dystrophy type 1C

H02307

Muscular dystrophy-dystroglycanopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00515 Mannose type O-glycan biosynthesis
    K19873  FKRP; fukutin-related protein
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K19873  FKRP; fukutin-related protein
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K19873  FKRP; fukutin-related protein
Glycosyltransferases [BR:ko01003]
Glycan extension
  O-Glycan
   K19873  FKRP; fukutin-related protein
Membrane trafficking [BR:ko04131]
Endoplasmic reticulum (ER) - Golgi transport
  Others
   Others
    K19873  FKRP; fukutin-related protein

Genes

HSA:	79147(FKRP)

PTR:	746394(FKRP)

PPS:	100985780(FKRP)

GGO:	101150963(FKRP)

PON:	100939505(FKRP)

PPYG:

129021182(FKRP)

NLE:	101176622(FKRP)

HMH:	116478303(FKRP)

SSYN:

129459362(FKRP)

MCC:	716804(FKRP)

MCF:	102145392(FKRP)

MTHB:

126943459

MNI:	105478591(FKRP)

CSAB:

103234922(FKRP)

CATY:

105595190(FKRP)

PANU:

101014394(FKRP)

TGE:	112611870(FKRP)

RRO:	104673400(FKRP)

RBB:	108531065(FKRP)

TFN:	117091454(FKRP)

PTEH:

111520146(FKRP)

CANG:

105526959(FKRP)

CJC:	100385568(FKRP)

SBQ:	101031020(FKRP)

CIMI:

108283830

ANAN:

105713085(FKRP)

MMUR:

105869575(FKRP)

LCAT:

123623913

PCOQ:

105817643(FKRP)

OGA:	100942757(FKRP)

MMU:	243853(Fkrp)

MCAL:

110297288(Fkrp)

RNO:	308390(Fkrp)

MCOC:

116101700(Fkrp)

ANU:	117700431(Fkrp)

MUN:	110552649(Fkrp)

CGE:

113837384

MAUA:

101824132

PROB:

127238585(Fkrp)

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103724683(Fkrp)

HGL:	101720645(Fkrp)

CPOC:

100717803(Fkrp)

CCAN:

109691207(Fkrp)

DORD:

105997981(Fkrp)

DSP:

PLOP:

NCAR:

MMMA:

OCU:

OPI:

TUP:	102495781(FKRP)

GVR:	103592992(FKRP)

CFA:	484426(FKRP)

CLUD:

112645259

VVP:	112931236(FKRP)

VLG:

121484029

NPO:	129500506(FKRP)

AML:	105239258(FKRP)

UMR:

121103510

UAH:	113243391(FKRP)

UAR:

123778747

ELK:

111160607

LLV:

125089227

MPUF:

101672499(FKRP)

MNP:	132006081(FKRP)

MLK:	131818459(FKRP)

NVS:

122911913

ORO:	101369912(FKRP)

EJU:	114197113(FKRP)

ZCA:

113935526

MLX:	117998182(FKRP)

NSU:

110572922

LWW:	102737527(FKRP)

FCA:	101099604(FKRP)

PYU:

121018876

PBG:

122494929

PVIV:

125152797(FKRP)

LRUF:

124510991

PPAD:

109253188(FKRP)

PUC:

125915325

AJU:

106973633

HHV:

120241054

BTA:	539701(FKRP)

BOM:	102285743(FKRP)

BIU:	109572836(FKRP)

BBUB:

102405213

BBIS:

104997794(FKRP)

CHX:	102170263(FKRP)

OAS:	101117098(FKRP)

BTAX:

128063897(FKRP)

ODA:

120872243

CCAD:

122420339

MBEZ:

129546631(FKRP)

SSC:	100516858(FKRP)

CFR:	102516315(FKRP)

CBAI:

105062729(FKRP)

CDK:

105104044

VPC:	102536672(FKRP)

BACU:

103003058(FKRP)

BMUS:

118884528

LVE:	103090150(FKRP)

OOR:	101278326(FKRP)

DLE:	111180706(FKRP)

PCAD:

102975408(FKRP)

PSIU:

116743902(FKRP)

NASI:

112415545(FKRP)

ECB:	102148152(FKRP)

EPZ:	103567871(FKRP)

EAI:

123281125

MMYO:

118652756

MLF:	102428268(FKRP)

MDT:	132216681(FKRP)

PKL:

118706753

EFUS:

103297691(FKRP)

MNA:	107536720(FKRP)

DRO:	112312945(FKRP)

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

129082878(FKRP)

HAI:	109372216(FKRP)

RFQ:	117035189(FKRP)

PALE:

102892092(FKRP)

PGIG:

120617893

PVP:	105297319(FKRP)

RAY:	107516005(FKRP)

MJV:

108406138

TOD:	119249474(FKRP)

SARA:

101555533(FKRP)

SETR:

126028223(FKRP)

LAV:	100659032(FKRP)

TMU:

101346759

ETF:

101657129

DNM:	101416562(FKRP)

MDO:	100016806(FKRP)

GAS:

123242970

AFZ:

127556265

PCW:	110202395(FKRP)

TVP:

118837628

OAA:

100083058

PCOC:

116241214(FKRP)

MGP:	100539231(FKRP)

CJO:	107307664(FKRP)

NMEL:

110391679(FKRP)

ACYG:

125181445(FKRP)

TGU:	115492891(FKRP)

LSR:	110481241(FKRP)

PMOA:

120511905

OTC:

121335571

PRUF:

121351792

PHI:	102112214(FKRP)

CCAE:

111942658(FKRP)

ETL:	114073076(FKRP)

ZLE:	135441336 135441954

SVG:	106864387(FKRP)

MMEA:

130587555(FKRP)

FPG:	101924545(FKRP)

FCH:	102055406(FKRP)

SHAB:

115603245(FKRP)

TALA:

116964733

ACHC:

115338294

HLE:	104831567(FKRP)

AGEN:

126037088

GCL:

127028681

CSTI:

104552635(FKRP)

NNI:	104020658(FKRP)

CUCA:

104054241(FKRP)

RTD:	128901622(FKRP)

ASN:	102374089(FKRP)

AMJ:	102557681(FKRP)

PSS:	102456705(FKRP)

CMY:

CCAY:

DCC:

CPIC:

TST:	117888542(FKRP)

CABI:

116835273(FKRP)

MRV:

120388240

ACS:	100563173(fkrp)

ASAO:

132781761(FKRP)

PVT:	110075682(FKRP)

SUND:

121915895

PBI:	103051503(FKRP)

PMUR:

107291938(FKRP)

CTIG:

120299832

TSR:	106549687(FKRP)

PGUT:

117677769(FKRP)

APRI:

131204316(FKRP)

PTEX:

113446054(FKRP)

NSS:	113425798(FKRP)

VKO:

123026190

PMUA:

114603278(FKRP)

PRAF:

128420291(FKRP)

ZVI:	118086588(FKRP)

HCG:	128332961(FKRP)

GJA:	107121228(FKRP)

STOW:

125434897

EMC:	129343046(FKRP)

XLA:	108698503(fkrp.L)

XTR:	100145309(fkrp)

RTEM:

120921959

BBUF:

121009294

BGAR:

122922439

MUO:	115479539(FKRP)

GSH:	117364575(FKRP)

DRE:	571426(fkrp)

SRX:	107728156 107752280

SANH:

107699175 107699218

SGH:	107566082 107592673

CCAR:

109103823

CAUA:

113115268(fkrp)

CGIB:

127972445

PTET:

122358522

LROH:

127177069(fkrp)

OMC:	131554166(fkrp)

PPRM:

120479026

RKG:	130095725(fkrp)

MAMB:

125248119

CIDE:

127496032

CERY:

137005055(fkrp)

MASI:

127422115 127429558

TROS:

130564768(fkrp)

TDW:	130428449(fkrp)

MANU:

129437717(fkrp)

IPU:

108277811

IFU:	128621837(fkrp)

PHYP:

113544649(fkrp)

SMEO:

124394622

TFD:

113639212

TVC:	132858484(fkrp)

TRN:	134334466(fkrp)

AMEX:

103033897

CMAO:

118798092

EEE:	113579447(fkrp)

CHAR:

105901531

TRU:	101072335(fkrp)

TFS:	130535504(fkrp)

TNG:	GSTEN00014836G001

LCO:	104918000(fkrp)

NCC:	104956814(fkrp)

TBEN:

117470510(fkrp)

CGOB:

115017287(fkrp)

PGEO:

117457088(fkrp)

GACU:

117552176(fkrp)

EMAC:

134879730(fkrp)

ELY:	117259427(fkrp)

EFO:

125888753

PLEP:

121943563

SLUC:

116047741

ECRA:

117938985(fkrp)

ESP:	116687021(fkrp)

PFLV:

114552599(fkrp)

GAT:

120817884

PPUG:

119214109

AFB:	129103394(fkrp)

CLUM:

117741590(fkrp)

PSWI:

130211140(fkrp)

MSAM:

SCHU:

CUD:

ALAT:

ASTR:

137596750(fkrp)

MZE:	101473184(fkrp)

ONL:	100691656(fkrp)

OAU:

116314730

OLA:	101164830(fkrp)

OML:

112149986

CSAI:

133442366(fkrp)

XMA:	102220799(fkrp)

XCO:	114133658(fkrp)

XHE:	116708234(fkrp)

PRET:

103474615(fkrp)

PFOR:

103136264(fkrp)

PLAI:

106953842(fkrp)

PMEI:

106934075(fkrp)

GAF:

122833235

PPRL:

129358687(fkrp)

CVG:	107086351(fkrp)

CTUL:

119792127

GMU:

124883944

NFU:	107380306(fkrp)

KMR:

108243504

ALIM:

106515418(fkrp)

NWH:

119411244

AOCE:

111578697(fkrp)

MCEP:

125013935

CSEM:

103378096(fkrp)

POV:	109629986(fkrp)

SSEN:

122773525

HHIP:

117772520(fkrp)

HSP:

118106418

PPLT:

128440169(fkrp)

SMAU:

118299140

LCF:

108900824

SDU:	111238891(fkrp)

SLAL:

111655976(fkrp) 111660280

XGL:

120791666

HCQ:	109526345(fkrp)

SSCV:

125972417

SBIA:

133504360(fkrp)

PEE:	133404741(fkrp)

PTAO:

133482566(fkrp)

BPEC:

110154138(fkrp)

MALB:

109973528(fkrp)

BSPL:

114867701(fkrp)

SJO:	128360573(fkrp)

SASA:

106612391(fkrp)

STRU:

115163002 115205961

OTW:	112265090 112266683

OMY:

110507438

OGO:	123993051 124004846

ONE:	115137072 115141443

OKI:	109881121 109905432

OKE:	118385876 118397144(fkrp)

SALP:

111949717 111960617

SNH:	120018396 120028549

CCLU:

121562124 121567391

ELS:	105012202(fkrp)

SFM:	108932181(fkrp)

PKI:	111844886(fkrp)

AANG:

118209663(fkrp)

LOC:	102690461(fkrp)

PSPA:

121304954

ARUT:

117396672(fkrp)

PSEX:

120538658

LCM:	102354608(FKRP)

RTP:

109934048

CPLA:

122542812

HOC:	132836771(fkrp)

LERI:

129714160(fkrp)

PMRN:

116947928(FKRP)

LRJ:	133341209 133341229

BFO:

BBEL:

AJC:

SKO:

DME:	Dmel_CG15651(CG15651)

DER:

6547647

DSE:

6615278

DSI:	Dsimw501_GD25239(Dsim_GD25239)

DYA:	Dyak_GE13757

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18554

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:	101888188 131801670

SCAC:

LCQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ000997

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:	105281844 105282118 113562259

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

SOY:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

OTU:	111416224 111416784

BMOR:

101735578

BMAN:

114241820

MSEX:

115443225

DPL:	KGM_214666

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

CCRN:

BTAB:

DCI:	103504964 103520532

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM592890

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

HAZT:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:	129222106 129233684

SDM:

118184502

LPOL:

106457670

PMEO:

129594191

LGI:	LOTGIDRAFT_127610

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

116294890 116303658 116306763 116308737

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_14979

MBR:	MONBRDRAFT_27401

SRE:	PTSG_06808

» show all

Reference

PMID:21886772

Authors

Alhamidi M, Kjeldsen Buvang E, Fagerheim T, Brox V, Lindal S, Van Ghelue M, Nilssen O

Title

Fukutin-related protein resides in the Golgi cisternae of skeletal muscle fibres and forms disulfide-linked homodimers via an N-terminal interaction.

Journal

PLoS One 6:e22968 (2011)
DOI:10.1371/journal.pone.0022968

Sequence

[hsa:79147]

LinkDB

DBGET integrated database retrieval system