KEGG   PATHWAY: ipu00564
Entry
ipu00564                    Pathway                                
Name
Glycerophospholipid metabolism - Ictalurus punctatus (channel catfish)
Class
Metabolism; Lipid metabolism
Pathway map
ipu00564  Glycerophospholipid metabolism
ipu00564

Module
ipu_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:ipu00564]
ipu_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:ipu00564]
ipu_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:ipu00564]
Other DBs
GO: 0006650
Organism
Ictalurus punctatus (channel catfish) [GN:ipu]
Gene
108255083  gpd1b; glycerol-3-phosphate dehydrogenase 1b [KO:K00006] [EC:1.1.1.8]
108270280  glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
108274829  gpd1c; glycerol-3-phosphate dehydrogenase 1c [KO:K00006] [EC:1.1.1.8]
108264983  gpd1a; glycerol-3-phosphate dehydrogenase 1a [KO:K00006] [EC:1.1.1.8]
108273160  glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
108265855  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
108274217  glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
108265165  glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
108277038  gpat4; glycerol-3-phosphate acyltransferase 4 isoform X1 [KO:K13506] [EC:2.3.1.15]
108279044  glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
108255643  agpat9l; glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
108278901  1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
108260841  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
100528239  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
108263135  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
108263334  lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
108269814  mboat2a; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
108257786  mboat2b; lysophospholipid acyltransferase 2b isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
108272131  lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
108260471  dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
108257502  gnpat2; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
108274373  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X2 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
108277036  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
108265984  phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
108268250  phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
108258058  phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
108280716  plpp2a; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
108257126  ppap2d; phosphatidic acid phosphatase type 2D [KO:K01080] [EC:3.1.3.4]
108275291  phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
108271928  zgc:123305 isoform X2 [KO:K15728] [EC:3.1.3.4]
108268131  phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
108270137  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
108277196  phospholipid phosphatase 5 isoform X2 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
108262841  phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
108272902  diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
108267497  si:dkey-172j4.3; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
108277589  diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
108266790  diacylglycerol kinase eta isoform X3 [KO:K00901] [EC:2.7.1.107]
108266954  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
108259213  dgkza; diacylglycerol kinase zeta isoform X11 [KO:K00901] [EC:2.7.1.107]
108280052  diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
108277157  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
108274966  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
108276149  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
108274771  cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
108265319  cept1a; choline/ethanolaminephosphotransferase 1a [KO:K13644] [EC:2.7.8.1 2.7.8.2]
100305100  cept1b; choline/ethanolaminephosphotransferase 1b isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
108266656  si:ch211-168k14.2; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
108278083  pld1a; phospholipase D1a isoform X1 [KO:K01115] [EC:3.1.4.4]
108279749  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
108260096  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
108259766  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
108256388  pld1b; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
108259951  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
108264303  5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
108269620  5'-3' exonuclease PLD4 isoform X1 [KO:K16860] [EC:3.1.4.4]
100528492  lcat; phosphatidylcholine-sterol acyltransferase precursor [KO:K00650] [EC:2.3.1.43]
108263034  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
108277191  pla2g3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
108255707  group 3 secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
108263807  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
108264938  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
108277361  phospholipase A2 [KO:K01047] [EC:3.1.1.4]
108258821  phospholipase A2 [KO:K01047] [EC:3.1.1.4]
108256767  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
108278205  proca1; uncharacterized protein proca1 [KO:K01047] [EC:3.1.1.4]
108277761  pla2g4aa; cytosolic phospholipase A2 isoform X2 [KO:K16342] [EC:3.1.1.4]
108257972  pla2g4ab; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
108269587  cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
108270284  cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
108270285  cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
108259399  85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
108269596  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
108257774  phospholipase B1, membrane-associated-like isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
108269896  phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
108257913  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
108269055  phospholipase A and acyltransferase 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
108259642  lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
108272334  lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
108272386  lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
108261003  lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
108266630  lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
108268102  acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
108268878  group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
100528374  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
108278974  pnpla7a; patatin-like phospholipase domain-containing protein 7a isoform X2 [KO:K14676] [EC:3.1.1.5]
108258612  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
108255960  pnpla7b; patatin-like phospholipase domain-containing protein 7 isoform X1 [KO:K14676] [EC:3.1.1.5]
108257980  glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
108262900  chata; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
108273528  choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
108267799  ache; acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
108264160  si:dkey-30c15.17; cAMP-regulated D2 protein isoform X1 [KO:K01049] [EC:3.1.1.7]
124626876  choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
124628079  choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
108261429  probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
108273983  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
128628685  probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
108256564  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
108264716  pcyt1ab; phosphate cytidylyltransferase 1A, choline b [KO:K00968] [EC:2.7.7.15]
108267677  pcyt1aa; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
108278471  pcyt1bb; phosphate cytidylyltransferase 1B, choline b [KO:K00968] [EC:2.7.7.15]
124628309  choline-phosphate cytidylyltransferase A-like isoform X1 [KO:K00968] [EC:2.7.7.15]
108275849  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
108254941  ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
108279626  ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
108269085  zgc:113516; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
108259513  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
108277112  ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
108275150  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
108267613  ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
100528737  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
108255893  phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
108255741  cds2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
108266535  phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
108256259  ptdss1a; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
108257397  ptdss1b; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
108274776  phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
108260240  phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
108274105  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
108270394  cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
100528715  tafazzin [KO:K13511] [EC:2.3.1.-]
108257857  acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
108278459  CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
108264261  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
108264268  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
108264271  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
108264277  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
ipu00010  Glycolysis / Gluconeogenesis
ipu00260  Glycine, serine and threonine metabolism
ipu00561  Glycerolipid metabolism
ipu00562  Inositol phosphate metabolism
ipu00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
ipu00565  Ether lipid metabolism
ipu00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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