KEGG   PATHWAY: pki04141
Entry
pki04141                    Pathway                                
Name
Protein processing in endoplasmic reticulum - Paramormyrops kingsleyae
Description
The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
pki04141  Protein processing in endoplasmic reticulum
pki04141

Other DBs
GO: 0030433 0034976
Organism
Paramormyrops kingsleyae [GN:pki]
Gene
111837576  protein transport protein Sec61 subunit alpha-like 1 [KO:K10956]
111840604  protein transport protein Sec61 subunit alpha-like 1 [KO:K10956]
111845873  sec61b; protein transport protein Sec61 subunit beta [KO:K09481]
111837166  sec61g; protein transport protein Sec61 subunit gamma [KO:K07342]
111850484  sec62; translocation protein SEC62 isoform X1 [KO:K12275]
111856684  sec63; translocation protein SEC63 homolog isoform X1 [KO:K09540]
111832900  rpn1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 [KO:K12666]
111840978  rpn2; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X1 [KO:K12667]
111846226  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1 [KO:K12668]
111857164  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
111853729  ddost; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [KO:K12670]
111857844  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B isoform X1 [KO:K07151] [EC:2.4.99.18]
111849584  stt3a; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
111846954  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B-like isoform X1 [KO:K07151] [EC:2.4.99.18]
111846302  magt1; magnesium transporter protein 1 [KO:K19478]
111855207  magnesium transporter protein 1-like isoform X1 [KO:K19478]
111853627  tusc3; tumor suppressor candidate 3 isoform X1 [KO:K19478]
111848703  ostc; oligosaccharyltransferase complex subunit OSTC [KO:K26501]
111834515  tmem258; transmembrane protein 258 [KO:K26502]
111837272  mogs; mannosyl-oligosaccharide glucosidase isoform X1 [KO:K01228] [EC:3.2.1.106]
111838516  ckap4; cytoskeleton-associated protein 4 [KO:K13999]
111835724  rrbp1; ribosome-binding protein 1 isoform X1 [KO:K14000]
111835058  sil1; nucleotide exchange factor SIL1 [KO:K14001]
111855810  hyou1; hypoxia up-regulated protein 1 [KO:K09486]
111843454  78 kDa glucose-regulated protein-like [KO:K09490] [EC:3.6.4.10]
111842682  hspa5; 78 kDa glucose-regulated protein [KO:K09490] [EC:3.6.4.10]
111840666  dnaJ homolog subfamily B member 11-like [KO:K09517]
111857203  dnaJ homolog subfamily B member 11-like [KO:K09517]
111858966  dnajc1; dnaJ homolog subfamily C member 1 [KO:K09521]
111834145  dnajc3; dnaJ homolog subfamily C member 3 [KO:K09523]
111854473  dnaJ homolog subfamily C member 3-like isoform X1 [KO:K09523]
111838607  dnaJ homolog subfamily C member 10-like isoform X1 [KO:K09530] [EC:1.8.4.-]
111834451  dnaJ homolog subfamily C member 10-like isoform X1 [KO:K09530] [EC:1.8.4.-]
111847031  endoplasmin-like isoform X1 [KO:K09487]
111844306  hsp90b1; endoplasmin [KO:K09487]
111852985  neutral alpha-glucosidase AB-like isoform X1 [KO:K05546] [EC:3.2.1.207]
111860858  neutral alpha-glucosidase AB-like isoform X1 [KO:K05546] [EC:3.2.1.207]
111842639  glucosidase 2 subunit beta-like [KO:K08288]
111849141  prkcsh; glucosidase 2 subunit beta [KO:K08288]
111846321  calnexin-like isoform X1 [KO:K08054]
111859880  canx; calnexin isoform X1 [KO:K08054]
111836475  protein disulfide-isomerase A3-like [KO:K08056] [EC:5.3.4.1]
111845058  pdia3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
111837920  protein disulfide-isomerase A3-like isoform X1 [KO:K08056] [EC:5.3.4.1]
111838389  protein disulfide-isomerase A3-like isoform X1 [KO:K08056] [EC:5.3.4.1]
111847590  calreticulin-like [KO:K08057]
111848972  calreticulin-like [KO:K08057]
111860325  calreticulin-like [KO:K08057]
111836163  man1a1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IA [KO:K01230] [EC:3.2.1.113]
111844543  mannosyl-oligosaccharide 1,2-alpha-mannosidase IA-like isoform X1 [KO:K01230] [EC:3.2.1.113]
111855689  mannosyl-oligosaccharide 1,2-alpha-mannosidase IB-like [KO:K01230] [EC:3.2.1.113]
111856873  man1a2; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB isoform X1 [KO:K01230] [EC:3.2.1.113]
111854001  endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase-like isoform X1 [KO:K23741] [EC:3.2.1.209]
111857531  man1b1; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase isoform X1 [KO:K23741] [EC:3.2.1.209]
111835081  lman2; vesicular integral-membrane protein VIP36 [KO:K10082]
111852601  lman1; protein ERGIC-53 [KO:K10080]
111838655  preb; prolactin regulatory element-binding protein isoform X1 [KO:K14003]
111847953  GTP-binding protein SAR1b [KO:K07953] [EC:3.6.5.-]
111841966  sar1a; GTP-binding protein SAR1a [KO:K07953] [EC:3.6.5.-]
111860856  GTP-binding protein SAR1b-like [KO:K07953] [EC:3.6.5.-]
111843610  sec13; protein SEC13 homolog isoform X1 [KO:K14004]
111835790  sec31a; protein transport protein Sec31A isoform X1 [KO:K14005]
111841959  protein transport protein Sec31A-like isoform X1 [KO:K14005]
111850829  sec23b; protein transport protein Sec23B isoform X1 [KO:K14006]
111855021  LOW QUALITY PROTEIN: protein transport protein Sec23A-like [KO:K14006]
111839404  protein transport protein Sec24C-like isoform X1 [KO:K14007]
111853158  protein transport protein Sec24D-like [KO:K14007]
111848378  protein transport protein Sec24C-like isoform X1 [KO:K14007]
111834715  sec24d; protein transport protein Sec24D isoform X1 [KO:K14007]
111835497  sec24b; protein transport protein Sec24B isoform X1 [KO:K14007]
111857580  protein transport protein Sec24C-like isoform X1 [KO:K14007]
111860855  sec24a; protein transport protein Sec24A isoform X1 [KO:K14007]
111847416  uggt1; UDP-glucose:glycoprotein glucosyltransferase 1 isoform X1 [KO:K11718] [EC:2.4.1.-]
111859683  UDP-glucose:glycoprotein glucosyltransferase 2-like isoform X1 [KO:K11718] [EC:2.4.1.-]
111840537  edem1; ER degradation-enhancing alpha-mannosidase-like protein 1 isoform X1 [KO:K10084]
111837011  edem2; ER degradation-enhancing alpha-mannosidase-like protein 2 [KO:K10085]
111860257  edem3; ER degradation-enhancing alpha-mannosidase-like protein 3 isoform X1 [KO:K10086]
111853977  ER degradation-enhancing alpha-mannosidase-like protein 3 [KO:K10086]
111832914  p4hb; protein disulfide-isomerase [KO:K09580] [EC:5.3.4.1]
111834009  pdia4; protein disulfide-isomerase A4 [KO:K09582] [EC:5.3.4.1]
111838610  dnaJ homolog subfamily C member 10-like [KO:K09584] [EC:5.3.4.1]
111855572  pdia6; protein disulfide-isomerase A6 [KO:K09584] [EC:5.3.4.1]
111840751  txndc5; thioredoxin domain-containing protein 5 isoform X1 [KO:K13984] [EC:5.3.4.1]
111836496  ero1a; ERO1-like protein alpha isoform X1 [KO:K10950] [EC:1.8.4.-]
111856368  ero1b; ERO1-like protein beta isoform X1 [KO:K10976] [EC:1.8.4.-]
111855095  os9; protein OS-9 isoform X1 [KO:K10088]
111853427  erlec1; endoplasmic reticulum lectin 1 isoform X1 [KO:K14008]
111858968  ssr1; translocon-associated protein subunit alpha isoform X1 [KO:K13249]
111861094  translocon-associated protein subunit alpha-like [KO:K13249]
111837917  ssr2; translocon-associated protein subunit beta isoform X1 [KO:K13250]
111833838  ssr3; translocon-associated protein subunit gamma [KO:K13251]
111855271  ssr4; translocon-associated protein subunit delta [KO:K04571]
111851634  bcap31; B-cell receptor-associated protein 31 [KO:K14009]
111834935  tram1; translocating chain-associated membrane protein 1 [KO:K14010]
111857357  translocating chain-associated membrane protein 1-like [KO:K14010]
111852229  derl1; derlin-1 isoform X1 [KO:K11519]
111854806  derl2; derlin-2 [KO:K13989]
111858710  derl3; derlin-3 isoform X1 [KO:K13989]
111849080  ubxn4; UBX domain-containing protein 4 [KO:K24348]
111853014  ubxn1; UBX domain-containing protein 1 isoform X1 [KO:K24348]
111837350  ubxn2a; UBX domain-containing protein 2A isoform X1 [KO:K24349]
111860415  ubxn6; UBX domain-containing protein 6 isoform X1 [KO:K14011]
111835926  ubxn8; UBX domain-containing protein 8 isoform X1 [KO:K24351]
111839597  nsfl1c; NSFL1 cofactor p47 [KO:K14012]
111839893  NSFL1 cofactor p47-like [KO:K14012]
111836501  svip; small VCP/p97-interacting protein [KO:K14014]
111849832  transitional endoplasmic reticulum ATPase-like [KO:K13525]
111856597  transitional endoplasmic reticulum ATPase isoform X1 [KO:K13525]
111840957  transitional endoplasmic reticulum ATPase-like isoform X1 [KO:K13525]
111838289  nuclear protein localization protein 4 homolog isoform X1 [KO:K14015]
111846618  nuclear protein localization protein 4 homolog [KO:K14015]
111856849  ufd1; ubiquitin recognition factor in ER-associated degradation protein 1 [KO:K14016]
111855675  heat shock cognate 71 kDa protein-like [KO:K03283]
111834334  heat shock 70 kDa protein [KO:K03283]
111855702  heat shock cognate 71 kDa protein [KO:K03283]
111833700  heat shock cognate 71 kDa protein-like [KO:K03283]
111844212  dnaJ homolog subfamily A member 1-like [KO:K09502]
111846437  dnaja2; dnaJ homolog subfamily A member 2 [KO:K09503]
111849653  dnaJ homolog subfamily A member 2-like [KO:K09503]
111840959  dnaJ homolog subfamily B member 1-like [KO:K09507]
111849231  dnaJ homolog subfamily B member 1-like isoform X1 [KO:K09507]
111840673  dnajb2; dnaJ homolog subfamily B member 2 isoform X1 [KO:K09508]
111852235  dnaJ homolog subfamily B member 6-like isoform X1 [KO:K09508]
111841928  dnajb12; dnaJ homolog subfamily B member 12 [KO:K09518]
111835922  dnaJ homolog subfamily C member 5-like [KO:K09525]
111834903  dnajc5b; dnaJ homolog subfamily C member 5B [KO:K09525]
111837143  dnajc5; dnaJ homolog subfamily C member 5 [KO:K09525]
111854020  dnajc5g; dnaJ homolog subfamily C member 5G isoform X1 [KO:K09525]
111844402  heat shock protein HSP 90-alpha isoform X1 [KO:K04079]
111852409  heat shock protein HSP 90-alpha-like isoform X1 [KO:K04079]
111852410  heat shock protein HSP 90-alpha 1 [KO:K04079]
111837696  hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
111851289  hsph1; heat shock protein 105 kDa [KO:K09485]
111844230  hspa4l; heat shock 70 kDa protein 4L isoform X1 [KO:K09485]
111857748  bag1; BAG family molecular chaperone regulator 1 [KO:K09555]
111836846  hspbp1; hsp70-binding protein 1 [KO:K09562]
111843684  alpha-crystallin A chain-like isoform X1 [KO:K09541]
111853127  cryaa; alpha-crystallin A chain [KO:K09541]
111844776  cryab; alpha-crystallin B chain isoform X1 [KO:K09542]
111858608  yod1; ubiquitin thioesterase OTU1 [KO:K13719] [EC:3.1.2.-]
111848727  plaa; phospholipase A-2-activating protein [KO:K14018]
111838466  UV excision repair protein RAD23 homolog B-like isoform X1 [KO:K10839]
111833512  UV excision repair protein RAD23 homolog A-like [KO:K10839]
111834239  UV excision repair protein RAD23 homolog B-like isoform X1 [KO:K10839]
111860379  UV excision repair protein RAD23 homolog B-like [KO:K10839]
111839300  ubqln1; ubiquilin-1 [KO:K04523]
111853487  ubqln4; ubiquilin-4 [KO:K04523]
111842759  ngly1; peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase isoform X1 [KO:K01456] [EC:3.5.1.52]
111838812  atxn3; ataxin-3 [KO:K11863] [EC:3.4.22.-]
111858906  ube4b; ubiquitin conjugation factor E4 B isoform X1 [KO:K10597] [EC:2.3.2.27]
111835392  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [KO:K08860] [EC:2.7.11.1]
111858978  eif2s1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
111838582  nfe2l2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638]
111835975  cyclic AMP-dependent transcription factor ATF-4-like [KO:K04374]
111845249  cyclic AMP-dependent transcription factor ATF-4-like [KO:K04374]
111835263  ddit3; DNA damage-inducible transcript 3 protein [KO:K04452]
111851660  apoptosis regulator Bcl-2-like [KO:K02161]
111845833  apoptosis regulator Bcl-2-like [KO:K02161]
111841038  atf6; cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1 [KO:K09054]
111840080  cyclic AMP-dependent transcription factor ATF-6 alpha-like [KO:K09054]
111842807  atf6b; cyclic AMP-dependent transcription factor ATF-6 beta isoform X1 [KO:K09049]
111836784  wolframin-like isoform X1 [KO:K14020]
111836210  wfs1; wolframin [KO:K14020]
111851928  mbtps1; membrane-bound transcription factor site-1 protease isoform X1 [KO:K08653] [EC:3.4.21.112]
111860977  mbtps2; membrane-bound transcription factor site-2 protease [KO:K07765] [EC:3.4.24.85]
111849892  X-box-binding protein 1-like [KO:K09027]
111845540  ern2; serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
111848220  ern1; serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
111847460  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
111848593  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
111835361  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
111858668  traf2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
111848885  mitogen-activated protein kinase kinase kinase 5-like [KO:K04426] [EC:2.7.11.25]
111843026  map3k5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
111833549  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
111850762  mitogen-activated protein kinase 9-like [KO:K04440] [EC:2.7.11.24]
111839372  mitogen-activated protein kinase 10-like isoform X1 [KO:K04440] [EC:2.7.11.24]
111850356  mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
111848368  mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
111852585  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
111855469  mitogen-activated protein kinase 9-like isoform X1 [KO:K04440] [EC:2.7.11.24]
111836931  apoptosis regulator BAX-like [KO:K02159]
111836833  bax; apoptosis regulator BAX isoform X1 [KO:K02159]
111851814  apoptosis regulator BAX-like isoform X1 [KO:K02159]
111844757  bak1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
111857887  calpain-1 catalytic subunit-like [KO:K01367] [EC:3.4.22.52]
111851624  calpain-1 catalytic subunit-like [KO:K01367] [EC:3.4.22.52]
111852380  calpain-1 catalytic subunit-like [KO:K01367] [EC:3.4.22.52]
111852307  calpain-1 catalytic subunit-like [KO:K01367] [EC:3.4.22.52]
111860100  calpain-1 catalytic subunit-like [KO:K01367] [EC:3.4.22.52]
111852308  calpain-2 catalytic subunit-like [KO:K03853] [EC:3.4.22.53]
111835677  calpain-2 catalytic subunit-like [KO:K03853] [EC:3.4.22.53]
111852340  calpain-2 catalytic subunit-like [KO:K03853] [EC:3.4.22.53]
111852381  calpain-2 catalytic subunit-like [KO:K03853] [EC:3.4.22.53]
111852382  calpain-2 catalytic subunit-like [KO:K03853] [EC:3.4.22.53]
111841738  calpain-2 catalytic subunit-like isoform X1 [KO:K03853] [EC:3.4.22.53]
111849511  E3 ubiquitin-protein ligase MARCH6-like isoform X1 [KO:K10661] [EC:2.3.2.27]
111835417  E3 ubiquitin-protein ligase MARCH6 isoform X1 [KO:K10661] [EC:2.3.2.27]
111843047  ube2j1; ubiquitin-conjugating enzyme E2 J1 isoform X1 [KO:K10578] [EC:2.3.2.23]
111855809  ube2j2; ubiquitin-conjugating enzyme E2 J2 [KO:K04554] [EC:2.3.2.23]
111854704  ube2g1; ubiquitin-conjugating enzyme E2 G1 [KO:K10575] [EC:2.3.2.23]
111855127  ubiquitin-conjugating enzyme E2 G1-like [KO:K10575] [EC:2.3.2.23]
111856820  ubiquitin-conjugating enzyme E2 G1-like isoform X1 [KO:K10575] [EC:2.3.2.23]
111858368  ube2g2; ubiquitin-conjugating enzyme E2 G2 [KO:K04555] [EC:2.3.2.23]
111836392  syvn1; E3 ubiquitin-protein ligase synoviolin [KO:K10601] [EC:2.3.2.27]
111842128  rnf185; E3 ubiquitin-protein ligase RNF185 [KO:K10666] [EC:2.3.2.27]
111844994  selenos; selenoprotein S [KO:K14025]
111838839  protein sel-1 homolog 1-like isoform X1 [KO:K14026]
111838664  sel1l; protein sel-1 homolog 1 isoform X1 [KO:K14026]
111851896  herpud1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein [KO:K14027]
111832691  amfr; E3 ubiquitin-protein ligase AMFR [KO:K10636] [EC:2.3.2.36]
111858177  E3 ubiquitin-protein ligase AMFR-like [KO:K10636] [EC:2.3.2.36]
111847726  stub1; E3 ubiquitin-protein ligase CHIP isoform X1 [KO:K09561] [EC:2.3.2.27]
111852997  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
111843768  ubiquitin-conjugating enzyme E2 D4-like isoform X1 [KO:K06689] [EC:2.3.2.23]
111853660  ube2d1; ubiquitin-conjugating enzyme E2 D1 [KO:K06689] [EC:2.3.2.23]
111833177  ubiquitin-conjugating enzyme E2 D2-like isoform X1 [KO:K06689] [EC:2.3.2.23]
111836741  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
111857534  ubiquitin-conjugating enzyme E2 D4 isoform X1 [KO:K06689] [EC:2.3.2.23]
111853949  ubiquitin-conjugating enzyme E2 D2-like isoform X1 [KO:K06689] [EC:2.3.2.23]
111848830  prkn; E3 ubiquitin-protein ligase parkin isoform X1 [KO:K04556] [EC:2.3.2.31]
111845210  rbx1; E3 ubiquitin-protein ligase RBX1 [KO:K03868] [EC:2.3.2.32]
111853244  RING-box protein 1 [KO:K03868] [EC:2.3.2.32]
111834008  cullin-1-like [KO:K03347]
111855000  cullin-1 [KO:K03347]
111847937  skp1; S-phase kinase-associated protein 1 [KO:K03094]
111839552  S-phase kinase-associated protein 1 [KO:K03094]
111840967  F-box only protein 2-like isoform X1 [KO:K10099]
111834354  F-box only protein 6-like isoform X1 [KO:K10100]
111834356  F-box only protein 44-like isoform X1 [KO:K10100]
Compound
C00076  Calcium cation
G00009   
G00010   
G00011   
G00012   
G10694   
Reference
  Authors
Naidoo N
  Title
ER and aging-Protein folding and the ER stress response.
  Journal
Ageing Res Rev 8:150-9 (2009)
DOI:10.1016/j.arr.2009.03.001
Reference
  Authors
Malhotra JD, Kaufman RJ
  Title
The endoplasmic reticulum and the unfolded protein response.
  Journal
Semin Cell Dev Biol 18:716-31 (2007)
DOI:10.1016/j.semcdb.2007.09.003
Reference
  Authors
Maattanen P, Gehring K, Bergeron JJ, Thomas DY
  Title
Protein quality control in the ER: the recognition of misfolded proteins.
  Journal
Semin Cell Dev Biol 21:500-11 (2010)
DOI:10.1016/j.semcdb.2010.03.006
Reference
  Authors
Stolz A, Wolf DH
  Title
Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell.
  Journal
Biochim Biophys Acta 1803:694-705 (2010)
DOI:10.1016/j.bbamcr.2010.02.005
Reference
  Authors
Dejgaard K, Theberge JF, Heath-Engel H, Chevet E, Tremblay ML, Thomas DY
  Title
Organization of the Sec61 translocon, studied by high resolution native electrophoresis.
  Journal
J Proteome Res 9:1763-71 (2010)
DOI:10.1021/pr900900x
Related
pathway
pki00510  N-Glycan biosynthesis
pki03050  Proteasome
pki03060  Protein export
pki04210  Apoptosis
KO pathway
ko04141   
LinkDB

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