KEGG   PATHWAY: sund04070
Entry
sund04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Sceloporus undulatus (fence lizard)
Class
Environmental Information Processing; Signal transduction
Pathway map
sund04070  Phosphatidylinositol signaling system
sund04070

Organism
Sceloporus undulatus (fence lizard) [GN:sund]
Gene
121916418  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
121915576  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
121926124  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha isoform X1 [KO:K13711] [EC:2.7.1.67]
121931525  PI4K2B; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
121934224  SACM1L; phosphatidylinositol-3-phosphatase SAC1 isoform X1 [KO:K21797] [EC:3.1.3.-]
121926075  INPP5F; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
121916297  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
121920195  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
121936597  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
121936340  LOW QUALITY PROTEIN: inositol polyphosphate 5-phosphatase OCRL-like [KO:K01099] [EC:3.1.3.36]
121916105  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
121936915  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
121924860  SYNJ1; LOW QUALITY PROTEIN: synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
121937307  SYNJ2; LOW QUALITY PROTEIN: synaptojanin-2 [KO:K20279] [EC:3.1.3.36]
121932579  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like isoform X1 [KO:K00922] [EC:2.7.1.153]
121925257  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
121925596  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
121937300  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
121928626  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
121923252  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
121925166  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
121927086  INPP5D; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
121925688  INPPL1; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
121925694  INPP4A; LOW QUALITY PROTEIN: inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
121932059  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
121930840  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
121936795  MTM1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
121926177  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
121937007  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
121916919  MTMR4; myotubularin-related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
121917706  myotubularin-related protein 3-like isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
121936564  myotubularin-related protein 8-like isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121926331  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121932126  MTMR7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
121922287  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
121933198  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
121922724  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
121934651  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
121930003  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
121934894  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
121922946  PIK3C3; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
121927575  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha-like [KO:K00923] [EC:2.7.1.154]
121929224  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
121933158  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
121918973  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
121918974  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
121915711  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
121923319  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
121934158  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [KO:K05857] [EC:3.1.4.11]
121934557  PLCD3; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
121925090  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
121929364  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
121929490  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like isoform X1 [KO:K01116] [EC:3.1.4.11]
121914835  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
121931569  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
121931749  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
121925588  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
121919014  ITPKB; LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
121924219  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
121916044  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
121925149  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
121919437  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
121921490  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
121929566  IP6K3; inositol hexakisphosphate kinase 3 isoform X1 [KO:K07756] [EC:2.7.4.21]
121921580  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
121922211  IP6K1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
121932642  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
121921012  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
121924194  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
121929512  IMPA2; inositol monophosphatase 2 isoform X1 [KO:K01092] [EC:3.1.3.25]
121929587  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
121935018  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase isoform X1 [KO:K15759] [EC:3.1.3.7]
121917255  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
121923170  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
121923598  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
121935324  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
121925631  DGKG; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
121925702  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
121925855  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
121921416  DGKA; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
121931405  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
121937210  DGKK; diacylglycerol kinase kappa isoform X1 [KO:K00901] [EC:2.7.1.107]
121934758  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
121931802  CDS1; phosphatidate cytidylyltransferase 1 isoform X1 [KO:K00981] [EC:2.7.7.41]
121932768  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
121921093  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
121932190  ITPR2; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
121928090  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
121924105  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
121937565  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
121932615  PRKCG; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
121933110  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
121930342  CALM1; calmodulin-1 [KO:K02183]
121915316  CALM3; calmodulin-3 [KO:K02183]
121921338  CALM2; calmodulin-2 [KO:K02183]
121915509  calmodulin-1 [KO:K02183]
121936891  CALML6; calmodulin-like protein 6 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
sund04020  Calcium signaling pathway
sund04144  Endocytosis
sund04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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