KEGG   PATHWAY: lroh04070
Entry
lroh04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Labeo rohita (rohu)
Class
Environmental Information Processing; Signal transduction
Pathway map
lroh04070  Phosphatidylinositol signaling system
lroh04070

Organism
Labeo rohita (rohu) [GN:lroh]
Gene
127171976  pi4kaa; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
127178482  pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
127165356  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
127167813  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
127181867  sacm1la; phosphatidylinositol-3-phosphatase SAC1-A [KO:K21797] [EC:3.1.3.-]
127178540  sacm1lb; phosphatidylinositol-3-phosphatase SAC1-B [KO:K21797] [EC:3.1.3.-]
127175301  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
127169818  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
127181997  pip5k1aa; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a isoform X1 [KO:K00889] [EC:2.7.1.68]
127154013  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
127172275  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a isoform X1 [KO:K00889] [EC:2.7.1.68]
127178390  pip5k1ab; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
127178528  pip5k1cb; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b isoform X1 [KO:K00889] [EC:2.7.1.68]
127175918  ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
127178451  inpp5b; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase [KO:K01099] [EC:3.1.3.36]
127166138  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
127172491  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
127154480  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
127177108  pik3cb; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
127172737  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
127162255  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
127176088  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
127164849  pik3r1; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
127166520  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
127179724  ptena; phosphatase and tensin homolog A isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
127174135  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
127166754  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
127176330  inppl1b; inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
127177620  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A isoform X1 [KO:K15909] [EC:3.1.3.86]
127163761  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
127167367  inpp4ab; inositol polyphosphate-4-phosphatase type I Ab isoform X1 [KO:K01109] [EC:3.1.3.66]
127170827  inpp4aa; LOW QUALITY PROTEIN: inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
127170850  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
127167830  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
127166057  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
127167827  mtmr1a; myotubularin-related protein 1a isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
127152677  mtmr1b; myotubularin-related protein 1b isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
127170115  mtmr3; LOW QUALITY PROTEIN: myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
127165447  myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
127165486  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
127176054  mtmr7a; myotubularin-related protein 7a [KO:K18083] [EC:3.1.3.64 3.1.3.95]
127156006  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
127165912  mtmr8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
127156285  mtmr7b; myotubularin-related protein 7b isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
127166731  mtmr14; LOW QUALITY PROTEIN: myotubularin-related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
127154758  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
127155704  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
127161287  pip4k2cb; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
127180668  pip4k2ab; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
127169912  pip4p1b; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-B [KO:K13084] [EC:3.1.3.78]
127182155  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
127177288  pip4p1a; type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A [KO:K13084] [EC:3.1.3.78]
127168571  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
127173073  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
127180757  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
127181223  pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
127179467  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
127179468  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
127168134  plcb3; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
127179936  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
127182802  plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
127182984  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
127153583  plcd1b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1b isoform X1 [KO:K05857] [EC:3.1.4.11]
127170560  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
127155634  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
127157439  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
127174340  plcd3b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
127153175  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
127173956  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
127154337  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
127181164  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
127174195  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
127174919  ipmka; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
127179455  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
127180727  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
127152769  itpkca; LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
127182986  itpkb; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
127179950  itpk1b; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
127182890  itpk1a; LOW QUALITY PROTEIN: inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
127153215  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
127153703  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
127166848  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
127166900  ip6k2a; inositol hexakisphosphate kinase 2a [KO:K07756] [EC:2.7.4.21]
127171840  ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
127156376  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
127168355  ppip5k1a; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
127161315  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
127156119  impa2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
127172968  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
127160818  bpnt2; inositol monophosphatase 3 isoform X1 [KO:K15759] [EC:3.1.3.7]
127176007  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
127163940  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
127170584  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
127170589  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
127154761  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
127177137  diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
127177722  dgkb; LOW QUALITY PROTEIN: diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
127156380  dgkzb; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
127166532  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
127161284  dgkab; diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
127168506  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
127168865  dgkza; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
127165156  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
127165274  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
127163465  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
127172757  itpr1b; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
127166842  itpr1a; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
127180437  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
127169168  itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
127166764  prkcaa; LOW QUALITY PROTEIN: protein kinase C, alpha, a [KO:K02677] [EC:2.7.11.13]
127163386  prkcab; LOW QUALITY PROTEIN: protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
127160219  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
127163312  prkcba; protein kinase C, beta a isoform X1 [KO:K19662] [EC:2.7.11.13]
127178761  prkcg; protein kinase C alpha type [KO:K19663] [EC:2.7.11.13]
127177273  calm3a; calmodulin 3a (phosphorylase kinase, delta) isoform X1 [KO:K02183]
127157137  calml4b; calmodulin-like protein 4 [KO:K02183]
127173904  calm2b; calmodulin 2b, (phosphorylase kinase, delta) [KO:K02183]
127179643  calm1a; calmodulin-1a [KO:K02183]
127152231  calm3b; calmodulin 3b (phosphorylase kinase, delta) [KO:K02183]
127168935  calml4a; calmodulin-like protein 4a [KO:K02183]
127175157  calm2a; calmodulin 2a (phosphorylase kinase, delta) [KO:K02183]
127182897  calm1b; calmodulin-1b [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
lroh04020  Calcium signaling pathway
lroh04144  Endocytosis
lroh04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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