KEGG   ORTHOLOGY: K13285
Entry
K13285                      KO                                     
Symbol
sipB, ipaB, bipB
Name
invasin B
Pathway
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
nt06139  NLR signaling (viruses and bacteria)
  Element
N00949  Shigella IpaB to NLRC4 Inflammasome signaling pathway
N01081  Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway
N01126  Salmonella SipB to Inflammasome signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K13285  sipB, ipaB, bipB; invasin B
   05131 Shigellosis
    K13285  sipB, ipaB, bipB; invasin B
   05100 Bacterial invasion of epithelial cells
    K13285  sipB, ipaB, bipB; invasin B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K13285  sipB, ipaB, bipB; invasin B
Transporters [BR:ko02000]
 Other transporters
  Pores ion channels
   K13285  sipB, ipaB, bipB; invasin B
Other DBs
TC: 1.C.36.3
Genes
ECM: EcSMS35_4020
EUM: ECUMN_4182
ECT: ECIAI39_4254
EOC: CE10_4294(sipB)
ELO: EC042_4008
EAL: EAKF1_ch2273c
EMA: C1192_24310
STY: STY3008(sipB)
STT: t2787(sipB)
SEX: STBHUCCB_29310
STM: STM2885(sipB)
SEO: STM14_3484(sipB)
SEY: SL1344_2864(sipB)
SEJ: STMUK_2874(sipB)
SEB: STM474_3024(sipB)
SEF: UMN798_3133(sipB)
SENR: STMDT2_27841(sipB)
SEND: DT104_28821(sipB)
SENI: CY43_15065
SPT: SPA2743(sipB)
SEK: SSPA2557
SEI: SPC_2927(sipB)
SEC: SCH_2817(sipB)
SHB: SU5_03366
SENS: Q786_13885
SED: SeD_A3195
SEG: SG2787(sipB)
SEL: SPUL_2882(sipB)
SEGA: SPUCDC_2868(sipB)
SET: SEN2726(sipB)
SENA: AU38_13845
SENO: AU37_13855
SENV: AU39_13855
SENQ: AU40_15600
SENL: IY59_14445
SEEP: I137_13735
SENE: IA1_13800
SBG: SBG_2505(sipB)
SBZ: A464_2909
SFL: CP0128(ipaB)
SFE: SFxv_4971(ipaB)
SSN: SSON_P090(ipaB)
SDY: SDY_P166(ipaB)
HDE: HDEF_1511(sipB)
SYM: K6K13_16235(sctE) K6K13_18815(sctE)
YRE: HEC60_07295(sctE) HEC60_24990(sctE)
YEN: YE3537(yspB)
YEW: CH47_80
YAL: AT01_1832
YRU: BD65_2679
RBAD: H2866_16690(sctE)
PPAV: LOZ86_18880(sctE)
SGL: SG0574
SOD: Sant_3183(yspB)
EAM: EAMY_0790(sipB1) EAMY_1591(sipB3)
ETA: ETA_18960(sipB1) ETA_26820(sipB2)
EPY: EpC_19830(sipB)
EPR: EPYR_02141(sipB)
ERJ: EJP617_27360(sipB)
ETP: LU633_00965(sctE)
PSTW: DSJ_24165
PMR: PMI2683
PHAU: PH4a_04955
PPEE: I6G31_11715(sctE)
PSI: S70_09760
PSX: DR96_1233
PRG: RB151_002100(sipB)
PHEI: NCTC12003_00209(sipB)
PRJ: NCTC6933_00199(sipB)
MMK: MU9_22
ANS: ArsFIN_03170(ipaB) ArsFIN_08880(sipB)
AET: LDL57_02880(sctE)
XAL: XALC_1504(xipB)
XPH: XppCFBP6546_12470(sctE)
PFE: PSF113_1790(sipB)
PPUU: PputUW4_03623(sipB)
PUM: HGP31_22705(sctE)
PVW: HU752_024780(sctE)
PAZE: KSS91_08890(sctE)
PZA: HU749_010155(sctE)
CVI: CV_2619(sipB)
CHAE: CH06BL_42050(cipB)
BMA: BMAA1531(bipB)
BML: BMA10229_2071(bipB)
BMN: BMA10247_A0753(bipB)
BMAL: DM55_4863(bipB)
BMAE: DM78_4109(bipB)
BMAQ: DM76_3816(bipB)
BMAI: DM57_08295
BMAF: DM51_3237(bipB)
BMAZ: BM44_4992(bipB)
BMAB: BM45_3893(bipB)
BPS: BPSS1532(bipB)
BPM: BURPS1710b_A0571(bipB)
BPL: BURPS1106A_A2074(bipB)
BPSE: BDL_4841(bipB)
BPSM: BBQ_4618(bipB)
BPSU: BBN_4976(bipB)
BPSD: BBX_4003(bipB)
BPZ: BP1026B_II1628(bipB)
BPK: BBK_4141
BPSH: DR55_3744(bipB)
BPSA: BBU_4503(bipB)
BPSO: X996_3530(bipB)
BUT: X994_5585(bipB)
BTQ: BTQ_4128(bipB)
BTJ: BTJ_5160(bipB)
BTZ: BTL_3631(bipB)
BTD: BTI_4011(bipB)
BTV: BTHA_4257(bipB)
BTHE: BTN_5614(bipB)
BTHM: BTRA_3622(bipB)
BTHA: DR62_3380
BTHL: BG87_3584(bipB)
BOK: DM82_5839(bipB)
BOC: BG90_4792(bipB)
BDL: AK34_4706
BCON: NL30_37135
BUL: BW21_6005(bipB)
PPNO: DA70_15445
PPNM: LV28_15235
PSPU: NA29_05190
GLC: JQN73_18885(sctE)
PNL: PNK_0349
 » show all
Reference
  Authors
Hernandez LD, Pypaert M, Flavell RA, Galan JE
  Title
A Salmonella protein causes macrophage cell death by inducing autophagy.
  Journal
J Cell Biol 163:1123-31 (2003)
DOI:10.1083/jcb.200309161
Reference
  Authors
Tran Van Nhieu G, Bourdet-Sicard R, Dumenil G, Blocker A, Sansonetti PJ
  Title
Bacterial signals and cell responses during Shigella entry into epithelial cells.
  Journal
Cell Microbiol 2:187-93 (2000)
DOI:10.1046/j.1462-5822.2000.00046.x
LinkDB

KEGG   ORTHOLOGY: K13286
Entry
K13286                      KO                                     
Symbol
sipC, ipaC, bipC
Name
invasin C
Pathway
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01079  Shigella IpaC to Actin signaling pathway
N01081  Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K13286  sipC, ipaC, bipC; invasin C
   05131 Shigellosis
    K13286  sipC, ipaC, bipC; invasin C
   05100 Bacterial invasion of epithelial cells
    K13286  sipC, ipaC, bipC; invasin C
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K13286  sipC, ipaC, bipC; invasin C
Cytoskeleton proteins [BR:ko04812]
 Prokaryotic cytoskeleton proteins
  Actin homologs
   Actin-binding proteins
    K13286  sipC, ipaC, bipC; invasin C
Genes
EMA: C1192_24315
STY: STY3007(sipC)
STT: t2786(sipC)
SEX: STBHUCCB_29300
SENT: TY21A_14075
STM: STM2884(sipC)
SEO: STM14_3483(sipC)
SEV: STMMW_28461
SEY: SL1344_2863(sipC)
SEM: STMDT12_C29330
SEJ: STMUK_2873(sipC)
SEB: STM474_3023(sipC)
SEF: UMN798_3132(sipC)
SENR: STMDT2_27831(sipC)
SEND: DT104_28811(sipC)
SENI: CY43_15060
SPT: SPA2742(sipC)
SEK: SSPA2556
SEI: SPC_2926(sipC)
SEC: SCH_2816(sipC)
SHB: SU5_03365
SENS: Q786_13880
SEG: SG2786(sipC)
SEL: SPUL_2881(sipC)
SEGA: SPUCDC_2867(sipC)
SET: SEN2725(sipC)
SENA: AU38_13840
SENO: AU37_13850
SENV: AU39_13850
SENQ: AU40_15595
SENL: IY59_14440
SEEP: I137_13730
SENB: BN855_29240(sipC)
SENE: IA1_13795
SBG: SBG_2504(sipC)
SBZ: A464_2908
SFL: CP0127(ipaC)
SFE: SFxv_4970(ipaC)
SSN: SSON_P089(ipaC)
SBC: SbBS512_A0159(ipaC)
SDY: SDY_P165(ipaC)
XAL: XALC_1505(xipC)
XPH: XppCFBP6546_12475(XppCFBP6546P_12475)
PFE: PSF113_1791(ipaC)
CVI: CV_2618(sipC)
CHAE: CH06BL_42040(cipC)
BMA: BMAA1530(bipC)
BML: BMA10229_2072(bipC)
BMN: BMA10247_A0754(bipC)
BMAL: DM55_4862
BMAE: DM78_4108
BMAQ: DM76_3815
BMAI: DM57_08300
BMAF: DM51_3236
BMAZ: BM44_4991
BMAB: BM45_3892
BPS: BPSS1531(bipC)
BPM: BURPS1710b_A0570(bipC)
BPSE: BDL_4840
BPSM: BBQ_4619
BPSU: BBN_4975
BPSD: BBX_4002
BPZ: BP1026B_II1627(bipC)
BPK: BBK_4140
BPSH: DR55_3745
BPSA: BBU_4504
BPSO: X996_3531
BUT: X994_5586
BTQ: BTQ_4129
BTJ: BTJ_5161
BTZ: BTL_3632
BTD: BTI_4010
BTV: BTHA_4256
BTHE: BTN_5615
BTHM: BTRA_3623
BTHA: DR62_3381
BTHL: BG87_3585
BOK: DM82_5838
BOC: BG90_4793
BUL: BW21_6004
PPNO: DA70_15440
PPNM: LV28_15240
PPUL: RO07_25420
PSPU: NA29_05195
 » show all
Reference
  Authors
Lilic M, Stebbins CE
  Title
Re-structuring the host cell: up close with Salmonella's molecular machinery.
  Journal
Microbes Infect 6:1205-11 (2004)
DOI:10.1016/j.micinf.2004.08.001
LinkDB

KEGG   ORTHOLOGY: K13287
Entry
K13287                      KO                                     
Symbol
sipD, ipaD, bipD
Name
invasin D
Pathway
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01081  Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K13287  sipD, ipaD, bipD; invasin D
   05100 Bacterial invasion of epithelial cells
    K13287  sipD, ipaD, bipD; invasin D
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K13287  sipD, ipaD, bipD; invasin D
Transporters [BR:ko02000]
 Other transporters
  Pores ion channels
   K13287  sipD, ipaD, bipD; invasin D
Other DBs
TC: 1.C.36.3
Genes
ECM: EcSMS35_4022
EUM: ECUMN_4184
ECT: ECIAI39_4256
EOC: CE10_4296(sipD)
ELO: EC042_4010
EAL: EAKF1_ch2271c
EMA: C1192_24320
STY: STY3006(sipD)
STT: t2785(sipD)
SEX: STBHUCCB_29290
STM: STM2883(sipD)
SEO: STM14_3482(sipD)
SEY: SL1344_2862(sipD)
SEJ: STMUK_2872(sipD)
SEB: STM474_3022(sipD)
SEF: UMN798_3131(sipD)
SENR: STMDT2_27821(sipD)
SEND: DT104_28801(sipD)
SENI: CY43_15055
SPT: SPA2741(sipD)
SEK: SSPA2555
SEI: SPC_2925(sipD)
SEC: SCH_2815(sipD)
SHB: SU5_03364
SENS: Q786_13875
SEG: SG2785(sipD)
SEL: SPUL_2880(sipD)
SEGA: SPUCDC_2866(sipD)
SET: SEN2724(sipD)
SENA: AU38_13835
SENO: AU37_13845
SENV: AU39_13845
SENQ: AU40_15590
SENL: IY59_14435
SEEP: I137_13725
SENE: IA1_13790
SBG: SBG_2503(sipD)
SBZ: A464_2907
SFL: CP0126(ipaD)
SFE: SFxv_4969(ipaD)
SSN: SSON_P088(ipaD)
SBC: SbBS512_A0158(ipaD)
SDY: SDY_P164(ipaD)
YEN: YE3535(yspD)
YEW: CH47_82
YAL: AT01_1830
YRU: BD65_2681
SGL: SG0006
EAM: EAMY_0792(sipD1) EAMY_1593(sipD3)
ETA: ETA_18940(sipD1) ETA_26800(sipD2)
EPY: EpC_19810(sipD)
EPR: EPYR_02139(sipD)
ERJ: EJP617_27380(sipD)
PSTW: DSJ_24175
PMR: PMI2681
PSI: S70_09740
PSX: DR96_1235
ANS: ArsFIN_08900(ipaD)
XAL: XALC_1477(xipD)
XPH: XppCFBP6546_12505(XppCFBP6546P_12505)
PFE: PSF113_1792(sipD)
PPUU: PputUW4_03621(sipD)
CVI: CV_2617(sipD)
CHAE: CH06BL_42030(cipD)
BMA: BMAA1528(bprD)
BML: BMA10229_2074(bipD)
BMN: BMA10247_A0757(bipD)
BMAL: DM55_4860
BMAE: DM78_4106
BMAQ: DM76_3813
BMAI: DM57_08310
BMAF: DM51_3234
BMAZ: BM44_4989
BMAB: BM45_3890
BPS: BPSS1529(bipD)
BPD: BURPS668_A2159(bipD)
BPSE: BDL_4838
BPSM: BBQ_4621
BPSU: BBN_4973
BPSD: BBX_4000
BPZ: BP1026B_II1625(bipD)
BPK: BBK_4138
BPSH: DR55_3747
BPSA: BBU_4506
BPSO: X996_3533
BUT: X994_5588
BTQ: BTQ_4131
BTJ: BTJ_5163
BTZ: BTL_3634
BTD: BTI_4008
BTV: BTHA_4254
BTHE: BTN_5617
BTHM: BTRA_3625
BTHA: DR62_3383
BTHL: BG87_3587
BOK: DM82_5836
BOC: BG90_4795
BUL: BW21_6002
PPNO: DA70_15435
PPNM: LV28_15245
PPUL: RO07_21070
PSPU: NA29_05200
 » show all
Reference
PMID:8522512
  Authors
Kaniga K, Trollinger D, Galan JE
  Title
Identification of two targets of the type III protein secretion system encoded by the inv and spa loci of Salmonella typhimurium that have homology to the Shigella IpaD and IpaA proteins.
  Journal
J Bacteriol 177:7078-85 (1995)
DOI:10.1128/jb.177.24.7078-7085.1995
  Sequence
Reference
  Authors
Cain RJ, Hayward RD, Koronakis V
  Title
Deciphering interplay between Salmonella invasion effectors.
  Journal
PLoS Pathog 4:e1000037 (2008)
DOI:10.1371/journal.ppat.1000037
Reference
  Authors
Picking WL, Nishioka H, Hearn PD, Baxter MA, Harrington AT, Blocker A, Picking WD
  Title
IpaD of Shigella flexneri is independently required for regulation of Ipa protein secretion and efficient insertion of IpaB and IpaC into host membranes.
  Journal
Infect Immun 73:1432-40 (2005)
DOI:10.1128/IAI.73.3.1432-1440.2005
LinkDB

DBGET integrated database retrieval system