KEGG   PATHWAY: caua04142
Entry
caua04142                   Pathway                                
Name
Lysosome - Carassius auratus (goldfish)
Description
Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy.
Class
Cellular Processes; Transport and catabolism
Pathway map
caua04142  Lysosome
caua04142

Other DBs
GO: 0005764
Organism
Carassius auratus (goldfish) [GN:caua]
Gene
113054119  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
113066126  V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
113092737  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
113113359  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
113048928  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
113043417  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
113097524  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
113110385  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
113046924  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
113091437  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
113051481  V-type proton ATPase subunit d 1 [KO:K02146]
113106035  V-type proton ATPase subunit d 1-like [KO:K02146]
113045524  V-type proton ATPase subunit H-like isoform X1 [KO:K02144]
113045731  V-type proton ATPase subunit H-like isoform X1 [KO:K02144]
113117966  V-type proton ATPase subunit H isoform X1 [KO:K02144]
113068698  atp6ap1; V-type proton ATPase subunit S1 [KO:K03662]
113070511  V-type proton ATPase subunit S1-like [KO:K03662]
113065509  V-type proton ATPase subunit S1-like [KO:K03662]
113092687  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
113042016  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
113043615  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
113046904  V-type proton ATPase 16 kDa proteolipid subunit-like [KO:K02155]
113118774  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
113038256  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
113045531  V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
113061865  dmX-like protein 2 isoform X1 [KO:K24155]
113052694  dmX-like protein 1 isoform X1 [KO:K24155]
113052791  dmX-like protein 1 isoform X1 [KO:K24155]
113118577  dmX-like protein 2 isoform X1 [KO:K24155]
113039063  wdr7; WD repeat-containing protein 7 isoform X1 [KO:K24738]
113068561  nuclear receptor coactivator 7-like [KO:K25442]
113120555  nuclear receptor coactivator 7-like isoform X1 [KO:K25442]
113095748  oxidation resistance protein 1-like [KO:K25442]
113117497  oxidation resistance protein 1-like isoform X1 [KO:K25442]
113106308  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
113051376  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
113104924  ctsa; lysosomal protective protein isoform X1 [KO:K13289] [EC:3.4.16.5]
113060627  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
113068580  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
113117245  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
113117368  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
113114714  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
113058764  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
113058774  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
113047624  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
113061519  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
113046815  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
113118288  cathepsin D [KO:K01379] [EC:3.4.23.5]
113066553  cathepsin E-A-like isoform X1 [KO:K01382] [EC:3.4.23.34]
113113727  cathepsin F-like [KO:K01373] [EC:3.4.22.41]
113057676  cathepsin F-like [KO:K01373] [EC:3.4.22.41]
113091663  pro-cathepsin H-like [KO:K01366] [EC:3.4.22.16]
113061626  pro-cathepsin H-like [KO:K01366] [EC:3.4.22.16]
113116115  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
113059151  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
113040547  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113075839  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113048924  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113049203  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113077942  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113078901  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113084968  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113064852  cathepsin L1-like isoform X1 [KO:K01365] [EC:3.4.22.15]
113117520  cathepsin L1-like isoform X1 [KO:K01365] [EC:3.4.22.15]
113091350  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
113113985  cathepsin O-like [KO:K01374] [EC:3.4.22.42]
113114139  cathepsin O-like [KO:K01374] [EC:3.4.22.42]
113082042  cathepsin O-like isoform X1 [KO:K01374] [EC:3.4.22.42]
113099544  cathepsin O-like [KO:K01374] [EC:3.4.22.42]
113119713  cathepsin L1-like [KO:K01368] [EC:3.4.22.27]
113119760  cathepsin L1-like [KO:K01368] [EC:3.4.22.27]
113062485  cathepsin L1-like [KO:K01368] [EC:3.4.22.27]
113116109  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113116110  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113116111  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113116112  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113116113  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113059153  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113059154  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
113050267  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
113045276  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
113105100  cathepsin Z-like isoform X1 [KO:K08568] [EC:3.4.18.1]
113112495  legumain-like [KO:K01369] [EC:3.4.22.34]
113092633  legumain-like [KO:K01369] [EC:3.4.22.34]
113076631  legumain-like [KO:K01369] [EC:3.4.22.34]
113056777  legumain-like [KO:K01369] [EC:3.4.22.34]
113046765  legumain-like [KO:K01369] [EC:3.4.22.34]
113060588  LOW QUALITY PROTEIN: tripeptidyl-peptidase 1-like [KO:K01279] [EC:3.4.14.9]
113069081  tripeptidyl-peptidase 1-like [KO:K01279] [EC:3.4.14.9]
113117469  tripeptidyl-peptidase 1-like [KO:K01279] [EC:3.4.14.9]
113075390  alpha-galactosidase A-like [KO:K01189] [EC:3.2.1.22]
113114125  alpha-galactosidase A-like [KO:K01189] [EC:3.2.1.22]
113081207  alpha-galactosidase A-like [KO:K01189] [EC:3.2.1.22]
113062583  glb1; beta-galactosidase [KO:K12309] [EC:3.2.1.23]
113094728  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
113044520  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
113046664  gaa; lysosomal alpha-glucosidase [KO:K12316] [EC:3.2.1.20]
113116327  gba; glucosylceramidase [KO:K01201] [EC:3.2.1.45]
113067964  idua; alpha-L-iduronidase [KO:K01217] [EC:3.2.1.76]
113048520  alpha-N-acetylgalactosaminidase-like [KO:K01204] [EC:3.2.1.49]
113048521  alpha-N-acetylgalactosaminidase-like [KO:K01204] [EC:3.2.1.49]
113064738  alpha-N-acetylgalactosaminidase-like [KO:K01204] [EC:3.2.1.49]
113042577  alpha-N-acetylglucosaminidase-like [KO:K01205] [EC:3.2.1.50]
113084861  alpha-N-acetylglucosaminidase-like [KO:K01205] [EC:3.2.1.50]
113121250  galactocerebrosidase [KO:K01202] [EC:3.2.1.46]
113117428  galactocerebrosidase-like [KO:K01202] [EC:3.2.1.46]
113068057  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
113070710  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
113070767  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
113091840  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
113119478  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
113119479  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
113060851  fuca2; plasma alpha-L-fucosidase [KO:K01206] [EC:3.2.1.51]
113075961  beta-hexosaminidase subunit beta-like [KO:K12373] [EC:3.2.1.52]
113067062  beta-hexosaminidase subunit alpha-like [KO:K12373] [EC:3.2.1.52]
113093900  beta-hexosaminidase subunit beta-like isoform X1 [KO:K12373] [EC:3.2.1.52]
113049526  beta-hexosaminidase subunit beta-like isoform X1 [KO:K12373] [EC:3.2.1.52]
113043549  beta-hexosaminidase subunit alpha-like isoform X1 [KO:K12373] [EC:3.2.1.52]
113057098  manba; beta-mannosidase [KO:K01192] [EC:3.2.1.25]
113055377  man2b1; lysosomal alpha-mannosidase [KO:K12311] [EC:3.2.1.24]
113119511  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
113119512  sialidase-1-like isoform X1 [KO:K01186] [EC:3.2.1.18]
113090783  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
113090792  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
113090830  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
113106732  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
113066979  hyaluronidase-like [KO:K01197] [EC:3.2.1.35]
113066980  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
113093962  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
113093966  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
113094804  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
113107975  hyaluronidase-3-like [KO:K01197] [EC:3.2.1.35]
113078402  hyaluronidase-3-like [KO:K01197] [EC:3.2.1.35]
113043436  hyaluronidase-5-like [KO:K01197] [EC:3.2.1.35]
113043437  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
113050165  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
113050167  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
113079540  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
113064736  hyaluronidase-2-like isoform X1 [KO:K01197] [EC:3.2.1.35]
113104044  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
113040233  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
113073071  arylsulfatase A-like [KO:K01134] [EC:3.1.6.8]
113118177  arylsulfatase A-like isoform X1 [KO:K01134] [EC:3.1.6.8]
113080754  arylsulfatase B-like [KO:K01135] [EC:3.1.6.12]
113090446  arylsulfatase B-like [KO:K01135] [EC:3.1.6.12]
113112101  arylsulfatase G-like isoform X1 [KO:K12381] [EC:3.1.6.-]
113106343  galns; LOW QUALITY PROTEIN: N-acetylgalactosamine-6-sulfatase [KO:K01132] [EC:3.1.6.4]
113047860  N-acetylglucosamine-6-sulfatase-like isoform X1 [KO:K01137] [EC:3.1.6.14]
113048503  N-acetylglucosamine-6-sulfatase-like isoform X1 [KO:K01137] [EC:3.1.6.14]
113054636  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
113054691  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
113067919  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
113110341  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
113064286  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
113113609  ids; iduronate 2-sulfatase [KO:K01136] [EC:3.1.6.13]
113064755  sgsh; N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
113056219  lipa; lysosomal acid lipase/cholesteryl ester hydrolase isoform X1 [KO:K01052] [EC:3.1.1.13]
113111790  lysosomal acid lipase/cholesteryl ester hydrolase-like [KO:K01052] [EC:3.1.1.13]
113043723  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
113097555  group XV phospholipase A2-like [KO:K06129] [EC:3.1.1.5]
113069363  dnase2b; deoxyribonuclease-2-beta isoform X1 [KO:K01158] [EC:3.1.22.1]
113115741  dnase2; deoxyribonuclease-2-alpha [KO:K01158] [EC:3.1.22.1]
113051450  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
113051633  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
113106112  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
113091952  tartrate-resistant acid phosphatase type 5-like isoform X1 [KO:K14379] [EC:3.1.3.2]
113042555  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
113080787  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
113050892  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
113092440  LOW QUALITY PROTEIN: sphingomyelin phosphodiesterase-like [KO:K12350] [EC:3.1.4.12]
113109800  sphingomyelin phosphodiesterase-like [KO:K12350] [EC:3.1.4.12]
113107462  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
113113993  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
113114201  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
113044164  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
113080950  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
113057920  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
113114143  aga; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase [KO:K01444] [EC:3.5.1.26]
113056998  N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase- like isoform X1 [KO:K01444] [EC:3.5.1.26]
113113018  prosaposin-like isoform X1 [KO:K12382]
113057280  prosaposin-like isoform X1 [KO:K12382]
113110407  prosaposin-like [KO:K12382]
113114261  ganglioside GM2 activator-like [KO:K12383]
113114533  ganglioside GM2 activator-like [KO:K12383]
113119295  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
113061057  ppt2; lysosomal thioesterase PPT2 isoform X1 [KO:K01074] [EC:3.1.2.22]
113062121  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
113114978  lysosomal thioesterase PPT2-like [KO:K01074] [EC:3.1.2.22]
113108835  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
113109274  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
113044686  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
113057877  lysosome-associated membrane glycoprotein 2-like isoform X1 [KO:K06528]
113057899  lysosome-associated membrane glycoprotein 2-like [KO:K06528]
113086720  lamp1; lysosome-associated membrane glycoprotein 1 [KO:K06528]
113053097  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
113039786  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
113065198  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
113052258  macrosialin-like [KO:K06501]
113105584  macrosialin-like [KO:K06501]
113041434  cd63; CD63 antigen [KO:K06497]
113065585  CD63 antigen-like [KO:K06497]
113065613  CD63 antigen-like [KO:K06497]
113049645  lysosome membrane protein 2-like isoform X1 [KO:K12384]
113097223  lysosome membrane protein 2-like [KO:K12384]
113080915  lysosome membrane protein 2-like [KO:K12384]
113082897  lysosome membrane protein 2-like [KO:K12384]
113064477  lysosome membrane protein 2-like [KO:K12384]
113064484  lysosome membrane protein 2-like [KO:K12384]
113064486  lysosome membrane protein 2-like [KO:K12384]
113064487  lysosome membrane protein 2-like [KO:K12384]
113064488  lysosome membrane protein 2-like [KO:K12384]
113039073  lysosome membrane protein 2-like [KO:K12384]
113039110  lysosome membrane protein 2-like [KO:K12384]
113045980  npc1; NPC intracellular cholesterol transporter 1 [KO:K12385]
113060543  NPC intracellular cholesterol transporter 2-like [KO:K13443]
113117115  NPC intracellular cholesterol transporter 2-like [KO:K13443]
113055146  cystinosin-like [KO:K12386]
113110755  cystinosin-like [KO:K12386]
113112672  sialin-like [KO:K12301]
113119293  sialin-like [KO:K12301]
113062122  sialin-like isoform X1 [KO:K12301]
113056939  sialin-like [KO:K12301]
113054923  natural resistance-associated macrophage protein 2-like [KO:K21398]
113068166  natural resistance-associated macrophage protein 2-like [KO:K21398]
113091833  lysosomal-associated transmembrane protein 4B-like [KO:K12387]
113092596  lysosomal-associated transmembrane protein 4A-like [KO:K12387]
113119459  lysosomal-associated transmembrane protein 4B-like [KO:K12387]
113120526  lysosomal-associated transmembrane protein 4A [KO:K12387]
113120527  lysosomal-associated transmembrane protein 4A [KO:K12387]
113049876  ATP-binding cassette sub-family A member 2-like isoform X1 [KO:K05642]
113091322  ATP-binding cassette sub-family A member 2-like isoform X1 [KO:K05642]
113095627  ATP-binding cassette sub-family B member 9-like [KO:K05656]
113079335  ATP-binding cassette sub-family B member 9-like [KO:K05656]
113120774  sialomucin core protein 24-like isoform X1 [KO:K06546]
113120925  sialomucin core protein 24-like isoform X1 [KO:K06546]
113063097  sialomucin core protein 24-like [KO:K06546]
113107450  entpd4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
113039676  ectonucleoside triphosphate diphosphohydrolase 4-like isoform X1 [KO:K12305] [EC:3.6.1.6]
113048105  sortilin-like isoform X1 [KO:K12388]
113093986  sortilin-like [KO:K12388]
113107569  sortilin-like [KO:K12388]
113107611  sortilin-like [KO:K12388]
113055362  sortilin-like [KO:K12388]
113062463  sortilin-like isoform X1 [KO:K12388]
113110903  sortilin [KO:K12388]
113078084  cln3; battenin [KO:K12389]
113109038  cln5; ceroid-lipofuscinosis neuronal protein 5 [KO:K12390]
113056097  major facilitator superfamily domain-containing protein 8 isoform X1 [KO:K12307]
113038529  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
113039767  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
113111853  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
113044152  hgsnat; heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
113057486  heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
113106107  heparan-alpha-glucosaminide N-acetyltransferase-like [KO:K10532] [EC:2.3.1.78]
113094536  sumf1; formylglycine-generating enzyme isoform X1 [KO:K13444] [EC:1.8.3.7]
113048152  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like isoform X1 [KO:K08239] [EC:2.7.8.17]
113062700  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta [KO:K08239] [EC:2.7.8.17]
113092776  gnptg; N-acetylglucosamine-1-phosphotransferase subunit gamma [KO:K10087]
113115929  N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like [KO:K01125] [EC:3.1.4.45]
113059303  N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like [KO:K01125] [EC:3.1.4.45]
113120488  LOW QUALITY PROTEIN: cation-independent mannose-6-phosphate receptor-like [KO:K06564]
113114827  cation-independent mannose-6-phosphate receptor-like [KO:K06564]
113060138  cation-dependent mannose-6-phosphate receptor-like [KO:K10089]
113116228  cation-dependent mannose-6-phosphate receptor-like [KO:K10089]
113044322  clathrin light chain A-like isoform X1 [KO:K04644]
113105697  clathrin light chain A-like isoform X1 [KO:K04644]
113113836  clathrin light chain B-like isoform X1 [KO:K04645]
113057621  clathrin light chain B-like isoform X1 [KO:K04645]
113054353  clathrin heavy chain 1-like isoform X1 [KO:K04646]
113097152  clathrin heavy chain 1-like isoform X1 [KO:K04646]
113115183  clathrin heavy chain 1-like isoform X1 [KO:K04646]
113058341  cltc; clathrin heavy chain 1 isoform X1 [KO:K04646]
113111802  clathrin heavy chain 1-like isoform X1 [KO:K04646]
113047282  AP-2 complex subunit alpha-2-like [KO:K12391]
113106443  AP-1 complex subunit gamma-1 isoform X1 [KO:K12391]
113119957  AP-1 complex subunit gamma-1-like [KO:K12391]
113044975  AP-1 complex subunit gamma-1-like [KO:K12391]
113051833  AP-1 complex subunit gamma-1-like [KO:K12391]
113049865  ap1b1; AP-1 complex subunit beta-1 isoform X1 [KO:K12392]
113091338  AP-1 complex subunit beta-1-like isoform X1 [KO:K12392]
113074985  AP-1 complex subunit mu-1-like [KO:K12393]
113050504  AP-1 complex subunit mu-1-like isoform X1 [KO:K12393]
113045262  AP-1 complex subunit mu-1-like [KO:K12393]
113072330  AP-1 complex subunit mu-2 [KO:K12393]
113100862  AP-1 complex subunit mu-1-like [KO:K12393]
113111299  AP-1 complex subunit mu-1 [KO:K12393]
113112421  AP-1 complex subunit mu-1 [KO:K12393]
113041231  AP-1 complex subunit sigma-2 isoform X1 [KO:K12394]
113055162  AP-1 complex subunit sigma-2-like [KO:K12394]
113110622  AP-1 complex subunit sigma-2-like [KO:K12394]
113110778  AP-1 complex subunit sigma-2-like [KO:K12394]
113052060  AP-1 complex subunit sigma-1A [KO:K12394]
113065414  AP-1 complex subunit sigma-2 isoform X1 [KO:K12394]
113090436  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12394]
113105787  AP-1 complex subunit sigma-1A [KO:K12394]
113071073  AP-1 complex subunit sigma-2-like [KO:K12395]
113114036  AP-1 complex subunit sigma-3-like [KO:K12395]
113114723  AP-1 complex subunit sigma-3-like [KO:K12395]
113045330  AP-1 complex subunit sigma-3-like [KO:K12395]
113046218  AP-1 complex subunit sigma-3-like [KO:K12395]
113064994  AP-3 complex subunit delta-1-like isoform X1 [KO:K12396]
113040020  AP-3 complex subunit delta-1-like isoform X1 [KO:K12396]
113075115  AP-3 complex subunit beta-1-like [KO:K12397]
113043166  AP-3 complex subunit beta-2-like isoform X1 [KO:K12397]
113095292  AP-3 complex subunit beta-1-like [KO:K12397]
113085848  AP-3 complex subunit beta-2-like isoform X1 [KO:K12397]
113038986  AP-3 complex subunit beta-1-like isoform X1 [KO:K12397]
113074199  AP-3 complex subunit beta-1-like isoform X1 [KO:K12397]
113112551  AP-3 complex subunit mu-1 [KO:K12398]
113048946  AP-3 complex subunit mu-2 [KO:K12398]
113056974  AP-3 complex subunit mu-1-like [KO:K12398]
113081400  AP-3 complex subunit mu-1-like [KO:K12398]
113071728  AP-3 complex subunit mu-2-like [KO:K12398]
113066831  AP-3 complex subunit sigma-2 [KO:K12399]
113106916  AP-3 complex subunit sigma-1 isoform X1 [KO:K12399]
113043067  AP-3 complex subunit sigma-2-like [KO:K12399]
113085676  AP-3 complex subunit sigma-1-like [KO:K12399]
113042872  AP-4 complex subunit epsilon-1-like [KO:K12400]
113082813  AP-4 complex subunit epsilon-1-like [KO:K12400]
113041005  AP-4 complex subunit beta-1-like [KO:K12401]
113094048  AP-4 complex subunit beta-1-like [KO:K12401]
113093058  AP-4 complex subunit mu-1-like [KO:K12402]
113079420  LOW QUALITY PROTEIN: AP-4 complex subunit mu-1-like [KO:K12402]
113117552  ap4s1; AP-4 complex subunit sigma-1 [KO:K12403]
113054884  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
113054896  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
113067368  ADP-ribosylation factor-binding protein GGA3-like isoform X1 [KO:K12404]
113067855  ADP-ribosylation factor-binding protein GGA3-like isoform X1 [KO:K12404]
113050711  gga1; ADP-ribosylation factor-binding protein GGA1 [KO:K12404]
113097954  ADP-ribosylation factor-binding protein GGA3-like isoform X1 [KO:K12404]
113048469  mucolipin-1-like [KO:K04992]
113054976  mucolipin-1-like [KO:K04992]
113067769  mucolipin-1-like [KO:K04992]
113067857  mucolipin-1-like [KO:K04992]
113098192  mucolipin-1-like [KO:K04992]
113063893  mucolipin-1-like [KO:K04992]
113075113  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
113054306  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
113067808  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
113067811  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
113049846  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
113056264  uncharacterized protein LOC113056264 [KO:K19363]
113056975  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
113057135  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
113097629  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
113044801  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
113071528  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
113105402  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
Compound
C00002  ATP
C00008  ADP
C00159  D-Mannose
C00275  D-Mannose 6-phosphate
Reference
PMID:12628346
  Authors
Eskelinen EL, Tanaka Y, Saftig P
  Title
At the acidic edge: emerging functions for lysosomal membrane proteins.
  Journal
Trends Cell Biol 13:137-45 (2003)
DOI:10.1016/S0962-8924(03)00005-9
Reference
PMID:1883197
  Authors
Neufeld EF
  Title
Lysosomal storage diseases.
  Journal
Annu Rev Biochem 60:257-80 (1991)
DOI:10.1146/annurev.bi.60.070191.001353
Reference
PMID:2943218
  Authors
von Figura K, Hasilik A
  Title
Lysosomal enzymes and their receptors.
  Journal
Annu Rev Biochem 55:167-93 (1986)
DOI:10.1146/annurev.bi.55.070186.001123
Reference
PMID:15987739
  Authors
Janvier K, Bonifacino JS
  Title
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins.
  Journal
Mol Biol Cell 16:4231-42 (2005)
DOI:10.1091/mbc.E05-03-0213
Reference
PMID:18635948
  Authors
Vergarajauregui S, Puertollano R
  Title
Mucolipidosis type IV: the importance of functional lysosomes for efficient autophagy.
  Journal
Autophagy 4:832-4 (2008)
DOI:10.4161/auto.6567
Reference
PMID:34249946
  Authors
Jaskolka MC, Winkley SR, Kane PM
  Title
RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification.
  Journal
Front Cell Dev Biol 9:698190 (2021)
DOI:10.3389/fcell.2021.698190
Reference
PMID:34646033
  Authors
Majdoul S, Compton AA
  Title
Lessons in self-defence: inhibition of virus entry by intrinsic immunity.
  Journal
Nat Rev Immunol 10.1038/s41577-021-00626-8 (2021)
DOI:10.1038/s41577-021-00626-8
Related
pathway
caua00511  Other glycan degradation
caua00531  Glycosaminoglycan degradation
caua04130  SNARE interactions in vesicular transport
caua04140  Autophagy - animal
caua04144  Endocytosis
KO pathway
ko04142   
LinkDB

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