KEGG   PATHWAY: pmur04070
Entry
pmur04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Protobothrops mucrosquamatus (Taiwan habu)
Class
Environmental Information Processing; Signal transduction
Pathway map
pmur04070  Phosphatidylinositol signaling system
pmur04070

Organism
Protobothrops mucrosquamatus (Taiwan habu) [GN:pmur]
Gene
107282273  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
107282442  [KO:K19663] [EC:2.7.11.13]
107282725  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
107282850  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [KO:K00889] [EC:2.7.1.68]
107282916  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
107283186  DGKH; LOW QUALITY PROTEIN: diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
107283409  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
107283596  [KO:K02649]
107283636  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
107283902  CALML4; calmodulin-like protein 4 [KO:K02183]
107284364  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [KO:K05857] [EC:3.1.4.11]
107284997  [KO:K00922] [EC:2.7.1.153]
107285104  PRKCB; protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
107285107  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
107285111  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
107285365  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
107285366  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [KO:K05858] [EC:3.1.4.11]
107285511  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
107285512  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
107285647  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
107285699  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
107285754  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
107285879  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
107286152  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
107286153  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
107286221  [KO:K05858] [EC:3.1.4.11]
107286281  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [KO:K05857] [EC:3.1.4.11]
107286404  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
107287061  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
107287062  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
107287257  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
107287775  DGKA; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
107287851  CALM2; calmodulin-2 [KO:K02183]
107288141  [KO:K19663] [EC:2.7.11.13]
107288186  [KO:K00901] [EC:2.7.1.107]
107288410  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
107288553  INPP4B; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
107288560  MTMR4; myotubularin-related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
107288588  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
107288593  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
107288596  INPP5F; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
107288788  MTMR3; myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
107289186  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
107289795  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 [KO:K13024] [EC:2.7.4.24]
107290594  SYNJ1; synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
107290686  CALML6; calmodulin-like protein 6 [KO:K02183]
107290817  [KO:K05858] [EC:3.1.4.11]
107290924  MTMR14; myotubularin-related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
107291207  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
107291279  [KO:K00999] [EC:2.7.8.11]
107291489  PLCD4; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
107291571  OCRL; inositol polyphosphate 5-phosphatase OCRL-1 [KO:K01099] [EC:3.1.3.36]
107291850  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
107291942  CALM3; calmodulin-3 [KO:K02183]
107292043  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
107292046  [KO:K01108] [EC:3.1.3.64 3.1.3.95]
107292269  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
107292313  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
107292340  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
107292392  CALM1; calmodulin-1 [KO:K02183]
107292429  [KO:K02183]
107292592  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 [KO:K13024] [EC:2.7.4.24]
107292601  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
107293193  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
107293333  PI4KA; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
107293430  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
107293540  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
107293545  [KO:K05861] [EC:3.1.4.11]
107293546  [KO:K05861] [EC:3.1.4.11]
107293737  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
107293785  SACM1L; phosphatidylinositide phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
107294179  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
107294420  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
107294724  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
107294909  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
107295218  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
107295225  MTMR2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
107295459  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
107295460  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
107295575  [KO:K00889] [EC:2.7.1.68]
107295582  PI4KB; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
107296042  [KO:K00920] [EC:2.7.1.149]
107296233  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
107296465  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
107296516  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
107297343  SYNJ2; synaptojanin-2 [KO:K20279] [EC:3.1.3.36]
107297355  [KO:K02183]
107297770  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
107298309  [KO:K19801] [EC:2.7.1.67]
107298464  [KO:K00923] [EC:2.7.1.154]
107298510  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
107298963  [KO:K00911] [EC:2.7.1.127]
107298984  [KO:K01116] [EC:3.1.4.11]
107299064  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
107300082  [KO:K00888] [EC:2.7.1.67]
107300554  IMPAD1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
107300809  [KO:K01107] [EC:3.1.3.57]
107301415  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
107301493  [KO:K01092] [EC:3.1.3.25]
107301803  MTMR7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
107302156  [KO:K02183]
107302905  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
107302983  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
107303189  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
107303203  [KO:K00901] [EC:2.7.1.107]
114923392  [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
pmur04020  Calcium signaling pathway
pmur04144  Endocytosis
pmur04510  Focal adhesion
KO pathway
ko04070   

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