Entry |
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Name |
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Definition |
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Pathway |
ko00140 | Steroid hormone biosynthesis |
ko04917 | Prolactin signaling pathway |
ko04927 | Cortisol synthesis and secretion |
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Module |
M00109 | C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone |
M00110 | C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone |
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Disease |
H00216 | Congenital adrenal hyperplasia |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
04917 Prolactin signaling pathway
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
04927 Cortisol synthesis and secretion
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.19 steroid 17alpha-monooxygenase
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
CYP17 family
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Chung BC, Picado-Leonard J, Haniu M, Bienkowski M, Hall PF, Shively JE, Miller WL |
Title |
Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues. |
Journal |
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Sequence |
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Reference |
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Authors |
Zhou LY, Wang DS, Kobayashi T, Yano A, Paul-Prasanth B, Suzuki A, Sakai F, Nagahama Y |
Title |
A novel type of P450c17 lacking the lyase activity is responsible for C21-steroid biosynthesis in the fish ovary and head kidney. |
Journal |
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Sequence |
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LinkDB |
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