KEGG   PATHWAY: gacu04070
Entry
gacu04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Gymnodraco acuticeps
Class
Environmental Information Processing; Signal transduction
Pathway map
gacu04070  Phosphatidylinositol signaling system
gacu04070

Organism
Gymnodraco acuticeps [GN:gacu]
Gene
117532434  [KO:K00901] [EC:2.7.1.107]
117532612  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
117532616  [KO:K00889] [EC:2.7.1.68]
117532908  [KO:K00901] [EC:2.7.1.107]
117533629  ppip5k1a; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
117534187  [KO:K00920] [EC:2.7.1.149]
117534191  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
117534202  dgkab; diacylglycerol kinase, alpha b isoform X1 [KO:K00901] [EC:2.7.1.107]
117534275  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
117534574  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
117534905  inppl1a; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
117535004  [KO:K02649]
117535356  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
117535670  synj1; LOW QUALITY PROTEIN: synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
117535850  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
117536300  [KO:K04960]
117536702  [KO:K00889] [EC:2.7.1.68]
117537187  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
117537278  pi4k2b; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
117537407  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
117537622  inppl1b; LOW QUALITY PROTEIN: inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
117538102  [KO:K00901] [EC:2.7.1.107]
117538508  mtmr2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
117538551  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
117538618  pip4p1a; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A isoform X1 [KO:K13084] [EC:3.1.3.78]
117538957  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
117538959  [KO:K05861] [EC:3.1.4.11]
117539107  [KO:K21797] [EC:3.1.3.-]
117539131  [KO:K21797] [EC:3.1.3.-]
117539199  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
117539291  [KO:K01109] [EC:3.1.3.66]
117539349  [KO:K00901] [EC:2.7.1.107]
117539693  calm1a; calmodulin-1a [KO:K02183]
117539825  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
117540539  [KO:K01109] [EC:3.1.3.66]
117540673  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
117541517  si:dkey-172j4.3; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
117541887  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
117542242  ip6k1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
117542274  [KO:K02649]
117542378  [KO:K00922] [EC:2.7.1.153]
117542579  [KO:K00889] [EC:2.7.1.68]
117543213  prkcg; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
117543274  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
117543466  ocrl; LOW QUALITY PROTEIN: inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
117543539  si:ch73-22a13.3; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
117543606  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
117543685  [KO:K07756] [EC:2.7.4.21]
117543700  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
117544562  inpp4aa; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
117544647  [KO:K01092] [EC:3.1.3.25]
117544804  [KO:K01092] [EC:3.1.3.25]
117544931  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
117545182  plcd3b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
117545410  [KO:K05858] [EC:3.1.4.11]
117545508  [KO:K00922] [EC:2.7.1.153]
117545568  [KO:K02649]
117545674  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
117546175  [KO:K00901] [EC:2.7.1.107]
117546482  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
117546606  [KO:K05857] [EC:3.1.4.11]
117548366  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A isoform X1 [KO:K05857] [EC:3.1.4.11]
117548389  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
117548467  [KO:K00901] [EC:2.7.1.107]
117548584  bpnt2; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
117548684  si:ch73-374l24.1; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
117549120  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
117549326  calml4a; calmodulin-like protein 4a isoform X1 [KO:K02183]
117549478  [KO:K05857] [EC:3.1.4.11]
117549938  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
117549998  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
117550030  itpk1b; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
117550444  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
117550693  mtmr7a; myotubularin-related protein 7a isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
117550918  [KO:K01106] [EC:3.1.3.56]
117551047  [KO:K04958]
117551115  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
117551299  pi4kaa; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
117551606  mtmr7b; myotubularin-related protein 7b [KO:K18083] [EC:3.1.3.64 3.1.3.95]
117551852  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
117551971  [KO:K19662] [EC:2.7.11.13]
117552074  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
117552177  calm3a; calmodulin 3a (phosphorylase kinase, delta) [KO:K02183]
117552390  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
117552425  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
117552612  [KO:K04960]
117553131  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
117553219  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
117553312  [KO:K00889] [EC:2.7.1.68]
117553935  [KO:K00889] [EC:2.7.1.68]
117554106  sacm1lb; phosphatidylinositide phosphatase SAC1-B [KO:K21797] [EC:3.1.3.-]
117554181  [KO:K05858] [EC:3.1.4.11]
117554187  [KO:K02183]
117554205  [KO:K05858] [EC:3.1.4.11]
117554849  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
117555130  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
117556101  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
117556109  [KO:K19662] [EC:2.7.11.13]
117556566  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
117556571  mtm1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
117556585  [KO:K05857] [EC:3.1.4.11]
117556780  [KO:K01092] [EC:3.1.3.25]
117556781  [KO:K01092] [EC:3.1.3.25]
117557046  pi4kb; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
117557274  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
117557389  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
117557463  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
117559043  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
117559234  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
117560318  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
117560374  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b isoform X1 [KO:K00888] [EC:2.7.1.67]
117560594  [KO:K01116] [EC:3.1.4.11]
117560597  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
117560847  ptena; phosphatase and tensin homolog A isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
117561002  inpp5l; LOW QUALITY PROTEIN: inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
117561441  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
117561627  [KO:K13084] [EC:3.1.3.78]
117561679  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
117561994  prkcaa; protein kinase C, alpha, a [KO:K02677] [EC:2.7.11.13]
117562516  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
117562520  [KO:K00920] [EC:2.7.1.149]
117563130  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
gacu04020  Calcium signaling pathway
gacu04144  Endocytosis
gacu04510  Focal adhesion
KO pathway
ko04070   

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