KEGG   PATHWAY: aplc00230
Entry
aplc00230                   Pathway                                
Name
Purine metabolism - Acanthaster planci (crown-of-thorns starfish)
Class
Metabolism; Nucleotide metabolism
Pathway map
aplc00230  Purine metabolism
aplc00230

Module
aplc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:aplc00230]
aplc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:aplc00230]
aplc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aplc00230]
aplc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aplc00230]
aplc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aplc00230]
aplc_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:aplc00230]
aplc_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:aplc00230]
Other DBs
GO: 0006163 0042278
Organism
Acanthaster planci (crown-of-thorns starfish) [GN:aplc]
Gene
110984842  ADP-ribose pyrophosphatase, mitochondrial-like [KO:K13988] [EC:3.6.1.13]
110989831  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
110978621  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
110987738  ADP-sugar pyrophosphatase-like [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
110989373  phosphoglucomutase-1-like [KO:K01835] [EC:5.4.2.2]
110979809  glucose 1,6-bisphosphate synthase-like isoform X1 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
110988634  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
110988625  amidophosphoribosyltransferase-like isoform X1 [KO:K00764] [EC:2.4.2.14]
110974915  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
110989801  phosphoribosylformylglycinamidine synthase-like isoform X1 [KO:K01952] [EC:6.3.5.3]
110988626  multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
110980289  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
110974587  bifunctional purine biosynthesis protein PURH-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
110980126  LOW QUALITY PROTEIN: adenine phosphoribosyltransferase-like [KO:K00759] [EC:2.4.2.7]
110988384  uncharacterized protein LOC110988384 [KO:K01081] [EC:3.1.3.5]
110983072  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
110987844  5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
110984626  5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
110983303  5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
110984761  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
110973469  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
110988869  inosine-5'-monophosphate dehydrogenase 2-like isoform X1 [KO:K00088] [EC:1.1.1.205]
110977958  nucleoside diphosphate kinase 7-like [KO:K00940] [EC:2.7.4.6]
110976854  nucleoside diphosphate kinase A1-like [KO:K00940] [EC:2.7.4.6]
110978783  nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
110981474  adenylate kinase 9-like isoform X1 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
110973950  ectonucleoside triphosphate diphosphohydrolase 1-like [KO:K01510] [EC:3.6.1.5]
110973952  ectonucleoside triphosphate diphosphohydrolase 8-like isoform X1 [KO:K01510] [EC:3.6.1.5]
110983083  ectonucleoside triphosphate diphosphohydrolase 2-like [KO:K01510] [EC:3.6.1.5]
110976233  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
110979908  ectonucleoside triphosphate diphosphohydrolase 4-like isoform X1 [KO:K12305] [EC:3.6.1.6]
110981511  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
110975833  inosine triphosphate pyrophosphatase-like isoform X1 [KO:K01519] [EC:3.6.1.66]
110973665  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
110976819  xanthine dehydrogenase/oxidase-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
110981399  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
110973746  xanthine dehydrogenase/oxidase-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
110976709  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
110987942  uncharacterized protein LOC110987942 isoform X1 [KO:K01518] [EC:3.6.1.17]
110976509  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
110984758  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
110987589  guanine deaminase-like isoform X1 [KO:K01487] [EC:3.5.4.3]
110973091  guanylate kinase-like isoform X1 [KO:K00942] [EC:2.7.4.8]
110976922  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
110980173  ribonucleoside-diphosphate reductase subunit M2 B-like [KO:K10808] [EC:1.17.4.1]
110979313  ribonucleoside-diphosphate reductase subunit M2 B-like isoform X1 [KO:K10808] [EC:1.17.4.1]
110975316  HD domain-containing protein 2-like isoform X1 [KO:K07023] [EC:3.1.3.89]
110974553  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
110980095  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
110978247  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
110979349  adenylate cyclase type 6-like [KO:K08045] [EC:4.6.1.1]
110976938  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
110986264  adenylate cyclase type 10-like isoform X1 [KO:K11265] [EC:4.6.1.1]
110983731  guanylate cyclase soluble subunit alpha-2-like [KO:K12318] [EC:4.6.1.2]
110983732  guanylate cyclase soluble subunit beta-1-like isoform X1 [KO:K12319] [EC:4.6.1.2]
110988774  guanylate cyclase soluble subunit beta-2-like isoform X1 [KO:K12319] [EC:4.6.1.2]
110980490  guanylate cyclase soluble subunit beta-2-like [KO:K12319] [EC:4.6.1.2]
110981639  LOW QUALITY PROTEIN: retinal guanylyl cyclase 2-like [KO:K12322] [EC:4.6.1.2]
110987241  atrial natriuretic peptide receptor 2-like isoform X1 [KO:K12324] [EC:4.6.1.2]
110979674  guanylate cyclase 32E-like [KO:K01769] [EC:4.6.1.2]
110975095  soluble guanylate cyclase 88E-like isoform X1 [KO:K01769] [EC:4.6.1.2]
110988177  speract receptor-like [KO:K01769] [EC:4.6.1.2]
110979673  speract receptor-like [KO:K01769] [EC:4.6.1.2]
110991018  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
110976225  cGMP-dependent 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K18283] [EC:3.1.4.17]
110989096  cGMP-inhibited 3',5'-cyclic phosphodiesterase A-like isoform X1 [KO:K19021] [EC:3.1.4.17]
110989839  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like [KO:K13758]
110982457  cGMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13763] [EC:3.1.4.35]
110979413  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like isoform X1 [KO:K13761] [EC:3.1.4.35]
110978973  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like isoform X1 [KO:K13761] [EC:3.1.4.35]
110982709  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
110974504  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
110987097  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
110984544  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
110983967  adenylosuccinate synthetase isozyme 1 B-like isoform X1 [KO:K01939] [EC:6.3.4.4]
110988354  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
110983013  LOW QUALITY PROTEIN: AMP deaminase 2-like [KO:K01490] [EC:3.5.4.6]
110984975  adenosine kinase-like isoform X1 [KO:K00856] [EC:2.7.1.20]
110990847  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
110978222  adenosine deaminase-like isoform X1 [KO:K01488] [EC:3.5.4.4]
110978334  adenosine deaminase-like isoform X1 [KO:K01488] [EC:3.5.4.4]
110975510  adenosine deaminase-like isoform X1 [KO:K01488] [EC:3.5.4.4]
110987535  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
110987384  adenylate kinase 2, mitochondrial-like isoform X1 [KO:K00939] [EC:2.7.4.3]
110975235  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
110981343  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
110989635  GTP:AMP phosphotransferase AK3, mitochondrial-like isoform X1 [KO:K00944] [EC:2.7.4.10]
110983206  cancer-related nucleoside-triphosphatase-like isoform X1 [KO:K06928] [EC:3.6.1.15]
110979289  venom phosphodiesterase 2-like isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
110985706  venom phosphodiesterase 2-like isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
110985707  venom phosphodiesterase 2-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
110977429  cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like isoform X1 [KO:K13293] [EC:3.1.4.53]
110978747  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like isoform X1 [KO:K18436] [EC:3.1.4.53]
110987947  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like [KO:K18437] [EC:3.1.4.53]
110974296  bis(5'-adenosyl)-triphosphatase-like isoform X1 [KO:K01522] [EC:3.6.1.29]
110977502  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
110981412  uricase-like isoform X1 [KO:K00365] [EC:1.7.3.3]
110981429  uricase-like [KO:K00365] [EC:1.7.3.3]
110977186  5-hydroxyisourate hydrolase-like isoform X1 [KO:K07127] [EC:3.5.2.17]
110976487  allantoinase, mitochondrial-like isoform X1 [KO:K01466] [EC:3.5.2.5]
110979936  allantoicase-like [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
aplc00030  Pentose phosphate pathway
aplc00220  Arginine biosynthesis
aplc00250  Alanine, aspartate and glutamate metabolism
aplc00260  Glycine, serine and threonine metabolism
aplc00340  Histidine metabolism
aplc00630  Glyoxylate and dicarboxylate metabolism
aplc00730  Thiamine metabolism
aplc00740  Riboflavin metabolism
aplc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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