KEGG   PATHWAY: mcep04070
Entry
mcep04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Mugil cephalus (flathead mullet)
Class
Environmental Information Processing; Signal transduction
Pathway map
mcep04070  Phosphatidylinositol signaling system
mcep04070

Organism
Mugil cephalus (flathead mullet) [GN:mcep]
Gene
125011953  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b isoform X1 [KO:K00888] [EC:2.7.1.67]
124996682  pi4kaa; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
125019797  phosphatidylinositol 4-kinase beta-like [KO:K19801] [EC:2.7.1.67]
125016131  pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
125004398  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
125004422  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
125019865  sacm1la; phosphatidylinositol-3-phosphatase SAC1-A [KO:K21797] [EC:3.1.3.-]
125016976  phosphatidylinositol-3-phosphatase SAC1-B [KO:K21797] [EC:3.1.3.-]
125018988  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
125011727  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
125016611  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like isoform X1 [KO:K00889] [EC:2.7.1.68]
125020356  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68]
125009346  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
124997093  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta A [KO:K00889] [EC:2.7.1.68]
125011241  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like isoform X1 [KO:K00889] [EC:2.7.1.68]
125015999  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
125007802  ocrL; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
125011961  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
125020708  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
125024403  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
125013336  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
125009384  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
125010793  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
125012779  phosphatidylinositol 3-kinase regulatory subunit alpha-like [KO:K02649]
124996387  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
125009281  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) [KO:K02649]
125009744  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
125010445  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
125011199  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
125022104  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
125018803  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
125008966  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
125013387  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A isoform X1 [KO:K15909] [EC:3.1.3.86]
125007851  inppl1b; inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
125018006  inpp4aa; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
125003762  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
125000976  inositol polyphosphate-4-phosphatase type I A-like isoform X1 [KO:K01109] [EC:3.1.3.66]
125017580  1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
124998035  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
125022194  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125021666  mtmr2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125021075  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
125012714  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
124995907  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125008565  mtmr7a; myotubularin-related protein 7A [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125006240  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
125024457  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
125006870  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like isoform X1 [KO:K00920] [EC:2.7.1.149]
125003897  phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
125004201  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
125020005  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
125009150  type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase-like [KO:K13084] [EC:3.1.3.78]
125010257  pip4p1a; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A isoform X1 [KO:K13084] [EC:3.1.3.78]
124997841  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
125006361  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
125015398  pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
125014973  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
125023608  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
124999051  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
125018743  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
125008027  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
124998714  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4-like isoform X1 [KO:K05858] [EC:3.1.4.11]
125022998  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A-like [KO:K05857] [EC:3.1.4.11]
125017610  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
124995715  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
125000697  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
125010087  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like isoform X1 [KO:K05857] [EC:3.1.4.11]
124998254  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
125022327  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
125021358  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
125009887  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like isoform X1 [KO:K01116] [EC:3.1.4.11]
125015418  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
125015399  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
125022164  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
125023448  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
124999123  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
125013609  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
125008226  si:ch73-22a13.3; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
125020805  itpkca; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
125018566  inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
125023572  itpk1b; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
125013256  inositol-tetrakisphosphate 1-kinase-like [KO:K00913] [EC:2.7.1.159 2.7.1.134]
125006723  ippK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
125006749  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
125006792  inositol hexakisphosphate kinase 2-like [KO:K07756] [EC:2.7.4.21]
125007315  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
125014584  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
125005271  ppip5k1a; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
125006141  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
124995648  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
124995649  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
125011034  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
125010548  bpnt2; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
125006512  dgkab; diacylglycerol kinase, alpha B [KO:K00901] [EC:2.7.1.107]
125012095  dgkaa; diacylglycerol kinase, alpha A [KO:K00901] [EC:2.7.1.107]
125015242  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
125016779  dgkB; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
125013712  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
125017477  dgkH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
125018276  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
125006721  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
125000168  dgkI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
125001181  diacylglycerol kinase zeta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
125008597  diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
125004433  dgkE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
125011951  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
125012452  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
124998287  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
125006285  inositol 1,4,5-trisphosphate receptor type 1-like isoform X1 [KO:K04958]
125007204  inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
125015051  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
125008315  itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
125004243  prkcaa; protein kinase C, alpha, a isoform X1 [KO:K02677] [EC:2.7.11.13]
124997961  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
125003616  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
124997521  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
125015974  prkcg; protein kinase C alpha type [KO:K19663] [EC:2.7.11.13]
125024233  calmodulin-1 [KO:K02183]
125006593  calglandulin-like [KO:K02183]
125014343  calml4b; calmodulin-like protein 4 [KO:K02183]
125013316  calm3a; calmodulin 3a (phosphorylase kinase, delta) [KO:K02183]
125018763  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
125005003  calmodulin-like protein 4 [KO:K02183]
124998844  calmodulin-1 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
mcep04020  Calcium signaling pathway
mcep04144  Endocytosis
mcep04510  Focal adhesion
KO pathway
ko04070   
LinkDB

DBGET integrated database retrieval system