KEGG MEDICUS 疾患情報 |
Top |
| エントリ | 名称 | 概要 | カテゴリ | パスウェイ | 病因遺伝子 |
|---|---|---|---|---|---|
| H01445 |
尋常性座瘡 にきび |
Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production, altered keratinization, inflammation, and bacterial colonization of hair follicles ... | 細菌感染症 | ||
| H01446 | Propionibacterium acnes 感染 | The anaerobic Gram-positive bacterium Propionibacterium acnes which forms part of the normal resident human microbiota of the skin, oral cavity, and gastrointestinal and genitourinary tracts. The organism ... | 細菌感染症 | ||
| H01447 | 身体醜形障害 | Body dysmorphic disorder (BDD) is a psychiatric disorder in which individuals are preoccupied with imagined defects in their appearance, which are not noticeable or appear slight to others. It is characterized ... | 精神及び行動の障害 | ||
| H01448 | 溜め込み障害 | Hoarding disorder is characterized by persistent difficulty discarding possessions, regardless of the value others may attribute to these possessions. They accumulate a large number of possessions that ... | 精神及び行動の障害 | ||
| H01449 | 皮膚引っ掻き症 | Excoriation Disorder, also known as Skin Picking Disorder, is characterized by the repetitive and compulsive scratching or picking of skin, which causes tissue damage. Patients spend a significant amount ... | 精神及び行動の障害 | ||
| H01450 | 強迫性障害 | Obsessive-compulsive disorder (OCD) is a psychiatric disorder characterized by recurrent, intrusive and disturbing thoughts as well as by repetitive stereotypic behaviors. OCD is a complex disorder and ... | 精神及び行動の障害 |
HTR2A [HSA:3356] [KO:K04157] SLC6A4 [HSA:6532] [KO:K05037] |
|
| H01451 | 放線菌腫 | Mycetoma is an infectious disease of skin and subcutaneous tissue. It can be caused by either bacteria (actinomycetoma) or fungi (eumycetoma [DS:H02385] ). It is endemic in tropical and subtropical regions ... | 細菌感染症 | ||
| H01452 | レンサ球菌感染性小児自己免疫神経精神障害 | Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS) is an autoimmune disorder presenting with obsessive compulsive disorder (OCD) and/or tics. PANDAS is believed ... | 免疫系疾患 | ||
| H01453 | 強迫性障害および関連障害群 | Obsessive-Compulsive and Related Disorder (OCRD) is a group of disorders that is characterized by having preoccupations (obsessions) and/or repetitive behaviors (compulsions). Previously, Obsessive-compulsive ... | 精神及び行動の障害 | ||
| H01454 | 結腸スピロヘータ症 | Colonic spirochetosis (CS) is a disease caused by the Brachyspira genus, Brachyspira aalborgi and Brachyspira pilosicoli. B. pilosicoli induces disease in both humans and animals, whereas B. aalborgi affects ... | 細菌感染症 | ||
| H01455 | 壊死性筋膜炎 | Necrotizing fasciitis (NF) is a severe life-threatening soft tissue infection characterized by rapidly spreading necrosis of the fascia and the subcutaneous tissue. Although more common in adults, NF also ... | 細菌感染症 | ||
| H01456 | 糖尿病性腎症 | Diabetic nephropathy (DN), also called diabetic kidney disease, is a microvascular complication of diabetes that induces dysfunction in various cell types of the kidney, ultimately leading to renal failure ... | 内分泌代謝疾患; 泌尿器系疾患 |
(Type 1 DN) VEGFA [HSA:7422] [KO:K05448] (Type 1,2 DN) ACE [HSA:1636] [KO:K01283] (Type 1,2 DN) SOD2 [HSA:6648] [KO:K04564] |
|
| H01457 | 糖尿病性網膜症 | Diabetic retinopathy (DR), one of the most common vascular complication of diabetes, is the leading cause of visual deficits and blindness around the world. The development of DR is divided into two stages: ... | 内分泌代謝疾患; 神経系疾患 |
VEGFA [HSA:7422] [KO:K05448] EPO [HSA:2056] [KO:K05437] ACE [HSA:1636] [KO:K01283] PON1 [HSA:5444] [KO:K01045] |
|
| H01458 |
非結核性抗酸菌症 非定型抗酸菌症 |
Mycobacteria species other than the obligate pathogens Mycobacterium tuberculosis complex and Mycobacterium leprae are known as nontuberculous mycobacteria (NTM) or atypical mycobacteria. NTM are normal ... | 細菌感染症 | ||
| H01459 | 糖尿病性神経障害 | Diabetic neuropathies (DNs) are nerve-damaging disorders caused by diabetes. Diabetic neuropathy broadly comprises generalized symmetric polyneuropathies (acute sensory, chronic sensorimotor, autonomic) ... | 内分泌代謝疾患; 神経系疾患 | VEGFA (polymorphism) [HSA:7422] [KO:K05448] | |
| H01460 |
ウエスト症候群 点頭てんかん |
West syndrome, or infantile spasms (IS), is an infantile epileptic encephalopathy characterized by at least two of the following features: (a) clusters of flexion or extension epileptic spasms, (b) interictal ... | 神経系疾患 | ARX [HSA:170302] [KO:K09452] | |
| H01461 |
クロウ・深瀬症候群 POEMS 症候群 |
Crow-Fukase syndrome, also called POEMS syndrome, is a rare paraneoplastic syndrome due to an underlying plasma cell neoplasm, characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal ... | 新生物 | ||
| H01462 | Rapidly growing mycobacteria 感染症 | Nontuberculous mycobacteria (NTM) are classified into 2 categories: slow-growing mycobacteria (SGM) and rapidly-growing mycobacteria (RGM), based on interval to colony formation by subculture on solid ... | 細菌感染症 | ||
| H01463 | 菌状息肉腫 | Mycosis fungoides (MF) is the most common type of primary cutaneous T-cell lymphomas (CTCL), which are a heterogeneous group of malignancies derived from skin-homing T cells. MF presents in the skin with ... | がん |
p16/INK4a, ARF (mutation,deletion) [HSA:1029] [KO:K06621] p15/INK4b (mutation, deletion) [HSA:1030] [KO:K04685] PTEN (mutation) [HSA:5728] [KO:K01110] p53 (mutation) [HSA:7157] [KO:K04451] JUNB (mutation) [HSA:3726] [KO:K09028] Fas (loss of expression) [HSA:355] [KO:K04390] Nav3 (deletion) [HSA:89795] [KO:K23919] c-MYC (amplification) [HSA:4609] [KO:K04377] |
|
| H01464 | マントル細胞リンパ腫 | Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma (NHL) and it accounts for about 6% of all NHL cases. Diagnosis is based on lymph node, bone marrow, or tissue morphology of centrocytic lymphocytes ... | がん |
Cyclin D1 (overexpression) [HSA:595] [KO:K04503] p16/INK4a (deletion) [HSA:1029] [KO:K06621] p53 (mutation) [HSA:7157] [KO:K04451] |
|
| H01465 | 大型血管炎 | Large vessel vasculitis (LVV) covers a spectrum of primary vasculitides predominantly affecting the aorta and its major branches. Giant cell arteritis (GCA) and Takayasu arteritis (TAK) are the two main ... | 免疫系疾患 | ||
| H01466 | 潰瘍性大腸炎 | Ulcerative colitis (UC) is one subtype of inflammatory bowel disease (IBD) whose pathogenesis is multifactorial and includes influences from genes, the environment, and the gut microbiome. In UC the inflammatory ... | 免疫系疾患 |
IL23R [HSA:149233] [KO:K05065] IL10 [HSA:3586] [KO:K05443] IL37 [HSA:27178] [KO:K05485] MST1 [HSA:4485] [KO:K23441] |
|
| H01467 |
原発性胆汁性胆管炎 原発性胆汁性肝硬変 |
Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic, progressive cholestatic liver disease characterised by destruction of small intrahepatic bile ducts, eventually ... | 消化器系疾患 | ||
| H01468 |
好酸球性多発血管炎性肉芽腫症 チャーグストラウス症候群 |
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitic disorder of unknown etiology that affects small-to-medium-size blood vessels. This disease has been called Churg-Strauss syndrome ... | 免疫系疾患 | ||
| H01469 | 短腸症候群 | Short bowel syndrome (SBS), also called short gut syndrome or simply short gut, is a malabsorption disorder. It typically occurs in people who lost at least half of their small intestine due to surgical ... | 消化器系疾患 | ||
| H01470 | 骨巨細胞腫 | Giant-cell tumor of bone (GCTB) is a rare osteolytic tumor of the bone. Although classified as a benign tumor, GCTB is characterized by local aggressiveness and risk of local recurrence. Its name is derived ... | がん |
RANKL (overexpression) [HSA:8600] [KO:K05473] H3F3A (mutation) [HSA:3020] [KO:K11253] TP53 (mutation) [HSA:7157] [KO:K04451] HRAS (mutation) [HSA:3265] [KO:K02833] |
|
| H01471 | リンパ管腫 | Lymphangiomas are congenital malformations of the lymphatic system, which is located mostly on the head and neck region. The lesions consist of dilated endothelium-lined spaces that vary in size from microscopic ... | 新生物 | VEGFR-3 (overexpression) [HSA:2324] [KO:K05097] | |
| H01472 | 多剤耐性結核 | Multi-drug-resistant tuberculosis is generally defined as infection with M. tuberculosis strains that are resistant to isoniazid and rifampin, the first-line antibiotics for treating tuberculosis. Drug-resistant ... | 細菌感染症 | ||
| H01473 | らい性結節性紅斑 | Reactional states of leprosy are expressions of immunological disturbance and are generally divided into two variants: type 1 (Jopling's type I or reversal reaction) and type 2 (Jopling's type II reaction) ... | 細菌感染症 | ||
| H01474 |
後天性全身性脂肪萎縮症 Lawrence 症候群 |
Acquired generalized lipodystrophy (AGL), also called the Lawrence syndrome, is one subtype of acquired lipodystrophy caused by autoimmune disease, panniculitis or idiopathic. The disorder appears during ... | 先天性代謝異常症 |