KEGG   PATHWAY: gga04070
Entry
gga04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Gallus gallus (chicken)
Class
Environmental Information Processing; Signal transduction
Pathway map
gga04070  Phosphatidylinositol signaling system
gga04070

Organism
Gallus gallus (chicken) [GN:gga]
Gene
416767  PI4KA; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
100859723  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
422807  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
425291  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
420700  SACM1L; phosphatidylinositide phosphatase SAC1 isoform 1 [KO:K21797] [EC:3.1.3.-]
423932  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X2 [KO:K21798] [EC:3.1.3.-]
427243  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
420072  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [KO:K00889] [EC:2.7.1.68]
429983  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
419609  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
422136  OCRL; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
417135  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
418498  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
421656  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
424971  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
419444  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
424826  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
429096  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2 [KO:K02649]
771142  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
427171  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
423675  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
424745  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
428692  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
422454  INPP4B; type II inositol 3,4-bisphosphate 4-phosphatase isoform X4 [KO:K01109] [EC:3.1.3.66]
418690  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
424114  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
422388  MTM1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
418992  MTMR2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
422387  MTMR1; myotubularin-related protein 1 isoform X2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
417015  MTMR3; myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
417472  MTMR4; myotubularin-related protein 4 isoform X2 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
418938  MTMR6; myotubularin-related protein 6 isoform X2 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
422312  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
422731  MTMR7; myotubularin-related protein 7 isoform X2 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
416048  MTMR14; myotubularin-related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
420504  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
419999  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
420221  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
100857877  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2 [KO:K00914] [EC:2.7.1.137]
418181  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
423070  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
419822  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
423014  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X2 [KO:K05858] [EC:3.1.4.11]
416730  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [KO:K05858] [EC:3.1.4.11]
427687  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
420416  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X4 [KO:K05857] [EC:3.1.4.11]
424214  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X3 [KO:K05857] [EC:3.1.4.11]
428279  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X5 [KO:K05857] [EC:3.1.4.11]
425224  PLCE1; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
419175  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
776273  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2 [KO:K01116] [EC:3.1.4.11]
415805  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
418182  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
101751177  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
416743  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
395694  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
423973  INPP5A; type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01106] [EC:3.1.3.56]
423421  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
415951  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
419908  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
416010  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
100857294  IP6K1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
427276  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
415587  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
107049248  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
420199  IMPA1; inositol monophosphatase 1 isoform X1 [KO:K01092] [EC:3.1.3.25]
421032  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
421132  IMPAD1; inositol monophosphatase 3 isoform X2 [KO:K15759] [EC:3.1.3.7]
427381  DGKQ; LOW QUALITY PROTEIN: diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
772367  DGKB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
770911  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
769506  DGKH; diacylglycerol kinase eta isoform X2 [KO:K00901] [EC:2.7.1.107]
423197  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
418124  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
422129  DGKK; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
424839  DGKG; diacylglycerol kinase gamma isoform X2 [KO:K00901] [EC:2.7.1.107]
424747  DGKD; diacylglycerol kinase delta isoform X2 [KO:K00901] [EC:2.7.1.107]
101748037  DGKA; LOW QUALITY PROTEIN: diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
422611  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
419517  CDS2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
395412  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
418212  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
419910  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
417430  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
416567  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
396523  CALM1; neo-calmodulin [KO:K02183]
416692  CALML3; calmodulin, striated muscle [KO:K02183]
395855  CALM2; calmodulin [KO:K02183]
427515  CALML4; calmodulin-like protein 4 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
gga04020  Calcium signaling pathway
gga04144  Endocytosis
gga04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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