KEGG   ORTHOLOGY: K00725
Entry
K00725                      KO                                     
Symbol
B4GALNT1, GALGT
Name
(N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92]
Pathway
map00600  Sphingolipid metabolism
map00604  Glycosphingolipid biosynthesis - ganglio series
map01100  Metabolic pathways
Disease
H00266  Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
  09107 Glycan biosynthesis and metabolism
   00604 Glycosphingolipid biosynthesis - ganglio series
    K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.92  (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
     K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
Glycosyltransferases [BR:ko01003]
 Glycan extension
  Glycolipid
   K00725  B4GALNT1, GALGT; (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
Other DBs
RN: R05938 R05939 R05946 R05952 R12962
GO: 0003947
CAZy: GT12
Genes
HSA: 2583(B4GALNT1)
PTR: 452021(B4GALNT1)
PPS: 100977739(B4GALNT1)
GGO: 101142085(B4GALNT1)
PON: 100441953(B4GALNT1)
NLE: 100596890(B4GALNT1)
MCC: 715317(B4GALNT1)
MCF: 101926458(B4GALNT1)
CSAB: 103238575(B4GALNT1)
CATY: 105587249(B4GALNT1)
PANU: 101005418(B4GALNT1)
TGE: 112634643(B4GALNT1)
RRO: 104682353(B4GALNT1)
RBB: 108519702(B4GALNT1)
TFN: 117089870(B4GALNT1)
PTEH: 111541797(B4GALNT1)
CJC: 100387150(B4GALNT1)
SBQ: 101035356(B4GALNT1)
CSYR: 103263166(B4GALNT1)
MMUR: 105877987(B4GALNT1)
LCAT: 123639596(B4GALNT1)
OGA: 100958711(B4GALNT1)
MMU: 14421(B4galnt1)
MCAL: 110302844(B4galnt1)
MPAH: 110326328(B4galnt1)
RNO: 64828(B4galnt1)
MCOC: 116075819(B4galnt1)
MUN: 110561316(B4galnt1)
CGE: 100764682(B4galnt1)
MAUA: 101833950(B4galnt1)
PLEU: 114704807(B4galnt1)
MORG: 121457348(B4galnt1)
AAMP: 119803561(B4galnt1)
NGI: 103742903(B4galnt1)
HGL: 101705101(B4galnt1)
CPOC: 100719351(B4galnt1)
CCAN: 109686096(B4galnt1)
DORD: 105988581(B4galnt1)
DSP: 122124387(B4galnt1)
NCAR: 124983376
OCU: 100340284(B4GALNT1)
OPI: 101527960(B4GALNT1)
TUP: 102495908(B4GALNT1)
CFA: 481129(B4GALNT1)
CLUD: 112677966(B4GALNT1)
VVP: 112922336(B4GALNT1)
VLG: 121491928(B4GALNT1)
AML: 100466312(B4GALNT1)
UMR: 103656939(B4GALNT1)
UAH: 113256372(B4GALNT1)
UAR: 123787304(B4GALNT1)
ELK: 111160216
LLV: 125106163
MPUF: 101692331(B4GALNT1)
ORO: 101384792(B4GALNT1)
EJU: 114214987(B4GALNT1)
ZCA: 113921972(B4GALNT1)
MLX: 118008424(B4GALNT1)
FCA: 101082581(B4GALNT1)
PYU: 121040864(B4GALNT1)
PBG: 122473825(B4GALNT1)
PTG: 102953164(B4GALNT1)
PPAD: 109270387(B4GALNT1)
AJU: 106975837(B4GALNT1)
HHV: 120248004(B4GALNT1)
BTA: 520159(B4GALNT1)
BOM: 102280706(B4GALNT1)
BIU: 109559314(B4GALNT1)
BBUB: 102409613(B4GALNT1)
CHX: 102173266(B4GALNT1)
OAS: 101119388(B4GALNT1)
ODA: 120857502(B4GALNT1)
CCAD: 122427339(B4GALNT1)
SSC: 100516440(B4GALNT1)
CFR: 102520114(B4GALNT1)
CBAI: 105062135(B4GALNT1)
CDK: 105100336(B4GALNT1)
VPC: 102530081(B4GALNT1)
BACU: 103016988(B4GALNT1)
LVE: 103088237(B4GALNT1)
OOR: 101281173(B4GALNT1)
DLE: 111173830(B4GALNT1)
PCAD: 102983599(B4GALNT1)
PSIU: 116760689(B4GALNT1)
ECB: 100053616(B4GALNT1)
EPZ: 103559776(B4GALNT1)
EAI: 106833013(B4GALNT1)
MYB: 102244087(B4GALNT1)
MYD: 102760120(B4GALNT1)
MMYO: 118651334(B4GALNT1)
MLF: 102434516(B4GALNT1)
MNA: 107546159(B4GALNT1)
PKL: 118730266(B4GALNT1)
HAI: 109390763(B4GALNT1)
DRO: 112319125(B4GALNT1)
SHON: 118975962(B4GALNT1)
AJM: 119035675(B4GALNT1)
PDIC: 114513768(B4GALNT1)
PHAS: 123812944(B4GALNT1)
MMF: 118623520(B4GALNT1)
RFQ: 117028118(B4GALNT1)
PALE: 102880239(B4GALNT1)
PGIG: 120604959(B4GALNT1)
PVP: 105307389(B4GALNT1)
RAY: 107501518(B4GALNT1)
MJV: 108409979(B4GALNT1)
TOD: 119248098(B4GALNT1)
SARA: 101557033(B4GALNT1)
LAV: 100656175(B4GALNT1)
TMU: 101357477
DNM: 101433475(B4GALNT1)
MDO: 100031466(B4GALNT1)
GAS: 123250467(B4GALNT1)
SHR: 100913439(B4GALNT1)
PCW: 110210985(B4GALNT1)
OAA: 114814766(B4GALNT1)
CJO: 107325778(B4GALNT1)
NMEL: 110392007
LSR: 110481834(B4GALNT1)
PMOA: 120499532(B4GALNT1)
OTC: 121334272(B4GALNT1)
PRUF: 121356353(B4GALNT1)
PHI: 102104849(B4GALNT1)
AROW: 112961595(B4GALNT1)
ASN: 102384074(B4GALNT1)
AMJ: 102576374(B4GALNT1)
CPOO: 109324403(B4GALNT1)
CMY: 102936553(B4GALNT1)
CPIC: 101945852(B4GALNT1)
TST: 117889048(B4GALNT1)
CABI: 116818857(B4GALNT1)
MRV: 120391165(B4GALNT1)
ACS: 100553349(b4galnt1)
PVT: 110070599(B4GALNT1)
SUND: 121921249(B4GALNT1)
PBI: 103067514(B4GALNT1)
PMUR: 107294728(B4GALNT1)
TSR: 106553723(B4GALNT1)
PGUT: 117666505(B4GALNT1)
VKO: 123029881(B4GALNT1)
PMUA: 114592946(B4GALNT1)
ZVI: 118078702(B4GALNT1)
GJA: 107120713(B4GALNT1)
STOW: 125428050(B4GALNT1)
XLA: 108709867(b4galnt1.S) 379299(b4galnt1.L)
XTR: 100145208(b4galnt1)
NPR: 108802621(B4GALNT1)
RTEM: 120929452(B4GALNT1)
BBUF: 120996074(B4GALNT1)
BGAR: 122932266(B4GALNT1)
DRE: 558684(b4galnt1a) 793635(b4galnt1b)
PPRM: 120463589(b4galnt1a) 120491381(b4galnt1b)
MAMB: 125259537(b4galnt1a) 125273705(b4galnt1b)
SMEO: 124390265(b4galnt1b)
TFD: 113658252(b4galnt1a) 113660538(b4galnt1b)
AMEX: 103039726(b4galnt1) 103043708
EEE: 113567787(b4galnt1) 113589183
TRU: 101063785 101064428(b4galnt1)
LCO: 104931956(b4galnt1) 104932572
CGOB: 115008865(b4galnt1) 115010627
ELY: 117257558(b4galnt1b) 117258938(b4galnt1a)
EFO: 125889274(b4galnt1b) 125891661(b4galnt1a)
PLEP: 121939030 121946469(b4galnt1a) 121950679(b4galnt1b)
SLUC: 116039006(b4galnt1a) 116041660(b4galnt1b)
ECRA: 117943914(b4galnt1b) 117947769(b4galnt1a)
ESP: 116688378(b4galnt1) 116692690
PFLV: 114554065(b4galnt1) 114559465
GAT: 120829097(b4galnt1a) 120835599(b4galnt1b)
PPUG: 119223254 119229857(b4galnt1b)
MSAM: 119886148(b4galnt1b) 119905488(b4galnt1a)
CUD: 121504305 121506149(b4galnt1b) 121518213(b4galnt1a)
ALAT: 119020492(b4galnt1b) 119023434(b4galnt1a)
ONL: 100701263(b4galnt1) 100705425
OAU: 116325820(b4galnt1a) 116333850(b4galnt1b)
OLA: 101155420(b4galnt1) 101171003
OML: 112145405(b4galnt1b) 112159647(b4galnt1a)
PRET: 103465386(b4galnt1) 103467344
GAF: 122832697(b4galnt1a) 122834697 122834726(b4galnt1b)
CVG: 107082147(b4galnt1) 107086793
CTUL: 119776671(b4galnt1b) 119782168
GMU: 124856483(b4galnt1b) 124861330(b4galnt1a)
NFU: 107385684(b4galnt1) 107390873
KMR: 108228644(b4galnt1a) 108235553(b4galnt1b)
ALIM: 106518031(b4galnt1) 106524945
NWH: 119412559(b4galnt1b) 119416969(b4galnt1a)
AOCE: 111566651(b4galnt1) 111587243
MCEP: 124996938(b4galnt1a) 125007198(b4galnt1b)
CSEM: 103385079 103385954(b4galnt1)
POV: 109629415(b4galnt1) 109630534
SSEN: 122768416(b4galnt1b) 122777098(b4galnt1a)
HHIP: 117761296(b4galnt1b) 117765024(b4galnt1a)
HSP: 118105510(b4galnt1b) 118111613(b4galnt1a)
LCF: 108876488 108881464(b4galnt1)
SDU: 111219289 111221963(b4galnt1)
SLAL: 111667834(b4galnt1) 111668982
XGL: 120783424(b4galnt1b) 120804023(b4galnt1a)
HCQ: 109522137(b4galnt1) 109531384
BPEC: 110164780 110168375(b4galnt1)
BSPL: 114856333(b4galnt1b) 114859002(b4galnt1a)
OTW: 112216357 112217564(b4galnt1b) 112254603
OMY: 110494320 110528114(b4galnt1b) 110532694
OGO: 124003500 124019822(b4galnt1b) 124032285
SALP: 111966771 111966811 111970082(b4galnt1)
ELS: 105005742 105013542 105017218(b4galnt1)
SFM: 108918587(b4galnt1) 108939037
PKI: 111851086 111854415(b4galnt1) 111860628
AANG: 118207800 118211247(b4galnt1b)
LOC: 102693606(b4galnt1)
PSPA: 121308998(b4galnt1b)
LCM: 102353417 102354362(B4GALNT1)
RTP: 109925717(b4galnt1)
 » show all
Reference
PMID:7980468
  Authors
Hidari JK, Ichikawa S, Furukawa K, Yamasaki M, Hirabayashi Y
  Title
beta 1-4N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta 1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F.
  Journal
Biochem J 303 ( Pt 3):957-65 (1994)
DOI:10.1042/bj3030957
  Sequence
[rno:64828]
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