KEGG   PATHWAY: ppug04070
Entry
ppug04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Pungitius pungitius (ninespine stickleback)
Class
Environmental Information Processing; Signal transduction
Pathway map
ppug04070  Phosphatidylinositol signaling system
ppug04070

Organism
Pungitius pungitius (ninespine stickleback) [GN:ppug]
Gene
119193940  dgkab; diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
119193950  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
119194071  [KO:K07756] [EC:2.7.4.21]
119194315  [KO:K04958]
119194530  [KO:K05858] [EC:3.1.4.11]
119194531  plcb1l; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
119194812  [KO:K02183]
119195151  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
119195503  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
119196016  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
119196036  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
119196169  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X2 [KO:K13024] [EC:2.7.4.24]
119196180  [KO:K05861] [EC:3.1.4.11]
119196688  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
119196715  calml4b; calmodulin-like protein 4 [KO:K02183]
119196721  pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
119197105  [KO:K00889] [EC:2.7.1.68]
119197117  [KO:K00901] [EC:2.7.1.107]
119197346  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X2 [KO:K01099] [EC:3.1.3.36]
119197679  sacm1lb; phosphatidylinositol-3-phosphatase SAC1-B [KO:K21797] [EC:3.1.3.-]
119197969  pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
119197992  dgkb; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
119198242  prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
119198356  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
119198457  [KO:K01092] [EC:3.1.3.25]
119198458  [KO:K01092] [EC:3.1.3.25]
119198727  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
119198874  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
119207320  pip4p1a; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A [KO:K13084] [EC:3.1.3.78]
119209064  [KO:K05857] [EC:3.1.4.11]
119209104  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
119209283  bpnt2; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
119209321  [KO:K00922] [EC:2.7.1.153]
119209332  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
119209420  [KO:K02649]
119209545  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
119209634  [KO:K00889] [EC:2.7.1.68]
119210409  ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
119210463  inppl1b; inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
119210896  [KO:K00901] [EC:2.7.1.107]
119211232  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
119211256  mtmr7a; myotubularin-related protein 7a [KO:K18083] [EC:3.1.3.64 3.1.3.95]
119212017  calm3a; calmodulin 3a (phosphorylase kinase, delta) [KO:K02183]
119212734  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
119212786  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
119212840  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
119213036  [KO:K05857] [EC:3.1.4.11]
119213100  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
119213835  [KO:K01106] [EC:3.1.3.56]
119213849  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
119214039  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
119214056  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
119214113  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
119214401  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
119215059  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
119215062  mtmr4; myotubularin-related protein 4 isoform X2 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
119215371  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
119215569  itpkca; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
119216237  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
119216496  [KO:K01116] [EC:3.1.4.11]
119216917  [KO:K02649]
119216976  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
119216981  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
119217019  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
119217096  [KO:K00922] [EC:2.7.1.153]
119217140  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
119217370  [KO:K19662] [EC:2.7.11.13]
119217424  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
119217675  mtmr7b; myotubularin-related protein 7b isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
119217725  pi4k2b; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
119218179  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
119218445  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
119218609  prkcaa; protein kinase C, alpha, a isoform X1 [KO:K02677] [EC:2.7.11.13]
119218646  [KO:K00920] [EC:2.7.1.149]
119218766  sacm1la; phosphatidylinositol-3-phosphatase SAC1-A [KO:K21797] [EC:3.1.3.-]
119218767  [KO:K00889] [EC:2.7.1.68]
119218932  [KO:K19801] [EC:2.7.1.67]
119219033  [KO:K00901] [EC:2.7.1.107]
119219199  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
119219745  [KO:K01109] [EC:3.1.3.66]
119220222  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
119220489  [KO:K05857] [EC:3.1.4.11]
119220528  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
119222111  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
119222436  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
119222463  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
119222464  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
119222668  dgkaa; LOW QUALITY PROTEIN: diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
119222704  [KO:K00922] [EC:2.7.1.153]
119222835  itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X3 [KO:K04960]
119222873  si:dkey-172j4.3; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
119223022  [KO:K13084] [EC:3.1.3.78]
119223188  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
119223301  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
119223355  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
119224457  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b isoform X1 [KO:K00888] [EC:2.7.1.67]
119224521  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
119224577  inpp5l; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
119224672  [KO:K02649]
119224767  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
119224849  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
119225382  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
119225529  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
119226302  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
119226352  pi4kaa; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
119227103  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a isoform X1 [KO:K00889] [EC:2.7.1.68]
119227175  itpk1b; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
119227178  calm1a; calmodulin-1a [KO:K02183]
119227921  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
119227944  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
119228408  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
119228516  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2 [KO:K05857] [EC:3.1.4.11]
119228522  dgkh; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
119228786  [KO:K00901] [EC:2.7.1.107]
119228827  ppip5k1a; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
119228978  inpp4aa; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
119229258  calml4a; calmodulin-like protein 4a [KO:K02183]
119229493  itpr1b; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
119229602  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
119229705  ippk; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
119229781  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
119229977  [KO:K00920] [EC:2.7.1.149]
119230007  [KO:K07756] [EC:2.7.4.21]
119230140  mtmr14; myotubularin-related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
ppug04020  Calcium signaling pathway
ppug04144  Endocytosis
ppug04510  Focal adhesion
KO pathway
ko04070   

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