KEGG   PATHWAY: plop04070
Entry
plop04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Perognathus longimembris pacificus (Pacific pocket mouse)
Class
Environmental Information Processing; Signal transduction
Pathway map
plop04070  Phosphatidylinositol signaling system
plop04070

Organism
Perognathus longimembris pacificus (Pacific pocket mouse) [GN:plop]
Gene
125338673  Prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
125338749  Calml4; calmodulin-like protein 4 isoform X1 [KO:K02183]
125339602  Mtmr7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125339868  Ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
125340329  Itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
125340531  Prkcb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
125340765  Plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
125340797  Cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
125340951  Pip5k1b; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
125341163  Ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
125341302  [KO:K02183]
125341579  Inpp4b; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
125342393  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
125342474  Plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
125342573  Ip6k1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
125342574  Ip6k2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
125342612  Sacm1l; phosphatidylinositol-3-phosphatase SAC1 isoform X1 [KO:K21797] [EC:3.1.3.-]
125342732  Plcz1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
125342733  Pik3c2g; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
125342841  Itpr2; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
125343116  Dgkk; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
125343245  Mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
125343356  Mtmr1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125343612  Ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
125343731  [KO:K02183]
125343893  Mtmr8; myotubularin-related protein 8 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125343908  Pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
125344942  [KO:K02183]
125345118  [KO:K05857] [EC:3.1.4.11]
125345807  Dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
125345932  Inpp5a; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
125345990  Inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
125346194  Pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
125346260  Plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
125346333  Ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
125347186  Dgki; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
125348240  Dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
125348415  Mtmr6; myotubularin-related protein 6 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125348631  Pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
125348916  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
125349269  Mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
125349339  Pi4ka; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
125349699  Mtmr2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125349719  Ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
125350165  Dgkd; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
125350166  Inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
125350302  Plcd4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
125350347  Pikfyve; LOW QUALITY PROTEIN: 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
125350463  Inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
125351506  Synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
125351905  Dgkg; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
125351954  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
125352689  Ip6k3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
125352691  Itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
125353096  [KO:K02183]
125353265  Plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
125353267  Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
125353287  Cds2; LOW QUALITY PROTEIN: phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
125353335  Inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
125353663  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
125354420  Calml6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
125354550  Pik3cd; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
125354943  Inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
125355095  Pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
125356035  Inpp4a; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
125356469  Calm2; calmodulin-2 [KO:K02183]
125357444  Synj2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
125357867  Plcg2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
125358523  Pip4p1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
125358713  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125358763  Itpr1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
125358784  Mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
125359078  Pip5k1a; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
125359415  Pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
125359684  Itpkb; LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
125360130  Pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
125360504  Bpnt2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
125360720  Impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
125360907  Pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
125361189  Inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
125361212  Dgkz; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
125361661  Pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
125362188  Pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
125362680  Plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
125363070  Calm1; calmodulin-1 [KO:K02183]
125363153  Dgka; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
125363658  Itpk1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
125363831  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
125363840  Impa2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
125364474  Dgkq; diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
125364599  Pi4k2b; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
125364706  Cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
125364893  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125365264  Pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
125365798  Dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
125366443  Prkca; LOW QUALITY PROTEIN: protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
125366455  Mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
125366489  Plcd3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [KO:K05857] [EC:3.1.4.11]
125367238  [KO:K02183]
125367315  Pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
125367817  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
125368270  Itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
125368360  Calm3; calmodulin-3 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
plop04020  Calcium signaling pathway
plop04144  Endocytosis
plop04151  PI3K-Akt signaling pathway
plop04510  Focal adhesion
KO pathway
ko04070   

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