KEGG   PATHWAY: obi00230
Entry
obi00230                    Pathway                                
Name
Purine metabolism - Octopus bimaculoides (California two-spot octopus)
Class
Metabolism; Nucleotide metabolism
Pathway map
obi00230  Purine metabolism
obi00230

Module
obi_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:obi00230]
obi_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:obi00230]
obi_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:obi00230]
obi_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:obi00230]
obi_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:obi00230]
Other DBs
GO: 0006163 0042278
Organism
Octopus bimaculoides (California two-spot octopus) [GN:obi]
Gene
106875169  ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
106867761  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
106881854  ADP-sugar pyrophosphatase [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
106876411  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
106870409  phosphopentomutase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
106875582  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
106876546  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
106876245  trifunctional purine biosynthetic protein adenosine-3 isoform X1 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
106879080  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
106881666  bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase [KO:K01587] [EC:4.1.1.21 6.3.2.6]
106884423  adenylosuccinate lyase isoform X1 [KO:K01756] [EC:4.3.2.2]
106874801  bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
106878369  adenine phosphoribosyltransferase isoform X1 [KO:K00759] [EC:2.4.2.7]
106874234  trifunctional nucleotide phosphoesterase protein YfkN [KO:K01081] [EC:3.1.3.5]
106879215  cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
106881220  cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
106871337  snake venom 5'-nucleotidase [KO:K19970] [EC:3.1.3.5]
106870021  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
106868149  purine nucleoside phosphorylase LACC1 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
106871918  hypoxanthine-guanine phosphoribosyltransferase isoform X1 [KO:K00760] [EC:2.4.2.8]
106870430  inosine-5'-monophosphate dehydrogenase 1b isoform X1 [KO:K00088] [EC:1.1.1.205]
106867397  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
106875880  nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
106876202  nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
106882130  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
106867518  adenylate kinase 9 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
106876002  ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
106870165  soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
106874302  ectonucleoside triphosphate diphosphohydrolase 7 isoform X1 [KO:K12305] [EC:3.6.1.6]
106877907  ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
106869713  U8 snoRNA-decapping enzyme [KO:K16855] [EC:3.6.1.62 3.6.1.64]
106870217  inosine triphosphate pyrophosphatase isoform X1 [KO:K01519] [EC:3.6.1.66]
106872785  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X2 [KO:K01518] [EC:3.6.1.17]
106877610  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
106876869  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
106875355  GMP reductase 2 [KO:K00364] [EC:1.7.1.7]
106877796  guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
106875815  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
106881801  ribonucleoside-diphosphate reductase subunit M2 B isoform X1 [KO:K10808] [EC:1.17.4.1]
106867346  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
106876398  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [KO:K21138] [EC:3.1.7.2]
106868905  uncharacterized protein LOC106868905 [KO:K08041] [EC:4.6.1.1]
106882760  adenylate cyclase type 6 [KO:K08045] [EC:4.6.1.1]
106869877  guanylate cyclase soluble subunit alpha-2 [KO:K12318] [EC:4.6.1.2]
106878947  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
106868455  retinal guanylyl cyclase 2 isoform X1 [KO:K12322] [EC:4.6.1.2]
106867808  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
106867807  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
106869747  soluble guanylate cyclase 88E isoform X2 [KO:K01769] [EC:4.6.1.2]
106880009  soluble guanylate cyclase 88E isoform X1 [KO:K01769] [EC:4.6.1.2]
106880000  soluble guanylate cyclase 88E [KO:K01769] [EC:4.6.1.2]
106875208  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X6 [KO:K13755] [EC:3.1.4.17]
106877721  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1 [KO:K18283] [EC:3.1.4.17]
106871093  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A isoform X1 [KO:K19021] [EC:3.1.4.17]
106876356  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
106877860  cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13763] [EC:3.1.4.35]
106877861  cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13763] [EC:3.1.4.35]
106877862  cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13763] [EC:3.1.4.35]
106867143  cGMP-specific 3',5'-cyclic phosphodiesterase [KO:K13763] [EC:3.1.4.35]
106872352  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13763] [EC:3.1.4.35]
106868015  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
106878801  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
106869668  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
106884049  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
106879863  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
106880920  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
106874804  AMP deaminase 2 isoform X1 [KO:K01490] [EC:3.5.4.6]
106876500  AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
106880614  uncharacterized protein LOC106880614 isoform X1 [KO:K00856] [EC:2.7.1.20]
106879416  uncharacterized protein LOC106879416 [KO:K00856] [EC:2.7.1.20]
106883941  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
106873892  adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
106883940  adenylate kinase 2, mitochondrial [KO:K00939] [EC:2.7.4.3]
106872597  uncharacterized protein LOC106872597 isoform X1 [KO:K00939] [EC:2.7.4.3]
106877034  adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
106877265  adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
106877369  adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
106874656  GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
106883627  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
106867760  cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
106872159  high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X1 [KO:K18436] [EC:3.1.4.53]
106876564  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
106875650  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase [KO:K13811] [EC:2.7.7.4 2.7.1.25]
106883556  allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
obi00030  Pentose phosphate pathway
obi00220  Arginine biosynthesis
obi00250  Alanine, aspartate and glutamate metabolism
obi00260  Glycine, serine and threonine metabolism
obi00340  Histidine metabolism
obi00630  Glyoxylate and dicarboxylate metabolism
obi00730  Thiamine metabolism
obi00740  Riboflavin metabolism
obi00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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