KEGG   PATHWAY: oma03083
Entry
oma03083                    Pathway                                
Name
Polycomb repressive complex - Oenanthe melanoleuca (Eastern black-eared wheatear)
Class
Genetic Information Processing; Chromosome
Pathway map
oma03083  Polycomb repressive complex
oma03083

Organism
Oenanthe melanoleuca (Eastern black-eared wheatear) [GN:oma]
Gene
130263963  EZH1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
130248948  EZH2; histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
130255337  EED; polycomb protein EED isoform X1 [KO:K11462]
130260410  SUZ12; polycomb protein SUZ12 [KO:K11463]
130262174  RBBP4; histone-binding protein RBBP4 isoform X1 [KO:K10752]
130258609  RBBP7; histone-binding protein RBBP7 [KO:K11659]
130263331  PHF1; PHD finger protein 1 [KO:K11467]
130256052  MTF2; metal-response element-binding transcription factor 2 isoform X1 [KO:K11485]
130260185  PHF19; PHD finger protein 19 [KO:K11486]
130254732  LCOR; ligand-dependent corepressor isoform X1 [KO:K26260]
130267038  AEBP2; zinc finger protein AEBP2 isoform X1 [KO:K17452]
130249191  JARID2; protein Jumonji [KO:K11478]
130258281  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 [KO:K08588] [EC:3.4.19.12]
130250603  ASXL2; putative Polycomb group protein ASXL2 [KO:K11471]
130261148  ASXL1; polycomb group protein ASXL1 [KO:K11471]
130248778  ASXL3; putative Polycomb group protein ASXL3 [KO:K11471]
130253195  OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
130262918  HCFC1; LOW QUALITY PROTEIN: host cell factor 1 [KO:K14966]
130253527  YY1; transcriptional repressor protein YY1 [KO:K09201]
130255801  MBD5; methyl-CpG-binding domain protein 5 [KO:K23219]
130259490  FOXK1; forkhead box protein K1 [KO:K09404]
130260510  FOXK2; forkhead box protein K2 [KO:K09404]
130256240  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
130264232  PCGF2; polycomb group RING finger protein 2 isoform X1 [KO:K11460]
130260587  CBX2; chromobox protein homolog 2 [KO:K11451]
130260576  CBX4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
130262538  CBX6; chromobox protein homolog 6 isoform X1 [KO:K11453]
130264934  CBX7; chromobox protein homolog 7 isoform X1 [KO:K11454]
130260578  CBX8; chromobox protein homolog 8 isoform X1 [KO:K11455]
130262046  PHC1; polyhomeotic-like protein 1 isoform X1 [KO:K11456]
130261616  PHC2; polyhomeotic-like protein 2 isoform X1 [KO:K11457]
130257014  PHC3; polyhomeotic-like protein 3 isoform X1 [KO:K11458]
130257152  SCML2; sex comb on midleg-like protein 2 [KO:K11465]
130262187  SCMH1; polycomb protein SCMH1 isoform X1 [KO:K11461]
130248293  SFMBT2; scm-like with four MBT domains protein 2 isoform X1 [KO:K26269]
130258137  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
130252132  UBE2D3; ubiquitin-conjugating enzyme E2 D3 [KO:K06689] [EC:2.3.2.23]
130254699  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
130258657  UBE2D2; ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
130251424  USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 [KO:K11844] [EC:3.4.19.12]
130257216  USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [KO:K11844] [EC:3.4.19.12]
130258498  RYBP; RING1 and YY1-binding protein [KO:K11469]
130262421  YAF2; YY1-associated factor 2 [KO:K11468]
130252089  PCGF1; polycomb group RING finger protein 1 isoform X1 [KO:K11487]
130259853  KDM2B; lysine-specific demethylase 2B isoform X1 [KO:K10276] [EC:1.14.11.27]
130253482  KDM2A; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
130248917  BCOR; BCL-6 corepressor isoform X1 [KO:K23215]
130252932  BCORL1; BCL-6 corepressor-like protein 1 [KO:K26199]
130258942  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
130259165  USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
130265152  PCGF3; polycomb group RING finger protein 3 isoform X1 [KO:K11488]
130254754  PCGF5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
130260947  AUTS2; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
130259630  FBRSL1; fibrosin-1-like protein isoform X1 [KO:K26254]
130264036  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
130249753  TEX10; testis-expressed protein 10 isoform X1 [KO:K14827]
130248224  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
130259078  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
130254994  PCGF6; polycomb group RING finger protein 6 isoform X1 [KO:K11470]
130266741  E2F6; transcription factor E2F6 isoform X1 [KO:K09390]
130248542  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
130254519  MAX; protein max isoform X1 [KO:K04453]
130253782  MGA; MAX gene-associated protein isoform X1 [KO:K23399]
130251320  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 [KO:K24387]
130261469  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 isoform X1 [KO:K24387]
130262096  lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
130248226  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 isoform X1 [KO:K24387]
130250092  CBX3; chromobox protein homolog 3 isoform X1 [KO:K11586]
130260265  WDR5; WD repeat-containing protein 5 [KO:K14963]
130251299  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
130262361  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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