KEGG    Network variation - Pancreatic cancer
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ENTRYnt06262
NamePancreatic cancer
CategoryDisease view; Cancer
Pathwayhsa05212 Pancreatic cancer
DiseaseH00019 Pancreatic cancer
Display drug-target relation   disease type
ERK signaling
N00216    HGFMETGRB2SOSRASRAFMEKERK
N00012            (KRAS*,NRAS*)RAFMEKERKCCND1
 
Other RAS signaling
N00103    EGFEGFRGRB2SOSRASRALGDSRAL
N00104            KRAS*RALGDSRAL
 
PI3K signaling
N00284          AREGEGFRPI3KPIP3AKTMTORS6K
N00034          EGF(ERBB2*+EGFR)PI3KPIP3AKTMTORS6K
N00218    FLT3LGFLT3GRB2SOSRASPI3KPIP3AKTMTOR
N00032            (KRAS*,NRAS*)PI3KPIP3AKTBAD
 
JAK-STAT signaling
N00094    EGFEGFRJAK1STAT1/3/5
N00095    EGF(ERBB2*+EGFR)JAK1STAT1/3VEGFA
 
Cell cycle
N00069    CDKN2A(CCND+CDK4/6)RB1E2F
N00070    CDKN2A*(CCND+CDK4/6)RB1E2F
N00071    CDKN2A*(CCND+CDK4/6)RB1E2F
 
Transcription
N00115    TP53*(CDKN1A,GADD45,BAX..