Entry
Name
Sphingolipid metabolism
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
Ortholog table
Module
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:ec00600 ]
Other DBs
Enzyme
Compound
C01120 Sphinganine 1-phosphate
C03405 Lactosylceramide sulfate
C03640 Sphingosyl-phosphocholine
C04737 alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884 N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911 D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681 Ceramide 2-aminoethylphosphonate
C06062 Ceramide phosphoethanolamine
C06124 Sphingosine 1-phosphate
C06127 Digalactosylceramide sulfate
C22467 Gangliotriaosylceramide-II3 sulfate
Reference
Authors
Merrill AH Jr.
Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
Journal
Reference
Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
Journal
Reference
Authors
Hannun YA, Luberto C, Argraves KM.
Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
Journal
Reference
Authors
Merrill AH Jr, Wang E.
Title
Enzymes of ceramide biosynthesis.
Journal
Reference
Authors
Hirschberg K, Rodger J, Futerman AH.
Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
Journal
Reference
Authors
Dickson RC, Lester RL.
Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
Journal
Related pathway
ec00260 Glycine, serine and threonine metabolism
ec00601 Glycosphingolipid biosynthesis - lacto and neolacto series
ec00603 Glycosphingolipid biosynthesis - globo and isoglobo series
ec00604 Glycosphingolipid biosynthesis - ganglio series
KO pathway
LinkDB
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