KEGG   PATHWAY: hsa00052
Entry
hsa00052                    Pathway                                
Name
Galactose metabolism - Homo sapiens (human)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hsa00052  Galactose metabolism
hsa00052

Module
hsa_M00554  Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:hsa00052]
hsa_M00632  Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:hsa00052]
Network
  Element
N00847  Galactose degradation
Drug
D00216  Acarbose (JAN/USAN/INN)
D00625  Miglitol (JP18/USAN/INN)
D01665  Voglibose (JP18/USAN/INN)
D01688  Epalrestat (JP18/INN)
D01715  Risarestat (INN)
D01842  Fidarestat (JAN/INN)
D02323  Tolrestat (USAN/INN)
D02328  Zopolrestat (USAN/INN)
D02835  Alrestatin sodium (USAN)
D03207  Alglucosidase alfa (USAN/INN)
D03342  Camiglibose (USAN)
D03803  Lidorestat (USAN)
D03805  Minalrestat (USAN/INN)
D03806  Ponalrestat (USAN/INN)
D03807  Zenarestat (USAN/INN)
D05893  Sorbinil (USAN/INN)
D06403  Ranirestat (JAN/INN)
D09605  Duvoglustat (USAN/INN)
D09606  Duvoglustat hydrochloride (USAN)
D09779  Emiglitate (JAN/INN)
D11744  Avalglucosidase alfa (USAN/INN)
D11798  Cipaglucosidase alfa (USAN)
D11828  Clervonafusp alfa (USAN/INN)
D12384  Govorestat (USAN/INN)
D12390  Caficrestat (USAN/INN)
Other DBs
GO: 0006012
Organism
Homo sapiens (human) [GN:hsa]
Gene
130589  GALM; galactose mutarotase [KO:K01785] [EC:5.1.3.3]
2584  GALK1; galactokinase 1 [KO:K00849] [EC:2.7.1.6]
2592  GALT; galactose-1-phosphate uridylyltransferase [KO:K00965] [EC:2.7.7.12]
2582  GALE; UDP-galactose-4-epimerase [KO:K01784] [EC:5.1.3.2]
7360  UGP2; UDP-glucose pyrophosphorylase 2 [KO:K00963] [EC:2.7.7.9]
5236  PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
55276  PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
3101  HK3; hexokinase 3 [KO:K00844] [EC:2.7.1.1]
3098  HK1; hexokinase 1 [KO:K00844] [EC:2.7.1.1]
3099  HK2; hexokinase 2 [KO:K00844] [EC:2.7.1.1]
80201  HKDC1; hexokinase domain containing 1 [KO:K00844] [EC:2.7.1.1]
2645  GCK; glucokinase [KO:K12407] [EC:2.7.1.2]
2538  G6PC1; glucose-6-phosphatase catalytic subunit 1 [KO:K01084] [EC:3.1.3.9]
57818  G6PC2; glucose-6-phosphatase catalytic subunit 2 [KO:K01084] [EC:3.1.3.9]
92579  G6PC3; glucose-6-phosphatase catalytic subunit 3 [KO:K01084] [EC:3.1.3.9]
2720  GLB1; galactosidase beta 1 [KO:K12309] [EC:3.2.1.23]
3938  LCT; lactase [KO:K01229] [EC:3.2.1.108 3.2.1.62]
3906  LALBA; lactalbumin alpha [KO:K00704] [EC:2.4.1.22]
2683  B4GALT1; beta-1,4-galactosyltransferase 1 [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
8704  B4GALT2; beta-1,4-galactosyltransferase 2 [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
2717  GLA; galactosidase alpha [KO:K01189] [EC:3.2.1.22]
231  AKR1B1; aldo-keto reductase family 1 member B [KO:K00011] [EC:1.1.1.21]
57016  AKR1B10; aldo-keto reductase family 1 member B10 [KO:K00011] [EC:1.1.1.21]
441282  AKR1B15; aldo-keto reductase family 1 member B15 [KO:K00011] [EC:1.1.1.21]
5213  PFKM; phosphofructokinase, muscle [KO:K00850] [EC:2.7.1.11]
5214  PFKP; phosphofructokinase, platelet [KO:K00850] [EC:2.7.1.11]
5211  PFKL; phosphofructokinase, liver type [KO:K00850] [EC:2.7.1.11]
8972  MGAM; maltase-glucoamylase [KO:K12047] [EC:3.2.1.20 3.2.1.3]
93432  MGAM2; maltase-glucoamylase 2 (putative) [KO:K12047] [EC:3.2.1.20 3.2.1.3]
2548  GAA; alpha glucosidase [KO:K12316] [EC:3.2.1.20]
2595  GANC; glucosidase alpha, neutral C [KO:K12317] [EC:3.2.1.20]
6476  SI; sucrase-isomaltase [KO:K01203] [EC:3.2.1.48 3.2.1.10]
Compound
C00029  UDP-glucose
C00031  D-Glucose
C00052  UDP-alpha-D-galactose
C00085  D-Fructose 6-phosphate
C00089  Sucrose
C00095  D-Fructose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00118  D-Glyceraldehyde 3-phosphate
C00124  D-Galactose
C00137  myo-Inositol
C00159  D-Mannose
C00243  Lactose
C00267  alpha-D-Glucose
C00446  alpha-D-Galactose 1-phosphate
C00492  Raffinose
C00577  D-Glyceraldehyde
C00668  alpha-D-Glucose 6-phosphate
C00794  D-Sorbitol
C00795  D-Tagatose
C00880  D-Galactonate
C00984  alpha-D-Galactose
C01097  D-Tagatose 6-phosphate
C01113  D-Galactose 6-phosphate
C01132  N-Acetyl-D-galactosamine
C01216  2-Dehydro-3-deoxy-D-galactonate
C01235  alpha-D-Galactosyl-(1->3)-1D-myo-inositol
C01286  2-Dehydro-3-deoxy-6-phospho-D-galactonate
C01613  Stachyose
C01697  Galactitol
C02262  D-Galactosamine
C02669  D-Galactono-1,5-lactone
C03383  D-Galactono-1,4-lactone
C03733  UDP-alpha-D-galactofuranose
C03785  D-Tagatose 1,6-bisphosphate
C05396  Lactose 6'-phosphate
C05399  Melibiitol
C05400  Epimelibiose
C05401  3-beta-D-Galactosyl-sn-glycerol
C05402  Melibiose
C05404  D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose
C05796  Galactan
C06311  Galactitol 1-phosphate
C06376  N-Acetyl-D-galactosamine 6-phosphate
C06377  D-Galactosamine 6-phosphate
Related
pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00030  Pentose phosphate pathway
hsa00040  Pentose and glucuronate interconversions
hsa00051  Fructose and mannose metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
KO pathway
ko00052   
LinkDB

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