KEGG   PATHWAY: msam04070
Entry
msam04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Micropterus salmoides (largemouth bass)
Class
Environmental Information Processing; Signal transduction
Pathway map
msam04070  Phosphatidylinositol signaling system
msam04070

Organism
Micropterus salmoides (largemouth bass) [GN:msam]
Gene
119882796  [KO:K00901] [EC:2.7.1.107]
119882859  calm3a; calmodulin 3a (phosphorylase kinase, delta) isoform X1 [KO:K02183]
119883006  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
119883088  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
119883529  [KO:K05857] [EC:3.1.4.11]
119883579  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
119883585  itpkcb; LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
119884309  [KO:K19801] [EC:2.7.1.67]
119884419  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
119884431  [KO:K00889] [EC:2.7.1.68]
119885088  [KO:K00901] [EC:2.7.1.107]
119885594  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
119885612  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
119885618  [KO:K04958]
119885675  mtmr14; myotubularin-related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
119885838  [KO:K00920] [EC:2.7.1.149]
119885905  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
119885962  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
119886007  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
119886032  dgkab; diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
119886042  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
119886349  [KO:K02183]
119886455  [KO:K04958]
119886474  [KO:K07756] [EC:2.7.4.21]
119886483  [KO:K04958]
119887750  [KO:K00901] [EC:2.7.1.107]
119888318  mtmr7a; myotubularin-related protein 7a [KO:K18083] [EC:3.1.3.64 3.1.3.95]
119888322  si:ch73-22a13.3; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
119888523  ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
119888846  inppl1b; inositol polyphosphate phosphatase-like 1b isoform X1 [KO:K15909] [EC:3.1.3.86]
119888974  [KO:K00901] [EC:2.7.1.107]
119889216  si:ch73-374l24.1; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
119890067  [KO:K02183]
119890281  [KO:K13024] [EC:2.7.4.24]
119891082  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
119891271  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
119891304  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
119891547  [KO:K02649]
119891672  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
119892032  cds1; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
119892198  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b isoform X1 [KO:K00888] [EC:2.7.1.67]
119892450  inpp5l; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
119893087  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
119893131  calml4b; calmodulin-like protein 4 [KO:K02183]
119893177  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
119893420  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
119893498  [KO:K05859] [EC:3.1.4.11]
119893637  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
119893822  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
119894203  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
119894204  [KO:K05861] [EC:3.1.4.11]
119895026  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
119895128  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
119895288  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
119895672  mtmr2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
119895815  itpkca; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
119896911  [KO:K21797] [EC:3.1.3.-]
119897050  dgkb; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
119897295  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
119897369  [KO:K01099] [EC:3.1.3.36]
119897496  prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
119897616  [KO:K00889] [EC:2.7.1.68]
119898239  [KO:K19801] [EC:2.7.1.67]
119898429  [KO:K15759] [EC:3.1.3.7]
119898457  [KO:K05861] [EC:3.1.4.11]
119898769  [KO:K19662] [EC:2.7.11.13]
119898871  inpp4b; LOW QUALITY PROTEIN: type II inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
119899340  [KO:K02677] [EC:2.7.11.13]
119899508  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
119899665  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
119899730  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
119899763  [KO:K00920] [EC:2.7.1.149]
119899814  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
119900121  [KO:K00888] [EC:2.7.1.67]
119900224  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
119900255  [KO:K01116] [EC:3.1.4.11]
119900335  [KO:K00922] [EC:2.7.1.153]
119900503  [KO:K02649]
119900707  [KO:K00901] [EC:2.7.1.107]
119900947  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
119901162  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
119901556  [KO:K13084] [EC:3.1.3.78]
119901743  pip4p1a; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A [KO:K13084] [EC:3.1.3.78]
119902193  [KO:K00889] [EC:2.7.1.68]
119902234  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
119902325  [KO:K00922] [EC:2.7.1.153]
119902368  [KO:K02649]
119902482  [KO:K05857] [EC:3.1.4.11]
119902579  bpnt2; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
119902759  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
119903805  [KO:K05857] [EC:3.1.4.11]
119903821  [KO:K02183]
119904285  inpp4aa; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
119904552  [KO:K00901] [EC:2.7.1.107]
119904556  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
119904580  dgkh; LOW QUALITY PROTEIN: diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
119905067  [KO:K01109] [EC:3.1.3.66]
119905085  itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
119905105  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
119905196  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
119905411  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
119905617  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
119906888  [KO:K19801] [EC:2.7.1.67]
119907092  sacm1la; phosphatidylinositol-3-phosphatase SAC1-A [KO:K21797] [EC:3.1.3.-]
119907514  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
119907889  [KO:K00889] [EC:2.7.1.68]
119908394  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
119908463  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
119908521  [KO:K05858] [EC:3.1.4.11]
119908641  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
119908913  [KO:K05858] [EC:3.1.4.11]
119909333  calm1b; calmodulin-1b [KO:K02183]
119909805  calm1a; calmodulin-1a [KO:K02183]
119910030  itpk1b; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
119910244  [KO:K05857] [EC:3.1.4.11]
119910354  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
119910939  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
119911009  [KO:K00911] [EC:2.7.1.127]
119911758  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
119911817  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
119912014  [KO:K01092] [EC:3.1.3.25]
119912023  [KO:K01092] [EC:3.1.3.25]
119912099  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
119912102  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
119912375  si:dkey-172j4.3; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
119912407  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
119912986  [KO:K01109] [EC:3.1.3.66]
119913171  [KO:K13084] [EC:3.1.3.78]
119913412  [KO:K05858] [EC:3.1.4.11]
119914041  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
119914216  pi4kaa; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
119914911  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a [KO:K00889] [EC:2.7.1.68]
119915599  ipmkb; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
119915637  [KO:K05857] [EC:3.1.4.11]
119915647  [KO:K05857] [EC:3.1.4.11]
119915776  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
119917190  ptena; phosphatase and tensin homolog A [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
119917210  [KO:K01106] [EC:3.1.3.56]
119917346  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
119917396  [KO:K02183]
119917416  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
119918081  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
msam04020  Calcium signaling pathway
msam04144  Endocytosis
msam04510  Focal adhesion
KO pathway
ko04070   

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