KEGG   PATHWAY: pmei04070
Entry
pmei04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Poecilia mexicana (shortfin molly)
Class
Environmental Information Processing; Signal transduction
Pathway map
pmei04070  Phosphatidylinositol signaling system
pmei04070

Organism
Poecilia mexicana (shortfin molly) [GN:pmei]
Gene
106903481  [KO:K13084] [EC:3.1.3.78]
106903643  [KO:K13711] [EC:2.7.1.67]
106904013  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
106904437  [KO:K05860] [EC:3.1.4.11]
106904619  sacm1l; phosphatidylinositide phosphatase SAC1 isoform X1 [KO:K21797] [EC:3.1.3.-]
106904663  [KO:K05858] [EC:3.1.4.11]
106904775  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
106904799  [KO:K02183]
106905811  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
106906103  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
106906106  dgka; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
106906548  [KO:K00922] [EC:2.7.1.153]
106906613  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase [KO:K01099] [EC:3.1.3.36]
106906862  [KO:K05857] [EC:3.1.4.11]
106906975  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
106907915  [KO:K02649]
106908005  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
106908051  [KO:K04958]
106908122  [KO:K02649]
106908440  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
106908472  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
106908677  [KO:K13711] [EC:2.7.1.67]
106908830  [KO:K05857] [EC:3.1.4.11]
106909203  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
106909447  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
106909699  [KO:K02677] [EC:2.7.11.13]
106910271  [KO:K02649]
106910744  tmem55b; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
106911025  [KO:K19662] [EC:2.7.11.13]
106911454  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
106911596  [KO:K19801] [EC:2.7.1.67]
106911717  [KO:K00889] [EC:2.7.1.68]
106911768  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
106911965  [KO:K21797] [EC:3.1.3.-]
106912688  [KO:K01092] [EC:3.1.3.25]
106912812  impa1; inositol monophosphatase 1 isoform X1 [KO:K01092] [EC:3.1.3.25]
106913919  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
106914299  dgkd; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
106914598  [KO:K13084] [EC:3.1.3.78]
106914699  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
106915220  prkcb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
106915291  ocrl; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
106915761  [KO:K01106] [EC:3.1.3.56]
106916046  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
106916277  [KO:K00889] [EC:2.7.1.68]
106916309  plcd4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
106917017  [KO:K00901] [EC:2.7.1.107]
106917051  [KO:K02649]
106917126  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
106917253  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
106917254  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
106917640  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
106917759  [KO:K00889] [EC:2.7.1.68]
106918251  itpka; inositol-trisphosphate 3-kinase A isoform X1 [KO:K00911] [EC:2.7.1.127]
106918621  tmem55a; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
106918954  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
106919021  [KO:K02649]
106919104  [KO:K01116] [EC:3.1.4.11]
106919435  [KO:K00901] [EC:2.7.1.107]
106919753  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
106919961  [KO:K00889] [EC:2.7.1.68]
106920554  [KO:K01109] [EC:3.1.3.66]
106920607  [KO:K00922] [EC:2.7.1.153]
106920725  pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
106920945  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
106921031  plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
106921104  calml4; calmodulin-like protein 4 [KO:K02183]
106921292  [KO:K00889] [EC:2.7.1.68]
106921414  [KO:K01092] [EC:3.1.3.25]
106921942  dgkz; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
106922170  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
106922331  [KO:K00981] [EC:2.7.7.41]
106922880  dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
106922942  [KO:K02183]
106923190  [KO:K00911] [EC:2.7.1.127]
106923219  [KO:K07756] [EC:2.7.4.21]
106923268  [KO:K00920] [EC:2.7.1.149]
106923726  inpp5e; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
106924234  prkca; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
106924563  [KO:K13024] [EC:2.7.4.24]
106924570  [KO:K01106] [EC:3.1.3.56]
106926118  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
106926194  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
106926316  [KO:K00889] [EC:2.7.1.68]
106926608  pi4ka; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
106926707  [KO:K01109] [EC:3.1.3.66]
106926721  [KO:K15909] [EC:3.1.3.86]
106926785  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
106926826  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
106926941  [KO:K00901] [EC:2.7.1.107]
106926956  [KO:K05857] [EC:3.1.4.11]
106927213  ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
106927347  plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
106927446  [KO:K00981] [EC:2.7.7.41]
106927594  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
106927825  inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
106927943  [KO:K13024] [EC:2.7.4.24]
106928494  itpk1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
106928511  [KO:K05857] [EC:3.1.4.11]
106928883  [KO:K02649]
106928904  inpp4a; type I inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
106928990  [KO:K00922] [EC:2.7.1.153]
106929121  pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
106929241  [KO:K05861] [EC:3.1.4.11]
106929282  [KO:K05858] [EC:3.1.4.11]
106929299  [KO:K00888] [EC:2.7.1.67]
106929319  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
106929786  ip6k2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
106930120  [KO:K00911] [EC:2.7.1.127]
106930415  calm2; calmodulin [KO:K02183]
106930552  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
106930983  mtmr7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
106931041  [KO:K19663] [EC:2.7.11.13]
106931303  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
106931409  impad1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
106931423  itpkc; inositol-trisphosphate 3-kinase C isoform X1 [KO:K00911] [EC:2.7.1.127]
106931665  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
106932178  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
106932289  itpr1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
106932299  dgke; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
106932431  pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
106933237  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
106933653  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
106934232  [KO:K19801] [EC:2.7.1.67]
106934245  calm3; calmodulin [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
pmei04020  Calcium signaling pathway
pmei04144  Endocytosis
pmei04510  Focal adhesion
KO pathway
ko04070   

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