KEGG   PATHWAY: mmyo05200
Entry
mmyo05200                   Pathway                                
Name
Pathways in cancer - Myotis myotis (greater mouse-eared bat)
Class
Human Diseases; Cancer: overview
Pathway map
mmyo05200  Pathways in cancer
mmyo05200

Organism
Myotis myotis (greater mouse-eared bat) [GN:mmyo]
Gene
118663207  DCC; netrin receptor DCC [KO:K06765]
118650210  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
118677148  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
118667962  APPL1; DCC-interacting protein 13-alpha isoform X1 [KO:K08733]
118674502  CDH1; cadherin-1 isoform X1 [KO:K05689]
118668371  CTNNB1; catenin beta-1 isoform X1 [KO:K02105]
118658375  CTNNA1; catenin alpha-1 isoform X1 [KO:K05691]
118668808  CTNNA2; catenin alpha-2 isoform X1 [KO:K05691]
118670057  CTNNA3; catenin alpha-3 [KO:K05691]
118652848  AXIN1; axin-1 isoform X1 [KO:K02157]
118654322  LOW QUALITY PROTEIN: axin-1-like [KO:K02157]
118671617  AXIN2; axin-2 isoform X1 [KO:K04385]
118658707  APC2; adenomatous polyposis coli protein 2 isoform X1 [KO:K02085]
118655759  APC; adenomatous polyposis coli protein isoform X1 [KO:K02085]
118675932  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
118657631  TCF7; transcription factor 7 isoform X1 [KO:K02620]
118668800  TCF7L1; transcription factor 7-like 1 isoform X1 [KO:K04490]
118669739  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
118673131  LEF1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
118671120  BIRC5; baculoviral IAP repeat-containing protein 5 [KO:K08731]
118664013  baculoviral IAP repeat-containing protein 5-like [KO:K08731]
118670599  MYC; myc proto-oncogene protein [KO:K04377]
118665181  CCND1; G1/S-specific cyclin-D1 isoform X1 [KO:K04503]
118650977  WNT1; proto-oncogene Wnt-1 [KO:K03209]
118672911  WNT2B; protein Wnt-2b [KO:K00182]
118666478  WNT2; protein Wnt-2 [KO:K00182]
118658755  WNT3A; protein Wnt-3a isoform X1 [KO:K00312]
118672219  WNT3; proto-oncogene Wnt-3 isoform X1 [KO:K00312]
118676694  WNT4; protein Wnt-4 [KO:K00408]
118650248  WNT5B; protein Wnt-5b [KO:K00444]
118667971  WNT5A; protein Wnt-5a [KO:K00444]
118662211  WNT6; protein Wnt-6 [KO:K00445]
118650243  WNT7B; protein Wnt-7b isoform X1 [KO:K00572]
118677354  WNT7A; protein Wnt-7a [KO:K00572]
118658912  WNT8A; protein Wnt-8a [KO:K00714]
118669850  WNT8B; protein Wnt-8b [KO:K00714]
118658374  WNT9A; protein Wnt-9a [KO:K01064]
118671436  WNT9B; protein Wnt-9b [KO:K01064]
118651671  WNT10B; protein Wnt-10b [KO:K01357]
118661959  WNT10A; protein Wnt-10a isoform X1 [KO:K01357]
118664619  WNT11; protein Wnt-11 [KO:K01384]
118666468  WNT16; protein Wnt-16 isoform X1 [KO:K01558]
118666245  FZD1; frizzled-1 [KO:K02432]
118661773  FZD7; frizzled-7 [KO:K02432]
118672294  FZD2; frizzled-2 [KO:K02235]
118658774  FZD3; frizzled-3 isoform X1 [KO:K02329]
118664546  FZD4; frizzled-4 [KO:K02354]
118661425  FZD5; frizzled-5 [KO:K02375]
118676314  FZD8; frizzled-8 [KO:K02375]
118670703  FZD6; frizzled-6 [KO:K02376]
118653033  FZD10; LOW QUALITY PROTEIN: frizzled-10 [KO:K02842]
118656623  FZD9; frizzled-9 [KO:K02842]
118649950  LRP6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
118665196  LRP5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068]
118677642  DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353]
118655561  DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353]
118672041  DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353]
118669908  FRAT1; proto-oncogene FRAT1 [KO:K03069]
118669907  FRAT2; GSK-3-binding protein FRAT2 [KO:K03096]
118650448  LOW QUALITY PROTEIN: prothrombin-like [KO:K01313] [EC:3.4.21.5]
118665076  F2; prothrombin [KO:K01313] [EC:3.4.21.5]
118678933  AGT; angiotensinogen [KO:K09821]
118656246  F2R; proteinase-activated receptor 1 isoform X1 [KO:K03914]
118652564  F2RL3; LOW QUALITY PROTEIN: proteinase-activated receptor 4 [KO:K04236]
118667192  LPAR1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
118657971  LPAR2; lysophosphatidic acid receptor 2 isoform X1 [KO:K04291]
118676951  LPAR3; lysophosphatidic acid receptor 3 [KO:K04294]
118654701  LPAR4; lysophosphatidic acid receptor 4 [KO:K04275]
118651359  LPAR5; lysophosphatidic acid receptor 5 [KO:K08390]
118651070  LPAR6; lysophosphatidic acid receptor 6 [KO:K04273]
118677044  AGTR1; type-1 angiotensin II receptor [KO:K04166]
118657873  GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346]
118671564  GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
118657355  ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
118672913  ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1 [KO:K12331]
118674379  ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
118653515  LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 5-like [KO:K19464]
118653521  LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 5-like [KO:K19464]
118675436  PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1 [KO:K19464]
118675634  LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 5-like [KO:K19464]
118668483  RHOA; transforming protein RhoA [KO:K04513]
118664539  transforming protein RhoA-like isoform X1 [KO:K04513]
118662528  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
118669273  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
118679334  CXCL12; stromal cell-derived factor 1 isoform X1 [KO:K10031]
118661864  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
118666051  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630]
118673502  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha isoform X1 [KO:K04630]
118668456  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
118675794  guanine nucleotide-binding protein G(i) subunit alpha-like [KO:K04630]
118652697  PTGER1; prostaglandin E2 receptor EP1 subtype isoform X1 [KO:K04258]
118655337  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
118675132  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
118656159  PTGER4; prostaglandin E2 receptor EP4 subtype [KO:K04261]
118662565  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
118663143  neuroendocrine secretory protein 55-like [KO:K04632]
118665883  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
118656192  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
118669221  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
118678616  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
118676734  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
118650262  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
118674005  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
118670715  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
118656939  ADCY9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
118652717  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
118675444  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
118655599  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
118655733  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
118649724  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
118676150  GNB4; guanine nucleotide-binding protein subunit beta-4 isoform X1 [KO:K04538]
118651993  GNB5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
118655246  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X1 [KO:K07826]
118648957  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
118678724  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
118666631  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
118673940  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
118653683  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
118661166  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
118663367  LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
118675273  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
118658681  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
118652811  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
118658043  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
118667187  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
118666214  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
118652667  GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 isoform X1 [KO:K04347]
118677067  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
118652936  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
118666579  guanine nucleotide-binding protein G(T) subunit gamma-T1-like [KO:K04548]
118672316  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
118651398  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
118651399  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
118654149  COL4A6; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
118654373  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
118661805  COL4A4; collagen alpha-4(IV) chain isoform X1 [KO:K06237]
118661915  COL4A3; collagen alpha-3(IV) chain [KO:K06237]
118659861  LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637]
118663257  LAMA1; laminin subunit alpha-1 [KO:K05637]
118662808  LAMA3; laminin subunit alpha-3 isoform X1 [KO:K06240]
118663687  LAMA5; laminin subunit alpha-5 [KO:K06240]
118660060  LAMA4; laminin subunit alpha-4 isoform X1 [KO:K06241]
118665985  LAMB1; laminin subunit beta-1 isoform X1 [KO:K05636]
118668489  LAMB2; laminin subunit beta-2 isoform X1 [KO:K06243]
118672717  LAMB3; laminin subunit beta-3 isoform X1 [KO:K06244]
118665984  LAMB4; laminin subunit beta-4 isoform X1 [KO:K06245]
118672671  LAMC1; laminin subunit gamma-1 [KO:K05635]
118672978  LAMC2; laminin subunit gamma-2 isoform X1 [KO:K06246]
118666951  LAMC3; laminin subunit gamma-3 [KO:K06247]
118661269  FN1; fibronectin isoform X1 [KO:K05717]
118655743  ITGA2; integrin alpha-2 isoform X1 [KO:K06481]
118671403  ITGA2B; integrin alpha-IIb isoform X1 [KO:K06476]
118671288  ITGA3; integrin alpha-3 [KO:K06482]
118661789  ITGA6; integrin alpha-6 isoform X1 [KO:K06485]
118661050  ITGAV; integrin alpha-V isoform X1 [KO:K06487]
118676628  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
118670566  PTK2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
118677590  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
118668125  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
118675045  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
118675217  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
118656203  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
118657573  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
118677363  LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
118670001  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
118657560  NKX3-1; homeobox protein Nkx-3.1 [KO:K09348]
118678909  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
118655031  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
118674834  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
118669852  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
118650776  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
118653690  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
118677878  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
118671867  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
118669805  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
118665292  RELA; transcription factor p65 [KO:K04735]
118673371  PTGS2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
118672123  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
118663765  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
118677457  LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 2-like [KO:K16060]
118664470  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
118664472  baculoviral IAP repeat-containing protein 3-like [KO:K16060]
118653756  E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
118663066  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
118667115  TRAF1; TNF receptor-associated factor 1 isoform X1 [KO:K03172]
118655263  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
118655021  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
118671843  TRAF4; TNF receptor-associated factor 4 [KO:K09848]
118672932  TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
118665127  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
118675322  MTOR; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
118649569  LOW QUALITY PROTEIN: ribosomal protein S6 kinase beta-2-like [KO:K04688] [EC:2.7.11.1]
118649570  ribosomal protein S6 kinase beta-2-like [KO:K04688] [EC:2.7.11.1]
118671643  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
118665219  RPS6KB2; ribosomal protein S6 kinase beta-2 [KO:K04688] [EC:2.7.11.1]
118665363  BAD; bcl2-associated agonist of cell death [KO:K02158]
118649960  FOXO1; forkhead box protein O1 [KO:K07201]
118650326  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
118672084  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
118650327  CDKN1B; cyclin-dependent kinase inhibitor 1B [KO:K06624]
118659964  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
118655515  BCR; breakpoint cluster region protein [KO:K08878] [EC:2.7.11.1]
118666952  ABL1; tyrosine-protein kinase ABL1 isoform X1 [KO:K06619] [EC:2.7.10.2]
118678200  CRKL; crk-like protein isoform X1 [KO:K04438]
118671896  CRK; adapter molecule crk isoform X1 [KO:K04438]
118664184  CBL; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
118671506  STAT5A; signal transducer and activator of transcription 5A isoform X1 [KO:K11223]
118671504  signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
118660128  PIM1; serine/threonine-protein kinase pim-1 [KO:K04702] [EC:2.7.11.1]
118653740  PIM2; serine/threonine-protein kinase pim-2 isoform X1 [KO:K08806] [EC:2.7.11.1]
118675748  LOW QUALITY PROTEIN: kininogen-1-like [KO:K03898]
118675750  kininogen-2-like [KO:K03898]
118676365  KNG1; kininogen-1 [KO:K03898]
118677109  EDN1; endothelin-1 isoform X1 [KO:K16366]
118660407  BDKRB1; B1 bradykinin receptor [KO:K03915]
118660405  BDKRB2; B2 bradykinin receptor [KO:K03916]
118658387  EDNRA; endothelin-1 receptor isoform X1 [KO:K04197]
118651235  EDNRB; endothelin receptor type B [KO:K04198]
118667437  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
118658361  GNA11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
118649794  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
118663015  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
118663147  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
118665361  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
118671569  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
118655815  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
118660957  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
118658725  IL2; interleukin-2 [KO:K05429]
118657905  IL4; interleukin-4 [KO:K05430]
118658442  IL5; interleukin-5 [KO:K05428]
118666134  IL6; interleukin-6 [KO:K05405]
118671020  IL7; interleukin-7 isoform X1 [KO:K05431]
118675787  IL12A; interleukin-12 subunit alpha [KO:K05406]
118659025  IL12B; interleukin-12 subunit beta [KO:K05425]
118659168  IL13; interleukin-13 [KO:K05435]
118658401  IL15; interleukin-15 isoform X1 [KO:K05433]
118651144  IL23A; interleukin-23 subunit alpha [KO:K05426]
118657054  EPO; erythropoietin [KO:K05437]
118667586  interferon omega-1-like [KO:K05414]
118651276  IFNG; interferon gamma [KO:K04687]
118672311  IL2RA; interleukin-2 receptor subunit alpha [KO:K05068]
118651872  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
118661694  METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X1 [KO:K05070]
118654549  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
118657316  IL3RA; interleukin-3 receptor subunit alpha isoform X1 [KO:K04737]
118652869  interleukin-4 receptor subunit alpha-like isoform X1 [KO:K05071]
118656213  interleukin-4 receptor subunit alpha-like isoform X1 [KO:K05071]
118651099  CSF2RB; cytokine receptor common subunit beta [KO:K04738]
118668400  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
118672712  IL6R; interleukin-6 receptor subunit alpha isoform X1 [KO:K05055]
118655807  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
118656297  IL7R; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
118659126  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
118676249  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
118653704  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
118672325  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
118677052  IL23R; interleukin-23 receptor [KO:K05065]
118659055  EPOR; erythropoietin receptor isoform X1 [KO:K05079]
118676057  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
118676213  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
118659706  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
118675501  IFNGR2; interferon gamma receptor 2 [KO:K05133]
118669063  EML4; echinoderm microtubule-associated protein-like 4 isoform X1 [KO:K15420]
118669138  ALK tyrosine kinase receptor-like [KO:K05119] [EC:2.7.10.1]
118649584  RASGRP1; RAS guanyl-releasing protein 1 isoform X1 [KO:K04350]
118665351  RASGRP2; RAS guanyl-releasing protein 2 isoform X1 [KO:K12361]
118669112  RASGRP3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
118674089  RASGRP4; RAS guanyl-releasing protein 4 isoform X1 [KO:K12363]
118675339  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
118667512  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
118658721  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
118671501  STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
118661220  STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
118651142  STAT2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
118661772  STAT4; signal transducer and activator of transcription 4 isoform X1 [KO:K11222]
118650227  STAT6; signal transducer and activator of transcription 6 isoform X1 [KO:K11225]
118660010  VEGFA; vascular endothelial growth factor A [KO:K05448]
118665372  VEGFB; vascular endothelial growth factor B isoform X1 [KO:K16858]
118658139  PGF; placenta growth factor isoform X1 [KO:K16859]
118651245  VEGFC; vascular endothelial growth factor C [KO:K05449]
118654158  VEGFD; vascular endothelial growth factor D isoform X1 [KO:K05449]
118668883  TGFA; protransforming growth factor alpha isoform X1 [KO:K08774]
118672981  EGF; pro-epidermal growth factor [KO:K04357]
118665909  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
118671218  ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
118658213  PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359]
118651562  PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
118668634  PDGFRA; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
118658697  PDGFRB; platelet-derived growth factor receptor beta isoform X1 [KO:K05089] [EC:2.7.10.1]
118651145  IGF1; insulin-like growth factor I isoform X1 [KO:K05459]
118659613  IGF2; insulin-like growth factor II [KO:K13769]
118679204  IGF1R; insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
118650035  KITLG; kit ligand isoform X1 [KO:K05461]
118668862  KIT; mast/stem cell growth factor receptor Kit isoform X1 [KO:K05091] [EC:2.7.10.1]
118655367  FLT3LG; fms-related tyrosine kinase 3 ligand isoform X1 [KO:K05454]
118651974  FLT3; receptor-type tyrosine-protein kinase FLT3 [KO:K05092] [EC:2.7.10.1]
118666274  HGF; hepatocyte growth factor isoform X1 [KO:K05460]
118666481  MET; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
118658742  FGF1; fibroblast growth factor 1 isoform X1 [KO:K18496]
118657980  FGF2; fibroblast growth factor 2 [KO:K18497]
118651638  FGF7; fibroblast growth factor 7 [KO:K04358]
118649770  FGF6; fibroblast growth factor 6 [KO:K04358]
118651170  FGF20; fibroblast growth factor 20 [KO:K04358]
118657925  FGF22; fibroblast growth factor 22 isoform X1 [KO:K04358]
118657946  FGF18; fibroblast growth factor 18 isoform X1 [KO:K04358]
118658335  FGF17; fibroblast growth factor 17 isoform X1 [KO:K04358]
118651945  FGF9; fibroblast growth factor 9 isoform X1 [KO:K04358]
118653962  FGF5; fibroblast growth factor 5 isoform X1 [KO:K04358]
118654722  FGF16; fibroblast growth factor 16 [KO:K04358]
118670266  FGF8; fibroblast growth factor 8 isoform X1 [KO:K04358]
118664022  FGF3; fibroblast growth factor 3 [KO:K04358]
118664023  FGF4; fibroblast growth factor 4 [KO:K04358]
118656661  FGF10; fibroblast growth factor 10 [KO:K04358]
118664060  FGF19; fibroblast growth factor 19 [KO:K22603]
118655446  FGF21; fibroblast growth factor 21 [KO:K22429]
118651326  FGF23; fibroblast growth factor 23 [KO:K22428]
118649562  FGFR1; fibroblast growth factor receptor 1 isoform X1 [KO:K04362] [EC:2.7.10.1]
118655613  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
118665364  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
118659099  FGFR4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
118671153  GRB2; growth factor receptor-bound protein 2 isoform X1 [KO:K04364]
118669078  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
118654741  SOS2; son of sevenless homolog 2 isoform X1 [KO:K03099]
118648965  HRAS; GTPase HRas isoform X1 [KO:K02833]
118649554  KRAS; GTPase KRas isoform X1 [KO:K07827]
118672986  NRAS; GTPase NRas [KO:K07828]
118653778  ARAF; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
118666337  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
118668076  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
118654213  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
118657986  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
118678650  MAPK1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
118656605  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
118676104  JUN; transcription factor AP-1 [KO:K04448]
118658230  FOS; proto-oncogene c-Fos [KO:K04379]
118678133  ETS1; protein C-ets-1 isoform X1 [KO:K02678]
118664460  MMP1; interstitial collagenase [KO:K01388] [EC:3.4.24.7]
118674505  MMP2; 72 kDa type IV collagenase [KO:K01398] [EC:3.4.24.24]
118663534  MMP9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
118670543  CXCL8; interleukin-8 [KO:K10030]
118671044  C-X-C motif chemokine 15-like [KO:K10030]
118651037  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
118659250  RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
118670212  RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [KO:K05126] [EC:2.7.10.1]
118670033  CCDC6; coiled-coil domain-containing protein 6 [KO:K09288]
118679305  NCOA4; nuclear receptor coactivator 4 isoform X1 [KO:K09289]
118673526  NTRK1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
118672903  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
118657297  LOW QUALITY PROTEIN: tropomyosin alpha-3 chain-like [KO:K09290]
118664998  tropomyosin alpha-3 chain-like [KO:K09290]
118673090  TPR; nucleoprotein TPR isoform X1 [KO:K09291]
118675256  TFG; protein TFG isoform X1 [KO:K09292]
118668448  RASSF1; LOW QUALITY PROTEIN: ras association domain-containing protein 1 [KO:K09850]
118672789  RASSF5; ras association domain-containing protein 5 isoform X1 [KO:K08015]
118663625  STK4; serine/threonine-protein kinase 4 isoform X1 [KO:K04411]
118658400  DAPK3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
118667408  death-associated protein kinase 1 isoform X1 [KO:K08803] [EC:2.7.11.1]
118653501  DAPK2; death-associated protein kinase 2 isoform X1 [KO:K08803] [EC:2.7.11.1]
118662889  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
118674206  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
118653890  ELK1; ETS domain-containing protein Elk-1 isoform X1 [KO:K04375]
118665751  calmodulin-alpha-like isoform X1 [KO:K02183]
118677428  calmodulin-like [KO:K02183]
118658241  neo-calmodulin-like [KO:K02183]
118659208  CALM1; calmodulin-1 [KO:K02183]
118652797  CALM3; calmodulin-3 [KO:K02183]
118669030  CALM2; calmodulin-2 [KO:K02183]
118654466  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
118655601  CALML6; calmodulin-like protein 6 [KO:K02183]
118664770  calmodulin-like protein 5 [KO:K02183]
118672571  LOW QUALITY PROTEIN: calmodulin-like protein 3 [KO:K02183]
118665863  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
118658714  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
118652970  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
118670159  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
118666917  RALGDS; ral guanine nucleotide dissociation stimulator isoform X1 [KO:K08732]
118660540  LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like [KO:K08732]
118665967  RALA; ras-related protein Ral-A [KO:K07834]
118661595  RALB; ras-related protein Ral-B [KO:K07835]
118663831  RALBP1; ralA-binding protein 1 isoform X1 [KO:K08773]
118675144  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
118657696  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
118651367  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
118671203  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
118675412  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
118671949  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
118657754  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
118652068  mitogen-activated protein kinase 9-like [KO:K04440] [EC:2.7.11.24]
118679322  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
118670993  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
118657540  PAX8; paired box protein Pax-8 isoform X1 [KO:K09293]
118668073  PPARG; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
118666894  RXRA; retinoic acid receptor RXR-alpha [KO:K08524]
118679517  RXRB; retinoic acid receptor RXR-beta isoform X1 [KO:K08525]
118673063  RXRG; retinoic acid receptor RXR-gamma isoform X1 [KO:K08526]
118668241  RARB; retinoic acid receptor beta isoform X1 [KO:K08528]
118660409  ESR1; estrogen receptor [KO:K08550]
118664766  ESR2; estrogen receptor beta [KO:K08551]
118669224  NCOA1; nuclear receptor coactivator 1 isoform X1 [KO:K09101] [EC:2.3.1.48]
118662730  NCOA3; nuclear receptor coactivator 3 isoform X1 [KO:K11256] [EC:2.3.1.48]
118650196  SP1; transcription factor Sp1 [KO:K04684]
118659942  PPARD; peroxisome proliferator-activated receptor delta isoform X1 [KO:K04504]
118671536  junction plakoglobin [KO:K10056]
118664314  ZBTB16; zinc finger and BTB domain-containing protein 16 isoform X1 [KO:K10055]
118671579  RARA; retinoic acid receptor alpha isoform X1 [KO:K08527]
118651324  CCNA1; cyclin-A1 isoform X1 [KO:K06627]
118658224  CCNA2; cyclin-A2 isoform X1 [KO:K06627]
118675706  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
118675205  RUNX1; runt-related transcription factor 1 isoform X1 [KO:K08367]
118670643  RUNX1T1; protein CBFA2T1 isoform X1 [KO:K10053]
118665067  SPI1; transcription factor PU.1 isoform X1 [KO:K09438]
118674315  CEBPA; CCAAT/enhancer-binding protein alpha [KO:K09055]
118657306  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like [KO:K05066]
118657314  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha [KO:K05066]
118676572  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
118657649  CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1 [KO:K05090] [EC:2.7.10.1]
118667589  cyclin-dependent kinase inhibitor 2A-like isoform X1 [KO:K06621]
118663841  E2F1; transcription factor E2F1 [KO:K17454]
118676426  E2F2; transcription factor E2F2 [KO:K09389]
118676306  E2F3; transcription factor E2F3 isoform X1 [KO:K06620]
118666425  protein max-like [KO:K04453]
118656510  MAX; protein max isoform X1 [KO:K04453]
118676019  ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 [KO:K10500]
118667590  CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685]
118666224  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
118650032  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
118660354  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
118674146  cyclin-dependent kinases regulatory subunit 2-like [KO:K02219]
118652523  CKS2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
118672784  CKS1B; cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
118659056  S-phase kinase-associated protein 1-like [KO:K03094]
118667519  S-phase kinase-associated protein 1-like [KO:K03094]
118669808  S-phase kinase-associated protein 1-like isoform X1 [KO:K03094]
118657630  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
118672352  S-phase kinase-associated protein 1-like [KO:K03094]
118666292  CUL1; cullin-1 isoform X1 [KO:K03347]
118677220  cullin-1-like [KO:K03347]
118650853  RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1 [KO:K03868] [EC:2.3.2.32]
118659026  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
118663966  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
118663967  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
118655860  SKP2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
118651193  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
118653038  CCNE1; G1/S-specific cyclin-E1 [KO:K06626]
118670629  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
118651068  RB1; retinoblastoma-associated protein isoform X1 [KO:K06618]
118658909  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
118652529  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma isoform X1 [KO:K04402]
118676452  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1 [KO:K04402]
118655437  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
118679638  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
118665064  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
118656304  POLK; DNA polymerase kappa isoform X1 [KO:K03511] [EC:2.7.7.7]
118656828  TERT; telomerase reverse transcriptase isoform X1 [KO:K11126] [EC:2.7.7.49]
118667895  MITF; microphthalmia-associated transcription factor isoform X1 [KO:K09455]
118674276  TGFB1; transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
118678846  TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
118658350  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
118667263  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
118668257  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
118662725  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
118654312  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
118662909  SMAD4; mothers against decapentaplegic homolog 4 [KO:K04501]
118676683  MECOM; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
118669630  CTBP2; C-terminal-binding protein 2 isoform X1 [KO:K04496] [EC:1.1.1.428]
118665242  CTBP1; C-terminal-binding protein 1 isoform X1 [KO:K04496] [EC:1.1.1.428]
118665982  LOW QUALITY PROTEIN: histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
118660079  HDAC2; histone deacetylase 2 isoform X1 [KO:K06067] [EC:3.5.1.98]
118676336  HDAC1; histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
118664991  histone deacetylase 2-like [KO:K06067] [EC:3.5.1.98]
118668289  MLH1; DNA mismatch repair protein Mlh1 [KO:K08734]
118669023  MSH2; DNA mismatch repair protein Msh2 isoform X1 [KO:K08735]
118656209  MSH3; DNA mismatch repair protein Msh3 [KO:K08736]
118669020  MSH6; DNA mismatch repair protein Msh6 isoform X1 [KO:K08737]
118651699  BRCA2; breast cancer type 2 susceptibility protein [KO:K08775]
118649936  RAD51; DNA repair protein RAD51 homolog 1 [KO:K04482]
118673639  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
118669989  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
118665178  FADD; FAS-associated death domain protein [KO:K02373]
118661495  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
118652071  BID; BH3-interacting domain death agonist isoform X1 [KO:K04726]
118663460  PMAIP1; LOW QUALITY PROTEIN: phorbol-12-myristate-13-acetate-induced protein 1 [KO:K10131]
118652805  BBC3; bcl-2-binding component 3 isoform X1 [KO:K10132]
118655230  BCL2L11; bcl-2-like protein 11 isoform X1 [KO:K16341]
118666111  cytochrome c [KO:K08738]
118679308  cytochrome c-like [KO:K08738]
118654943  cytochrome c-like [KO:K08738]
118650180  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
118669734  CASP7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
118658140  KEAP1; kelch-like ECH-associated protein 1 [KO:K10456]
118663270  LOW QUALITY PROTEIN: kelch-like ECH-associated protein 1 [KO:K10456]
118661195  NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638]
118650992  HMOX1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
118674375  NQO1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
118650895  MGST1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
118673065  MGST3; microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
118673257  GSTM3; glutathione S-transferase Mu 3 isoform X1 [KO:K00799] [EC:2.5.1.18]
118673261  glutathione S-transferase Mu 1 isoform X1 [KO:K00799] [EC:2.5.1.18]
118659150  MGST2; microsomal glutathione S-transferase 2 isoform X1 [KO:K00799] [EC:2.5.1.18]
118660224  glutathione S-transferase A4-like isoform X1 [KO:K00799] [EC:2.5.1.18]
118660225  glutathione S-transferase A4 isoform X1 [KO:K00799] [EC:2.5.1.18]
118660338  glutathione S-transferase A2-like isoform X1 [KO:K00799] [EC:2.5.1.18]
118660339  glutathione S-transferase A2 isoform X1 [KO:K00799] [EC:2.5.1.18]
118660483  glutathione S-transferase A2-like isoform X1 [KO:K00799] [EC:2.5.1.18]
118660484  glutathione S-transferase A1-like isoform X1 [KO:K00799] [EC:2.5.1.18]
118669765  GSTO1; glutathione S-transferase omega-1 [KO:K00799] [EC:2.5.1.18]
118669766  GSTO2; glutathione S-transferase omega-2 [KO:K00799] [EC:2.5.1.18]
118655504  glutathione S-transferase theta-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
118655505  glutathione S-transferase theta-2B-like [KO:K00799] [EC:2.5.1.18]
118655507  glutathione S-transferase theta-4-like [KO:K00799] [EC:2.5.1.18]
118655524  glutathione S-transferase theta-3-like [KO:K00799] [EC:2.5.1.18]
118665212  GSTP1; glutathione S-transferase P [KO:K23790] [EC:2.5.1.18]
118651685  TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X1 [KO:K22182] [EC:1.8.1.9]
118678102  TXNRD2; thioredoxin reductase 2, mitochondrial isoform X1 [KO:K22182] [EC:1.8.1.9]
118663161  TXNRD3; thioredoxin reductase 3 isoform X1 [KO:K22182] [EC:1.8.1.9]
118661708  elongin-C-like [KO:K03872]
118670947  ELOC; elongin-C [KO:K03872]
118656866  ELOB; elongin-B [KO:K03873]
118656714  cullin-2-like isoform X1 [KO:K03870]
118664716  LOW QUALITY PROTEIN: cullin-2-like [KO:K03870]
118676439  CUL2; cullin-2 isoform X1 [KO:K03870]
118678172  EGLN3; prolyl hydroxylase EGLN3 [KO:K09592] [EC:1.14.11.29]
118678818  EGLN1; egl nine homolog 1 isoform X1 [KO:K09592] [EC:1.14.11.29]
118674318  EGLN2; prolyl hydroxylase EGLN2 isoform X1 [KO:K09592] [EC:1.14.11.29]
118678831  FH; fumarate hydratase, mitochondrial [KO:K01679] [EC:4.2.1.2]
118656230  HIF1A; hypoxia-inducible factor 1-alpha isoform X1 [KO:K08268]
118669036  EPAS1; endothelial PAS domain-containing protein 1 isoform X1 [KO:K09095]
118672743  ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097]
118679109  ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1 [KO:K15589]
118651024  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
118656434  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
118675371  SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
118663641  JAG1; protein jagged-1 isoform X1 [KO:K06052]
118655026  JAG2; protein jagged-2 isoform X1 [KO:K21635]
118650012  DLL4; delta-like protein 4 [KO:K06051]
118674078  DLL3; delta-like protein 3 [KO:K06051]
118660373  DLL1; delta-like protein 1 isoform X1 [KO:K06051]
118655240  NOTCH1; neurogenic locus notch homolog protein 1 isoform X1 [KO:K02599]
118673433  NOTCH2; neurogenic locus notch homolog protein 2 isoform X1 [KO:K20994]
118652571  NOTCH3; neurogenic locus notch homolog protein 3 isoform X1 [KO:K20995]
118679629  NOTCH4; neurogenic locus notch homolog protein 4 [KO:K20996]
118676420  HES1; transcription factor HES-1 [KO:K06054]
118655604  HES5; transcription factor HES-5 [KO:K06055]
118660302  HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 [KO:K09091]
118671024  HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 [KO:K09091]
118677027  HEYL; hairy/enhancer-of-split related with YRPW motif-like protein isoform X1 [KO:K09091]
118658880  FLT4; vascular endothelial growth factor receptor 3 isoform X1 [KO:K05097] [EC:2.7.10.1]
118679449  SHH; sonic hedgehog protein [KO:K11988]
118667639  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
118666422  SMO; smoothened homolog isoform X1 [KO:K06226]
118679229  KIF7; kinesin-like protein KIF7 isoform X1 [KO:K18806]
118669796  SUFU; suppressor of fused homolog isoform X1 [KO:K06229]
118651345  GLI1; zinc finger protein GLI1 [KO:K16797]
118662026  GLI2; zinc finger protein GLI2 [KO:K16798]
118665962  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
118662859  BMP2; bone morphogenetic protein 2 isoform X1 [KO:K21283]
118655552  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
118658797  hedgehog-interacting protein isoform X1 [KO:K06231]
118676500  PTCH2; protein patched homolog 2 isoform X1 [KO:K11101]
118654148  AR; androgen receptor [KO:K08557]
118658235  heat shock protein HSP 90-beta [KO:K04079]
118666392  heat shock protein HSP 90-alpha-like [KO:K04079]
118659878  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
118659932  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
118654244  LOW QUALITY PROTEIN: heat shock protein HSP 90-beta-like [KO:K04079]
118650291  HSP90B1; endoplasmin isoform X1 [KO:K09487]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
Reference
  Authors
Weinberg RA.
  Title
The biology of cancer
  Journal
Garland Science, Taylor & Francis Group, LLC (2007)
Reference
PMID:10647931
  Authors
Hanahan D, Weinberg RA
  Title
The hallmarks of cancer.
  Journal
Cell 100:57-70 (2000)
DOI:10.1016/S0092-8674(00)81683-9
Reference
PMID:15000146
  Authors
Grady WM.
  Title
Genomic instability and colon cancer.
  Journal
Cancer Metastasis Rev 23:11-27 (2004)
DOI:10.1023/A:1025861527711
Reference
PMID:16555243
  Authors
Soreide K, Janssen EA, Soiland H, Korner H, Baak JP.
  Title
Microsatellite instability in colorectal cancer.
  Journal
Br J Surg 93:395-406 (2006)
DOI:10.1002/bjs.5328
Reference
PMID:11078609
  Authors
Anwar S, Hall C, White J, Deakin M, Farrell W, Elder JB.
  Title
Hereditary non-polyposis colorectal cancer: an updated review.
  Journal
Eur J Surg Oncol 26:635-45 (2000)
DOI:10.1053/ejso.2000.0974
Reference
PMID:16699851
  Authors
Takayama T, Miyanishi K, Hayashi T, Sato Y, Niitsu Y.
  Title
Colorectal cancer: genetics of development and metastasis.
  Journal
J Gastroenterol 41:185-92 (2006)
DOI:10.1007/s00535-006-1801-6
Reference
PMID:12621137
  Authors
Lynch HT, de la Chapelle A.
  Title
Hereditary colorectal cancer.
  Journal
N Engl J Med 348:919-32 (2003)
DOI:10.1056/NEJMra012242
Reference
PMID:12951588
  Authors
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C.
  Title
The significance of unstable chromosomes in colorectal cancer.
  Journal
Nat Rev Cancer 3:695-701 (2003)
DOI:10.1038/nrc1165
Reference
PMID:10505543
  Authors
Behrens J.
  Title
Cadherins and catenins: role in signal transduction and tumor progression.
  Journal
Cancer Metastasis Rev 18:15-30 (1999)
DOI:10.1023/A:1006200102166
Reference
PMID:16042571
  Authors
Behrens J.
  Title
The role of the Wnt signalling pathway in colorectal tumorigenesis.
  Journal
Biochem Soc Trans 33:672-5 (2005)
DOI:10.1042/BST0330672
Reference
PMID:15349822
  Authors
Behrens J, Lustig B.
  Title
The Wnt connection to tumorigenesis.
  Journal
Int J Dev Biol 48:477-87 (2004)
DOI:10.1387/ijdb.041815jb
Reference
PMID:9196022
  Authors
Polakis P.
  Title
The adenomatous polyposis coli (APC) tumor suppressor.
  Journal
Biochim Biophys Acta 1332:F127-47 (1997)
DOI:10.1016/S0304-419X(97)00008-5
Reference
PMID:12737309
  Authors
Janssen KP.
  Title
Murine models of colorectal cancer: studying the role of oncogenic K-ras.
  Journal
Cell Mol Life Sci 60:495-506 (2003)
DOI:10.1007/s000180300041
Reference
PMID:11459867
  Authors
Adjei AA.
  Title
Blocking oncogenic Ras signaling for cancer therapy.
  Journal
J Natl Cancer Inst 93:1062-74 (2001)
DOI:10.1093/jnci/93.14.1062
Reference
PMID:15573119
  Authors
Arakawa H.
  Title
Netrin-1 and its receptors in tumorigenesis.
  Journal
Nat Rev Cancer 4:978-87 (2004)
DOI:10.1038/nrc1504
Reference
PMID:15310786
  Authors
Mehlen P, Fearon ER.
  Title
Role of the dependence receptor DCC in colorectal cancer pathogenesis.
  Journal
J Clin Oncol 22:3420-8 (2004)
DOI:10.1200/JCO.2004.02.019
Reference
PMID:11223406
  Authors
Peltomaki P.
  Title
DNA mismatch repair and cancer.
  Journal
Mutat Res 488:77-85 (2001)
DOI:10.1016/S1383-5742(00)00058-2
Reference
PMID:15711891
  Authors
Li F, Cao Y, Townsend CM Jr, Ko TC.
  Title
TGF-beta signaling in colon cancer cells.
  Journal
World J Surg 29:306-11 (2005)
DOI:10.1007/s00268-004-7813-6
Reference
PMID:11170304
  Authors
Roman C, Saha D, Beauchamp R.
  Title
TGF-beta and colorectal carcinogenesis.
  Journal
Microsc Res Tech 52:450-7 (2001)
DOI:10.1002/1097-0029(20010215)52:4<450::AID-JEMT1030>3.0.CO;2-O
Reference
PMID:16326109
  Authors
Watson AJ.
  Title
An overview of apoptosis and the prevention of colorectal cancer.
  Journal
Crit Rev Oncol Hematol 57:107-21 (2006)
DOI:10.1016/j.critrevonc.2005.06.005
Reference
PMID:15479695
  Authors
Watson AJ.
  Title
Apoptosis and colorectal cancer.
  Journal
Gut 53:1701-9 (2004)
DOI:10.1136/gut.2004.052704
Reference
PMID:11477132
  Authors
Houlston RS.
  Title
What we could do now: molecular pathology of colorectal cancer.
  Journal
Mol Pathol 54:206-14 (2001)
DOI:10.1136/mp.54.4.206
Reference
  Authors
Von Hoff D, Evans D, Hruban R (ed).
  Title
Pancreatic cancer
  Journal
Jones and Bartlett publishers (2005)
Reference
  Authors
Niitsu Y, Yokota J (ed).
  Title
[Oncogenes and Tumor Suppressor Genes for Medical Oncologist] (In Japanese)
  Journal
Nankodo (1999)
Reference
PMID:12459728
  Authors
Bardeesy N, DePinho RA.
  Title
Pancreatic cancer biology and genetics.
  Journal
Nat Rev Cancer 2:897-909 (2002)
DOI:10.1038/nrc949
Reference
PMID:11407945
  Authors
Bardeesy N, Sharpless NE, DePinho RA, Merlino G.
  Title
The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.
  Journal
Semin Cancer Biol 11:201-18 (2001)
DOI:10.1006/scbi.2000.0371
Reference
PMID:12946833
  Authors
Cowgill SM, Muscarella P.
  Title
The genetics of pancreatic cancer.
  Journal
Am J Surg 186:279-86 (2003)
DOI:10.1016/S0002-9610(03)00226-5
Reference
PMID:16702400
  Authors
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA.
  Title
Genetics and biology of pancreatic ductal adenocarcinoma.
  Journal
Genes Dev 20:1218-49 (2006)
DOI:10.1101/gad.1415606
Reference
PMID:10740269
  Authors
Shields JM, Pruitt K, McFall A, Shaub A, Der CJ.
  Title
Understanding Ras: 'it ain't over 'til it's over'.
  Journal
Trends Cell Biol 10:147-54 (2000)
DOI:10.1016/S0962-8924(00)01740-2
Reference
PMID:12648469
  Authors
Holbro T, Civenni G, Hynes NE.
  Title
The ErbB receptors and their role in cancer progression.
  Journal
Exp Cell Res 284:99-110 (2003)
DOI:10.1016/S0014-4827(02)00099-X
Reference
PMID:14967450
  Authors
Marmor MD, Skaria KB, Yarden Y.
  Title
Signal transduction and oncogenesis by ErbB/HER receptors.
  Journal
Int J Radiat Oncol Biol Phys 58:903-13 (2004)
DOI:10.1016/j.ijrobp.2003.06.002
Reference
PMID:14586404
  Authors
DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW.
  Title
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
  Journal
Oncogene 22:7781-95 (2003)
DOI:10.1038/sj.onc.1206966
Reference
PMID:12545153
  Authors
Wei D, Le X, Zheng L, Wang L, Frey JA, Gao AC, Peng Z, Huang S, Xiong HQ, Abbruzzese JL, Xie K.
  Title
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
  Journal
Oncogene 22:319-29 (2003)
DOI:10.1038/sj.onc.1206122
Reference
PMID:14580692
  Authors
Toyonaga T, Nakano K, Nagano M, Zhao G, Yamaguchi K, Kuroki S, Eguchi T, Chijiiwa K, Tsuneyoshi M, Tanaka M.
  Title
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
  Journal
Cancer Lett 201:107-16 (2003)
DOI:10.1016/S0304-3835(03)00482-8
Reference
PMID:12079267
  Authors
Schmid RM.
  Title
Genetic basis of pancreatic cancer.
  Journal
Best Pract Res Clin Gastroenterol 16:421-33 (2002)
DOI:10.1053/bega.2002.0316
Reference
PMID:15774796
  Authors
Elliott RL, Blobe GC.
  Title
Role of transforming growth factor Beta in human cancer.
  Journal
J Clin Oncol 23:2078-93 (2005)
DOI:10.1200/JCO.2005.02.047
Reference
PMID:15823750
  Authors
Rudkin TM, Foulkes WD.
  Title
BRCA2: breaks, mistakes and failed separations.
  Journal
Trends Mol Med 11:145-8 (2005)
DOI:10.1016/j.molmed.2005.02.003
Reference
PMID:11707511
  Authors
Venkitaraman AR.
  Title
Functions of BRCA1 and BRCA2 in the biological response to DNA damage.
  Journal
J Cell Sci 114:3591-8 (2001)
Reference
PMID:15639402
  Authors
Soni D, King JA, Kaye AH, Hovens CM.
  Title
Genetics of glioblastoma multiforme: mitogenic signaling and cell cycle pathways converge.
  Journal
J Clin Neurosci 12:1-5 (2005)
DOI:10.1016/j.jocn.2004.04.001
Reference
PMID:12154354
  Authors
Zhu Y, Parada LF.
  Title
The molecular and genetic basis of neurological tumours.
  Journal
Nat Rev Cancer 2:616-26 (2002)
DOI:10.1038/nrc866
Reference
PMID:11253051
  Authors
Holland EC.
  Title
Gliomagenesis: genetic alterations and mouse models.
  Journal
Nat Rev Genet 2:120-9 (2001)
DOI:10.1038/35052535
Reference
PMID:16700615
  Authors
Bansal K, Liang ML, Rutka JT.
  Title
Molecular biology of human gliomas.
  Journal
Technol Cancer Res Treat 5:185-94 (2006)
DOI:10.1177/153303460600500302
Reference
  Authors
Tabuchi K (ed).
  Title
[Gliomas: Research and therapy] (In Japanese)
  Journal
Springer-Verlag Tokyo (2006)
Reference
PMID:12762887
  Authors
Kapoor GS, O'Rourke DM.
  Title
Mitogenic signaling cascades in glial tumors.
  Journal
Neurosurgery 52:1425-34; discussion 1434-5 (2003)
DOI:10.1227/01.NEU.0000065135.28143.39
Reference
PMID:16095998
  Authors
Hulleman E, Helin K.
  Title
Molecular mechanisms in gliomagenesis.
  Journal
Adv Cancer Res 94:1-27 (2005)
DOI:10.1016/S0065-230X(05)94001-3
Reference
PMID:11057895
  Authors
Schlessinger J.
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 103:211-25 (2000)
DOI:10.1016/S0092-8674(00)00114-8
Reference
PMID:9643506
  Authors
Ng HK, Lam PY.
  Title
The molecular genetics of central nervous system tumors.
  Journal
Pathology 30:196-202 (1998)
DOI:10.1080/00313029800169236
Reference
PMID:12084351
  Authors
Knobbe CB, Merlo A, Reifenberger G.
  Title
Pten signaling in gliomas.
  Journal
Neuro-oncol 4:196-211 (2002)
DOI:10.1093/neuonc/4.3.196
Reference
PMID:16557281
  Authors
Kondo T, Ezzat S, Asa SL.
  Title
Pathogenetic mechanisms in thyroid follicular-cell neoplasia.
  Journal
Nat Rev Cancer 6:292-306 (2006)
DOI:10.1038/nrc1836
Reference
PMID:16551846
  Authors
Chiloeches A, Marais R.
  Title
Is BRAF the Achilles' Heel of thyroid cancer?
  Journal
Clin Cancer Res 12:1661-4 (2006)
DOI:10.1158/1078-0432.CCR-06-0051
Reference
PMID:16946003
  Authors
Reddi HV, McIver B, Grebe SK, Eberhardt NL
  Title
The paired box-8/peroxisome proliferator-activated receptor-gamma oncogene in thyroid tumorigenesis.
  Journal
Endocrinology 148:932-5 (2007)
DOI:10.1210/en.2006-0926
Reference
PMID:17062879
  Authors
Santoro M, Melillo RM, Fusco A.
  Title
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture.
  Journal
Eur J Endocrinol 155:645-653 (2006)
DOI:10.1530/eje.1.02289
Reference
PMID:16242838
  Authors
Pierotti MA, Greco A.
  Title
Oncogenic rearrangements of the NTRK1/NGF receptor.
  Journal
Cancer Lett 232:90-8 (2006)
DOI:10.1016/j.canlet.2005.07.043
Reference
PMID:16189702
  Authors
Sobrinho-Simoes M, Preto A, Rocha AS, Castro P, Maximo V, Fonseca E, Soares P.
  Title
Molecular pathology of well-differentiated thyroid carcinomas.
  Journal
Virchows Arch 447:787-93 (2005)
DOI:10.1007/s00428-005-0065-5
Reference
PMID:11165748
  Authors
Gimm O.
  Title
Thyroid cancer.
  Journal
Cancer Lett 163:143-56 (2001)
DOI:10.1016/S0304-3835(00)00697-2
Reference
PMID:12094241
  Authors
Williams D.
  Title
Cancer after nuclear fallout: lessons from the Chernobyl accident.
  Journal
Nat Rev Cancer 2:543-9 (2002)
DOI:10.1038/nrc845
Reference
PMID:16236521
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
PMID:12563308
  Authors
Tenen DG.
  Title
Disruption of differentiation in human cancer: AML shows the way.
  Journal
Nat Rev Cancer 3:89-101 (2003)
DOI:10.1038/nrc989
Reference
PMID:16146838
  Authors
Choudhary C, Muller-Tidow C, Berdel WE, Serve H.
  Title
Signal transduction of oncogenic Flt3.
  Journal
Int J Hematol 82:93-9 (2005)
DOI:10.1532/IJH97.05090
Reference
PMID:12951584
  Authors
Stirewalt DL, Radich JP.
  Title
The role of FLT3 in haematopoietic malignancies.
  Journal
Nat Rev Cancer 3:650-65 (2003)
DOI:10.1038/nrc1169
Reference
PMID:16642045
  Authors
Martelli AM, Nyakern M, Tabellini G, Bortul R, Tazzari PL, Evangelisti C, Cocco L.
  Title
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
  Journal
Leukemia 20:911-28 (2006)
DOI:10.1038/sj.leu.2404245
Reference
PMID:15625120
  Authors
Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R.
  Title
Normal and oncogenic forms of the receptor tyrosine kinase kit.
  Journal
Stem Cells 23:16-43 (2005)
DOI:10.1634/stemcells.2004-0117
Reference
PMID:11721960
  Authors
Lorsbach RB, Downing JR.
  Title
The role of the AML1 transcription factor in leukemogenesis.
  Journal
Int J Hematol 74:258-65 (2001)
DOI:10.1007/BF02982058
Reference
PMID:12468433
  Authors
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Bohmer FD, Muller-Tidow C, Berdel WE, Serve H.
  Title
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
  Journal
Blood 101:3164-73 (2003)
DOI:10.1182/blood-2002-06-1677
Reference
PMID:17554387
  Authors
Mikesch JH, Steffen B, Berdel WE, Serve H, Muller-Tidow C.
  Title
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
  Journal
Leukemia 21:1638-47 (2007)
DOI:10.1038/sj.leu.2404732
Reference
PMID:16352814
  Authors
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG.
  Title
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.
  Journal
Blood 107:3330-8 (2006)
DOI:10.1182/blood-2005-07-3068
Reference
PMID:15719031
  Authors
Ren R.
  Title
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia.
  Journal
Nat Rev Cancer 5:172-83 (2005)
DOI:10.1038/nrc1567
Reference
PMID:11071626
  Authors
Deininger MW, Goldman JM, Melo JV.
  Title
The molecular biology of chronic myeloid leukemia.
  Journal
Blood 96:3343-56 (2000)
Reference
PMID:14982876
  Authors
Calabretta B, Perrotti D.
  Title
The biology of CML blast crisis.
  Journal
Blood 103:4010-22 (2004)
DOI:10.1182/blood-2003-12-4111
Reference
PMID:10403855
  Authors
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM.
  Title
The biology of chronic myeloid leukemia.
  Journal
N Engl J Med 341:164-72 (1999)
DOI:10.1056/NEJM199907153410306
Reference
PMID:15156182
  Authors
Mitani K.
  Title
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
  Journal
Oncogene 23:4263-9 (2004)
DOI:10.1038/sj.onc.1207777
Reference
PMID:16484590
  Authors
Dong M, Blobe GC.
  Title
Role of transforming growth factor-beta in hematologic malignancies.
  Journal
Blood 107:4589-96 (2006)
DOI:10.1182/blood-2005-10-4169
Reference
PMID:9834202
  Authors
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H.
  Title
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
  Journal
Blood 92:4003-12 (1998)
Reference
PMID:12801837
  Authors
Brusa G, Benvenuti M, Mazzacurati L, Mancini M, Pattacini L, Martinelli G, Barbieri E, Greenberger JS, Baccarani M, Santucci MA.
  Title
p53 loss of function enhances genomic instability and accelerates clonal evolution of murine myeloid progenitors expressing the p(210)BCR-ABL tyrosine kinase.
  Journal
Haematologica 88:622-30 (2003)
Reference
PMID:11160144
  Authors
Baldwin AS.
  Title
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.
  Journal
J Clin Invest 107:241-6 (2001)
DOI:10.1172/JCI11991
Reference
PMID:12244301
  Authors
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.
  Title
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
  Journal
Nat Med 8:1145-52 (2002)
DOI:10.1038/nm759
Reference
PMID:15948971
  Authors
Tilli CM, Van Steensel MA, Krekels GA, Neumann HA, Ramaekers FC.
  Title
Molecular aetiology and pathogenesis of basal cell carcinoma.
  Journal
Br J Dermatol 152:1108-24 (2005)
DOI:10.1111/j.1365-2133.2005.06587.x
Reference
PMID:12588368
  Authors
Saldanha G, Fletcher A, Slater DN.
  Title
Basal cell carcinoma: a dermatopathological and molecular biological update.
  Journal
Br J Dermatol 148:195-202 (2003)
DOI:10.1046/j.1365-2133.2003.05151.x
Reference
PMID:15978322
  Authors
Daya-Grosjean L, Couve-Privat S.
  Title
Sonic hedgehog signaling in basal cell carcinomas.
  Journal
Cancer Lett 225:181-92 (2005)
DOI:10.1016/j.canlet.2004.10.003
Reference
PMID:15468170
  Authors
Tsai KY, Tsao H.
  Title
The genetics of skin cancer.
  Journal
Am J Med Genet C Semin Med Genet 131C:82-92 (2004)
DOI:10.1002/ajmg.c.30037
Reference
PMID:16881963
  Authors
Athar M, Tang X, Lee JL, Kopelovich L, Kim AL.
  Title
Hedgehog signalling in skin development and cancer.
  Journal
Exp Dermatol 15:667-77 (2006)
DOI:10.1111/j.1600-0625.2006.00473.x
Reference
PMID:16306523
  Authors
Rubin AI, Chen EH, Ratner D.
  Title
Basal-cell carcinoma.
  Journal
N Engl J Med 353:2262-9 (2005)
DOI:10.1056/NEJMra044151
Reference
PMID:11276000
  Authors
Saldanha G.
  Title
The Hedgehog signalling pathway and cancer.
  Journal
J Pathol 193:427-32 (2001)
DOI:10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N
Reference
PMID:15270885
  Authors
Saldanha G, Ghura V, Potter L, Fletcher A.
  Title
Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation.
  Journal
Br J Dermatol 151:157-64 (2004)
DOI:10.1111/j.1365-2133.2004.06048.x
Reference
PMID:14737121
  Authors
Pasca di Magliano M, Hebrok M.
  Title
Hedgehog signalling in cancer formation and maintenance.
  Journal
Nat Rev Cancer 3:903-11 (2003)
DOI:10.1038/nrc1229
Reference
PMID:15656799
  Authors
Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G.
  Title
Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas.
  Journal
Br J Dermatol 152:43-51 (2005)
DOI:10.1111/j.1365-2133.2005.06353.x
Reference
PMID:14556242
  Authors
Cohen MM Jr.
  Title
The hedgehog signaling network.
  Journal
Am J Med Genet A 123:5-28 (2003)
DOI:10.1002/ajmg.a.20495
Reference
PMID:11736900
  Authors
Yamazaki F, Aragane Y, Kawada A, Tezuka T.
  Title
Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma.
  Journal
Br J Dermatol 145:771-7 (2001)
DOI:10.1046/j.1365-2133.2001.04468.x
Reference
PMID:16054233
  Authors
Erb P, Ji J, Wernli M, Kump E, Glaser A, Buchner SA.
  Title
Role of apoptosis in basal cell and squamous cell carcinoma formation.
  Journal
Immunol Lett 100:68-72 (2005)
DOI:10.1016/j.imlet.2005.06.008
Reference
PMID:11130178
  Authors
Toftgard R.
  Title
Hedgehog signalling in cancer.
  Journal
Cell Mol Life Sci 57:1720-31 (2000)
DOI:10.1007/PL00000654
Reference
PMID:16822996
  Authors
Miller AJ, Mihm MC Jr.
  Title
Melanoma.
  Journal
N Engl J Med 355:51-65 (2006)
DOI:10.1056/NEJMra052166
Reference
PMID:12894244
  Authors
Chin L.
  Title
The genetics of malignant melanoma: lessons from mouse and man.
  Journal
Nat Rev Cancer 3:559-70 (2003)
DOI:10.1038/nrc1145
Reference
PMID:16750612
  Authors
Takata M, Saida T.
  Title
Genetic alterations in melanocytic tumors.
  Journal
J Dermatol Sci 43:1-10 (2006)
DOI:10.1016/j.jdermsci.2006.05.002
Reference
PMID:15841168
  Authors
Chudnovsky Y, Khavari PA, Adams AE.
  Title
Melanoma genetics and the development of rational therapeutics.
  Journal
J Clin Invest 115:813-24 (2005)
DOI:10.1172/JCI24808
Reference
PMID:16001050
  Authors
Merlino G.
  Title
Cancer biology: the weakest link?
  Journal
Nature 436:33-5 (2005)
DOI:10.1038/436033a
Reference
PMID:16001072
  Authors
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR.
  Title
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
  Journal
Nature 436:117-22 (2005)
DOI:10.1038/nature03664
Reference
PMID:16899407
  Authors
Levy C, Khaled M, Fisher DE.
  Title
MITF: master regulator of melanocyte development and melanoma oncogene.
  Journal
Trends Mol Med 12:406-14 (2006)
DOI:10.1016/j.molmed.2006.07.008
Reference
PMID:15009714
  Authors
Tsao H, Goel V, Wu H, Yang G, Haluska FG.
  Title
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.
  Journal
J Invest Dermatol 122:337-41 (2004)
DOI:10.1046/j.0022-202X.2004.22243.x
Reference
PMID:11224709
  Authors
Gruss C, Herlyn M.
  Title
Role of cadherins and matrixins in melanoma.
  Journal
Curr Opin Oncol 13:117-23 (2001)
DOI:10.1097/00001622-200103000-00006
Reference
PMID:15721476
  Authors
Thompson JF, Scolyer RA, Kefford RF.
  Title
Cutaneous melanoma.
  Journal
Lancet 365:687-701 (2005)
DOI:10.1016/S0140-6736(05)17951-3
Reference
PMID:14695152
  Authors
Omholt K, Platz A, Kanter L, Ringborg U, Hansson J.
  Title
NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.
  Journal
Clin Cancer Res 9:6483-8 (2003)
Reference
PMID:15557758
  Authors
Hussein MR.
  Title
The TP53 tumor suppressor gene and melanoma tumorigenesis: is there a relationship?
  Journal
Tumour Biol 25:200-7 (2004)
DOI:10.1159/000081103
Reference
PMID:10843728
  Authors
Lazar-Molnar E, Hegyesi H, Toth S, Falus A.
  Title
Autocrine and paracrine regulation by cytokines and growth factors in melanoma.
  Journal
Cytokine 12:547-54 (2000)
DOI:10.1006/cyto.1999.0614
Reference
PMID:16339096
  Authors
Cohen HT, McGovern FJ.
  Title
Renal-cell carcinoma.
  Journal
N Engl J Med 353:2477-90 (2005)
DOI:10.1056/NEJMra043172
Reference
PMID:15122209
  Authors
Pavlovich CP, Schmidt LS.
  Title
Searching for the hereditary causes of renal-cell carcinoma.
  Journal
Nat Rev Cancer 4:381-93 (2004)
DOI:10.1038/nrc1364
Reference
PMID:14634372
  Authors
Linehan WM, Walther MM, Zbar B.
  Title
The genetic basis of cancer of the kidney.
  Journal
J Urol 170:2163-72 (2003)
DOI:10.1097/01.ju.0000096060.92397.ed
Reference
PMID:14685170
  Authors
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF.
  Title
Met, metastasis, motility and more.
  Journal
Nat Rev Mol Cell Biol 4:915-25 (2003)
DOI:10.1038/nrm1261
Reference
PMID:15611513
  Authors
Kim WY, Kaelin WG.
  Title
Role of VHL gene mutation in human cancer.
  Journal
J Clin Oncol 22:4991-5004 (2004)
DOI:10.1200/JCO.2004.05.061
Reference
PMID:17211469
  Authors
Sudarshan S, Linehan WM, Neckers L.
  Title
HIF and fumarate hydratase in renal cancer.
  Journal
Br J Cancer 96:403-7 (2007)
DOI:10.1038/sj.bjc.6603547
Reference
PMID:17287871
  Authors
Sudarshan S, Pinto PA, Neckers L, Linehan WM.
  Title
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer.
  Journal
Nat Clin Pract Urol 4:104-10 (2007)
DOI:10.1038/ncpuro0711
Reference
PMID:12351585
  Authors
Bodmer D, van den Hurk W, van Groningen JJ, Eleveld MJ, Martens GJ, Weterman MA, van Kessel AG.
  Title
Understanding familial and non-familial renal cell cancer.
  Journal
Hum Mol Genet 11:2489-98 (2002)
DOI:10.1093/hmg/11.20.2489
Reference
PMID:17158541
  Authors
Mitra AP, Datar RH, Cote RJ.
  Title
Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification.
  Journal
J Clin Oncol 24:5552-64 (2006)
DOI:10.1200/JCO.2006.08.2073
Reference
PMID:16474624
  Authors
Wolff EM, Liang G, Jones PA.
  Title
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer.
  Journal
Nat Clin Pract Urol 2:502-10 (2005)
DOI:10.1038/ncpuro0318
Reference
PMID:16110317
  Authors
Wu XR.
  Title
Urothelial tumorigenesis: a tale of divergent pathways.
  Journal
Nat Rev Cancer 5:713-25 (2005)
DOI:10.1038/nrc1697
Reference
PMID:11103787
  Authors
Brown NS, Jones A, Fujiyama C, Harris AL, Bicknell R.
  Title
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
  Journal
Cancer Res 60:6298-302 (2000)
Reference
PMID:12850530
  Authors
Bellmunt J, Hussain M, Dinney CP.
  Title
Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family.
  Journal
Crit Rev Oncol Hematol 46 Suppl:S85-104 (2003)
DOI:10.1016/S1040-8428(03)00067-2
Reference
PMID:17149381
  Authors
Sugano K, Kakizoe T.
  Title
Genetic alterations in bladder cancer and their clinical applications in molecular tumor staging.
  Journal
Nat Clin Pract Urol 3:642-52 (2006)
DOI:10.1038/ncpuro0649
Reference
PMID:15746962
  Authors
Dunn KL, Espino PS, Drobic B, He S, Davie JR.
  Title
The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.
  Journal
Biochem Cell Biol 83:1-14 (2005)
DOI:10.1139/o04-121
Reference
PMID:15551095
  Authors
Williams SG, Stein JP.
  Title
Molecular pathways in bladder cancer.
  Journal
Urol Res 32:373-85 (2004)
DOI:10.1007/s00240-003-0345-y
Reference
PMID:12878745
  Authors
Nelson WG, De Marzo AM, Isaacs WB.
  Title
Prostate cancer.
  Journal
N Engl J Med 349:366-81 (2003)
DOI:10.1056/NEJMra021562
Reference
PMID:15724144
  Authors
Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC.
  Title
The emerging role of the PI3-K-Akt pathway in prostate cancer progression.
  Journal
Prostate Cancer Prostatic Dis 8:108-18 (2005)
DOI:10.1038/sj.pcan.4500776
Reference
PMID:16551847
  Authors
Pienta KJ, Bradley D.
  Title
Mechanisms underlying the development of androgen-independent prostate cancer.
  Journal
Clin Cancer Res 12:1665-71 (2006)
DOI:10.1158/1078-0432.CCR-06-0067
Reference
PMID:11900250
  Authors
Feldman BJ, Feldman D.
  Title
The development of androgen-independent prostate cancer.
  Journal
Nat Rev Cancer 1:34-45 (2001)
DOI:10.1038/35094009
Reference
PMID:15082523
  Authors
Heinlein CA, Chang C.
  Title
Androgen receptor in prostate cancer.
  Journal
Endocr Rev 25:276-308 (2004)
DOI:10.1210/er.2002-0032
Reference
PMID:9422516
  Authors
Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP.
  Title
Androgen receptor gene and hormonal therapy failure of prostate cancer.
  Journal
Am J Pathol 152:1-9 (1998)
Reference
PMID:10835690
  Authors
Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, Feldman D.
  Title
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor.
  Journal
Nat Med 6:703-6 (2000)
DOI:10.1038/76287
Reference
PMID:10453277
  Authors
Macri E, Loda M.
  Title
Role of p27 in prostate carcinogenesis.
  Journal
Cancer Metastasis Rev 17:337-44 (1998)
DOI:10.1023/A:1006133620914
Reference
PMID:11750244
  Authors
Steers WD.
  Title
5alpha-reductase activity in the prostate.
  Journal
Urology 58:17-24; discussion 24 (2001)
DOI:10.1016/S0090-4295(01)01299-7
Reference
PMID:8069858
  Authors
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF.
  Title
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
  Journal
Cancer Res 54:4920-6 (1994)
Reference
PMID:11527574
  Authors
Grimes CA, Jope RS.
  Title
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
  Journal
Prog Neurobiol 65:391-426 (2001)
DOI:10.1016/S0301-0082(01)00011-9
Reference
PMID:15947972
  Authors
Ryan AJ, Susil B, Jobling TW, Oehler MK.
  Title
Endometrial cancer.
  Journal
Cell Tissue Res 322:53-61 (2005)
DOI:10.1007/s00441-005-1109-5
Reference
PMID:14747944
  Authors
Lax SF.
  Title
Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification.
  Journal
Virchows Arch 444:213-23 (2004)
DOI:10.1007/s00428-003-0947-3
Reference
PMID:16508724
  Authors
Shiozawa T, Konishi I.
  Title
Early endometrial carcinoma: clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment.
  Journal
Int J Clin Oncol 11:13-21 (2006)
DOI:10.1007/s10147-005-0546-1
Reference
PMID:17028294
  Authors
Hecht JL, Mutter GL.
  Title
Molecular and pathologic aspects of endometrial carcinogenesis.
  Journal
J Clin Oncol 24:4783-91 (2006)
DOI:10.1200/JCO.2006.06.7173
Reference
PMID:11431710
  Authors
Matias-Guiu X, Catasus L, Bussaglia E, Lagarda H, Garcia A, Pons C, Munoz J, Arguelles R, Machin P, Prat J.
  Title
Molecular pathology of endometrial hyperplasia and carcinoma.
  Journal
Hum Pathol 32:569-77 (2001)
DOI:10.1053/hupa.2001.25929
Reference
PMID:15284264
  Authors
Slomovitz BM, Broaddus RR, Burke TW, Sneige N, Soliman PT, Wu W, Sun CC, Munsell MF, Gershenson DM, Lu KH.
  Title
Her-2/neu overexpression and amplification in uterine papillary serous carcinoma.
  Journal
J Clin Oncol 22:3126-32 (2004)
DOI:10.1200/JCO.2004.11.154
Reference
PMID:7585656
  Authors
Saffari B, Jones LA, el-Naggar A, Felix JC, George J, Press MF.
  Title
Amplification and overexpression of HER-2/neu (c-erbB2) in endometrial cancers: correlation with overall survival.
  Journal
Cancer Res 55:5693-8 (1995)
Reference
PMID:16248975
  Authors
Kim D, Chung J.
  Title
Akt: versatile mediator of cell survival and beyond.
  Journal
J Biochem Mol Biol 35:106-15 (2002)
DOI:10.5483/bmbrep.2002.35.1.106
Reference
PMID:12711111
  Authors
Sanchez-Cespedes M.
  Title
Dissecting the genetic alterations involved in lung carcinogenesis.
  Journal
Lung Cancer 40:111-21 (2003)
DOI:10.1016/S0169-5002(03)00033-3
Reference
PMID:11720739
  Authors
Kaye FJ.
  Title
Molecular biology of lung cancer.
  Journal
Lung Cancer 34 Suppl 2:S35-41 (2001)
DOI:10.1016/S0169-5002(01)00342-7
Reference
PMID:12616528
  Authors
Shivapurkar N, Reddy J, Chaudhary PM, Gazdar AF.
  Title
Apoptosis and lung cancer: a review.
  Journal
J Cell Biochem 88:885-98 (2003)
DOI:10.1002/jcb.10440
Reference
PMID:11807782
  Authors
Sartorius UA, Krammer PH.
  Title
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
  Journal
Int J Cancer 97:584-92 (2002)
DOI:10.1002/ijc.10096
Reference
PMID:16064138
  Authors
Adhikary S, Eilers M.
  Title
Transcriptional regulation and transformation by Myc proteins.
  Journal
Nat Rev Mol Cell Biol 6:635-45 (2005)
DOI:10.1038/nrm1703
Reference
PMID:11463388
  Authors
Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI.
  Title
A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
  Journal
Mol Cell 7:639-50 (2001)
DOI:10.1016/S1097-2765(01)00210-6
Reference
PMID:15109562
  Authors
Buttery RC, Rintoul RC, Sethi T.
  Title
Small cell lung cancer: the importance of the extracellular matrix.
  Journal
Int J Biochem Cell Biol 36:1154-60 (2004)
DOI:10.1016/S1357-2725(03)00261-9
Reference
PMID:11559746
  Authors
Yamada KM, Araki M.
  Title
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis.
  Journal
J Cell Sci 114:2375-82 (2001)
Reference
PMID:11905738
  Authors
Rintoul RC, Sethi T.
  Title
The role of extracellular matrix in small-cell lung cancer.
  Journal
Lancet Oncol 2:437-42 (2001)
DOI:10.1016/S1470-2045(00)00421-6
Reference
PMID:12243753
  Authors
Ekedahl J, Joseph B, Grigoriev MY, Muller M, Magnusson C, Lewensohn R, Zhivotovsky B.
  Title
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.
  Journal
Exp Cell Res 279:277-90 (2002)
DOI:10.1006/excr.2002.5608
Reference
PMID:12379883
  Authors
Osada H, Takahashi T.
  Title
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.
  Journal
Oncogene 21:7421-34 (2002)
DOI:10.1038/sj.onc.1205802
Reference
PMID:12741677
  Authors
Yokota J, Nishioka M, Tani M, Kohno T.
  Title
Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
  Journal
Clin Exp Metastasis 20:189-93 (2003)
DOI:10.1023/a:1022978932215
Reference
PMID:16870043
  Authors
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS.
  Title
K-ras mutations in non-small-cell lung carcinoma: a review.
  Journal
Clin Lung Cancer 8:30-8 (2006)
DOI:10.3816/CLC.2006.n.030
Reference
PMID:15948711
  Authors
Pfeifer GP, Dammann R.
  Title
Methylation of the tumor suppressor gene RASSF1A in human tumors.
  Journal
Biochemistry (Mosc) 70:576-83 (2005)
DOI:10.1007/s10541-005-0151-y
Reference
PMID:11902573
  Authors
Altucci L, Gronemeyer H.
  Title
The promise of retinoids to fight against cancer.
  Journal
Nat Rev Cancer 1:181-93 (2001)
DOI:10.1038/35106036
Reference
PMID:10944551
  Authors
Virmani AK, Rathi A, Zochbauer-Muller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF.
  Title
Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.
  Journal
J Natl Cancer Inst 92:1303-7 (2000)
DOI:10.1093/jnci/92.16.1303
Reference
PMID:12867060
  Authors
Hirsch FR, Scagliotti GV, Langer CJ, Varella-Garcia M, Franklin WA.
  Title
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies.
  Journal
Lung Cancer 41 Suppl 1:S29-42 (2003)
DOI:10.1016/S0169-5002(03)00137-5
Reference
PMID:16112428
  Authors
Panani AD, Roussos C.
  Title
Cytogenetic and molecular aspects of lung cancer.
  Journal
Cancer Lett 239:1-9 (2006)
DOI:10.1016/j.canlet.2005.06.030
Reference
PMID:12407699
  Authors
Mitsuuchi Y, Testa JR.
  Title
Cytogenetics and molecular genetics of lung cancer.
  Journal
Am J Med Genet 115:183-8 (2002)
DOI:10.1002/ajmg.10692
Reference
PMID:15942304
  Authors
Breuer RH, Postmus PE, Smit EF.
  Title
Molecular pathology of non-small-cell lung cancer.
  Journal
Respiration 72:313-30 (2005)
DOI:10.1159/000085376
Reference
PMID:11895903
  Authors
Piyathilake CJ, Frost AR, Manne U, Weiss H, Bell WC, Heimburger DC, Grizzle WE.
  Title
Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.
  Journal
Clin Cancer Res 8:734-44 (2002)
Reference
PMID:16189154
  Authors
Awaya H, Takeshima Y, Furonaka O, Kohno N, Inai K.
  Title
Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung.
  Journal
J Clin Pathol 58:1076-80 (2005)
DOI:10.1136/jcp.2004.025585
Reference
PMID:21193867
  Authors
Lappano R, Maggiolini M
  Title
G protein-coupled receptors: novel targets for drug discovery in cancer.
  Journal
Nat Rev Drug Discov 10:47-60 (2011)
DOI:10.1038/nrd3320
Reference
PMID:24508914
  Authors
O'Hayre M, Degese MS, Gutkind JS
  Title
Novel insights into G protein and G protein-coupled receptor signaling in cancer.
  Journal
Curr Opin Cell Biol 27:126-35 (2014)
DOI:10.1016/j.ceb.2014.01.005
Reference
PMID:17251915
  Authors
Dorsam RT, Gutkind JS
  Title
G-protein-coupled receptors and cancer.
  Journal
Nat Rev Cancer 7:79-94 (2007)
DOI:10.1038/nrc2069
Related
pathway
mmyo03320  PPAR signaling pathway
mmyo04010  MAPK signaling pathway
mmyo04020  Calcium signaling pathway
mmyo04024  cAMP signaling pathway
mmyo04060  Cytokine-cytokine receptor interaction
mmyo04066  HIF-1 signaling pathway
mmyo04110  Cell cycle
mmyo04115  p53 signaling pathway
mmyo04150  mTOR signaling pathway
mmyo04151  PI3K-Akt signaling pathway
mmyo04210  Apoptosis
mmyo04310  Wnt signaling pathway
mmyo04330  Notch signaling pathway
mmyo04340  Hedgehog signaling pathway
mmyo04350  TGF-beta signaling pathway
mmyo04370  VEGF signaling pathway
mmyo04510  Focal adhesion
mmyo04512  ECM-receptor interaction
mmyo04520  Adherens junction
mmyo04630  JAK-STAT signaling pathway
mmyo04915  Estrogen signaling pathway
KO pathway
ko05200   
LinkDB

DBGET integrated database retrieval system