KEGG   PATHWAY: srx04142
Entry
srx04142                    Pathway                                
Name
Lysosome - Sinocyclocheilus rhinocerous
Description
Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy.
Class
Cellular Processes; Transport and catabolism
Pathway map
srx04142  Lysosome
srx04142

Other DBs
GO: 0005764
Organism
Sinocyclocheilus rhinocerous [GN:srx]
Gene
107755711  V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
107731011  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
107731789  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
107710948  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
107726380  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
107713355  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
107733440  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
107744440  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
107744150  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
107742255  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
107754956  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
107749787  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
107740464  atp6v0d1; V-type proton ATPase subunit d 1 [KO:K02146]
107746916  atp6v1h; V-type proton ATPase subunit H [KO:K02144]
107732543  V-type proton ATPase subunit H-like [KO:K02144]
107716175  V-type proton ATPase subunit S1-like [KO:K03662]
107737500  V-type proton ATPase subunit S1-like [KO:K03662]
107754334  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
107753042  LOW QUALITY PROTEIN: V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
107745898  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
107752728  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
107730801  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
107713045  V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
107746935  dmX-like protein 2 [KO:K24155]
107728253  LOW QUALITY PROTEIN: dmX-like protein 1 [KO:K24155]
107747624  dmX-like protein 2 [KO:K24155]
107737460  wdr7; WD repeat-containing protein 7 [KO:K24738]
107728123  nuclear receptor coactivator 7-like [KO:K25442]
107715985  oxidation resistance protein 1-like [KO:K25442]
107721058  oxidation resistance protein 1-like isoform X1 [KO:K25442]
107744356  lysosomal protective protein-like isoform X1 [KO:K13289] [EC:3.4.16.5]
107707902  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
107740260  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
107733172  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
107752788  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
107728112  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
107731820  dipeptidyl peptidase 1-like isoform X1 [KO:K01275] [EC:3.4.14.1]
107737423  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
107723590  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
107730483  cathepsin D isoform X1 [KO:K01379] [EC:3.4.23.5]
107748792  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
107740314  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
107725781  cathepsin E-like [KO:K01382] [EC:3.4.23.34]
107731709  cathepsin F-like [KO:K01373] [EC:3.4.22.41]
107758541  cathepsin F-like [KO:K01373] [EC:3.4.22.41]
107715232  ctsh; pro-cathepsin H [KO:K01366] [EC:3.4.22.16]
107717769  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
107741754  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
107755730  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
107727449  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
107731531  cathepsin L2-like [KO:K01365] [EC:3.4.22.15]
107726378  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
107711979  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
107715055  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
107721767  uncharacterized protein LOC107721767 [KO:K01365] [EC:3.4.22.15]
107727441  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
107744447  cathepsin L1-like isoform X1 [KO:K01365] [EC:3.4.22.15]
107740125  cathepsin O-like [KO:K01374] [EC:3.4.22.42]
107723788  LOW QUALITY PROTEIN: cathepsin O-like [KO:K01374] [EC:3.4.22.42]
107741752  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
107741753  cathepsin S-like isoform X1 [KO:K01368] [EC:3.4.22.27]
107741774  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
107714774  cathepsin L1-like [KO:K01368] [EC:3.4.22.27]
107708086  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
107750940  cathepsin Z-like isoform X1 [KO:K08568] [EC:3.4.18.1]
107729770  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
107732001  legumain-like [KO:K01369] [EC:3.4.22.34]
107705425  legumain-like [KO:K01369] [EC:3.4.22.34]
107739877  legumain-like [KO:K01369] [EC:3.4.22.34]
107719467  tripeptidyl-peptidase 1-like [KO:K01279] [EC:3.4.14.9]
107733161  tripeptidyl-peptidase 1-like [KO:K01279] [EC:3.4.14.9]
107740142  gla; alpha-galactosidase A [KO:K01189] [EC:3.2.1.22]
107746116  LOW QUALITY PROTEIN: beta-galactosidase-like [KO:K12309] [EC:3.2.1.23]
107725392  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
107722961  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
107758119  gaa; lysosomal alpha-glucosidase isoform X1 [KO:K12316] [EC:3.2.1.20]
107707168  glucosylceramidase-like [KO:K01201] [EC:3.2.1.45]
107743191  glucosylceramidase-like [KO:K01201] [EC:3.2.1.45]
107725121  idua; alpha-L-iduronidase [KO:K01217] [EC:3.2.1.76]
107750302  alpha-L-iduronidase-like [KO:K01217] [EC:3.2.1.76]
107758144  naga; alpha-N-acetylgalactosaminidase [KO:K01204] [EC:3.2.1.49]
107732063  alpha-N-acetylglucosaminidase-like isoform X1 [KO:K01205] [EC:3.2.1.50]
107718074  alpha-N-acetylglucosaminidase-like [KO:K01205] [EC:3.2.1.50]
107742352  galactocerebrosidase-like [KO:K01202] [EC:3.2.1.46]
107747942  galactocerebrosidase [KO:K01202] [EC:3.2.1.46]
107750876  galactocerebrosidase-like [KO:K01202] [EC:3.2.1.46]
107751776  galactocerebrosidase-like [KO:K01202] [EC:3.2.1.46]
107719352  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
107734369  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
107724286  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
107724287  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
107743818  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
107733546  fuca2; plasma alpha-L-fucosidase [KO:K01206] [EC:3.2.1.51]
107757500  beta-hexosaminidase subunit beta-like [KO:K12373] [EC:3.2.1.52]
107718643  beta-hexosaminidase subunit beta-like isoform X1 [KO:K12373] [EC:3.2.1.52]
107745438  beta-hexosaminidase subunit alpha-like isoform X1 [KO:K12373] [EC:3.2.1.52]
107747546  beta-mannosidase-like isoform X1 [KO:K01192] [EC:3.2.1.25]
107733670  beta-mannosidase-like [KO:K01192] [EC:3.2.1.25]
107737232  man2b1; lysosomal alpha-mannosidase [KO:K12311] [EC:3.2.1.24]
107751149  lysosomal alpha-mannosidase-like [KO:K12311] [EC:3.2.1.24]
107754787  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
107754788  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
107711305  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
107711321  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
107711968  hyaluronidase-1-like isoform X1 [KO:K01197] [EC:3.2.1.35]
107756016  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
107744379  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
107744380  LOW QUALITY PROTEIN: hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
107724516  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
107717507  hyaluronidase-2-like isoform X1 [KO:K01197] [EC:3.2.1.35]
107717524  hyaluronidase-3-like isoform X1 [KO:K01197] [EC:3.2.1.35]
107752304  hyaluronidase-4-like isoform X1 [KO:K01197] [EC:3.2.1.35]
107752305  hyaluronidase-like isoform X1 [KO:K01197] [EC:3.2.1.35]
107711933  hyaluronidase-3-like isoform X1 [KO:K01197] [EC:3.2.1.35]
107753633  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
107753713  hyaluronidase PH-20-like [KO:K01197] [EC:3.2.1.35]
107710387  arylsulfatase A-like [KO:K01134] [EC:3.1.6.8]
107719969  arsa; arylsulfatase A [KO:K01134] [EC:3.1.6.8]
107724712  arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
107734203  arylsulfatase G-like isoform X1 [KO:K12381] [EC:3.1.6.-]
107730157  galns; N-acetylgalactosamine-6-sulfatase [KO:K01132] [EC:3.1.6.4]
107728036  N-acetylgalactosamine-6-sulfatase-like [KO:K01132] [EC:3.1.6.4]
107708199  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
107726052  gns; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
107754550  iduronate 2-sulfatase-like [KO:K01136] [EC:3.1.6.13]
107742636  iduronate 2-sulfatase-like [KO:K01136] [EC:3.1.6.13]
107756031  N-sulphoglucosamine sulphohydrolase-like [KO:K01565] [EC:3.10.1.1]
107758444  lysosomal acid lipase/cholesteryl ester hydrolase-like isoform X1 [KO:K01052] [EC:3.1.1.13]
107753430  lysosomal acid lipase/cholesteryl ester hydrolase-like [KO:K01052] [EC:3.1.1.13]
107707506  group XV phospholipase A2-like [KO:K06129] [EC:3.1.1.5]
107714077  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
107726682  dnase2; deoxyribonuclease-2-alpha isoform X1 [KO:K01158] [EC:3.1.22.1]
107742910  dnase2b; LOW QUALITY PROTEIN: deoxyribonuclease-2-beta [KO:K01158] [EC:3.1.22.1]
107745346  deoxyribonuclease-2-beta-like [KO:K01158] [EC:3.1.22.1]
107722384  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
107742567  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
107712813  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
107713098  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
107706690  acp5; tartrate-resistant acid phosphatase type 5 isoform X1 [KO:K14379] [EC:3.1.3.2]
107718723  sphingomyelin phosphodiesterase-like [KO:K12350] [EC:3.1.4.12]
107720657  sphingomyelin phosphodiesterase-like [KO:K12350] [EC:3.1.4.12]
107707197  acid ceramidase-like isoform X1 [KO:K12348] [EC:3.5.1.23]
107747389  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
107721418  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
107757562  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
107740122  N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase- like isoform X1 [KO:K01444] [EC:3.5.1.26]
107725444  N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase- like [KO:K01444] [EC:3.5.1.26]
107723789  N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase- like [KO:K01444] [EC:3.5.1.26]
107717831  prosaposin-like isoform X1 [KO:K12382]
107754758  psap; prosaposin isoform X1 [KO:K12382]
107744174  prosaposin-like isoform X1 [KO:K12382]
107717390  ganglioside GM2 activator-like [KO:K12383]
107741090  ganglioside GM2 activator-like [KO:K12383]
107741106  ganglioside GM2 activator-like [KO:K12383]
107730851  lysosomal thioesterase PPT2-like [KO:K01074] [EC:3.1.2.22]
107758400  lysosomal thioesterase PPT2-A-like [KO:K01074] [EC:3.1.2.22]
107706207  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
107753389  ppt2; lysosomal thioesterase PPT2 [KO:K01074] [EC:3.1.2.22]
107752135  lysosomal thioesterase PPT2-like isoform X1 [KO:K01074] [EC:3.1.2.22]
107751063  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
107744542  lysosome-associated membrane glycoprotein 2-like isoform X1 [KO:K06528]
107756770  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
107748140  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
107747072  lamp1; lysosome-associated membrane glycoprotein 1 [KO:K06528]
107752011  lysosome-associated membrane glycoprotein 2-like isoform X1 [KO:K06528]
107747931  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
107752186  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
107731920  macrosialin-like isoform X1 [KO:K06501]
107738051  macrosialin-like isoform X1 [KO:K06501]
107756350  CD63 antigen-like [KO:K06497]
107723742  CD63 antigen-like [KO:K06497]
107720260  scarb2; lysosome membrane protein 2 isoform X1 [KO:K12384]
107717691  lysosome membrane protein 2-like [KO:K12384]
107756261  lysosome membrane protein 2-like [KO:K12384]
107752178  lysosome membrane protein 2-like [KO:K12384]
107752179  lysosome membrane protein 2-like [KO:K12384]
107735475  lysosome membrane protein 2-like [KO:K12384]
107708536  Niemann-Pick C1 protein-like [KO:K12385]
107747515  Niemann-Pick C1 protein-like isoform X1 [KO:K12385]
107731929  epididymal secretory protein E1 [KO:K13443]
107738274  epididymal secretory protein E1-like [KO:K13443]
107747199  cystinosin-like isoform X1 [KO:K12386]
107757929  cystinosin-like isoform X1 [KO:K12386]
107716316  sialin-like [KO:K12301]
107718830  sialin-like [KO:K12301]
107742862  sialin-like [KO:K12301]
107706204  sialin-like isoform X1 [KO:K12301]
107747835  natural resistance-associated macrophage protein 2-like [KO:K21398]
107724295  lysosomal-associated transmembrane protein 4B-like isoform X1 [KO:K12387]
107710576  lysosomal-associated transmembrane protein 4B-like [KO:K12387]
107743288  lysosomal-associated transmembrane protein 4A-like [KO:K12387]
107726758  lysosomal-associated transmembrane protein 4A-like [KO:K12387]
107730718  ATP-binding cassette sub-family A member 2-like isoform X1 [KO:K05642]
107744431  ATP-binding cassette sub-family A member 2-like [KO:K05642]
107709851  ATP-binding cassette sub-family B member 9-like [KO:K05656]
107721545  ATP-binding cassette sub-family B member 9-like [KO:K05656]
107726472  sialomucin core protein 24-like [KO:K06546]
107726625  sialomucin core protein 24-like [KO:K06546]
107747713  ectonucleoside triphosphate diphosphohydrolase 4-like isoform X1 [KO:K12305] [EC:3.6.1.6]
107710847  ectonucleoside triphosphate diphosphohydrolase 4-like isoform X1 [KO:K12305] [EC:3.6.1.6]
107715784  sortilin [KO:K12388]
107718224  sortilin-like [KO:K12388]
107731125  sortilin-like [KO:K12388]
107711994  sortilin-like [KO:K12388]
107738834  sortilin-like [KO:K12388]
107720039  battenin-like [KO:K12389]
107737814  battenin-like [KO:K12389]
107749021  ceroid-lipofuscinosis neuronal protein 5-like [KO:K12390]
107728242  ceroid-lipofuscinosis neuronal protein 5-like [KO:K12390]
107731658  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
107722537  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
107738985  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
107732668  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
107733463  mfsd8; major facilitator superfamily domain-containing protein 8 isoform X1 [KO:K12307]
107742491  hgsnat; heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
107726935  heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
107750043  heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
107710999  sumf1; sulfatase-modifying factor 1 [KO:K13444] [EC:1.8.3.7]
107725515  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
107725516  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
107744940  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
107717576  gnptg; N-acetylglucosamine-1-phosphotransferase subunit gamma isoform X1 [KO:K10087]
107747894  N-acetylglucosamine-1-phosphotransferase subunit gamma-like [KO:K10087]
107717356  N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like [KO:K01125] [EC:3.1.4.45]
107713811  N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like [KO:K01125] [EC:3.1.4.45]
107727636  cation-independent mannose-6-phosphate receptor-like [KO:K06564]
107743319  cation-independent mannose-6-phosphate receptor-like [KO:K06564]
107744715  cation-dependent mannose-6-phosphate receptor-like isoform X1 [KO:K10089]
107748841  cation-dependent mannose-6-phosphate receptor-like [KO:K10089]
107723183  clathrin light chain A-like isoform X1 [KO:K04644]
107758902  clathrin light chain A-like isoform X1 [KO:K04644]
107749760  clathrin light chain B-like isoform X1 [KO:K04645]
107750349  clathrin light chain B-like isoform X1 [KO:K04645]
107713425  clathrin heavy chain 1-like [KO:K04646]
107722848  clathrin heavy chain 1-like [KO:K04646]
107744621  clathrin heavy chain 1 isoform X1 [KO:K04646]
107747040  clathrin heavy chain 1-like [KO:K04646]
107754396  clathrin heavy chain 1-like isoform X1 [KO:K04646]
107738128  AP-1 complex subunit gamma-1-like isoform X1 [KO:K12391]
107738337  ap1g1; AP-1 complex subunit gamma-1 isoform X1 [KO:K12391]
107715458  AP-1 complex subunit gamma-1 isoform X1 [KO:K12391]
107706287  AP-1 complex subunit gamma-1-like [KO:K12391]
107730709  AP-1 complex subunit beta-1-like [KO:K12392]
107744474  AP-1 complex subunit beta-1-like [KO:K12392]
107705932  ap1m2; AP-1 complex subunit mu-2 [KO:K12393]
107724146  AP-1 complex subunit mu-1-like [KO:K12393]
107743903  AP-1 complex subunit mu-2-like [KO:K12393]
107750937  AP-1 complex subunit mu-1-like [KO:K12393]
107725189  AP-1 complex subunit mu-1-like [KO:K12393]
107754599  ap1m1; AP-1 complex subunit mu-1 [KO:K12393]
107706909  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12394]
107732206  AP-1 complex subunit sigma-2-like [KO:K12394]
107750569  ap1s1; AP-1 complex subunit sigma-1A isoform X1 [KO:K12394]
107752427  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12394]
107753894  AP-1 complex subunit sigma-2-like [KO:K12394]
107725117  AP-1 complex subunit sigma-3-like isoform X1 [KO:K12395]
107745619  AP-1 complex subunit sigma-3-like isoform X1 [KO:K12395]
107738797  AP-1 complex subunit sigma-3-like [KO:K12395]
107719554  ap3d1; AP-3 complex subunit delta-1 [KO:K12396]
107717992  AP-3 complex subunit delta-1-like [KO:K12396]
107720876  AP-3 complex subunit beta-1-like [KO:K12397]
107727587  ap3b2; AP-3 complex subunit beta-2 isoform X1 [KO:K12397]
107740194  AP-3 complex subunit beta-1-like isoform X1 [KO:K12397]
107738653  AP-3 complex subunit beta-2-like isoform X1 [KO:K12397]
107755857  AP-3 complex subunit mu-2 [KO:K12398]
107708250  AP-3 complex subunit mu-2-like [KO:K12398]
107743512  AP-3 complex subunit mu-1 isoform X1 [KO:K12398]
107726964  AP-3 complex subunit mu-1-like isoform X1 [KO:K12398]
107720511  AP-3 complex subunit sigma-2 [KO:K12399]
107729057  AP-3 complex subunit sigma-1-like isoform X1 [KO:K12399]
107728254  AP-3 complex subunit sigma-1 isoform X1 [KO:K12399]
107754348  ap4e1; AP-4 complex subunit epsilon-1 [KO:K12400]
107748318  AP-4 complex subunit epsilon-1-like [KO:K12400]
107746335  AP-4 complex subunit beta-1-like [KO:K12401]
107742404  AP-4 complex subunit mu-1-like [KO:K12402]
107720677  AP-4 complex subunit mu-1-like [KO:K12402]
107733114  AP-4 complex subunit sigma-1-like [KO:K12403]
107712552  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
107733910  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
107728183  LOW QUALITY PROTEIN: ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
107710174  ADP-ribosylation factor-binding protein GGA1-like isoform X1 [KO:K12404]
107751623  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
107751620  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
107755617  mucolipin-1-like [KO:K04992]
107712220  mucolipin-1-like [KO:K04992]
107718592  mucolipin-1-like [KO:K04992]
107716255  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
107725014  cell death-inducing p53-target protein 1-like isoform X1 [KO:K19363]
107709631  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
107709632  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
107745584  litaf; lipopolysaccharide-induced tumor necrosis factor-alpha factor [KO:K19363]
107730044  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
107724671  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
107727125  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
Compound
C00002  ATP
C00008  ADP
C00159  D-Mannose
C00275  D-Mannose 6-phosphate
Reference
PMID:12628346
  Authors
Eskelinen EL, Tanaka Y, Saftig P
  Title
At the acidic edge: emerging functions for lysosomal membrane proteins.
  Journal
Trends Cell Biol 13:137-45 (2003)
DOI:10.1016/S0962-8924(03)00005-9
Reference
PMID:1883197
  Authors
Neufeld EF
  Title
Lysosomal storage diseases.
  Journal
Annu Rev Biochem 60:257-80 (1991)
DOI:10.1146/annurev.bi.60.070191.001353
Reference
PMID:2943218
  Authors
von Figura K, Hasilik A
  Title
Lysosomal enzymes and their receptors.
  Journal
Annu Rev Biochem 55:167-93 (1986)
DOI:10.1146/annurev.bi.55.070186.001123
Reference
PMID:15987739
  Authors
Janvier K, Bonifacino JS
  Title
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins.
  Journal
Mol Biol Cell 16:4231-42 (2005)
DOI:10.1091/mbc.E05-03-0213
Reference
PMID:18635948
  Authors
Vergarajauregui S, Puertollano R
  Title
Mucolipidosis type IV: the importance of functional lysosomes for efficient autophagy.
  Journal
Autophagy 4:832-4 (2008)
DOI:10.4161/auto.6567
Reference
PMID:34249946
  Authors
Jaskolka MC, Winkley SR, Kane PM
  Title
RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification.
  Journal
Front Cell Dev Biol 9:698190 (2021)
DOI:10.3389/fcell.2021.698190
Reference
PMID:34646033
  Authors
Majdoul S, Compton AA
  Title
Lessons in self-defence: inhibition of virus entry by intrinsic immunity.
  Journal
Nat Rev Immunol 10.1038/s41577-021-00626-8 (2021)
DOI:10.1038/s41577-021-00626-8
Related
pathway
srx00511  Other glycan degradation
srx00531  Glycosaminoglycan degradation
srx04130  SNARE interactions in vesicular transport
srx04140  Autophagy - animal
srx04144  Endocytosis
KO pathway
ko04142   
LinkDB

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