KEGG ORTHOLOGY: K23932

ORTHOLOGY: K23932

Entry

K23932                      KO

Symbol

SPTBN2

Name

spectrin beta, non-erythrocytic 2

Pathway

map04517

IgSF CAM signaling

map04820

Cytoskeleton in muscle cells

map05017

Spinocerebellar ataxia

map05022

Pathways of neurodegeneration - multiple diseases

Disease

H00063

Spinocerebellar ataxia (SCA)

H01891

Autosomal recessive spinocerebellar ataxias

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    K23932  SPTBN2; spectrin beta, non-erythrocytic 2
09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    K23932  SPTBN2; spectrin beta, non-erythrocytic 2
09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K23932  SPTBN2; spectrin beta, non-erythrocytic 2
   05022 Pathways of neurodegeneration - multiple diseases
    K23932  SPTBN2; spectrin beta, non-erythrocytic 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K23932  SPTBN2; spectrin beta, non-erythrocytic 2
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     K23932  SPTBN2; spectrin beta, non-erythrocytic 2
  Intermediate filaments
   Intermediate filament-binding proteins
    K23932  SPTBN2; spectrin beta, non-erythrocytic 2

Other DBs

GO:

0008091

Genes

HSA:	6712(SPTBN2)

PTR:	451353(SPTBN2)

PPS:	100979785(SPTBN2)

GGO:	101124405(SPTBN2)

PON:	100436821(SPTBN2)

PPYG:

129008361(SPTBN2)

NLE:	100599402(SPTBN2)

HMH:	116469060(SPTBN2)

SSYN:

129474808(SPTBN2)

MCC:	713419(SPTBN2)

MCF:	102118488(SPTBN2)

MTHB:

126935322

MNI:	105469651(SPTBN2)

CSAB:

103221616(SPTBN2)

CATY:

105577376(SPTBN2)

PANU:

101022878(SPTBN2)

TGE:	112606296(SPTBN2)

MLEU:

105544448(SPTBN2)

RRO:	104664760(SPTBN2)

RBB:	108518666(SPTBN2)

TFN:	117080166(SPTBN2)

PTEH:

111522222(SPTBN2)

CANG:

105512106(SPTBN2)

CJC:	100400444(SPTBN2)

SBQ:	101050402(SPTBN2)

CIMI:

108310199(SPTBN2)

ANAN:

105706500(SPTBN2)

CSYR:

103268324(SPTBN2)

MMUR:

105867459(SPTBN2)

LCAT:

123642877(SPTBN2)

ERUF:

138385411(SPTBN2)

PCOQ:

105827450(SPTBN2)

OGA:	100942538(SPTBN2)

MMU:	20743(Sptbn2)

MCAL:

110285742(Sptbn2)

MPAH:

110328630(Sptbn2)

RNO:	29211(Sptbn2)

MCOC:

116103344(Sptbn2)

ANU:	117723696(Sptbn2)

ASYL:

127692672(Sptbn2)

MUN:	110556495(Sptbn2)

CGE:	100758389(Sptbn2)

MAUA:

101822353(Sptbn2)

PROB:

127228656(Sptbn2)

PLEU:

114709123(Sptbn2)

PMAV:

102917647(Sptbn2)

MORG:

121454619(Sptbn2)

MFOT:

126498697

AAMP:

119817270(Sptbn2)

CNL:	130879137(Sptbn2)

NGI:	103725563(Sptbn2)

HGL:	101714181(Sptbn2)

CPOC:

100731189(Sptbn2)

CCAN:

109687065(Sptbn2)

DORD:

105989229(Sptbn2)

DSP:	122105315(Sptbn2)

DMER:

138818800 138824351

PLOP:

125361274(Sptbn2)

NCAR:

124958385

MMMA:

107156988(Sptbn2)

ITI:	101976192(Sptbn2)

OCU:

100355265

OPI:	101520460(SPTBN2)

OCZ:	121150125(SPTBN2)

TUP:	102485789(SPTBN2)

GVR:	103595563(SPTBN2)

CFA:	483706(SPTBN2)

CLUD:

112659225(SPTBN2)

VVP:	112924201(SPTBN2)

VLG:	121472014(SPTBN2)

NPO:	129503104(SPTBN2)

AML:	100483386(SPTBN2)

UMR:	103679603(SPTBN2)

UAH:	113244052(SPTBN2)

UAR:	123778397(SPTBN2)

ELK:

111149653

LLV:

125078449

MPUF:

101687155(SPTBN2)

MNP:	132018047(SPTBN2)

MLK:	131816150(SPTBN2)

NVS:	122913165(SPTBN2)

ORO:	101362797(SPTBN2)

EJU:	114220377(SPTBN2)

ZCA:	113914909(SPTBN2)

MLX:	118016107(SPTBN2)

MANO:

123840434(SPTBN2)

NSU:	110576376(SPTBN2)

LWW:

102733959

FCA:	101089045(SPTBN2)

PYU:	121023832(SPTBN2)

PCOO:

112851955(SPTBN2)

PBG:	122484029(SPTBN2)

PVIV:

125177008(SPTBN2)

LRUF:

124505590

LGF:	123601966(SPTBN2)

AJU:

106971114

PTG:	102972511(SPTBN2)

PPAD:

109246814(SPTBN2)

PUC:

125911637

PLEZ:

122199643(SPTBN2)

HHV:	120240128(SPTBN2)

CCRU:

144237735(SPTBN2)

BTA:	132344210(SPTBN2)

BOM:	102269667(SPTBN2)

BIU:	109554137(SPTBN2)

BBUB:

102407160(SPTBN2)

BKE:	129654125(SPTBN2)

BBIS:

104986983(SPTBN2)

CHX:	102179357(SPTBN2)

OAS:	101106728(SPTBN2)

BTAX:

128068676(SPTBN2)

CSUM:

138082933(SPTBN2)

ODA:	120874756(SPTBN2)

CCAD:

122430642(SPTBN2)

MREE:

136169778(SPTBN2)

OVR:	110145983(SPTBN2)

MBEZ:

129548715(SPTBN2)

SSC:	110259235(SPTBN2)

CFR:	102523306(SPTBN2)

CBAI:

105070314(SPTBN2)

CDK:	105104446(SPTBN2)

VPC:	102539269(SPTBN2)

BACU:

103015074(SPTBN2)

BMUS:

118899163(SPTBN2)

LVE:	103071400(SPTBN2)

OOR:	101281021(SPTBN2)

LALB:

132525590(SPTBN2)

GMF:	115840477(SPTBN2)

DDP:	132430112(SPTBN2)

DLE:	111183696(SPTBN2)

PCAD:

102978787(SPTBN2)

PSIU:

116758561(SPTBN2)

PPHC:

136127412(SPTBN2)

NASI:

112402302(SPTBN2)

ECB:	100052745(SPTBN2)

EPZ:	103559772(SPTBN2)

EAI:	106833515(SPTBN2)

MYB:	102242735(SPTBN2)

MYD:	102766105(SPTBN2)

MMYO:

118665243(SPTBN2)

MLF:	102417018(SPTBN2)

MDT:	132241353(SPTBN2)

MYUM:

139018796(SPTBN2)

PKL:	118706973(SPTBN2)

EFUS:

103290940(SPTBN2)

MNA:	107533592(SPTBN2)

DRO:	112317150(SPTBN2)

SHON:

118991794(SPTBN2)

AJM:	119041833(SPTBN2)

PDIC:

114498560(SPTBN2)

PHAS:

123829304(SPTBN2)

MMF:	118628114(SPTBN2)

PPAM:

129068544(SPTBN2)

HAI:	109384199(SPTBN2)

RFQ:	117031253(SPTBN2)

PALE:

102895582(SPTBN2)

PGIG:

120584784(SPTBN2)

PVP:	105297957(SPTBN2)

RAY:	107503879(SPTBN2)

MJV:	108401331(SPTBN2)

TOD:	119249926(SPTBN2)

SARA:

101546498(SPTBN2)

SFUM:

130039939(SPTBN2)

SETR:

126018092(SPTBN2)

LAV:	100673614(SPTBN2)

TMU:

101348535

ETF:	101643980(SPTBN2)

DNM:	101422154(SPTBN2)

MDO:	100015194(SPTBN2)

GAS:	123253022(SPTBN2)

SHR:	100926336(SPTBN2)

AFZ:

127541897

PCW:	110195354(SPTBN2)

TVP:	118853052(SPTBN2)

PBRV:

138144901(SPTBN2)

MLAO:

141518708(SPTBN2)

OAA:	100091346(SPTBN2)

TACU:

119943308(SPTBN2)

GGA:	101750255(SPTBN2)

CJO:

107307541

APLA:

119715099(SPTBN2)

AACU:

137848995(SPTBN2)

ACYG:

125181675 136789300

CATA:

118261570(SPTBN2)

TGU:

LSR:

PMOA:

OTC:

PRUF:

ATRC:

139586337(SPTBN2)

OMA:

130262609

PHI:	102104853(SPTBN2)

PMAJ:

107199096

ACOE:

138100271

ZLE:

135460260

SVG:	106864158(SPTBN2)

HRT:

120747641

SATI:

136374789

CCIC:

134055613

SHAB:

115614663(SPTBN2)

ACHC:

115338328(SPTBN2)

HLE:	104835239(SPTBN2)

AGEN:

126053390

HHAR:

128138045

BBUT:

142025692(SPTBN2)

NNI:

104014143

CBOR:

142074496(SPTBN2)

CBOY:

140660439(SPTBN2)

MAME:

142421483(SPTBN2)

CNIC:

136000270(SPTBN2)

CUCA:

104055543(SPTBN2)

RTD:	128901799(SPTBN2)

CRID:

134508088(SPTBN2)

LMIC:

141735371(SPTBN2)

AROW:

112963170

NPD:

112958297

ASN:	102369324(SPTBN2)

AMJ:	102558393(SPTBN2)

CPOO:

109318247(SPTBN2)

PSS:	102460944(SPTBN2)

CIZ:	142018766(SPTBN2)

CMY:	102947557(SPTBN2)

CCAY:

125639389(SPTBN2)

LKP:	140914385(SPTBN2)

NDS:	141990627(SPTBN2)

DCC:	119858451(SPTBN2)

CPIC:

101931531(SPTBN2)

TST:	117879877(SPTBN2)

CABI:

116835661(SPTBN2)

MRV:	120408883(SPTBN2)

ACS:	100564031(sptbn2)

ASAO:

132764380(SPTBN2)

PVT:	110089966(SPTBN2)

SUND:

121915232(SPTBN2)

PBI:	103055217(SPTBN2)

PMUR:

107288994(SPTBN2)

CTIG:

120318527(SPTBN2)

TSR:

106538028

PGUT:

117669700(SPTBN2)

PCAE:

139322268(SPTBN2)

APRI:

131186485(SPTBN2)

PTEX:

113446678(SPTBN2)

NSS:	113426675(SPTBN2)

VKO:	123032671(SPTBN2)

PMUA:

114586572(SPTBN2)

PRAF:

128404156(SPTBN2)

ZVI:	118076591(SPTBN2)

HCG:	128337072(SPTBN2)

GJA:	107111050(SPTBN2)

STOW:

125437131(SPTBN2)

EMC:	129336758(SPTBN2)

XLA:	108715130 398511(sptbn2.L)

XTR:	100486199(sptbn2)

NPR:

108798080

RTEM:

120917482(SPTBN2)

ACAT:

141112358(SPTBN2)

PADS:

140338719(SPTBN2)

BBUF:

120980793(SPTBN2)

BGAR:

122920830(SPTBN2)

DTC:

141058425

HSQ:	130277076(SPTBN2)

PWL:	138259873(SPTBN2)

MUO:	115479679(SPTBN2)

GSH:	117365341(SPTBN2)

DRE:	558044(sptbn2)

SRX:	107734132 107746380

SANH:

107661190 107663413

SGH:	107548459 107596124

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:	141334514(sptbn2)

OMC:	131541452(sptbn2)

PPRM:

RKG:

MAMB:

CIDE:

CERY:

137033578(sptbn2)

MASI:

127427795 127433510

TROS:

130565635

TDW:

130419165

MANU:

129440410(sptbn2)

PDAB:

135748832(sptbn2)

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:	132841152(sptbn2)

CGAR:

128512018

NGRA:

132875551(sptbn2)

TRN:	134303075(sptbn2)

AMEX:

103032213

CMAO:

118814642

CHAR:

105912481

SPIL:

134080240(sptbn2)

ASAD:

121710080

TRU:

101069768

TFS:

130537187

TNG:	GSTEN00019086G001

LCO:

104935289

TBEN:

117490648

CGOB:

115018454

PGEO:

117458654(sptbn2)

GACU:

117535623

EMAC:

134871586(sptbn2)

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

119215879(sptbn2)

AFB:

129114073

CLUM:

117742938

PSWI:

130213000

CANA:

137802851(sptbn2)

CVE:	137876562(sptbn2)

MSAM:

119895052

SCHU:

122888453

EARM:

139295712(sptbn2)

CUD:

121518325

SPUL:

138597579(sptbn2)

LMIX:

132987796(sptbn2)

HTC:	141791419(sptbn2)

ALAT:

119030956

ASTR:

137605835(sptbn2)

PKLU:

139213531(sptbn2)

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

133459431 133459565(sptbn2)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

EJA:	138196488(sptbn2)

BFRE:

138631481(sptbn2)

MCEP:

CSEM:

POV:

SSEN:

SSOE:

131458054(sptbn2)

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

125981762(sptbn2)

SBIA:

133491685(sptbn2)

PEE:	133415632(sptbn2)

PTAO:

133466959(sptbn2)

BPEC:

110158618

ENY:	140360851(sptbn2)

MALB:

109959398

BSPL:

114869139

SJO:

128371925

SSCO:

133994256(sptbn2)

TTY:	137195499(sptbn2)

GMH:

115547662

SASA:

106563448 106603118

STRU:

115154710 115204318

OTW:	112228845 112231300

OMY:	110510012 110534017

OGO:

124006821

ONE:	115101359 115135592

OKI:	109872957 109874410

OKE:	118385080 118390395

OMM:

135550390

OCLA:

139387895 139418550

SALP:

111950442

SNH:	120021052 120057259

SFON:

129863925 129868939

CCLU:

121541873 121579513

ELS:

105027840

OEP:	134039841(sptbn2)

SFM:	108925411 108934380

PKI:	111839545 111859833(sptbn2)

AANG:

118222918 118235809

AROT:

135250115 135262855

CCOG:

133123358 133132497(sptbn2)

LOC:

PSPA:

ARUT:

PSEX:

LCM:

RTP:

CPLA:

CPUN:

HOC:

LERI:

HAKA:

Reference

PMID:9826670

Authors

Stankewich MC, Tse WT, Peters LL, Ch'ng Y, John KM, Stabach PR, Devarajan P, Morrow JS, Lux SE

Title

A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles.

Journal

Proc Natl Acad Sci U S A 95:14158-63 (1998)
DOI:10.1073/pnas.95.24.14158

Sequence

[hsa:6712]

LinkDB

DBGET integrated database retrieval system