KEGG   PATHWAY: rn00230
Entry
rn00230                     Pathway                                
Name
Purine metabolism
Class
Metabolism; Nucleotide metabolism
Pathway map
rn00230  Purine metabolism
rn00230

Module
M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rn00230]
M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rn00230]
M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rn00230]
M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rn00230]
M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rn00230]
M00546  Purine degradation, xanthine => urea [PATH:rn00230]
M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rn00230]
M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rn00230]
M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:rn00230]
Other DBs
GO: 0006163 0042278
Reaction
R00086  ATP phosphohydrolase
R00087  ATP diphosphohydrolase (diphosphate-forming); ATP pyrophosphohydrolase
R00089  ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)
R00122  ADP phosphohydrolase
R00125  P1,P4-bis(5'-adenosyl)-tetraphosphate nucleotidebisphosphohydrolase
R00126  ADP:ATP adenylyltransferase
R00127  ATP:AMP phosphotransferase
R00128  adenosine-tetraphosphate phosphohydrolase
R00150  ATP:carbamate phosphotransferase
R00181  AMP aminohydrolase
R00182  AMP phosphoribohydrolase
R00183  adenosine 5'-monophosphate phosphohydrolase
R00184  P1,P4-bis(5'-adenosyl)-tetraphosphate adenylohydrolase
R00185  ATP:adenosine 5'-phosphotransferase
R00187  P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase
R00190  AMP:diphosphate phospho-D-ribosyltransferase
R00191  adenosine 3',5'-phosphate 5'-nucleotidohydrolase
R00322  5'-acetylphosphoadenosine acetylhydrolase
R00328  GDP phosphohydrolase
R00330  ATP:GDP phosphotransferase
R00331  ATP:nucleoside-diphosphate phosphotransferase
R00332  ATP:GMP phosphotransferase
R00333  nucleoside-triphosphate:AMP phosphotransferase
R00335  GTP phosphohydrolase
R00336  guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase
R00426  GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase
R00429  ATP:GTP 3'-diphosphotransferase
R00434  GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)
R00469  (S)-ureidoglycolate amidohydrolase (decarboxylating)
R00507  3'-phosphoadenylyl-sulfate sulfohydrolase; 3'-phosphoadenylyl-sulfate nucleotidohydrolase
R00509  ATP:adenylylsulfate 3'-phosphotransferase
R00529  ATP:sulfate adenylyltransferase
R00719  ITP phosphohydrolase
R00720  inosine 5'-triphosphate pyrophosphohydrolase
R00722  ATP:IDP phosphotransferase
R00723  inosine 5'-tetraphosphate phosphohydrolase
R00776  (S)-ureidoglycolate urea-lyase (glyoxylate-forming)
R00961  IDP phosphohydrolase; inosine diphosphate phosphatase
R01049  ATP:D-ribose-5-phosphate diphosphotransferase
R01053  ribose-5-phosphate:ammonia ligase (ADP-forming)
R01054  ADP-ribose ribophosphohydrolase
R01057  D-ribose 1,5-phosphomutase
R01072  5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)
R01083  N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
R01126  inosine 5'-monophosphate phosphohydrolase
R01127  IMP 1,2-hydrolase (decyclizing)
R01130  IMP:NAD+ oxidoreductase
R01131  ATP:inosine 5'-phosphotransferase
R01132  IMP:diphosphate phospho-D-ribosyltransferase
R01134  inosine-5'-phosphate:NADP+ oxidoreductase (aminating); NADH:guanosine-5'-phosphate oxidoreductase (deaminating)
R01135  IMP:L-aspartate ligase (GDP-forming)
R01137  ATP:dADP phosphotransferase
R01227  guanosine 5'-monophosphate phosphohydrolase
R01228  ATP:guanosine 5'-phosphotransferase
R01229  GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase
R01230  xanthosine-5'-phosphate:ammonia ligase (AMP-forming)
R01231  xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
R01232  P1,P4-bis(5'-guanosyl)-tetraphosphate guanylylhydrolase
R01234  guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase
R01244  adenine aminohydrolase
R01245  adenosine ribohydrolase
R01423  5'-benzoylphosphoadenosine benzoylhydrolase
R01547  ATP:dAMP phosphotransferase
R01560  adenosine aminohydrolase
R01561  adenosine:phosphate alpha-D-ribosyltransferase
R01562  adenosine 3'-phosphate phosphohydrolase
R01618  APS:ATP adenylyltransferase
R01676  guanine aminohydrolase
R01677  guanosine ribohydrolase
R01690  5'-butyrylphosphoinosine butyrylhydrolase
R01768  hypoxanthine:NAD+ oxidoreductase
R01769  hypoxanthine:oxygen oxidoreductase
R01770  inosine ribohydrolase
R01855  2'-deoxyguanosine 5'-triphosphate diphosphohydrolase
R01856  dGTP triphosphohydrolase
R01857  ATP:dGDP phosphotransferase
R01863  inosine:phosphate alpha-D-ribosyltransferase
R01885  
R01967  ATP:deoxyguanosine 5'-phosphotransferase
R01968  2'-deoxyguanosine 5'-monophosphate phosphohydrolase
R01969  deoxyguanosine:orthophosphate ribosyltransferase
R02014  2'-deoxyadenosine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase
R02017  2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
R02019  2'-deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
R02020  2'-deoxyguanosine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase
R02088  2'-deoxyadenosine 5'-monophosphate phosphohydrolase
R02089  ATP:deoxyadenosine 5'-phosphotransferase
R02090  ATP:dGMP phosphotransferase
R02103  xanthine:NAD+ oxidoreductase
R02106  urate:oxygen oxidoreductase
R02107  xanthine:oxygen oxidoreductase
R02141  
R02142  XMP:pyrophosphate phosphoribosyltransferase
R02143  xanthosine ribohydrolase
R02147  guanosine:phosphate alpha-D-ribosyltransferase
R02148  guanosine 3'-phosphate phosphohydrolase
R02297  xanthosine:orthophosphate ribosyltransferase
R02422  allantoate amidinohydrolase
R02423  allantoate amidinohydrolase (decarboxylating)
R02425  (S)-allantoin amidohydrolase
R02556  deoxyadenosine aminohydrolase
R02557  deoxyadenosine:orthophosphate ribosyltransferase
R02646  urate-3-ribonucleoside:phosphate D-ribosyltransferase
R02719  xanthosine 5'-phosphate phosphohydrolase
R02720  XTP pyrophosphohydrolase; XTP diphosphohydrolase (diphosphate-forming)
R02729  5-formiminotetrahydrofolate:glycine N-formiminotransferase
R02748  deoxyinosine:orthophosphate ribosyltransferase
R02805  P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase
R02935  (S)-ureidoglycolate:NAD+ oxidoreductase
R02936  (S)-ureidoglycolate:NADP+ oxidoreductase
R02937  carbamoyl-phosphate:oxamate carbamoyltransferase
R03409  guanosine 3'-diphosphate 5'-triphosphate 5'-phosphohydrolase
R03530  ATP:dIDP phosphotransferase
R03531  2'-deoxyinosine-5'-triphosphate pyrophosphohydrolase; dITP diphosphohydrolase (diphosphate-forming)
R03537  2',3'-cyclic AMP 3'-nucleotidohydrolase
R03925  allantoin racemase
R04026  
R04144  5-phospho-D-ribosylamine:glycine ligase (ADP-forming)
R04208  2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)
R04209  1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase
R04325  10-formyltetrahydrofolate:5'-phosphoribosylglycinamide formyltransferase
R04378  1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide:pyrophosphate phosphoribosyltransferase
R04463  5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)
R04559  1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
R04560  10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase
R04591  1-(5-phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)
R04731  4-aminoimidazole aminohydrolase
R04732  
R04857  
R05135  2',3'-cyclic GMP 3'-nucleotidohydrolase
R05554  ureidoglycine aminohydrolase; (S)-ureidoglycine aminohydrolase
R06601  5-hydroxyisourate amidohydrolase
R06604  5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate carboxy-lyase [(S)-allantoin-forming]
R06605  
R06974  formate:N1-(5-phospho-beta-D-ribosyl)glycinamide ligase (ADP-forming)
R06975  formate:5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ligase (ADP-forming); 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase
R07404  5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming)
R07405  5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase
R09514  urate,NADH:oxygen oxidoreductase (5-hydroxyisourate forming)
R10235  deoxyinosine diphosphate phosphatase
R10836  AMP:phosphate (5-phospho-alpha-D-ribosyl)transferase
R10908  (S)-ureidoglycine:glyoxylate aminotransferase
R11617  oxamate amidohydrolase
R11633  GTP:formate 2'-oxidoreductase
R11634  ATP:formate 2'-oxidoreductase
R12703  
R12786  dGMP:L-aspartate ligase (ADP-forming)
R12851  adenylosuccinate lyase
R12852  guanylate kinase
R12853  nucleoside-diphosphate kinase
R12987  adenine:NAD+ oxidoreductase
R12988  8-hydroxyadenine:NAD+ oxidoreductase
R12989  adenine:oxygen oxidoreductase
R12990  8-hydroxyadenine:oxygen oxidoreductase
R13420  urea amidohydrolase
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rn00030  Pentose phosphate pathway
rn00220  Arginine biosynthesis
rn00250  Alanine, aspartate and glutamate metabolism
rn00260  Glycine, serine and threonine metabolism
rn00340  Histidine metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn00730  Thiamine metabolism
rn00740  Riboflavin metabolism
rn00790  Folate biosynthesis
KO pathway
ko00230   

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