KEGG   PATHWAY: sbia03083
Entry
sbia03083                   Pathway                                
Name
Polycomb repressive complex - Syngnathoides biaculeatus (alligator pipefish)
Class
Genetic Information Processing; Chromosome
Pathway map
sbia03083  Polycomb repressive complex
sbia03083

Organism
Syngnathoides biaculeatus (alligator pipefish) [GN:sbia]
Gene
133514174  ezh1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
133492409  ezh2; histone-lysine N-methyltransferase EZH2 [KO:K11430] [EC:2.1.1.356]
133506113  eed; polycomb protein eed [KO:K11462]
133514936  polycomb protein suz12-B-like [KO:K11463]
133506775  suz12b; polycomb protein suz12-B isoform X1 [KO:K11463]
133512956  rbbp4; histone-binding protein RBBP4 [KO:K10752]
133501454  phf1; PHD finger protein 1 isoform X1 [KO:K11467]
133511215  mtf2; metal-response element-binding transcription factor 2 isoform X1 [KO:K11485]
133500029  phf19; PHD finger protein 19 isoform X1 [KO:K11486]
133506027  lcor; ligand-dependent corepressor isoform X1 [KO:K26260]
133502557  zinc finger protein aebp2-like [KO:K17452]
133493251  aebp2; zinc finger protein AEBP2 isoform X1 [KO:K17452]
133500939  jarid2b; LOW QUALITY PROTEIN: protein Jumonji [KO:K11478]
133507052  bap1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 [KO:K08588] [EC:3.4.19.12]
133511811  asxl1; putative Polycomb group protein ASXL1 [KO:K11471]
133513652  asxl2; putative Polycomb group protein ASXL2 [KO:K11471]
133508485  ogt.1; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
133507249  hcfc1a; host cell factor 1a [KO:K14966]
133496327  yy1b; transcriptional repressor protein YY1b isoform X1 [KO:K09201]
133513285  yy1a; transcriptional repressor protein YY1a isoform X1 [KO:K09201]
133505927  mbd6; methyl-CpG-binding domain protein 5 isoform X1 [KO:K23219]
133514677  foxk2b; forkhead box protein K2 isoform X1 [KO:K09404]
133506498  foxk1; forkhead box protein K1 [KO:K09404]
133495403  foxk2a; forkhead box protein K2 [KO:K09404]
133510965  rnf2; E3 ubiquitin-protein ligase RING2 isoform X1 [KO:K10695] [EC:2.3.2.27]
133493030  bmi1a; LOW QUALITY PROTEIN: polycomb complex protein BMI-1-A [KO:K11459]
133496090  chromobox protein homolog 2-like isoform X1 [KO:K11451]
133514946  cbx2; chromobox protein homolog 2 [KO:K11451]
133506620  cbx4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
133515034  cbx7a; chromobox homolog 7a [KO:K11454]
133495528  cbx7b; chromobox protein homolog 7 isoform X1 [KO:K11454]
133514773  cbx8a; chromobox protein homolog 8a [KO:K11455]
133506657  cbx8b; chromobox protein homolog 8b [KO:K11455]
133500692  phc1; polyhomeotic-like protein 1 isoform X1 [KO:K11456]
133500947  polyhomeotic-like protein 1 isoform X1 [KO:K11456]
133507845  phc2b; polyhomeotic-like protein 2b [KO:K11457]
133492508  polyhomeotic-like protein 3 isoform X1 [KO:K11458]
133503232  sex comb on midleg-like protein 2 [KO:K11465]
133497888  scml2; polycomb protein SCMH1 isoform X1 [KO:K11465]
133500999  polycomb protein SCMH1 isoform X1 [KO:K11461]
133493173  sfmbt2; scm-like with four MBT domains protein 2 isoform X1 [KO:K26269]
133506913  sfmbt1; scm-like with four MBT domains protein 1 isoform X1 [KO:K26269]
133508991  aurora kinase B-like isoform X1 [KO:K11479] [EC:2.7.11.1]
133509120  aurora kinase B-like [KO:K11479] [EC:2.7.11.1]
133509129  aurora kinase B-like [KO:K11479] [EC:2.7.11.1]
133508367  aurora kinase B-like [KO:K11479] [EC:2.7.11.1]
133508368  aurora kinase B-like isoform X1 [KO:K11479] [EC:2.7.11.1]
133495973  ubiquitin-conjugating enzyme E2 D2-like isoform X1 [KO:K06689] [EC:2.3.2.23]
133508990  ube2d2; ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
133509403  ubiquitin-conjugating enzyme E2 D4-like [KO:K06689] [EC:2.3.2.23]
133499776  ube2d4; ubiquitin-conjugating enzyme E2 D4 isoform X1 [KO:K06689] [EC:2.3.2.23]
133513538  ubiquitin-conjugating enzyme E2 D3-like [KO:K06689] [EC:2.3.2.23]
133504535  usp16; ubiquitin carboxyl-terminal hydrolase 16 [KO:K11844] [EC:3.4.19.12]
133501135  usp45; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 45 [KO:K11844] [EC:3.4.19.12]
133507866  rybpb; RING1 and YY1-binding protein B [KO:K11469]
133502630  YY1-associated factor 2-like [KO:K11468]
133493342  yaf2; YY1-associated factor 2 isoform X1 [KO:K11468]
133509116  pcgf1; polycomb group RING finger protein 1 isoform X1 [KO:K11487]
133515246  lysine-specific demethylase 2B-like isoform X1 [KO:K10276] [EC:1.14.11.27]
133499766  kdm2ba; lysine (K)-specific demethylase 2Ba isoform X1 [KO:K10276] [EC:1.14.11.27]
133506764  kdm2aa; lysine (K)-specific demethylase 2Aa isoform X1 [KO:K10276] [EC:1.14.11.27]
133508266  kdm2ab; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
133512231  bcor; BCL-6 corepressor isoform X1 [KO:K23215]
133508560  bcorl1; LOW QUALITY PROTEIN: BCL-6 corepressor-like protein 1 [KO:K26199]
133492102  skp1; S-phase kinase-associated protein 1 [KO:K03094]
133514408  usp7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
133508379  polycomb group RING finger protein 3 [KO:K11488]
133510220  pcgf5b; polycomb group RING finger protein 5-B [KO:K11489]
133500019  csnk2b; casein kinase II subunit beta [KO:K03115]
133491497  auts2a; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
133495511  fbrs; autism susceptibility gene 2 protein isoform X1 [KO:K26253]
133499115  fbrsl1; autism susceptibility gene 2 protein isoform X1 [KO:K26254]
133514663  dcaf7; DDB1- and CUL4-associated factor 7 isoform X1 [KO:K11805]
133500479  tex10; testis-expressed protein 10 homolog [KO:K14827]
133514776  crebbpb; CREB binding protein b [KO:K04498] [EC:2.3.1.48]
133514854  ep300b; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
133505800  crebbpa; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
133495523  ep300a; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
133509636  pcgf6; polycomb group RING finger protein 6 [KO:K11470]
133496898  e2f6; transcription factor E2F6 [KO:K09390]
133512299  transcription factor Dp-1-like [KO:K04683]
133496409  max; protein max isoform X1 [KO:K04453]
133513603  protein max-like isoform X1 [KO:K04453]
133496480  magl; MAX gene-associated protein isoform X1 [KO:K23399]
133492752  lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
133501194  l3mbtl1b; lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
133495526  l3mbtl2; lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
133497770  cbx3a; chromobox protein homolog 3a [KO:K11586]
133500560  cbx3b; chromobox protein homolog 3b [KO:K11586]
133490717  wdr5; WD repeat-containing protein 5 [KO:K14963]
133500113  probable histone deacetylase 1-B isoform X1 [KO:K06067] [EC:3.5.1.98]
133513533  histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
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