KEGG   REACTION: R01939
Entry
R01939                      Reaction                               
Name
L-2-aminoadipate:2-oxoglutarate aminotransferase
Definition
L-2-Aminoadipate + 2-Oxoglutarate <=> 2-Oxoadipate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026  C00322_C00956
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
K05825  2-aminoadipate transaminase [EC:2.6.1.-]
Reference
1  [PMID:15256574]
  Authors
Miyazaki T, Miyazaki J, Yamane H, Nishiyama M.
  Title
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.
  Journal
Microbiology 150:2327-34 (2004)
DOI:10.1099/mic.0.27037-0
Other DBs
RHEA: 12604
LinkDB

KEGG   RCLASS: RC00006
Entry
RC00006                     RClass                                 
Definition
C1c-C5a:N1a+*-*+O5a:C1b+C6a-C1b+C6a
Reactant pair
Related class
Reaction
Enzyme
1.4.1.2         1.4.1.3         1.4.1.4         1.4.1.7         
1.4.1.9         1.4.1.13        1.4.1.14        1.4.1.16        
1.4.1.19        1.4.1.20        1.4.1.21        1.4.1.25        
1.4.1.-         1.4.3.1         1.4.3.2         1.4.3.3         
1.4.3.7         1.4.3.11        1.4.3.14        1.4.3.15        
1.4.3.16        1.4.3.25        1.4.5.1         1.4.7.1         
1.4.99.6        1.13.12.15      2.6.1.1         2.6.1.2         
2.6.1.3         2.6.1.4         2.6.1.5         2.6.1.6         
2.6.1.7         2.6.1.8         2.6.1.9         2.6.1.11        
2.6.1.12        2.6.1.13        2.6.1.14        2.6.1.15        
2.6.1.17        2.6.1.19        2.6.1.21        2.6.1.22        
2.6.1.23        2.6.1.24        2.6.1.26        2.6.1.27        
2.6.1.28        2.6.1.29        2.6.1.31        2.6.1.33        
2.6.1.34        2.6.1.35        2.6.1.36        2.6.1.38        
2.6.1.39        2.6.1.41        2.6.1.42        2.6.1.44        
2.6.1.45        2.6.1.48        2.6.1.49        2.6.1.50        
2.6.1.51        2.6.1.52        2.6.1.54        2.6.1.55        
2.6.1.57        2.6.1.58        2.6.1.59        2.6.1.60        
2.6.1.62        2.6.1.63        2.6.1.64        2.6.1.65        
2.6.1.67        2.6.1.70        2.6.1.72        2.6.1.73        
2.6.1.74        2.6.1.75        2.6.1.76        2.6.1.78        
2.6.1.79        2.6.1.80        2.6.1.81        2.6.1.82        
2.6.1.83        2.6.1.84        2.6.1.87        2.6.1.88        
2.6.1.89        2.6.1.90        2.6.1.92        2.6.1.93        
2.6.1.94        2.6.1.95        2.6.1.98        2.6.1.99        
2.6.1.100       2.6.1.101       2.6.1.102       2.6.1.103       
2.6.1.104       2.6.1.106       2.6.1.107       2.6.1.110       
2.6.1.114       2.6.1.116       2.6.1.118       2.6.1.120       
2.6.1.-
 » show all
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00220  Arginine biosynthesis
rn00250  Alanine, aspartate and glutamate metabolism
rn00260  Glycine, serine and threonine metabolism
rn00261  Monobactam biosynthesis
rn00270  Cysteine and methionine metabolism
rn00280  Valine, leucine and isoleucine degradation
rn00290  Valine, leucine and isoleucine biosynthesis
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn00311  Penicillin and cephalosporin biosynthesis
rn00330  Arginine and proline metabolism
rn00340  Histidine metabolism
rn00350  Tyrosine metabolism
rn00360  Phenylalanine metabolism
rn00380  Tryptophan metabolism
rn00400  Phenylalanine, tyrosine and tryptophan biosynthesis
rn00401  Novobiocin biosynthesis
rn00430  Taurine and hypotaurine metabolism
rn00440  Phosphonate and phosphinate metabolism
rn00450  Selenocompound metabolism
rn00470  D-Amino acid metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn00660  C5-Branched dibasic acid metabolism
rn00680  Methane metabolism
rn00710  Carbon fixation in photosynthetic organisms
rn00950  Isoquinoline alkaloid biosynthesis
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00966  Glucosinolate biosynthesis
rn00998  Biosynthesis of various antibiotics
rn00999  Biosynthesis of various plant secondary metabolites
rn01055  Biosynthesis of vancomycin group antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
RModule
RM901  Reductive amination of 2-oxocarboxylic acid
Orthology
K00260  glutamate dehydrogenase [EC:1.4.1.2]
K00261  glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
K00262  glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
K00263  leucine dehydrogenase [EC:1.4.1.9]
K00264  glutamate synthase (NADH) [EC:1.4.1.14]
K00265  glutamate synthase (NADPH) large chain [EC:1.4.1.13]
K00266  glutamate synthase (NADPH) small chain [EC:1.4.1.13]
K00270  phenylalanine dehydrogenase [EC:1.4.1.20]
K00272  D-aspartate oxidase [EC:1.4.3.1]
K00273  D-amino-acid oxidase [EC:1.4.3.3]
K00278  L-aspartate oxidase [EC:1.4.3.16]
K00284  glutamate synthase (ferredoxin) [EC:1.4.7.1]
K00285  D-amino-acid dehydrogenase [EC:1.4.5.1]
K00811  aspartate aminotransferase, chloroplastic [EC:2.6.1.1]
K00812  aspartate aminotransferase [EC:2.6.1.1]
K00813  aspartate aminotransferase [EC:2.6.1.1]
K00814  alanine transaminase [EC:2.6.1.2]
K00815  tyrosine aminotransferase [EC:2.6.1.5]
K00816  kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K00817  histidinol-phosphate aminotransferase [EC:2.6.1.9]
K00818  acetylornithine aminotransferase [EC:2.6.1.11]
K00819  ornithine--oxo-acid transaminase [EC:2.6.1.13]
K00821  acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
K00823  4-aminobutyrate aminotransferase [EC:2.6.1.19]
K00824  D-alanine transaminase [EC:2.6.1.21]
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
K00826  branched-chain amino acid aminotransferase [EC:2.6.1.42]
K00827  alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40]
K00830  alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
K00831  phosphoserine aminotransferase [EC:2.6.1.52]
K00832  aromatic-amino-acid transaminase [EC:2.6.1.57]
K00833  adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
K00836  diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
K00837  aromatic aminotransferase [EC:2.6.1.-]
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
K00840  succinylornithine aminotransferase [EC:2.6.1.81]
K00841  aminotransferase [EC:2.6.1.-]
K02805  dTDP-4-amino-4,6-dideoxygalactose transaminase [EC:2.6.1.59]
K03334  L-amino-acid oxidase [EC:1.4.3.2]
K03340  diaminopimelate dehydrogenase [EC:1.4.1.16]
K03918  L-lysine 6-transaminase [EC:2.6.1.36]
K05821  aromatic amino acid aminotransferase II [EC:2.6.1.58 2.6.1.28]
K05825  2-aminoadipate transaminase [EC:2.6.1.-]
K05830  LysW-gamma-L-lysine/LysW-L-ornithine aminotransferase [EC:2.6.1.118 2.6.1.-]
K05957  L-glutamine:scyllo-inosose aminotransferase [EC:2.6.1.50]
K07250  4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
K07806  UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC:2.6.1.87]
K09251  putrescine aminotransferase [EC:2.6.1.82]
K10206  LL-diaminopimelate aminotransferase [EC:2.6.1.83]
K11358  aspartate aminotransferase [EC:2.6.1.1]
K12252  arginine:pyruvate transaminase [EC:2.6.1.84]
K13010  perosamine synthetase [EC:2.6.1.102]
K13017  UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase [EC:2.6.1.98]
K13290  serine---pyruvate transaminase [EC:2.6.1.51]
K13308  dTDP-4-amino-4,6-dideoxy-D-glucose transaminase [EC:2.6.1.33]
K13310  dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase [EC:2.6.1.106]
K13329  dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase [EC:2.6.1.110]
K13524  4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
K13547  L-glutamine:2-deoxy-scyllo-inosose/3-amino-2,3-dideoxy-scyllo-inosose aminotransferase [EC:2.6.1.100 2.6.1.101]
K13553  neamine transaminase [EC:2.6.1.93]
K14260  alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
K14264  kynurenine aminotransferase [EC:2.6.1.7]
K14265  tryptophan aminotransferase [EC:2.6.1.27]
K14267  N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]
K14268  5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19]
K14271  nicotianamine aminotransferase [EC:2.6.1.80]
K14272  glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44]
K14287  methionine transaminase [EC:2.6.1.88]
K14454  aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14455  aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
K15371  glutamate dehydrogenase [EC:1.4.1.2]
K15372  taurine---2-oxoglutarate transaminase [EC:2.6.1.55]
K15785  L-2,4-diaminobutyrate transaminase [EC:2.6.1.76]
K15849  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [EC:2.6.1.1 2.6.1.78 2.6.1.79]
K15895  UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine transaminase [EC:2.6.1.92]
K15910  UDP-N-acetylbacillosamine transaminase [EC:2.6.1.34]
K16016  3-amino-5-hydroxybenzoate synthase [EC:4.2.1.144 2.6.1.-]
K16423  (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103]
K16436  dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose/dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose/dTDP-2,6-dideoxy-D-kanosamine transaminase [EC:2.6.1.- 2.6.1.106]
K16903  L-tryptophan---pyruvate aminotransferase [EC:2.6.1.99]
K18653  3-dehydro-glucose-6-phosphate---glutamate transaminase [EC:2.6.1.104]
K19549  bacilysin biosynthesis transaminase BacF [EC:2.6.1.-]
K19562  bifunctional dethiobiotin synthetase / adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:6.3.3.3 2.6.1.62]
K19744  L-arginine dehydrogenase [EC:1.4.1.25]
K19746  D-arginine dehydrogenase [EC:1.4.99.6]
K19854  dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase [EC:2.6.1.89]
K20428  dTDP-4-amino-4,6-dideoxy-D-glucose transaminase [EC:2.6.1.33]
K20429  dTDP-4-amino-4,6-dideoxy-D-glucose transaminase [EC:2.6.1.33]
K20567  neamine transaminase / neomycin C transaminase [EC:2.6.1.93 2.6.1.95]
K20568  neamine transaminase / 2'-deamino-2'-hydroxyneamine transaminase [EC:2.6.1.93 2.6.1.94]
K20572  aminotransferase [EC:2.6.1.-]
K20591  pyridoxal phosphate-dependent aminotransferase [EC:2.6.1.-]
K20596  JI-20A/JI-20Ba transaminase [EC:2.6.1.-]
K20597  JI-20B transaminase / epimerase [EC:2.6.1.-]
K20680  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase [EC:2.6.1.90]
K21328  dTDP-4-amino-4,6-dideoxy-D-glucose/dTDP-4-amino-2,4-dideoxy-beta-L-xylose transaminase [EC:2.6.1.33 2.6.1.-]
K21346  methionine transaminase [EC:2.6.1.88]
K21639  L-arginine oxidase [EC:1.4.3.25]
K22457  asparagine---oxo-acid transaminase [EC:2.6.1.14]
K22598  8-demethyl-8-aminoriboflavin-5'-phosphate synthase [EC:2.6.1.114]
K24250  dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase [EC:2.6.1.89]
K24302  UDP-N-acetylbacillosamine transaminase [EC:2.6.1.34]
K25571  beta-alanine---2-oxoglutarate transaminase [EC:2.6.1.120]

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