KEGG   REACTION: R10794
Entry
R10794                      Reaction                               
Name
monacolin L acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
Definition
Monacolin L acid + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> Monacolin J acid + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C20853 + C00007 + C03024 <=> C20854 + C03161 + C00001
Reaction class
RC00661  C20853_C20854
Enzyme
1.14.14.125
Pathway
rn00997  Biosynthesis of various other secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00893  Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
Orthology
K20980  dihydromonacolin L/monacolin L hydroxylase [EC:1.14.14.124 1.14.14.125]
Other DBs
RHEA: 29602
LinkDB

KEGG   RCLASS: RC00661
Entry
RC00661                     RClass                                 
Definition
C1x-C1y:*-O1a:C1x+C1y-C1x+C1y
Reactant pair
C00148_C19706    C00280_C05284    C00280_C05296
C00410_C03747    C00410_C05498    C00410_C19726
C00477_C16495    C00535_C05291    C00695_C04483
C00735_C05488    C00808_C03448    C00809_C22610
C00859_C03579    C00951_C05141    C01078_C04397
C01176_C05497    C01433_C06071    C01512_C11636
C02046_C03325    C02140_C03205    C02528_C03990
C03990_C15515    C03990_C15517    C05487_C05489
C06231_C16432    C08616_C21821    C11864_C11868
C11898_C20151    C15485_C15502    C15500_C15501
C15787_C15788    C15793_C15794    C15801_C15802
C15802_C15803    C19678_C22049    C19678_C22051
C19829_C20715    C20403_C20404    C20715_C20716
C20834_C21978    C20853_C20854    C22436_C22437
C22447_C22448
 » show all
Related class
Reaction
R01842 R02214 R02218 R02503 R02725 R02843 R03008 R03089
R03218 R03329 R03556 R03812 R03818 R03851 R03978 R04850
R05832 R06338 R07186 R07187 R07203 R07206 R07220 R07450
R07467 R07470 R07474 R08050 R08135 R09572 R09587 R09867
R10157 R10540 R10591 R10794 R11976 R12177 R12266 R12273
R12832 R12848 R13092
Enzyme
1.14.11.7       1.14.11.11      1.14.11.13      1.14.11.25      
1.14.11.28      1.14.11.35      1.14.11.55      1.14.11.-       
1.14.13.146     1.14.14.1       1.14.14.57      1.14.14.64      
1.14.14.85      1.14.14.120     1.14.14.121     1.14.14.125     
1.14.14.138     1.14.14.168     1.14.14.170     1.14.14.179     
1.14.14.-       1.14.15.1       1.14.15.4       1.14.15.8       
1.14.99.14      1.14.99.61      1.14.-.-
Pathway
rn00140  Steroid hormone biosynthesis
rn00260  Glycine, serine and threonine metabolism
rn00902  Monoterpenoid biosynthesis
rn00904  Diterpenoid biosynthesis
rn00905  Brassinosteroid biosynthesis
rn00907  Pinene, camphor and geraniol degradation
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00981  Insect hormone biosynthesis
rn00996  Biosynthesis of various alkaloids
rn00997  Biosynthesis of various other secondary metabolites
rn00998  Biosynthesis of various antibiotics
rn00999  Biosynthesis of various plant secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
K04125  gibberellin 2beta-dioxygenase [EC:1.14.11.13]
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
K09590  brassinosteroid 6-oxygenase [EC:1.14.14.179]
K10674  ectoine hydroxylase [EC:1.14.11.55]
K10722  ecdysteroid 2-hydroxylase [EC:1.14.-.-]
K12640  brassinosteroid 6-oxygenase / brassinolide synthase [EC:1.14.14.179 1.14.14.180]
K12692  hyoscyamine (6S)-dioxygenase / 6beta-hydroxyhyoscyamine epoxidase [EC:1.14.11.11 1.14.20.13]
K18054  2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase [EC:1.14.11.24 1.14.11.25]
K18056  1-deoxypentalenic acid 11beta-hydroxylase [EC:1.14.11.35]
K20512  taxoid 14beta-hydroxylase [EC:1.14.13.146]
K20545  dammarenediol 12-hydroxylase [EC:1.14.14.120]
K20546  protopanaxadiol 6-hydroxylase [EC:1.14.14.121]
K20623  typhasterol/6-deoxotyphasterol 2alpha-hydroxylase
K20980  dihydromonacolin L/monacolin L hydroxylase [EC:1.14.14.124 1.14.14.125]
K21114  steroid 15beta-monooxygenase [EC:1.14.15.8]
K21569  camphor 5-monooxygenase [EC:1.14.15.1]
K21570  putidaredoxin---NAD+ reductase [EC:1.18.1.5]
K22997  cyclooctat-9-en-7-ol 5-monooxygenase [EC:1.14.99.61]
K23276  7-deoxyloganate 7-hydroxylase [EC:1.14.14.85]
K25488  11-carbonyl-20beta-hydroxycucurbitadienol 2-hydroxylase [EC:1.14.14.-]
K25492  22,26-dihydroxycholesterol 16alpha-hydroxylase [EC:1.14.11.-]
K25959  brassinosteroid 6-oxygenase / brassinolide synthase [EC:1.14.14.179 1.14.14.180]
K26398  putidaredoxin

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