KEGG   PATHWAY: mthb00600
Entry
mthb00600                   Pathway                                
Name
Sphingolipid metabolism - Macaca thibetana thibetana (Pere David's macaque)
Class
Metabolism; Lipid metabolism
Pathway map
mthb00600  Sphingolipid metabolism
mthb00600

Module
mthb_M00066  Lactosylceramide biosynthesis [PATH:mthb00600]
mthb_M00067  Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:mthb00600]
mthb_M00094  Ceramide biosynthesis [PATH:mthb00600]
mthb_M00099  Sphingosine biosynthesis [PATH:mthb00600]
mthb_M00100  Sphingosine degradation [PATH:mthb00600]
Other DBs
GO: 0006665
Organism
Macaca thibetana thibetana (Pere David's macaque) [GN:mthb]
Gene
126929434  [KO:K01134] [EC:3.1.6.8]
126929864  [KO:K00654] [EC:2.3.1.50]
126930376  [KO:K00725] [EC:2.4.1.92]
126931016  [KO:K23727]
126932012  [KO:K23727]
126932180  [KO:K24621]
126932573  [KO:K12357] [EC:3.2.1.18]
126932743  [KO:K01080] [EC:3.1.3.4]
126932788  [KO:K12357] [EC:3.2.1.18]
126932847  [KO:K04717] [EC:3.1.3.-]
126933930  [KO:K01201] [EC:3.2.1.45]
126935049  [KO:K12350] [EC:3.1.4.12]
126935050  [KO:K12357] [EC:3.2.1.18]
126936344  [KO:K04711] [EC:3.5.1.-]
126936821  [KO:K00720] [EC:2.4.1.80]
126937401  [KO:K04712] [EC:1.14.19.17 1.14.18.5]
126937696  [KO:K01441] [EC:3.5.1.23]
126938015  [KO:K00654] [EC:2.3.1.50]
126938032  [KO:K17108] [EC:3.2.1.45]
126939236  [KO:K04718] [EC:2.7.1.91]
126939286  [KO:K12354] [EC:3.1.4.12]
126941475  [KO:K04708] [EC:1.1.1.102]
126941555  [KO:K07553] [EC:2.4.1.274]
126942298  [KO:K04710] [EC:2.3.1.299]
126942676  [KO:K24621]
126942782  [KO:K01441] [EC:3.5.1.23]
126942972  [KO:K01080] [EC:3.1.3.4]
126943556  [KO:K04718] [EC:2.7.1.91]
126944061  [KO:K12352] [EC:3.1.4.12]
126946007  [KO:K01189] [EC:3.2.1.22]
126947919  [KO:K12353] [EC:3.1.4.12]
126948055  [KO:K12309] [EC:3.2.1.23]
126953207  [KO:K01186] [EC:3.2.1.18]
126953633  [KO:K12351] [EC:3.1.4.12]
126954282  [KO:K04628] [EC:2.4.1.47]
126954936  [KO:K04714] [EC:2.7.8.27 3.1.4.62]
126955511  [KO:K12382]
126956513  [KO:K12373] [EC:3.2.1.52]
126956615  [KO:K12383]
126957166  [KO:K01080] [EC:3.1.3.4]
126958148  [KO:K12373] [EC:3.2.1.52]
126958436  [KO:K04712] [EC:1.14.19.17 1.14.18.5]
126959023  [KO:K04716] [EC:3.1.3.-]
126959513  [KO:K00654] [EC:2.3.1.50]
126960081  [KO:K01202] [EC:3.2.1.46]
126960139  [KO:K24622]
126961451  [KO:K12348] [EC:3.5.1.23]
126962505  [KO:K12382]
126962507  [KO:K01634] [EC:4.1.2.27]
126963330  [KO:K12349] [EC:3.5.1.23]
126963334  [KO:K04714] [EC:2.7.8.27 3.1.4.62]
126963588  [KO:K04715] [EC:2.7.1.138]
126963935  [KO:K01019] [EC:2.8.2.11]
126964387  [KO:K09905] [EC:2.4.1.274 2.4.1.-]
Compound
C00065  L-Serine
C00154  Palmitoyl-CoA
C00195  N-Acylsphingosine
C00319  Sphingosine
C00346  Ethanolamine phosphate
C00550  Sphingomyelin
C00836  Sphinganine
C01120  Sphinganine 1-phosphate
C01190  Glucosylceramide
C01290  Lactosylceramide
C01747  Psychosine
C02686  Galactosylceramide
C02934  3-Dehydrosphinganine
C02960  Ceramide 1-phosphate
C03108  D-Glucosylsphingosine
C03272  Globoside
C03405  Lactosylceramide sulfate
C03640  Sphingosyl-phosphocholine
C04730  GM3
C04737  alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884  N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911  D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681  Ceramide 2-aminoethylphosphonate
C06062  Ceramide phosphoethanolamine
C06124  Sphingosine 1-phosphate
C06125  Sulfatide
C06126  Digalactosylceramide
C06127  Digalactosylceramide sulfate
C06128  GM4
C06135  GA2
C06136  GA1
C12126  Dihydroceramide
C12144  Phytosphingosine
C12145  Phytoceramide
C22467  Gangliotriaosylceramide-II3 sulfate
Reference
PMID:12011104
  Authors
Merrill AH Jr.
  Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
  Journal
J Biol Chem 277:25843-6 (2002)
DOI:10.1074/jbc.R200009200
Reference
PMID:10652340
  Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
  Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
  Journal
J Biol Chem 275:3462-8 (2000)
DOI:10.1074/jbc.275.5.3462
Reference
PMID:11305904
  Authors
Hannun YA, Luberto C, Argraves KM.
  Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
  Journal
Biochemistry 40:4893-903 (2001)
DOI:10.1021/bi002836k
Reference
PMID:1495423
  Authors
Merrill AH Jr, Wang E.
  Title
Enzymes of ceramide biosynthesis.
  Journal
Methods Enzymol 209:427-37 (1992)
DOI:10.1016/0076-6879(92)09053-6
Reference
PMID:8457204
  Authors
Hirschberg K, Rodger J, Futerman AH.
  Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
  Journal
Biochem J 290 ( Pt 3):751-7 (1993)
DOI:10.1042/bj2900751
Reference
PMID:10366774
  Authors
Dickson RC, Lester RL.
  Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1438:305-21 (1999)
DOI:10.1016/S1388-1981(99)00068-2
Related
pathway
mthb00260  Glycine, serine and threonine metabolism
mthb00601  Glycosphingolipid biosynthesis - lacto and neolacto series
mthb00603  Glycosphingolipid biosynthesis - globo and isoglobo series
mthb00604  Glycosphingolipid biosynthesis - ganglio series
KO pathway
ko00600   

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