KEGG   PATHWAY: aang04070
Entry
aang04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Anguilla anguilla (European eel)
Class
Environmental Information Processing; Signal transduction
Pathway map
aang04070  Phosphatidylinositol signaling system
aang04070

Organism
Anguilla anguilla (European eel) [GN:aang]
Gene
118212965  phosphatidylinositol 4-kinase alpha-like isoform X1 [KO:K00888] [EC:2.7.1.67]
118237438  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b [KO:K00888] [EC:2.7.1.67]
118233943  phosphatidylinositol 4-kinase beta-like isoform X1 [KO:K19801] [EC:2.7.1.67]
118236878  pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
118221858  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
118217683  phosphatidylinositol 4-kinase type 2-alpha-like [KO:K13711] [EC:2.7.1.67]
118231649  phosphatidylinositol 4-kinase type 2-beta-like [KO:K13711] [EC:2.7.1.67]
118227357  pi4k2b; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
118207851  phosphatidylinositol-3-phosphatase SAC1-B-like isoform X1 [KO:K21797] [EC:3.1.3.-]
118233840  phosphatidylinositol-3-phosphatase SAC1-B [KO:K21797] [EC:3.1.3.-]
118218130  inpp5f; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
118229002  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [KO:K00889] [EC:2.7.1.68]
118212374  phosphatidylinositol 4-phosphate 5-kinase type-1 beta-like isoform X1 [KO:K00889] [EC:2.7.1.68]
118231811  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like isoform X1 [KO:K00889] [EC:2.7.1.68]
118206718  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
118226252  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
118234222  pip5k1aa; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a [KO:K00889] [EC:2.7.1.68]
118223511  inositol polyphosphate 5-phosphatase OCRL-like isoform X1 [KO:K01099] [EC:3.1.3.36]
118232777  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
118236771  inositol polyphosphate 5-phosphatase OCRL-like isoform X1 [KO:K01099] [EC:3.1.3.36]
118212695  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV isoform X1 [KO:K20278] [EC:3.1.3.36]
118235526  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
118209150  synaptojanin-1-like [KO:K20279] [EC:3.1.3.36]
118209617  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
118229817  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
118223556  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
118211053  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
118225726  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
118228853  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
118206252  phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1 [KO:K02649]
118225456  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
118212644  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
118225588  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
118218023  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
118220705  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
118225518  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
118222228  inppl1b; inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
118209416  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A isoform X1 [KO:K15909] [EC:3.1.3.86]
118224397  inositol polyphosphate-4-phosphatase type I A-like isoform X1 [KO:K01109] [EC:3.1.3.66]
118231840  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
118213588  inpp4aa; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
118223839  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
118223712  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
118234988  myotubularin-like [KO:K01108] [EC:3.1.3.64 3.1.3.95]
118209442  myotubularin-related protein 2-like [KO:K18081] [EC:3.1.3.64 3.1.3.95]
118235744  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
118224392  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
118235777  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
118206624  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
118212600  myotubularin-related protein 3-like isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
118235996  mtmr8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
118231021  mtmr7a; myotubularin-related protein 7a [KO:K18083] [EC:3.1.3.64 3.1.3.95]
118225612  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
118227791  mtmr7b; myotubularin-related protein 7b [KO:K18083] [EC:3.1.3.64 3.1.3.95]
118211071  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
118211410  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like isoform X1 [KO:K00920] [EC:2.7.1.149]
118225357  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
118233797  pip4k2ab; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
118208626  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
118211335  type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase-like [KO:K13084] [EC:3.1.3.78]
118231305  type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A [KO:K13084] [EC:3.1.3.78]
118234635  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
118232028  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
118215214  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha-like [KO:K00923] [EC:2.7.1.154]
118211495  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
118231141  pik3c2g; LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
118227175  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
118222480  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
118222607  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
118229574  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
118229604  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
118230603  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like isoform X1 [KO:K05858] [EC:3.1.4.11]
118230605  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
118215964  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A-like isoform X1 [KO:K05857] [EC:3.1.4.11]
118223579  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4-like [KO:K05857] [EC:3.1.4.11]
118224931  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
118214183  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4-like isoform X1 [KO:K05857] [EC:3.1.4.11]
118234126  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like isoform X1 [KO:K05857] [EC:3.1.4.11]
118221774  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A-like isoform X1 [KO:K05857] [EC:3.1.4.11]
118218425  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1-like isoform X1 [KO:K05860] [EC:3.1.4.11]
118221825  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
118225935  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like [KO:K01116] [EC:3.1.4.11]
118208555  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
118228424  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
118231142  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
118217809  inositol polyphosphate multikinase-like [KO:K00915] [EC:2.7.1.140 2.7.1.151]
118221123  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
118210165  itpkcb; inositol-trisphosphate 3-kinase Cb isoform X1 [KO:K00911] [EC:2.7.1.127]
118230068  itpkb; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
118213583  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
118218007  inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
118229489  inositol-tetrakisphosphate 1-kinase-like isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
118231456  inositol-tetrakisphosphate 1-kinase-like [KO:K00913] [EC:2.7.1.159 2.7.1.134]
118208907  inositol-tetrakisphosphate 1-kinase-like [KO:K00913] [EC:2.7.1.159 2.7.1.134]
118211841  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
118211076  inositol hexakisphosphate kinase 2-like [KO:K07756] [EC:2.7.4.21]
118211283  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
118208094  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
118215748  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2-like isoform X1 [KO:K13024] [EC:2.7.4.24]
118212641  ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
118227055  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2-like isoform X1 [KO:K13024] [EC:2.7.4.24]
118211820  inpp1; inositol polyphosphate 1-phosphatase isoform X1 [KO:K01107] [EC:3.1.3.57]
118224642  impa2; inositol monophosphatase 2 isoform X1 [KO:K01092] [EC:3.1.3.25]
118226095  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
118226570  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
118233874  inositol monophosphatase 1-like isoform X1 [KO:K01092] [EC:3.1.3.25]
118233875  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
118226230  inositol monophosphatase 3-like [KO:K15759] [EC:3.1.3.7]
118233032  inositol monophosphatase 3-like [KO:K15759] [EC:3.1.3.7]
118236398  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
118215376  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
118222876  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
118210202  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
118216550  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
118223219  diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
118210555  dgkab; diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
118223744  diacylglycerol kinase eta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
118224539  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
118231757  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
118232361  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
118207469  dgkaa; diacylglycerol kinase, alpha a isoform X1 [KO:K00901] [EC:2.7.1.107]
118214094  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
118227626  dgkza; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
118206404  cds1; phosphatidate cytidylyltransferase 1 isoform X1 [KO:K00981] [EC:2.7.7.41]
118213464  phosphatidate cytidylyltransferase 2-like isoform X1 [KO:K00981] [EC:2.7.7.41]
118237375  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
118220279  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
118211513  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
118207405  inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
118219247  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
118208164  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
118219598  protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
118216704  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
118220309  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
118221921  prkcg; protein kinase C alpha type [KO:K19663] [EC:2.7.11.13]
118235483  calm1a; calmodulin-1a [KO:K02183]
118209739  calm3a; calmodulin 3a (phosphorylase kinase, delta) [KO:K02183]
118229986  calm1b; calmodulin-1b [KO:K02183]
118223713  calm3b; calmodulin 3b (phosphorylase kinase, delta) [KO:K02183]
118211174  calglandulin-like [KO:K02183]
118218186  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
118220834  calmodulin-1 [KO:K02183]
118215159  calml4b; calmodulin-like protein 4 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
aang04020  Calcium signaling pathway
aang04144  Endocytosis
aang04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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