KEGG   PATHWAY: xco04070
Entry
xco04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Xiphophorus couchianus (Monterrey platyfish)
Class
Environmental Information Processing; Signal transduction
Pathway map
xco04070  Phosphatidylinositol signaling system
xco04070

Organism
Xiphophorus couchianus (Monterrey platyfish) [GN:xco]
Gene
114133153  inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
114133784  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
114133945  itpk1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
114133997  itpka; inositol-trisphosphate 3-kinase A isoform X1 [KO:K00911] [EC:2.7.1.127]
114134100  [KO:K02183]
114134877  [KO:K00920] [EC:2.7.1.149]
114135172  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
114135479  [KO:K04958]
114135665  [KO:K07756] [EC:2.7.4.21]
114135727  [KO:K07756] [EC:2.7.4.21]
114135867  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
114135879  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
114135884  [KO:K07756] [EC:2.7.4.21]
114136057  ippk; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
114136183  itpr1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
114136265  [KO:K07756] [EC:2.7.4.21]
114136282  [KO:K00901] [EC:2.7.1.107]
114136625  plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
114136696  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
114136794  [KO:K01092] [EC:3.1.3.25]
114136796  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
114137026  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
114137117  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
114137818  inpp5a; type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01106] [EC:3.1.3.56]
114138153  calm2; calmodulin-2 [KO:K02183]
114138179  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
114138347  [KO:K05858] [EC:3.1.4.11]
114138529  inpp5f; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
114139229  ocrl; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
114139276  dgkq; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
114139291  mtmr7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
114139388  [KO:K15909] [EC:3.1.3.86]
114139403  [KO:K00911] [EC:2.7.1.127]
114140407  [KO:K00901] [EC:2.7.1.107]
114140496  pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
114140753  [KO:K01109] [EC:3.1.3.66]
114141097  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
114141237  [KO:K05857] [EC:3.1.4.11]
114141391  [KO:K02649]
114141588  [KO:K19801] [EC:2.7.1.67]
114141819  [KO:K00889] [EC:2.7.1.68]
114141914  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
114141948  [KO:K19663] [EC:2.7.11.13]
114142168  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
114143062  calml4; calmodulin-like protein 4 [KO:K02183]
114143533  ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
114143861  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
114144259  prkca; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
114144293  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
114144322  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
114144473  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
114144576  [KO:K02649]
114144631  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
114144651  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
114144935  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
114145501  [KO:K19662] [EC:2.7.11.13]
114145811  pip4p1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
114145908  [KO:K02649]
114146103  [KO:K02649]
114146196  [KO:K01092] [EC:3.1.3.25]
114146717  impad1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
114146742  [KO:K05857] [EC:3.1.4.11]
114146763  [KO:K00922] [EC:2.7.1.153]
114146805  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
114147080  [KO:K00889] [EC:2.7.1.68]
114147594  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
114147790  plcd4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
114148411  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
114148418  dgkg; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
114149262  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
114149407  [KO:K00888] [EC:2.7.1.67]
114149780  [KO:K00889] [EC:2.7.1.68]
114150512  [KO:K13024] [EC:2.7.4.24]
114150541  [KO:K00922] [EC:2.7.1.153]
114150593  [KO:K05857] [EC:3.1.4.11]
114150599  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
114150685  [KO:K02649]
114150691  ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
114150850  pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
114151085  [KO:K01116] [EC:3.1.4.11]
114151307  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
114152048  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
114152870  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
114152924  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
114153029  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
114153110  [KO:K21797] [EC:3.1.3.-]
114154163  [KO:K00981] [EC:2.7.7.41]
114154184  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
114154214  [KO:K00889] [EC:2.7.1.68]
114154527  [KO:K00888] [EC:2.7.1.67]
114154562  [KO:K00981] [EC:2.7.7.41]
114154692  [KO:K01106] [EC:3.1.3.56]
114155114  inpp5e; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
114155681  [KO:K21797] [EC:3.1.3.-]
114156427  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
114156502  pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
114156619  [KO:K00889] [EC:2.7.1.68]
114157035  [KO:K00922] [EC:2.7.1.153]
114157038  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
114157059  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
114157060  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
114157212  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
114157271  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
114157398  [KO:K00901] [EC:2.7.1.107]
114157441  [KO:K05858] [EC:3.1.4.11]
114157811  [KO:K13084] [EC:3.1.3.78]
114157947  dgkz; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
114158311  calm1; calmodulin-1 [KO:K02183]
114158603  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
114158604  plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
114158655  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
114159570  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
114159765  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
114159779  [KO:K05861] [EC:3.1.4.11]
114159851  [KO:K02677] [EC:2.7.11.13]
114159895  prkcb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
114160100  [KO:K05857] [EC:3.1.4.11]
114160924  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
114161563  calm3; calmodulin-3 [KO:K02183]
114161667  itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
114161702  dgkd; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
114161826  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
xco04020  Calcium signaling pathway
xco04144  Endocytosis
xco04510  Focal adhesion
KO pathway
ko04070   

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