KEGG ORTHOLOGY: K18903

ORTHOLOGY: K18903

Entry

K18903                      KO

Symbol

oprC, opcM

Name

outer membrane protein, multidrug efflux system

Module

M00698

Multidrug resistance, efflux pump BpeEF-OprC

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K18903  oprC, opcM; outer membrane protein, multidrug efflux system
   01504 Antimicrobial resistance genes
    K18903  oprC, opcM; outer membrane protein, multidrug efflux system
Transporters [BR:ko02000]
Other transporters
  Pores ion channels
   K18903  oprC, opcM; outer membrane protein, multidrug efflux system
Antimicrobial resistance genes [BR:ko01504]
Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump BpeEF-OprC
    K18903  oprC, opcM; outer membrane protein, multidrug efflux system

Other DBs

COG:

COG1538

TC:	1.B.17.3.3

Genes

PSSE:

OY559_18495

LRZ:	BJI69_06490 BJI69_08140

LPY:	FIV34_00365 FIV34_00890 FIV34_11760

LFL:	IM816_18150

LAEO:

L2Y97_00835

LAES:

L2Y96_00230 L2Y96_00725

PRE:	PCA10_22230

PPX:	T1E_5521(ttgF)

PTOL:

I7845_13820

PANH:

HU763_014095

PKK:	QQ992_12610

PSHS:

JJN09_07580

ACX:	Achr_23680

MFLI:

ACGK9W_06255

ACB:

A1S_2306

ABY:

ABAYE1172

ABC:	ACICU_02506

ABN:

AB57_2664

ABB:	ABBFA_01121(ttgC)

ABX:

ABK1_1182

ABZ:	ABZJ_02698

ABR:	ABTJ_01212

ABD:	ABTW07_2697

ABH:

M3Q_2772

ABAD:

ABD1_23050

ABJ:	BJAB07104_02663

ABAB:

BJAB0715_02708

ABAJ:

BJAB0868_02545

ABAZ:

P795_5370

ABK:	LX00_12465

ABAU:

IX87_07640

ABAA:

IX88_14515

ABW:	BL01_09020

ABAL:

ABLAC_11920

ACC:	BDGL_001799(oprM)

ANO:	RR32_06080

ALC:	OTEC02_05740

ACAL:

BUM88_13205

ASEI:

I8T81_06010

ACD:	AOLE_05495

ACW:	A0J50_05530

ADS:	FPL17_09220

AGYL:

FPL18_01610

AVZ:	HWI77_12385

APRL:

AVIV:

ACIE:

CVI:

CVC:	BKX93_10015

CHRO:

CXB49_02080

PSE:

NH8B_2719

AMAH:

DLM_0509

AQS:	DKK66_01030 DKK66_16110

RSO:	RSp1114 RSp1599

RSE:	F504_4078 F504_5069

RPU:	CDC45_23205 CDC45_25665

RNC:	GO999_19600 GO999_21885

RSL:	RPSI07_mp1155 RPSI07_mp1699

RSN:	RSPO_m00876 RSPO_m01583

RSM:	CMR15_mp20219 CMR15_mp30243

RSY:	RSUY_43260(oprM_7) RSUY_45770(ttgC_2)

RSG:	JK151_06800 JK151_18700

RPI:	Rpic_4223 Rpic_4898

RPF:	Rpic12D_3821 Rpic12D_4333

RPJ:	N234_06200 N234_26640

RMN:	TK49_18760 TK49_21765

RIN:	ACS15_4161 ACS15_5347

RWE:	KOL96_01520 KOL96_05140

REH:	H16_A1770(acrC4) H16_B1115(acrC9)

CNC:	CNE_2c10770(acrC2)

CUH:	BJN34_27250

REU:	Reut_B4333

RME:	Rmet_4865(nodT)

CTI:	RALTA_B0938

CBW:	RR42_s1436

CGD:	CR3_4349(tolC)

CPAU:

EHF44_24985

COX:	E0W60_03875 E0W60_10485

CCAM:

M5D45_16250 M5D45_25345

CCAX:

KZ686_21285

CUK:	KB879_10355 KB879_39005

CNAN:

A2G96_27180

CUPR:

IC580_22420

CUPE:

KLP38_26830

CUPP:

CTP10_R43970 CTP10_R62650

BMA:

BMAA1464

BML:	BMA10229_2144(oprC)

BMN:	BMA10247_A0829(oprC)

BMAZ:

BMAE:

BMAI:

BMAF:

BMAB:

BPS:

BPM:	BURPS1710b_A1842

BPL:	BURPS1106A_A0418(oprC)

BPD:	BURPS668_A0515(oprC)

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_II0323(oprC)

BPQ:	BPC006_II0397

BPK:

BPSH:

BPSA:

BPSO:

BUT:

BTE:	BTH_II2104

BTQ:

BTQ_5386

BTJ:

BTJ_4042

BTZ:

BTL_4860

BTD:	BTI_4438 BTI_5547

BTV:

BTHE:

BTHM:

BTHA:

BTHL:

BOK:	DM82_4299 DM82_4823

BOC:	BG90_3718 BG90_5771

BUU:	WS70_18865

BSAV:

WS86_20260

BHG:	I6G56_24385 I6G56_30920

BUD:	AQ610_21100 AQ610_27055

BVI:	Bcep1808_3578 Bcep1808_6376

BVE:	AK36_3182 AK36_5810

BUR:	Bcep18194_A4966 Bcep18194_B0297 Bcep18194_B1728

BCM:	Bcenmc03_3226 Bcenmc03_4920 Bcenmc03_7027

BCH:	Bcen2424_4291 Bcen2424_5350 Bcen2424_6360

BCJ:	BCAM1419 BCAM2549(opcM)

BCEN:

DM39_3585 DM39_5287

BCEW:

DM40_3183 DM40_4304 DM40_5859

BCEO:

I35_5273 I35_6447(opcM) I35_7709

BAM:	Bamb_3709 Bamb_4697

BAC:	BamMC406_4187 BamMC406_5228

BMJ:	BMULJ_04192 BMULJ_05151

BMU:	Bmul_3375 Bmul_4314

BMK:	DM80_3493 DM80_4754

BMUL:

NP80_4304 NP80_5171

BCT:	GEM_4333 GEM_5858

BCED:

DM42_3668 DM42_5424 DM42_7235

BCEP:

APZ15_17515 APZ15_23290 APZ15_32370 APZ15_35925

BDL:	AK34_3296 AK34_4100 AK34_5636

BPYR:

ABD05_22855 ABD05_29085 ABD05_32365

BCON:

NL30_05520 NL30_16545 NL30_31235

BUB:	BW23_3786 BW23_3863 BW23_5101

BDF:	WI26_20120 WI26_25595 WI26_30610

BLAT:

WK25_19485 WK25_23890 WK25_28505

BTEI:

WS51_04785 WS51_09665 WS51_30380

BSEM:

WJ12_20615 WJ12_26940 WJ12_32765

BPSL:

WS57_01370 WS57_06985 WS57_18140

BMEC:

WJ16_25495 WJ16_31260

BSTG:

WT74_25890 WT74_27440 WT74_31575

BSTL:

BBJ41_20165 BBJ41_26730

BANN:

JFN94_17090(opcM) JFN94_24170

BARI:

NLX30_24370(opcM) NLX30_31510

BAEN:

L3V59_20270 L3V59_27725(opcM)

BSER:

R0290_19390(opcM) R0290_26365 R0290_28965

BGL:	bglu_2g03560

BGU:

KS03_5564

BUG:	BC1001_4139 BC1001_5303

BGF:	BC1003_4118 BC1003_5277

BGD:	bgla_2g02590 bgla_2g05090 bgla_2g14640

BGO:	BM43_2797 BM43_5134 BM43_7277

BYI:	BYI23_B003940 BYI23_B007840

BUK:	MYA_3207 MYA_5747

BUL:	BW21_3960 BW21_5229

BUQ:	AC233_23490 AC233_28910

BGP:	BGL_2c04370 BGL_2c13450

BPLA:

bpln_2g04720

BUM:	AXG89_17365 AXG89_17735 AXG89_38490

BUI:	AX768_21865 AX768_27085 AX768_27515

BURK:

DM992_18800 DM992_24400 DM992_38620

BURT:

BTHE68_31240 BTHE68_35140

BURM:

GJG85_18300 GJG85_23845(opcM) GJG85_34265

BXE:	Bxe_A2893 Bxe_B0851 Bxe_B2070

BXB:	DR64_575 DR64_6173 DR64_7371

BPH:	Bphy_4636 Bphy_6520

BGE:	BC1002_3542 BC1002_4407

BPX:	BUPH_00721 BUPH_05778

BPY:	Bphyt_4536 Bphyt_5874

BUZ:	AYM40_26615 AYM40_27630 AYM40_29825 AYM40_30255 AYM40_31070

BFN:	OI25_4481 OI25_6602

BCAI:

K788_0003982 K788_0004754 K788_0005422 K788_0007421

PSPW:

BJG93_17705 BJG93_23935

PARA:

BTO02_13515 BTO02_32325

PARB:

CJU94_19845 CJU94_24835

PHS:	C2L64_21590 C2L64_24040 C2L64_29435 C2L64_38105

PTER:

C2L65_18940 C2L65_24035 C2L65_26400 C2L65_34080

PGP:	CUJ91_20055 CUJ91_27305

PCJ:	CUJ87_17700 CUJ87_24060

PTS:	CUJ90_20505 CUJ90_27570

PCAF:

DSC91_001921

PMEG:

FNZ07_01695 FNZ07_12675

PTRO:

G5S35_19035 G5S35_19975

PGIS:

I6I06_19895 I6I06_25320

PACP:

FAZ97_14570 FAZ97_15960

PACS:

FAZ98_19705 FAZ98_20545

PEW:	KZJ38_09180 KZJ38_20450 KZJ38_35155

PDIO:

PDMSB3_1059.1 PDMSB3_1107 PDMSB3_2537.1

PBRY:

NDK50_25180 NDK50_32060

PSAA:

QEN71_20105 QEN71_32630 QEN71_37925

PKF:	RW095_11140 RW095_18150

PBON:

QS306_14865

PPAI:

E1956_23170 E1956_25870 E1956_33365

PHUN:

U0042_06810

PLAD:

PPGU16_40680 PPGU16_42670 PPGU16_52780 PPGU16_69960

PAZZ:

PBP221_37590 PBP221_49380 PBP221_51340 PBP221_72480

PPK:	U875_12195 U875_25870

PPNO:

DA70_02685 DA70_04595

PPNM:

LV28_01675 LV28_03655

PRB:	X636_22505 X636_24425

PPUL:

RO07_22530

PSPU:

NA29_14395 NA29_16600

PAPI:

SG18_19715 SG18_21790

PVE:	UC34_14035

POX:	MB84_16240 MB84_18580

PFG:	AB870_22230

PNR:	AT302_18080 AT302_21200

PAND:

DRB87_10805 DRB87_12935

PFIB:

PI93_014040 PI93_015840

PCOM:

NTU39_12905 NTU39_15625

PANN:

PanNE5_34080 PanNE5_37940

PANX:

OYT13_10755 OYT13_13310

CABA:

SBC2_43380(ttgF_1) SBC2_59890(ttgF_2) SBC2_65000(ttgF_3)

BUO:	BRPE64_BCDS05370 BRPE64_BCDS09320

CABK:

NK8_34070 NK8_37980

BUE:	BRPE67_BCDS06520 BRPE67_BCDS11810

TVL:	FAZ95_30795 FAZ95_33945

TCAR:

U0034_22985

BPAR:

BN117_0430

BPA:

BPP0433

BBH:	BN112_2978

BBR:

BB0435

BBM:	BN115_0422

BBX:	BBS798_0431

BPT:	Bpet4510(oprM)

BAV:

BAV0324

BHZ:	ACR54_00385(ttgI_1)

BTRM:

SAMEA390648701570(oprM_2)

BBRO:

BAU06_01865 BAU06_12045 BAU06_13530

BFZ:	BAU07_14565

BPDZ:

BBN53_19000

BOH:	AKI39_11205

BGM:	CAL15_21775

BOJ:	CBF45_07955

BGV:	CAL12_01915 CAL12_12565 CAL12_14110

AXY:	AXYL_03072 AXYL_05888

AXO:	NH44784_027171

AXN:	AX27061_5588

AXX:	ERS451415_05611(oprM_9)

ADT:	APT56_25770

AIS:	BUW96_28560

ASW:	CVS48_09435

ACHR:

C2U31_01840 C2U31_07395

ACHB:

DVB37_25335

ADY:	HLG70_08265 HLG70_24185

ACHO:

H4P35_24400

AMUI:

PE062_21125

APES:

FOC84_15990 FOC84_30315

AAEG:

RA224_02985 RA224_17635

ASEL:

RAS12_08090 RAS12_25270

ACHM:

V6V88_24980

ACHA:

KYT87_26580

AVH:	WHX56_01490

ACHH:

ABFG95_12400

PUT:

PT7_0148

PUS:	CKA81_05420

POLL:

OEG81_09525

CGIN:

ABRZ00_11185

ODI:

ODI_R1300

PIG:	EGT29_14055

PACR:

FXN63_19375

KGY:	EHF36_08110

PARK:

LSG25_02005

RHY:	RD110_05535

POL:

Bpro_3427

PNA:	Pnap_0566 Pnap_1300

POS:	DT070_13200

POO:	F7R28_17410

ACK:	C380_08100

ACIO:

ARAD:

ATEM:

ACIQ:

ACIV:

ASAH:

AAV:

AAA:

AMON:

DAC:

DEL:	DelCs14_1477

DTS:	BI380_29595

DHK:	BO996_23685

DLA:	I6G47_30350

VAP:	Vapar_2564

VPE:	Varpa_1854 Varpa_3359

VPD:	VAPA_1c29890 VAPA_2c09420

VAA:	AX767_15920 AX767_18640

VBO:	CKY39_15900

VAM:	C4F17_06805 C4F17_27490

VAZ:	H7F35_22450 H7F35_32880

VAV:	IG196_13500

VAE:	RZE79_14085

VAX:	H7F36_18955

CTT:	CtCNB1_2119

CTES:

CODO:

CTEZ:

AANT:

CRJ:	QMY55_10840

CENP:

M9799_17750

COMB:

MJ205_08235

CSQU:

N4T19_04425

HYR:	BSY239_2318

HYB:

Q5W_00930

HYN:	F9K07_17045

HCZ:	G9Q37_19875

HYY:	JNX00_03505

HYDR:

SOM08_03145

HYDA:

ABSY19_22885

DPY:	BA022_10080

DIH:	G7047_28595

DRG:	H9K76_19040

DIA:	Dtpsy_0943

HGR:	DW355_16550

STHM:

IS481_16785

PBH:	AAW51_3194(oprC)

MPT:

Mpe_A0867

METP:

C1M51_13380

RGE:

RGE_00130

RDP:	RD2015_812

ROI:	N4261_04705

KIA:	G8A07_04105

PAIS:

PFX98_02810

MIU:	ABE85_18595

IDC:	LRM40_01495

ATER:

MW290_17300

RGU:	A4W93_02005

MMS:	mma_0022(tolC1) mma_1566

JAG:	GJA_1108 GJA_2910

JAZ:	YQ44_04010 YQ44_08730

JAL:	BZG29_19075 BZG29_23535

JSV:	CNX70_19275 CNX70_23980

JAJ:	EKL02_02000

JAS:	FJQ89_09020 FJQ89_13215

JLV:	G3257_19795 G3257_24220

JAH:	JAB4_039040(oprM_3) JAB4_047970(oprJ)

JRI:	P9875_19655 P9875_24525

HSE:	Hsero_0314 Hsero_4616(tolC)

HSZ:	ACP92_01555 ACP92_23060

HHT:	F506_00380 F506_04725

HRB:	Hrubri_0289 Hrubri_4552(tolC)

HEE:	hmeg3_00950 hmeg3_22165

HHF:	E2K99_01650 E2K99_24305

HFR:	G5S34_01435 G5S34_24175

HEW:	HBDW_02710 HBDW_47520

CFU:

CFU_2592

CARE:

LT85_0272(cmeC) LT85_2012(cmeC)

CPRA:

CPter91_3343

MNR:	ACZ75_08330 ACZ75_24560

MASW:

AM586_23020 AM586_24935

MASS:

CR152_13995 CR152_22365

MTIM:

DIR46_16535 DIR46_18680

MASY:

DPH57_08705 DPH57_25840

MANC:

IV454_01595 IV454_25595

MFY:	HH212_11185 HH212_12960

MVAR:

MasN3_42340

MENY:

LSQ66_06725 LSQ66_07255 LSQ66_16230

MLIR:

LPB04_08480 LPB04_10395

MASH:

LP419_27785

MASZ:

C9I28_12915 C9I28_23455

MALI:

EYF70_03885 EYF70_15765

MUM:	FCL38_02685 FCL38_14745 FCL38_17150

MFLA:

GO485_10170 GO485_28020

MPLI:

E1742_00490 E1742_10520

TCT:	PX653_09900 PX653_27460

PLUE:

EWM63_00020 EWM63_18475 EWM63_28220

DUG:	HH213_04895 HH213_11115 HH213_23135

DZO:	SR858_04430 SR858_15515

TMJ:	P0M04_12300 P0M04_14410

RUG:	QC826_04765 QC826_10100

EHB:	E7V67_010605 E7V67_021250

UND:	UNDKW_4680

UNY:	UNDYM_4646

GLC:	JQN73_03295

XYK:	GT347_22975

XYG:	R9X41_14020

ETB:	N7L95_10020

BBAG:

E1O_09750

METR:

BSY238_3391

MFA:

Mfla_1794

MEI:	Msip34_2482

MEP:

MPQ_2428

MPAU:

ZMTM_04810

URU:	DSM104443_01882(oprM_2) DSM104443_03101(oprM_4)

UPL:	DSM104440_02744(oprM_3)

DSU:

Dsui_2027

OTR:	OTERR_17010(oprC)

APET:

ToN1_04560

DAR:

Daro_3827

DDEN:

KI615_08500

AZO:	azo2570(opcM2)

AOA:

dqs_2731

AZA:

AZKH_2577

AZI:	AzCIB_1189

AZR:	CJ010_16240

AZQ:	G3580_09795

BEBA:

BWI17_11455

SHIN:

LHJ69_07825

CAK:

Caul_5123

AEX:	Astex_1276

ASTI:

Q1W73_05490

ASTD:

ATDW_11080

ASTM:

MMA231_00542(ttgI_1)

DVE:	DESUT3_38300

DES:	DSOUD_2501

DPS:

DP2121

DAK:	DaAHT2_0625

DML:	Dmul_20410

DLI:	dnl_33930 dnl_42090

DMM:	dnm_015830

OTE:

Oter_3811

VBH:	CMV30_15900

OBT:	OPIT5_19485

RUFI:

K0V07_02800

PUO:	RZN69_07845

LAMB:

KBB96_13215

LUI:

llg_04710

VEG:	SAMN05444156_0779

GRB:	GOB94_12665

TSA:	AciPR4_2289

TALB:

SUS:

PRHO:

Reference

PMID:17005832

Authors

Kumar A, Chua KL, Schweizer HP

Title

Method for regulated expression of single-copy efflux pump genes in a surrogate Pseudomonas aeruginosa strain: identification of the BpeEF-OprC chloramphenicol and trimethoprim efflux pump of Burkholderia pseudomallei 1026b.

Journal

Antimicrob Agents Chemother 50:3460-3 (2006)
DOI:10.1128/AAC.00440-06

Sequence

[bps:BPSS0294]

LinkDB

DBGET integrated database retrieval system