KEGG   PATHWAY: mcf05200
Entry
mcf05200                    Pathway                                
Name
Pathways in cancer - Macaca fascicularis (crab-eating macaque)
Class
Human Diseases; Cancer: overview
Pathway map
mcf05200  Pathways in cancer
mcf05200

Organism
Macaca fascicularis (crab-eating macaque) [GN:mcf]
Gene
102138576  DCC; netrin receptor DCC isoform X4 [KO:K06765]
102144182  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
102126830  CASP9; LOW QUALITY PROTEIN: caspase-9 [KO:K04399] [EC:3.4.22.62]
102126071  APPL1; DCC-interacting protein 13-alpha isoform X1 [KO:K08733]
102143513  CDH1; cadherin-1 [KO:K05689]
102146984  CTNNB1; catenin beta-1 isoform X1 [KO:K02105]
102137432  CTNNA3; catenin alpha-3 [KO:K05691]
102133059  CTNNA1; catenin alpha-1 isoform X1 [KO:K05691]
102140007  CTNNA2; catenin alpha-2 isoform X2 [KO:K05691]
102142970  AXIN1; axin-1 isoform X1 [KO:K02157]
102129656  AXIN2; axin-2 isoform X1 [KO:K04385]
102126553  APC; adenomatous polyposis coli protein isoform X2 [KO:K02085]
102123489  APC2; adenomatous polyposis coli protein 2 isoform X3 [KO:K02085]
102133756  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
102142248  TCF7; LOW QUALITY PROTEIN: transcription factor 7 [KO:K02620]
102125513  TCF7L1; transcription factor 7-like 1 isoform X1 [KO:K04490]
102116470  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
101925349  LEF1; lymphoid enhancer-binding factor 1 isoform X2 [KO:K04492]
102120307  BIRC5; baculoviral IAP repeat-containing protein 5 [KO:K08731]
102133017  baculoviral IAP repeat-containing protein 5-like [KO:K08731]
102127966  MYC; myc proto-oncogene protein [KO:K04377]
102135329  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
102120871  WNT1; proto-oncogene Wnt-1 [KO:K03209]
102130917  WNT2B; protein Wnt-2b [KO:K00182]
102129174  WNT2; protein Wnt-2 [KO:K00182]
102131688  WNT3A; protein Wnt-3a isoform X1 [KO:K00312]
102129654  WNT3; proto-oncogene Wnt-3 isoform X1 [KO:K00312]
102143058  WNT4; protein Wnt-4 isoform X1 [KO:K00408]
102146380  WNT5A; protein Wnt-5a isoform X1 [KO:K00444]
102129552  WNT5B; protein Wnt-5b isoform X1 [KO:K00444]
102132660  WNT6; protein Wnt-6 [KO:K00445]
102137321  WNT7A; protein Wnt-7a isoform X1 [KO:K00572]
102135636  WNT7B; protein Wnt-7b isoform X2 [KO:K00572]
102121324  WNT8B; protein Wnt-8b [KO:K00714]
102120527  WNT8A; protein Wnt-8a [KO:K00714]
102130297  WNT9B; protein Wnt-9b isoform X1 [KO:K01064]
101867270  WNT9A; protein Wnt-9a [KO:K01064]
102121241  WNT10B; protein Wnt-10b isoform X1 [KO:K01357]
102133672  WNT10A; protein Wnt-10a [KO:K01357]
102130649  WNT11; protein Wnt-11 isoform X2 [KO:K01384]
102142460  WNT16; protein Wnt-16 isoform X1 [KO:K01558]
102123369  FZD1; frizzled-1 [KO:K02432]
102128172  FZD7; frizzled-7 [KO:K02432]
102121830  FZD2; frizzled-2 [KO:K02235]
102115052  FZD3; frizzled-3 [KO:K02329]
102134081  FZD4; frizzled-4 isoform X2 [KO:K02354]
102129777  FZD8; frizzled-8 [KO:K02375]
102143139  FZD5; frizzled-5 [KO:K02375]
102131578  FZD6; frizzled-6 isoform X1 [KO:K02376]
102142058  FZD9; frizzled-9 [KO:K02842]
102127626  FZD10; frizzled-10 [KO:K02842]
102144265  LRP6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
102145061  LRP5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068]
102130032  DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353]
102138928  DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353]
102143975  DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X2 [KO:K02353]
102117805  FRAT1; proto-oncogene FRAT1 [KO:K03069]
102118171  FRAT2; GSK-3-binding protein FRAT2 [KO:K03096]
102131020  F2; prothrombin [KO:K01313] [EC:3.4.21.5]
101926221  AGT; angiotensinogen isoform X1 [KO:K09821]
102137130  F2R; proteinase-activated receptor 1 [KO:K03914]
102117109  F2RL3; proteinase-activated receptor 4 isoform X2 [KO:K04236]
102125640  LOW QUALITY PROTEIN: lysophosphatidic acid receptor 1 [KO:K04289]
101864894  LPAR1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
102142017  lysophosphatidic acid receptor 1-like [KO:K04289]
102120852  LPAR2; lysophosphatidic acid receptor 2 [KO:K04291]
102142911  LPAR3; lysophosphatidic acid receptor 3 [KO:K04294]
101864899  LPAR4; lysophosphatidic acid receptor 4 [KO:K04275]
102146767  LPAR5; lysophosphatidic acid receptor 5 [KO:K08390]
102145478  LPAR6; lysophosphatidic acid receptor 6 [KO:K04273]
102130940  AGTR1; type-1 angiotensin II receptor isoform X1 [KO:K04166]
101867258  GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
102127819  GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639]
102118758  ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
102122452  ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1 [KO:K12331]
102143411  ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X9 [KO:K12330]
101865781  PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1 [KO:K19464]
101865630  RHOA; transforming protein RhoA [KO:K04513]
102140851  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
102133054  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
102124268  CXCL12; stromal cell-derived factor 1 isoform X5 [KO:K10031]
102142487  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
102119905  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 isoform X1 [KO:K04630]
102140224  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630]
101926144  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630]
102146759  PTGER1; prostaglandin E2 receptor EP1 subtype isoform X1 [KO:K04258]
102121812  PTGER2; prostaglandin E2 receptor EP2 subtype isoform X1 [KO:K04259]
102143455  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
101865027  PTGER4; prostaglandin E2 receptor EP4 subtype isoform X1 [KO:K04261]
102145630  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoform X10 [KO:K04632]
107126444  neuroendocrine secretory protein 55 [KO:K04632]
102147015  ADCY1; adenylate cyclase type 1 isoform X1 [KO:K08041] [EC:4.6.1.1]
102130114  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
101925741  ADCY3; adenylate cyclase type 3 isoform X2 [KO:K08043] [EC:4.6.1.1]
102123837  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
102135142  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
102116122  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
102125718  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
102144854  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
102135923  ADCY9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
102117414  PRKACG; cAMP-dependent protein kinase catalytic subunit gamma [KO:K04345] [EC:2.7.11.11]
102142443  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
101926461  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X4 [KO:K04345] [EC:2.7.11.11]
102120049  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
101867297  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
102125334  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
102125173  GNB4; guanine nucleotide-binding protein subunit beta-4 isoform X1 [KO:K04538]
101866657  GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X2 [KO:K04539]
101925341  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
101925867  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
102146209  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
102141053  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
102145967  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
123568653  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
123572350  LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
107128232  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1 [KO:K04544]
102125944  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like isoform X1 [KO:K04545]
107127614  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
102133905  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
102126944  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
123570590  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
102134312  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
102142284  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
102127262  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
102125366  COL4A6; collagen alpha-6(IV) chain isoform X2 [KO:K06237]
102118598  COL4A4; collagen alpha-4(IV) chain isoform X1 [KO:K06237]
102122146  COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
102131342  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
102122606  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
102145776  LAMA2; laminin subunit alpha-2 isoform X6 [KO:K05637]
102146003  LAMA1; laminin subunit alpha-1 isoform X2 [KO:K05637]
102128796  LAMA5; laminin subunit alpha-5 isoform X1 [KO:K06240]
102120952  LAMA3; laminin subunit alpha-3 isoform X2 [KO:K06240]
102132640  LAMA4; laminin subunit alpha-4 isoform X1 [KO:K06241]
102126233  LAMB1; laminin subunit beta-1 [KO:K05636]
102135628  LAMB2; laminin subunit beta-2 isoform X1 [KO:K06243]
102116149  LAMB3; laminin subunit beta-3 [KO:K06244]
102126627  LAMB4; laminin subunit beta-4 isoform X1 [KO:K06245]
102116045  LAMC1; laminin subunit gamma-1 [KO:K05635]
102116676  LAMC2; laminin subunit gamma-2 [KO:K06246]
102147194  LAMC3; laminin subunit gamma-3 isoform X1 [KO:K06247]
102119232  FN1; fibronectin isoform X2 [KO:K05717]
102133302  ITGA2; integrin alpha-2 isoform X1 [KO:K06481]
102119413  ITGA2B; integrin alpha-IIb isoform X2 [KO:K06476]
102123329  ITGA3; integrin alpha-3 isoform X1 [KO:K06482]
101925271  ITGA6; integrin alpha-6 isoform X3 [KO:K06485]
102116249  ITGAV; integrin alpha-V isoform X1 [KO:K06487]
102144610  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
101925550  PTK2; focal adhesion kinase 1 isoform X6 [KO:K05725] [EC:2.7.10.2]
102143464  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
102142026  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
102122725  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
102137291  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2 [KO:K02649]
101866246  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
102124804  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
101867036  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
102142281  NKX3-1; homeobox protein Nkx-3.1 [KO:K09348]
102144461  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
102142406  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102132744  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102115964  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
102146604  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2 [KO:K07209] [EC:2.7.11.10]
102115368  IKBKG; NF-kappa-B essential modulator isoform X5 [KO:K07210]
101867458  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
102138273  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
102122485  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X3 [KO:K04469]
101867324  RELA; transcription factor p65 isoform X1 [KO:K04735]
102143028  PTGS2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
102121432  NOS2; LOW QUALITY PROTEIN: nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
102138212  BCL2; apoptosis regulator Bcl-2 isoform X2 [KO:K02161]
102137780  baculoviral IAP repeat-containing protein 3 [KO:K16060]
102138168  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
102131393  E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
102126399  LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 8 [KO:K04725] [EC:2.3.2.27]
102121739  BIRC7; baculoviral IAP repeat-containing protein 7 isoform X2 [KO:K16061]
102140222  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
102126034  TRAF1; TNF receptor-associated factor 1 [KO:K03172]
101925175  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
102141355  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
102146475  TRAF4; TNF receptor-associated factor 4 isoform X1 [KO:K09848]
102142772  TRAF5; TNF receptor-associated factor 5 isoform X2 [KO:K09849]
102128596  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
102128371  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
101925564  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X3 [KO:K04688] [EC:2.7.11.1]
102134845  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
102121921  BAD; bcl2-associated agonist of cell death [KO:K02158]
102116712  FOXO1; forkhead box protein O1 [KO:K07201]
102139030  LOW QUALITY PROTEIN: forkhead box protein O1-like [KO:K07201]
102136323  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
102135998  TP53; cellular tumor antigen p53 isoform X2 [KO:K04451]
102117954  CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1 [KO:K06624]
102136063  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
102141928  BCR; breakpoint cluster region protein [KO:K08878] [EC:2.7.11.1]
102115803  ABL1; tyrosine-protein kinase ABL1 isoform X1 [KO:K06619] [EC:2.7.10.2]
102122623  CRKL; crk-like protein [KO:K04438]
101865065  CRK; adapter molecule crk isoform X1 [KO:K04438]
102137660  CBL; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
102120556  signal transducer and activator of transcription 5A [KO:K11223]
102127060  signal transducer and activator of transcription 5B [KO:K11224]
102135814  PIM1; serine/threonine-protein kinase pim-1 [KO:K04702] [EC:2.7.11.1]
101864924  PIM2; serine/threonine-protein kinase pim-2 isoform X1 [KO:K08806] [EC:2.7.11.1]
102124671  KNG1; kininogen-1 [KO:K03898]
102115765  EDN1; endothelin-1 [KO:K16366]
102123453  BDKRB1; B1 bradykinin receptor [KO:K03915]
107126378  BDKRB2; B2 bradykinin receptor [KO:K03916]
101866294  EDNRA; endothelin-1 receptor [KO:K04197]
101925209  EDNRB; endothelin receptor type B [KO:K04198]
102130397  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X1 [KO:K04634]
102123885  GNA11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
101925220  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2 [KO:K05858] [EC:3.1.4.11]
102140615  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
102136896  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
102123165  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
102135875  PRKCA; protein kinase C alpha type isoform X4 [KO:K02677] [EC:2.7.11.13]
102116992  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
101865773  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
102129830  IL2; interleukin-2 [KO:K05429]
102118362  IL3; interleukin-3 [KO:K04736]
107130068  IL4; interleukin-4 [KO:K05430]
102125522  IL5; interleukin-5 [KO:K05428]
102138971  IL6; interleukin-6 precursor [KO:K05405]
102135001  IL7; interleukin-7 isoform X1 [KO:K05431]
102115316  IL12A; interleukin-12 subunit alpha [KO:K05406]
102124858  IL12B; interleukin-12 subunit beta [KO:K05425]
102125887  IL13; interleukin-13 [KO:K05435]
102119613  IL15; interleukin-15 [KO:K05433]
102128555  IL23A; interleukin-23 subunit alpha [KO:K05426]
101925524  EPO; erythropoietin precursor [KO:K05437]
102146717  interferon alpha-17 [KO:K05414]
102140303  interferon alpha-1/13 [KO:K05414]
102140954  IFNA8; interferon alpha-8 [KO:K05414]
102141744  interferon alpha-1/13 [KO:K05414]
102141352  interferon alpha-1/13-like [KO:K05414]
102143043  IFNA6; interferon alpha-6 [KO:K05414]
102144479  interferon alpha-14 [KO:K05414]
102144833  interferon alpha-4-like [KO:K05414]
102145208  interferon alpha-10 [KO:K05414]
102145962  interferon alpha-17 [KO:K05414]
102115289  interferon alpha-17 [KO:K05414]
102142148  IFNA2; interferon alpha-2 [KO:K05414]
123569038  interferon alpha-17-like [KO:K05414]
102146344  interferon alpha-17-like [KO:K05414]
102147079  interferon alpha-17-like [KO:K05414]
102128291  IFNG; interferon gamma [KO:K04687]
102123605  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
102138714  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
102144912  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
102145538  IL3RA; interleukin-3 receptor subunit alpha isoform X1 [KO:K04737]
102133649  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
102143353  CSF2RB; cytokine receptor common subunit beta isoform X2 [KO:K04738]
102115323  IL5RA; interleukin-5 receptor subunit alpha isoform X1 [KO:K05067]
102117292  IL6R; LOW QUALITY PROTEIN: interleukin-6 receptor subunit alpha [KO:K05055]
101926138  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
102143679  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
102143359  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
102131165  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
102135058  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
102121571  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
102133210  IL23R; interleukin-23 receptor [KO:K05065]
102138718  EPOR; erythropoietin receptor [KO:K05079]
101926190  IFNAR1; interferon alpha/beta receptor 1 isoform X3 [KO:K05130]
102140083  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
101866179  IFNGR1; interferon gamma receptor 1 isoform X3 [KO:K05132]
102138221  IFNGR2; interferon gamma receptor 2 [KO:K05133]
102117260  EML4; echinoderm microtubule-associated protein-like 4 isoform X1 [KO:K15420]
102128455  ALK; ALK tyrosine kinase receptor isoform X1 [KO:K05119] [EC:2.7.10.1]
102124752  RASGRP1; RAS guanyl-releasing protein 1 isoform X2 [KO:K04350]
102139509  RASGRP2; RAS guanyl-releasing protein 2 isoform X2 [KO:K12361]
102136095  RASGRP3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
102120963  RASGRP4; RAS guanyl-releasing protein 4 isoform X1 [KO:K12363]
102123983  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
102119008  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
102134669  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
102118402  STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
101925134  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
102133020  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
101925110  STAT4; signal transducer and activator of transcription 4 [KO:K11222]
102117594  STAT6; signal transducer and activator of transcription 6 isoform X1 [KO:K11225]
102140241  VEGFA; vascular endothelial growth factor A isoform X1 [KO:K05448]
102127655  VEGFB; vascular endothelial growth factor B isoform X1 [KO:K16858]
102134620  PGF; placenta growth factor isoform X3 [KO:K16859]
102117741  VEGFC; vascular endothelial growth factor C [KO:K05449]
107126428  VEGFD; vascular endothelial growth factor D [KO:K05449]
102145541  TGFA; protransforming growth factor alpha isoform X2 [KO:K08774]
102123415  EGF; pro-epidermal growth factor isoform X1 [KO:K04357]
102138724  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
102146608  ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
102126620  PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359]
102125183  PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
102138392  PDGFRA; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
101867161  PDGFRB; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
102128018  IGF1; insulin-like growth factor I isoform X1 [KO:K05459]
102126663  IGF2; insulin-like growth factor II isoform X4 [KO:K13769]
102130142  IGF1R; insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
102136326  KITLG; kit ligand isoform X1 [KO:K05461]
102137242  KIT; mast/stem cell growth factor receptor Kit isoform X1 [KO:K05091] [EC:2.7.10.1]
102125470  FLT3LG; fms-related tyrosine kinase 3 ligand isoform X14 [KO:K05454]
102144988  FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X4 [KO:K05092] [EC:2.7.10.1]
102133907  HGF; hepatocyte growth factor isoform X1 [KO:K05460]
102123512  MET; hepatocyte growth factor receptor [KO:K05099] [EC:2.7.10.1]
102134593  FGF1; fibroblast growth factor 1 isoform X1 [KO:K18496]
102133679  FGF2; fibroblast growth factor 2 [KO:K18497]
102127718  FGF22; fibroblast growth factor 22 isoform X2 [KO:K04358]
102141473  FGF18; fibroblast growth factor 18 [KO:K04358]
102131922  FGF7; fibroblast growth factor 7 [KO:K04358]
102146180  FGF5; fibroblast growth factor 5 isoform X1 [KO:K04358]
102137925  FGF17; fibroblast growth factor 17 isoform X1 [KO:K04358]
102120710  FGF6; fibroblast growth factor 6 [KO:K04358]
102140602  FGF8; fibroblast growth factor 8 isoform X1 [KO:K04358]
102138682  FGF20; fibroblast growth factor 20 [KO:K04358]
102134212  FGF3; fibroblast growth factor 3 [KO:K04358]
102134588  FGF4; fibroblast growth factor 4 [KO:K04358]
102121261  FGF16; fibroblast growth factor 16 [KO:K04358]
102143550  FGF10; fibroblast growth factor 10 [KO:K04358]
102140725  FGF9; fibroblast growth factor 9 [KO:K04358]
102134957  FGF19; fibroblast growth factor 19 [KO:K22603]
102126624  FGF21; fibroblast growth factor 21 [KO:K22429]
102120346  FGF23; fibroblast growth factor 23 [KO:K22428]
102144714  FGFR1; fibroblast growth factor receptor 1 isoform X31 [KO:K04362] [EC:2.7.10.1]
102143086  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
102128947  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
102118990  FGFR4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
102118276  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
102135079  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
102138313  SOS2; son of sevenless homolog 2 [KO:K03099]
102118744  HRAS; GTPase HRas isoform X1 [KO:K02833]
102131483  KRAS; GTPase KRas isoform X1 [KO:K07827]
102137913  NRAS; GTPase NRas [KO:K07828]
101925249  ARAF; serine/threonine-protein kinase A-Raf isoform X1 [KO:K08845] [EC:2.7.11.1]
101866436  BRAF; serine/threonine-protein kinase B-raf isoform X4 [KO:K04365] [EC:2.7.11.1]
102125312  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
102141214  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
102140855  dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
102145011  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
102116996  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
102126446  JUN; transcription factor AP-1 [KO:K04448]
102143716  FOS; proto-oncogene c-Fos [KO:K04379]
102131296  ETS1; protein C-ets-1 isoform X6 [KO:K02678]
102142258  MMP1; interstitial collagenase [KO:K01388] [EC:3.4.24.7]
101865544  MMP2; 72 kDa type IV collagenase [KO:K01398] [EC:3.4.24.24]
102117693  MMP9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
102127272  CXCL8; interleukin-8 [KO:K10030]
101925733  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
102137672  RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
102135879  RET; proto-oncogene tyrosine-protein kinase receptor Ret [KO:K05126] [EC:2.7.10.1]
102131341  CCDC6; coiled-coil domain-containing protein 6 [KO:K09288]
101865675  NCOA4; nuclear receptor coactivator 4 isoform X1 [KO:K09289]
102129364  NTRK1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
101925252  TPM3; tropomyosin alpha-3 chain isoform X3 [KO:K09290]
102143897  tropomyosin alpha-3 chain-like [KO:K09290]
102138786  TPR; nucleoprotein TPR isoform X1 [KO:K09291]
101867069  TFG; protein TFG isoform X1 [KO:K09292]
102144868  RASSF1; ras association domain-containing protein 1 isoform X2 [KO:K09850]
102127304  RASSF5; ras association domain-containing protein 5 isoform X1 [KO:K08015]
102115733  STK4; serine/threonine-protein kinase 4 isoform X1 [KO:K04411]
102133584  DAPK2; death-associated protein kinase 2 isoform X2 [KO:K08803] [EC:2.7.11.1]
102114785  DAPK1; death-associated protein kinase 1 isoform X2 [KO:K08803] [EC:2.7.11.1]
102138834  DAPK3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
102138726  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
102117471  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
102146168  ELK1; ETS domain-containing protein Elk-1 [KO:K04375]
102131144  ETS domain-containing protein Elk-1-like [KO:K04375]
102137357  ETS domain-containing protein Elk-1-like [KO:K04375]
102119159  CALML6; calmodulin-like protein 6 [KO:K02183]
102114795  CALML3; calmodulin-like protein 3 [KO:K02183]
102146976  CALML5; calmodulin-like protein 5 [KO:K02183]
102131162  CALM1; calmodulin-1 [KO:K02183]
101866377  CALM3; calmodulin-3 [KO:K02183]
101865168  CALM2; calmodulin-2 [KO:K02183]
102122343  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
102144138  calmodulin-1 [KO:K02183]
101926613  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
102126681  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
101865637  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
101866326  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
102121408  RALGDS; ral guanine nucleotide dissociation stimulator isoform X3 [KO:K08732]
102124288  ral-GDS-related protein-like isoform X1 [KO:K08732]
102125458  LOW QUALITY PROTEIN: ral-GDS-related protein-like [KO:K08732]
102124292  RALA; ras-related protein Ral-A [KO:K07834]
101925782  RALB; ras-related protein Ral-B [KO:K07835]
102128258  RALBP1; ralA-binding protein 1 isoform X1 [KO:K08773]
101925934  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
102125726  cell division control protein 42 homolog [KO:K04393]
102124817  cell division control protein 42 homolog [KO:K04393]
101866593  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
102134837  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
102137056  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
102143597  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
102132109  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
102130012  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
102118497  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
102126339  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
102121272  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
102128714  PAX8; paired box protein Pax-8 isoform X1 [KO:K09293]
102120453  PPARG; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
102133330  RXRA; retinoic acid receptor RXR-alpha isoform X1 [KO:K08524]
102132522  RXRB; retinoic acid receptor RXR-beta isoform X1 [KO:K08525]
101864810  RXRG; retinoic acid receptor RXR-gamma isoform X1 [KO:K08526]
102128641  RARB; retinoic acid receptor beta isoform X1 [KO:K08528]
102115223  ESR1; estrogen receptor isoform X1 [KO:K08550]
102143451  ESR2; estrogen receptor beta isoform X1 [KO:K08551]
101925525  NCOA1; nuclear receptor coactivator 1 isoform X1 [KO:K09101] [EC:2.3.1.48]
102145890  NCOA3; nuclear receptor coactivator 3 isoform X1 [KO:K11256] [EC:2.3.1.48]
102115996  SP1; transcription factor Sp1 isoform X1 [KO:K04684]
102125360  PPARD; peroxisome proliferator-activated receptor delta isoform X2 [KO:K04504]
102136550  junction plakoglobin [KO:K10056]
102128204  ZBTB16; zinc finger and BTB domain-containing protein 16 [KO:K10055]
102132722  RARA; retinoic acid receptor alpha isoform X1 [KO:K08527]
102122434  CCNA2; cyclin-A2 [KO:K06627]
101926559  CCNA1; cyclin-A1 isoform X1 [KO:K06627]
102135847  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
102145008  RUNX1; runt-related transcription factor 1 isoform X1 [KO:K08367]
102118526  RUNX1T1; LOW QUALITY PROTEIN: protein CBFA2T1 [KO:K10053]
102140931  SPI1; transcription factor PU.1 isoform X1 [KO:K09438]
102119204  CEBPA; CCAAT/enhancer-binding protein alpha [KO:K09055]
102139775  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha [KO:K05066]
102132219  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
102124214  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
102135474  tumor suppressor ARF isoform X1 [KO:K06621]
102146018  E2F1; transcription factor E2F1 [KO:K17454]
102128093  E2F2; transcription factor E2F2 isoform X1 [KO:K09389]
102138138  E2F3; transcription factor E2F3 isoform X1 [KO:K06620]
101866471  MAX; protein max isoform X1 [KO:K04453]
102118903  ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 [KO:K10500]
101866825  CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685]
102140874  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
102119572  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
101865999  CCND3; G1/S-specific cyclin-D3 isoform X2 [KO:K10152]
102142394  CKS1B; cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
102128865  CKS2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
123568000  cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
123568656  cyclin-dependent kinases regulatory subunit 1-like [KO:K02219]
102142637  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
123569073  S-phase kinase-associated protein 1-like [KO:K03094]
102119803  S-phase kinase-associated protein 1-like isoform X1 [KO:K03094]
101867010  CUL1; cullin-1 [KO:K03347]
102132483  RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1 [KO:K03868] [EC:2.3.2.32]
102114882  SKP2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
102139233  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
102138564  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
102137714  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
102145859  RB1; retinoblastoma-associated protein isoform X1 [KO:K06618]
102128083  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
102135480  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
102115080  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
102132255  BAX; apoptosis regulator BAX isoform X6 [KO:K02159]
102142357  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
102124623  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
101925142  POLK; DNA polymerase kappa isoform X2 [KO:K03511] [EC:2.7.7.7]
102141055  TERT; telomerase reverse transcriptase isoform X3 [KO:K11126] [EC:2.7.7.49]
102121325  MITF; microphthalmia-associated transcription factor isoform X1 [KO:K09455]
102129546  TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
101925182  TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
102119907  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
102115287  TGFBR1; TGF-beta receptor type-1 isoform X3 [KO:K04674] [EC:2.7.11.30]
102134273  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
101925163  SMAD2; mothers against decapentaplegic homolog 2 isoform X5 [KO:K04500]
102146086  SMAD3; mothers against decapentaplegic homolog 3 isoform X2 [KO:K23605]
102142438  SMAD4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
102139452  MECOM; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
102121365  CTBP1; C-terminal-binding protein 1 isoform X3 [KO:K04496] [EC:1.1.1.428]
102117103  CTBP2; C-terminal-binding protein 2 isoform X1 [KO:K04496] [EC:1.1.1.428]
102127640  LOW QUALITY PROTEIN: C-terminal-binding protein 2-like [KO:K04496] [EC:1.1.1.428]
102125039  HDAC1; histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
102140882  HDAC2; histone deacetylase 2 isoform X1 [KO:K06067] [EC:3.5.1.98]
102125090  LOW QUALITY PROTEIN: histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
102121501  LOW QUALITY PROTEIN: histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
102132397  LOW QUALITY PROTEIN: histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
102132986  MLH1; DNA mismatch repair protein Mlh1 isoform X1 [KO:K08734]
101867487  MSH2; DNA mismatch repair protein Msh2 [KO:K08735]
102136760  MSH3; DNA mismatch repair protein Msh3 isoform X1 [KO:K08736]
102143419  MSH6; DNA mismatch repair protein Msh6 isoform X1 [KO:K08737]
102140332  BRCA2; breast cancer type 2 susceptibility protein isoform X2 [KO:K08775]
102115932  RAD51; DNA repair protein RAD51 homolog 1 isoform X2 [KO:K04482]
102139406  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
101866285  FADD; FAS-associated death domain protein [KO:K02373]
101865354  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
102143226  BID; BH3-interacting domain death agonist isoform X2 [KO:K04726]
102120192  PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1 isoform X2 [KO:K10131]
102119825  BBC3; bcl-2-binding component 3 isoform X3 [KO:K10132]
102135074  BCL2L11; bcl-2-like protein 11 isoform X5 [KO:K16341]
102117102  cytochrome c-like [KO:K08738]
102120205  cytochrome c [KO:K08738]
102125088  cytochrome c-like [KO:K08738]
102136392  cytochrome c-like [KO:K08738]
102127614  cytochrome c-like [KO:K08738]
102141866  cytochrome c-like [KO:K08738]
107127908  cytochrome c-like [KO:K08738]
102120841  cytochrome c-like [KO:K08738]
102123704  cytochrome c-like [KO:K08738]
107130218  cytochrome c-like [KO:K08738]
102137473  APAF1; apoptotic protease-activating factor 1 [KO:K02084]
102127213  CASP7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
102118980  KEAP1; kelch-like ECH-associated protein 1 [KO:K10456]
102138754  NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X2 [KO:K05638]
101926565  HMOX1; heme oxygenase 1 isoform X1 [KO:K00510] [EC:1.14.14.18]
102121489  NQO1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
102138414  MGST3; microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
102115229  glutathione S-transferase A1 [KO:K00799] [EC:2.5.1.18]
101866044  MGST2; microsomal glutathione S-transferase 2 isoform X1 [KO:K00799] [EC:2.5.1.18]
101865382  GSTA4; glutathione S-transferase A4 isoform X1 [KO:K00799] [EC:2.5.1.18]
102146648  MGST1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
102117319  GSTO1; glutathione S-transferase omega-1 isoform X2 [KO:K00799] [EC:2.5.1.18]
102116720  GSTO2; glutathione S-transferase omega-2 isoform X1 [KO:K00799] [EC:2.5.1.18]
102142224  GSTT2B; glutathione S-transferase theta-2B [KO:K00799] [EC:2.5.1.18]
102114846  glutathione S-transferase A3 isoform X1 [KO:K00799] [EC:2.5.1.18]
102145837  GSTM4; glutathione S-transferase Mu 1 isoform X1 [KO:K00799] [EC:2.5.1.18]
102146042  glutathione S-transferase A5 [KO:K00799] [EC:2.5.1.18]
101925101  GSTM5; glutathione S-transferase Mu 5 [KO:K00799] [EC:2.5.1.18]
102145210  GSTM3; glutathione S-transferase Mu 3 isoform X1 [KO:K00799] [EC:2.5.1.18]
102146720  GSTM2; glutathione S-transferase Mu 2 isoform X1 [KO:K00799] [EC:2.5.1.18]
102142998  glutathione S-transferase theta-1 isoform X4 [KO:K00799] [EC:2.5.1.18]
102130209  glutathione S-transferase omega-1-like [KO:K00799] [EC:2.5.1.18]
102120066  LOW QUALITY PROTEIN: glutathione S-transferase Mu 1-like [KO:K00799] [EC:2.5.1.18]
123572957  glutathione S-transferase A1 [KO:K00799] [EC:2.5.1.18]
123572960  glutathione S-transferase A4-like [KO:K00799] [EC:2.5.1.18]
102140658  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
102143668  glutathione S-transferase theta-4-like [KO:K00799] [EC:2.5.1.18]
102127415  GSTP1; glutathione S-transferase P [KO:K23790] [EC:2.5.1.18]
102122910  TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X6 [KO:K22182] [EC:1.8.1.9]
102140994  TXNRD3; thioredoxin reductase 3 isoform X6 [KO:K22182] [EC:1.8.1.9]
102146500  TXNRD2; thioredoxin reductase 2, mitochondrial isoform X3 [KO:K22182] [EC:1.8.1.9]
107128974  VHL; von Hippel-Lindau disease tumor suppressor isoform X1 [KO:K03871]
101926366  ELOC; elongin-C isoform X1 [KO:K03872]
102116941  elongin-C-like [KO:K03872]
101926586  ELOB; elongin-B [KO:K03873]
102145828  elongin-B-like [KO:K03873]
123575297  elongin-B-like [KO:K03873]
102118914  CUL2; cullin-2 [KO:K03870]
102128342  EGLN1; egl nine homolog 1 isoform X1 [KO:K09592] [EC:1.14.11.29]
101865926  EGLN3; prolyl hydroxylase EGLN3 [KO:K09592] [EC:1.14.11.29]
102119819  EGLN2; prolyl hydroxylase EGLN2 isoform X1 [KO:K09592] [EC:1.14.11.29]
102118371  FH; fumarate hydratase, mitochondrial [KO:K01679] [EC:4.2.1.2]
101866092  HIF1A; hypoxia-inducible factor 1-alpha [KO:K08268]
102124613  EPAS1; endothelial PAS domain-containing protein 1 [KO:K09095]
102118770  ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097]
101925178  ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1 [KO:K15589]
102131731  EP300; histone acetyltransferase p300 isoform X2 [KO:K04498] [EC:2.3.1.48]
102135037  CREB-binding protein isoform X2 [KO:K04498] [EC:2.3.1.48]
102144217  SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
102132875  JAG1; protein jagged-1 isoform X1 [KO:K06052]
102119283  JAG2; protein jagged-2 isoform X1 [KO:K21635]
102145271  DLL1; delta-like protein 1 [KO:K06051]
102125764  DLL4; delta-like protein 4 [KO:K06051]
102115332  DLL3; delta-like protein 3 isoform X1 [KO:K06051]
102138307  NOTCH1; neurogenic locus notch homolog protein 1 isoform X1 [KO:K02599]
101864989  NOTCH2; neurogenic locus notch homolog protein 2 isoform X1 [KO:K20994]
102120202  NOTCH3; neurogenic locus notch homolog protein 3 [KO:K20995]
101866845  NOTCH4; neurogenic locus notch homolog protein 4 isoform X5 [KO:K20996]
102146862  HES1; transcription factor HES-1 [KO:K06054]
102143983  HES5; transcription factor HES-5 isoform X1 [KO:K06055]
102133602  HEYL; hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091]
102121748  HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 [KO:K09091]
102137167  HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1 [KO:K09091]
102123168  FLT4; vascular endothelial growth factor receptor 3 isoform X1 [KO:K05097] [EC:2.7.10.1]
102120970  SHH; sonic hedgehog protein [KO:K11988]
102121818  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
102121742  SMO; smoothened homolog isoform X1 [KO:K06226]
102141888  KIF7; kinesin-like protein KIF7 isoform X6 [KO:K18806]
102129406  SUFU; suppressor of fused homolog isoform X1 [KO:K06229]
102136450  GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797]
102125979  GLI2; zinc finger protein GLI2 isoform X1 [KO:K16798]
102145019  GLI3; transcriptional activator GLI3 isoform X3 [KO:K06230]
102145501  BMP2; bone morphogenetic protein 2 [KO:K21283]
102132568  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
102131133  hedgehog-interacting protein isoform X1 [KO:K06231]
102130537  PTCH2; protein patched homolog 2 isoform X9 [KO:K11101]
102117720  AR; androgen receptor isoform X1 [KO:K08557]
101926380  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
102123807  LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like [KO:K04079]
101866865  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
101926487  HSP90B1; endoplasmin [KO:K09487]
102136375  LOW QUALITY PROTEIN: endoplasmin-like [KO:K09487]
102138599  prostate-specific antigen isoform X5 [KO:K01351] [EC:3.4.21.77]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
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PMID:17251915
  Authors
Dorsam RT, Gutkind JS
  Title
G-protein-coupled receptors and cancer.
  Journal
Nat Rev Cancer 7:79-94 (2007)
DOI:10.1038/nrc2069
Related
pathway
mcf03320  PPAR signaling pathway
mcf04010  MAPK signaling pathway
mcf04020  Calcium signaling pathway
mcf04024  cAMP signaling pathway
mcf04060  Cytokine-cytokine receptor interaction
mcf04066  HIF-1 signaling pathway
mcf04110  Cell cycle
mcf04115  p53 signaling pathway
mcf04150  mTOR signaling pathway
mcf04151  PI3K-Akt signaling pathway
mcf04210  Apoptosis
mcf04310  Wnt signaling pathway
mcf04330  Notch signaling pathway
mcf04340  Hedgehog signaling pathway
mcf04350  TGF-beta signaling pathway
mcf04370  VEGF signaling pathway
mcf04510  Focal adhesion
mcf04512  ECM-receptor interaction
mcf04520  Adherens junction
mcf04630  JAK-STAT signaling pathway
mcf04915  Estrogen signaling pathway
KO pathway
ko05200   
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