KEGG   PATHWAY: stru04142
Entry
stru04142                   Pathway                                
Name
Lysosome - Salmo trutta (river trout)
Description
Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy.
Class
Cellular Processes; Transport and catabolism
Pathway map
stru04142  Lysosome
stru04142

Other DBs
GO: 0005764
Organism
Salmo trutta (river trout) [GN:stru]
Gene
115171120  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
115159435  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
115161297  atp6v0a1; V-type proton ATPase 116 kDa subunit a isoform X1 [KO:K02154]
115164441  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
115173365  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
115148718  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
115202166  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
115204198  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
115198047  V-type proton ATPase 116 kDa subunit a-like isoform X1 [KO:K02154]
115205323  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
115200200  V-type proton ATPase 116 kDa subunit a-like [KO:K02154]
115181475  V-type proton ATPase subunit d 1-like [KO:K02146]
115156669  V-type proton ATPase subunit d 1-like [KO:K02146]
115203536  V-type proton ATPase subunit d 1 [KO:K02146]
115157691  V-type proton ATPase subunit H-like isoform X1 [KO:K02144]
115170258  V-type proton ATPase subunit H isoform X1 [KO:K02144]
115167926  V-type proton ATPase subunit S1-like [KO:K03662]
115168752  V-type proton ATPase subunit S1-like [KO:K03662]
115165237  V-type proton ATPase subunit S1-like isoform X1 [KO:K03662]
115165583  V-type proton ATPase subunit S1-like [KO:K03662]
115192105  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
115170739  atp6v0c; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
115160022  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
115200968  V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
115157742  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
115169764  V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
115157006  V-type proton ATPase 21 kDa proteolipid subunit [KO:K03661]
115157007  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
115157008  V-type proton ATPase 21 kDa proteolipid subunit-like [KO:K03661]
115164953  dmxl1; dmX-like protein 1 isoform X1 [KO:K24155]
115166945  dmxl2; dmX-like protein 2 isoform X1 [KO:K24155]
115204762  dmX-like protein 2 [KO:K24155]
115160150  wdr7; WD repeat-containing protein 7 isoform X1 [KO:K24738]
115191280  nuclear receptor coactivator 7-like isoform X1 [KO:K25442]
115174670  ncoa7; nuclear receptor coactivator 7 isoform X1 [KO:K25442]
115162562  nuclear receptor coactivator 7-like [KO:K25442]
115172860  nuclear receptor coactivator 7-like isoform X1 [KO:K25442]
115150090  ctsa; lysosomal protective protein [KO:K13289] [EC:3.4.16.5]
115203138  lysosomal protective protein-like [KO:K13289] [EC:3.4.16.5]
115161960  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
115190111  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
115172214  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
115206584  dipeptidyl peptidase 1-like isoform X1 [KO:K01275] [EC:3.4.14.1]
115206587  dipeptidyl peptidase 1-like [KO:K01275] [EC:3.4.14.1]
115192717  cathepsin D-like isoform X1 [KO:K01379] [EC:3.4.23.5]
115170923  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
115166723  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
115196324  cathepsin D-like isoform X1 [KO:K01379] [EC:3.4.23.5]
115203603  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
115189933  cathepsin D-like [KO:K01382] [EC:3.4.23.34]
115189939  cathepsin D-like [KO:K01382] [EC:3.4.23.34]
115168960  cathepsin F-like isoform X1 [KO:K01373] [EC:3.4.22.41]
115205568  cathepsin F-like isoform X1 [KO:K01373] [EC:3.4.22.41]
115196734  pro-cathepsin H-like [KO:K01366] [EC:3.4.22.16]
115203334  pro-cathepsin H-like [KO:K01366] [EC:3.4.22.16]
115176788  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
115178886  cathepsin K-like [KO:K01371] [EC:3.4.22.38]
115191546  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115159190  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115159192  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115159193  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115159194  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115159195  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115159196  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115162579  cathepsin L1-like isoform X1 [KO:K01365] [EC:3.4.22.15]
115172882  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115149355  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
115208514  cathepsin L1-like isoform X1 [KO:K01365] [EC:3.4.22.15]
115170744  ctso; cathepsin O [KO:K01374] [EC:3.4.22.42]
115176789  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
115178898  cathepsin S-like [KO:K01368] [EC:3.4.22.27]
115157612  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
115150442  cathepsin Z-like isoform X1 [KO:K08568] [EC:3.4.18.1]
115207978  cathepsin Z-like [KO:K08568] [EC:3.4.18.1]
115161884  lgmn; legumain [KO:K01369] [EC:3.4.22.34]
115172170  legumain-like [KO:K01369] [EC:3.4.22.34]
115162649  tpp1; tripeptidyl-peptidase 1 [KO:K01279] [EC:3.4.14.9]
115169827  gla; alpha-galactosidase A isoform X1 [KO:K01189] [EC:3.2.1.22]
115191921  glb1; beta-galactosidase [KO:K12309] [EC:3.2.1.23]
115183747  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
115171667  lysosomal alpha-glucosidase-like isoform X1 [KO:K12316] [EC:3.2.1.20]
115147680  lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
115197541  LOW QUALITY PROTEIN: lysosomal alpha-glucosidase-like [KO:K12316] [EC:3.2.1.20]
115176398  lysosomal acid glucosylceramidase-like [KO:K01201] [EC:3.2.1.45]
115177217  lysosomal acid glucosylceramidase-like [KO:K01201] [EC:3.2.1.45]
115200326  idua; alpha-L-iduronidase isoform X1 [KO:K01217] [EC:3.2.1.76]
115174693  alpha-N-acetylgalactosaminidase-like [KO:K01204] [EC:3.2.1.49]
115175520  alpha-N-acetylgalactosaminidase-like isoform X1 [KO:K01204] [EC:3.2.1.49]
115161322  naglu; alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
115172317  galc; galactocerebrosidase isoform X1 [KO:K01202] [EC:3.2.1.46]
115153890  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
115148427  beta-glucuronidase-like [KO:K01195] [EC:3.2.1.31]
115189047  fuca1; tissue alpha-L-fucosidase [KO:K01206] [EC:3.2.1.51]
115187227  tissue alpha-L-fucosidase-like [KO:K01206] [EC:3.2.1.51]
115172225  fuca2; plasma alpha-L-fucosidase [KO:K01206] [EC:3.2.1.51]
115159850  LOW QUALITY PROTEIN: beta-hexosaminidase subunit beta-like [KO:K12373] [EC:3.2.1.52]
115203828  beta-hexosaminidase subunit beta-like isoform X1 [KO:K12373] [EC:3.2.1.52]
115197752  beta-hexosaminidase subunit alpha-like isoform X1 [KO:K12373] [EC:3.2.1.52]
115173039  manba; beta-mannosidase [KO:K01192] [EC:3.2.1.25]
115191200  lysosomal alpha-mannosidase-like [KO:K12311] [EC:3.2.1.24]
115147423  lysosomal alpha-mannosidase-like [KO:K12311] [EC:3.2.1.24]
115176015  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
115173402  sialidase-1-like [KO:K01186] [EC:3.2.1.18]
115180176  hyaluronidase PH-20-like [KO:K01197] [EC:3.2.1.35]
115192734  hyaluronidase-5-like [KO:K01197] [EC:3.2.1.35]
115192733  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
115168307  hyaluronidase-3-like [KO:K01197] [EC:3.2.1.35]
115166431  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
115150943  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
115150228  hyaluronidase-2-like isoform X1 [KO:K01197] [EC:3.2.1.35]
115207485  hyaluronidase-1-like [KO:K01197] [EC:3.2.1.35]
115207486  hyaluronidase-2-like isoform X1 [KO:K01197] [EC:3.2.1.35]
115208234  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
115197028  hyaluronidase-like [KO:K01197] [EC:3.2.1.35]
115197029  hyaluronidase PH-20-like [KO:K01197] [EC:3.2.1.35]
115197788  hyaluronidase-4-like [KO:K01197] [EC:3.2.1.35]
115197260  arsa; arylsulfatase A [KO:K01134] [EC:3.1.6.8]
115203930  arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
115201402  arsg; arylsulfatase G [KO:K12381] [EC:3.1.6.-]
115167380  galns; N-acetylgalactosamine-6-sulfatase isoform X1 [KO:K01132] [EC:3.1.6.4]
115189798  gns; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
115159890  N-acetylglucosamine-6-sulfatase-like [KO:K01137] [EC:3.1.6.14]
115205471  iduronate 2-sulfatase-like [KO:K01136] [EC:3.1.6.13]
115181670  N-sulphoglucosamine sulphohydrolase-like isoform X1 [KO:K01565] [EC:3.10.1.1]
115147563  N-sulphoglucosamine sulphohydrolase-like [KO:K01565] [EC:3.10.1.1]
115157138  lysosomal acid lipase/cholesteryl ester hydrolase-like isoform X1 [KO:K01052] [EC:3.1.1.13]
115201165  lysosomal acid lipase/cholesteryl ester hydrolase-like [KO:K01052] [EC:3.1.1.13]
115151852  group XV phospholipase A2-like [KO:K06129] [EC:3.1.1.5]
115196915  group XV phospholipase A2-like [KO:K06129] [EC:3.1.1.5]
115176907  deoxyribonuclease-2-alpha-like isoform X1 [KO:K01158] [EC:3.1.22.1]
115178324  deoxyribonuclease-2-alpha-like [KO:K01158] [EC:3.1.22.1]
115167532  acp2; lysosomal acid phosphatase [KO:K14410] [EC:3.1.3.2]
115202871  lysosomal acid phosphatase-like [KO:K14410] [EC:3.1.3.2]
115153110  tartrate-resistant acid phosphatase type 5-like isoform X1 [KO:K14379] [EC:3.1.3.2]
115178653  tartrate-resistant acid phosphatase type 5-like isoform X1 [KO:K14379] [EC:3.1.3.2]
115147335  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
115195348  tartrate-resistant acid phosphatase type 5-like [KO:K14379] [EC:3.1.3.2]
115204681  smpd1; sphingomyelin phosphodiesterase [KO:K12350] [EC:3.1.4.12]
115191910  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
115202129  acid ceramidase-like [KO:K12348] [EC:3.5.1.23]
115153141  uncharacterized protein LOC115153141 [KO:K01444] [EC:3.5.1.26]
115170787  aga; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase [KO:K01444] [EC:3.5.1.26]
115155734  prosaposin-like isoform X1 [KO:K12382]
115164457  prosaposin-like [KO:K12382]
115201750  prosaposin-like isoform X1 [KO:K12382]
115160216  prosaposin-like [KO:K12382]
115199593  prosaposin-like [KO:K12382]
115204190  prosaposin-like isoform X1 [KO:K12382]
115167280  ganglioside GM2 activator-like [KO:K12383]
115205716  ganglioside GM2 activator-like [KO:K12383]
115175965  palmitoyl-protein thioesterase 1-like isoform X1 [KO:K01074] [EC:3.1.2.22]
115176028  lysosomal thioesterase PPT2-A-like [KO:K01074] [EC:3.1.2.22]
115177033  lysosomal thioesterase PPT2-A-like isoform X1 [KO:K01074] [EC:3.1.2.22]
115177630  lysosomal thioesterase PPT2-A-like isoform X1 [KO:K01074] [EC:3.1.2.22]
115173318  lysosomal thioesterase PPT2-A-like [KO:K01074] [EC:3.1.2.22]
115173451  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
115155891  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
115179524  lamp1; lysosome-associated membrane glycoprotein 1 [KO:K06528]
115161282  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
115205067  lysosome-associated membrane glycoprotein 2-like isoform X1 [KO:K06528]
115170070  lysosome-associated membrane glycoprotein 2-like isoform X1 [KO:K06528]
115192469  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
115158427  lysosome-associated membrane glycoprotein 3-like [KO:K06562]
115198080  macrosialin-like [KO:K06501]
115168015  CD63 antigen-like [KO:K06497]
115165671  CD63 antigen-like [KO:K06497]
115164770  lysosome membrane protein 2-like [KO:K12384]
115160242  lysosome membrane protein 2-like [KO:K12384]
115149499  lysosome membrane protein 2-like [KO:K12384]
115149500  scarb2; lysosome membrane protein 2 [KO:K12384]
115199881  lysosome membrane protein 2-like [KO:K12384]
115169556  NPC intracellular cholesterol transporter 1-like [KO:K12385]
115157223  NPC intracellular cholesterol transporter 1-like [KO:K12385]
115172604  npc2; NPC intracellular cholesterol transporter 2 [KO:K13443]
115158176  cystinosin-like isoform X1 [KO:K12386]
115151763  cystinosin-like isoform X1 [KO:K12386]
115193799  slc17a5; sialin [KO:K12301]
115175963  sialin-like [KO:K12301]
115173449  sialin-like isoform X1 [KO:K12301]
115167899  natural resistance-associated macrophage protein 2-like isoform X1 [KO:K21398]
115150446  natural resistance-associated macrophage protein 2-like isoform X1 [KO:K21398]
115207976  natural resistance-associated macrophage protein 2-like isoform X1 [KO:K21398]
115181443  lysosomal-associated transmembrane protein 4B-like isoform X1 [KO:K12387]
115175037  lysosomal-associated transmembrane protein 4A-like [KO:K12387]
115176774  lysosomal-associated transmembrane protein 4B-like [KO:K12387]
115195739  lysosomal-associated transmembrane protein 4A-like [KO:K12387]
115164170  ATP-binding cassette sub-family A member 2-like isoform X1 [KO:K05642]
115200469  ATP-binding cassette sub-family A member 2-like isoform X1 [KO:K05642]
115164275  ATP-binding cassette sub-family B member 9-like isoform X1 [KO:K05656]
115200379  ATP-binding cassette sub-family B member 9-like [KO:K05656]
115174436  sialomucin core protein 24-like [KO:K06546]
115176985  cd164; sialomucin core protein 24 isoform X1 [KO:K06546]
115164549  ectonucleoside triphosphate diphosphohydrolase 4-like isoform X1 [KO:K12305] [EC:3.6.1.6]
115180367  sortilin-like [KO:K12388]
115168686  sortilin-like [KO:K12388]
115165329  sortilin-like isoform X1 [KO:K12388]
115150672  sortilin-like [KO:K12388]
115199093  sortilin-like [KO:K12388]
115170777  cln3; battenin isoform X1 [KO:K12389]
115156249  cln5; ceroid-lipofuscinosis neuronal protein 5 [KO:K12390]
115157711  major facilitator superfamily domain-containing protein 8-like [KO:K12307]
115152512  uncharacterized protein LOC115152512 [KO:K12307]
115198063  mfsd8; major facilitator superfamily domain-containing protein 8 isoform X1 [KO:K12307]
115194001  heparan-alpha-glucosaminide N-acetyltransferase-like isoform X1 [KO:K10532] [EC:2.3.1.78]
115187357  heparan-alpha-glucosaminide N-acetyltransferase-like isoform X1 [KO:K10532] [EC:2.3.1.78]
115187381  hgsnat; heparan-alpha-glucosaminide N-acetyltransferase [KO:K10532] [EC:2.3.1.78]
115207912  formylglycine-generating enzyme-like isoform X1 [KO:K13444] [EC:1.8.3.7]
115180191  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
115198933  N-acetylglucosamine-1-phosphotransferase subunits alpha/beta-like [KO:K08239] [EC:2.7.8.17]
115159578  gnptg; N-acetylglucosamine-1-phosphotransferase subunit gamma [KO:K10087]
115179583  N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like isoform X1 [KO:K01125] [EC:3.1.4.45]
115192936  cation-independent mannose-6-phosphate receptor-like [KO:K06564]
115174818  cation-independent mannose-6-phosphate receptor-like isoform X1 [KO:K06564]
115188316  cation-dependent mannose-6-phosphate receptor-like [KO:K10089]
115177421  cation-dependent mannose-6-phosphate receptor-like [KO:K10089]
115191849  clathrin light chain A-like isoform X1 [KO:K04644]
115202182  clathrin light chain A-like isoform X1 [KO:K04644]
115166381  clathrin light chain B-like isoform X1 [KO:K04645]
115205768  clathrin light chain B-like isoform X1 [KO:K04645]
115154329  clathrin heavy chain 1-like isoform X1 [KO:K04646]
115163518  clathrin heavy chain 1-like isoform X1 [KO:K04646]
115164348  clathrin heavy chain 1-like isoform X1 [KO:K04646]
115148866  clathrin heavy chain 1 isoform X1 [KO:K04646]
115206427  clathrin heavy chain 1-like isoform X1 [KO:K04646]
115200281  clathrin heavy chain 1-like isoform X1 [KO:K04646]
115169482  AP-1 complex subunit gamma-1-like [KO:K12391]
115167252  AP-1 complex subunit gamma-1-like isoform X1 [KO:K12391]
115157324  AP-1 complex subunit gamma-1-like [KO:K12391]
115203087  AP-1 complex subunit gamma-1 isoform X1 [KO:K12391]
115164445  AP-1 complex subunit beta-1 isoform X1 [KO:K12392]
115200193  AP-1 complex subunit beta-1-like [KO:K12392]
115192213  AP-1 complex subunit mu-1-like [KO:K12393]
115158155  AP-1 complex subunit mu-1 [KO:K12393]
115158744  AP-1 complex subunit mu-2-like [KO:K12393]
115178269  AP-1 complex subunit mu-2-like [KO:K12393]
115147370  AP-1 complex subunit mu-2 [KO:K12393]
115151747  ap1m1; AP-1 complex subunit mu-1 isoform X1 [KO:K12393]
115183231  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12394]
115188779  AP-1 complex subunit sigma-2 isoform X1 [KO:K12394]
115194612  AP-1 complex subunit sigma-1A-like isoform X1 [KO:K12394]
115198565  AP-1 complex subunit sigma-1A [KO:K12394]
115157475  AP-1 complex subunit sigma-3-like isoform X1 [KO:K12395]
115169332  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12395]
115163629  AP-1 complex subunit sigma-2-like isoform X1 [KO:K12395]
115206523  AP-1 complex subunit sigma-3-like [KO:K12395]
115192590  AP-3 complex subunit delta-1-like isoform X1 [KO:K12396]
115158288  AP-3 complex subunit delta-1-like isoform X1 [KO:K12396]
115159730  AP-3 complex subunit beta-1-like isoform X1 [KO:K12397]
115197154  ap3b2; AP-3 complex subunit beta-2 isoform X1 [KO:K12397]
115203934  ap3b1; AP-3 complex subunit beta-1 [KO:K12397]
115153613  AP-3 complex subunit mu-1-like isoform X1 [KO:K12398]
115164299  AP-3 complex subunit mu-2 [KO:K12398]
115200350  AP-3 complex subunit mu-2-like isoform X1 [KO:K12398]
115164964  ap3s1; AP-3 complex subunit sigma-1 [KO:K12399]
115182689  AP-3 complex subunit sigma-2 [KO:K12399]
115203686  AP-3 complex subunit sigma-2-like [KO:K12399]
115199721  AP-3 complex subunit sigma-1 isoform X1 [KO:K12399]
115192894  ap4e1; AP-4 complex subunit epsilon-1 [KO:K12400]
115166442  ap4b1; AP-4 complex subunit beta-1 [KO:K12401]
115154402  ap4m1; AP-4 complex subunit mu-1 [KO:K12402]
115172371  ap4s1; AP-4 complex subunit sigma-1 [KO:K12403]
115171308  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
115177595  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
115177625  ADP-ribosylation factor-binding protein GGA3-like isoform X1 [KO:K12404]
115171714  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
115177919  ADP-ribosylation factor-binding protein GGA2-like [KO:K12404]
115178441  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
115147193  ADP-ribosylation factor-binding protein GGA3-like isoform X1 [KO:K12404]
115147324  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
115205911  ADP-ribosylation factor-binding protein GGA3-like [KO:K12404]
115200182  ADP-ribosylation factor-binding protein GGA1-like [KO:K12404]
115170544  mucolipin-1-like [KO:K04992]
115177804  mucolipin-1-like [KO:K04992]
115201301  mucolipin-1-like [KO:K04992]
115208613  mucolipin-1-like isoform X1 [KO:K04992]
115184982  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
115183503  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
115171205  uncharacterized protein LOC115171205 isoform X1 [KO:K19363]
115177815  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
115178800  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
115147602  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog isoform X1 [KO:K19363]
115147604  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
115198644  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
115198849  uncharacterized protein LOC115198849 isoform X1 [KO:K19363]
115206204  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
115183495  lipopolysaccharide-induced tumor necrosis factor-alpha factor-like [KO:K19363]
115189869  lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog [KO:K19363]
115200813  cell death-inducing p53-target protein 1 homolog [KO:K19363]
Compound
C00002  ATP
C00008  ADP
C00159  D-Mannose
C00275  D-Mannose 6-phosphate
Reference
PMID:12628346
  Authors
Eskelinen EL, Tanaka Y, Saftig P
  Title
At the acidic edge: emerging functions for lysosomal membrane proteins.
  Journal
Trends Cell Biol 13:137-45 (2003)
DOI:10.1016/S0962-8924(03)00005-9
Reference
PMID:1883197
  Authors
Neufeld EF
  Title
Lysosomal storage diseases.
  Journal
Annu Rev Biochem 60:257-80 (1991)
DOI:10.1146/annurev.bi.60.070191.001353
Reference
PMID:2943218
  Authors
von Figura K, Hasilik A
  Title
Lysosomal enzymes and their receptors.
  Journal
Annu Rev Biochem 55:167-93 (1986)
DOI:10.1146/annurev.bi.55.070186.001123
Reference
PMID:15987739
  Authors
Janvier K, Bonifacino JS
  Title
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins.
  Journal
Mol Biol Cell 16:4231-42 (2005)
DOI:10.1091/mbc.E05-03-0213
Reference
PMID:18635948
  Authors
Vergarajauregui S, Puertollano R
  Title
Mucolipidosis type IV: the importance of functional lysosomes for efficient autophagy.
  Journal
Autophagy 4:832-4 (2008)
DOI:10.4161/auto.6567
Reference
PMID:34249946
  Authors
Jaskolka MC, Winkley SR, Kane PM
  Title
RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification.
  Journal
Front Cell Dev Biol 9:698190 (2021)
DOI:10.3389/fcell.2021.698190
Reference
PMID:34646033
  Authors
Majdoul S, Compton AA
  Title
Lessons in self-defence: inhibition of virus entry by intrinsic immunity.
  Journal
Nat Rev Immunol 10.1038/s41577-021-00626-8 (2021)
DOI:10.1038/s41577-021-00626-8
Related
pathway
stru00511  Other glycan degradation
stru00531  Glycosaminoglycan degradation
stru04130  SNARE interactions in vesicular transport
stru04140  Autophagy - animal
stru04144  Endocytosis
KO pathway
ko04142   
LinkDB

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