KEGG   PATHWAY: dfr00230
Entry
dfr00230                    Pathway                                
Name
Purine metabolism - Dermatophagoides farinae (American house dust mite)
Class
Metabolism; Nucleotide metabolism
Pathway map
dfr00230  Purine metabolism
dfr00230

Module
dfr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:dfr00230]
dfr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:dfr00230]
dfr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dfr00230]
dfr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:dfr00230]
dfr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:dfr00230]
Other DBs
GO: 0006163 0042278
Organism
Dermatophagoides farinae (American house dust mite) [GN:dfr]
Gene
124498330  ADP-ribose pyrophosphatase, mitochondrial-like [KO:K13988] [EC:3.6.1.13]
124494090  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
124499901  ADP-sugar pyrophosphatase-like [KO:K13987] [EC:3.6.1.13 3.6.1.58 2.7.7.96]
124490790  phosphoglucomutase-like [KO:K01835] [EC:5.4.2.2]
124491442  phosphoglucomutase-2-like [KO:K15779] [EC:5.4.2.2 5.4.2.7]
124493288  ribose-phosphate pyrophosphokinase 1-like isoform X1 [KO:K00948] [EC:2.7.6.1]
124494182  amidophosphoribosyltransferase-like [KO:K00764] [EC:2.4.2.14]
124493351  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
124493806  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
124493911  multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
124499193  adenylosuccinate lyase-like isoform X1 [KO:K01756] [EC:4.3.2.2]
124495863  bifunctional purine biosynthesis protein ATIC-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
124491547  adenine phosphoribosyltransferase-like [KO:K00759] [EC:2.4.2.7]
124492442  mannosylglucosyl-3-phosphoglycerate phosphatase-like [KO:K01081] [EC:3.1.3.5]
124500578  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
124495627  LOW QUALITY PROTEIN: snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
124498387  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
124497569  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
124492691  inosine-5'-monophosphate dehydrogenase 2-like isoform X1 [KO:K00088] [EC:1.1.1.205]
124499555  nucleoside diphosphate kinase A-like [KO:K00940] [EC:2.7.4.6]
124499819  LOW QUALITY PROTEIN: nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
124495545  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
124489968  ectonucleoside triphosphate diphosphohydrolase 1-like [KO:K01510] [EC:3.6.1.5]
124494111  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
124490474  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
124498232  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
124492218  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
124491728  LOW QUALITY PROTEIN: GMP reductase 1-like [KO:K00364] [EC:1.7.1.7]
124490211  guanylate kinase-like isoform X1 [KO:K00942] [EC:2.7.4.8]
124493630  LOW QUALITY PROTEIN: guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
124489936  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
124494830  LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
124495270  ribonucleoside-diphosphate reductase subunit M2 B-like [KO:K10808] [EC:1.17.4.1]
124495934  5'-deoxynucleotidase HDDC2-like [KO:K07023] [EC:3.1.3.89]
124498317  deoxynucleoside kinase-like [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
124499059  deoxynucleoside kinase-like isoform X1 [KO:K05961] [EC:2.7.1.145]
124496195  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
124498931  LOW QUALITY PROTEIN: uncharacterized protein LOC124498931 [KO:K08041] [EC:4.6.1.1]
124490750  uncharacterized protein LOC124490750 [KO:K08042] [EC:4.6.1.1]
124491170  adenylate cyclase type 5-like [KO:K08042] [EC:4.6.1.1]
124494734  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
124491502  adenylate cyclase type 2-like [KO:K08047] [EC:4.6.1.1]
124494863  adenylate cyclase type 8-like [KO:K08048] [EC:4.6.1.1]
124499966  head-specific guanylate cyclase-like isoform X1 [KO:K12318] [EC:4.6.1.2]
124492003  guanylate cyclase soluble subunit beta-1-like [KO:K12319] [EC:4.6.1.2]
124499082  guanylate cyclase soluble subunit beta-1-like isoform X1 [KO:K12319] [EC:4.6.1.2]
124497140  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
124492192  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
124493184  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
124493706  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
124499732  serine-rich adhesin for platelets-like [KO:K12323] [EC:4.6.1.2]
124495543  LOW QUALITY PROTEIN: receptor-type guanylate cyclase gcy-28-like [KO:K12323] [EC:4.6.1.2]
124491027  soluble guanylate cyclase 88E-like [KO:K01769] [EC:4.6.1.2]
124492247  receptor-type guanylate cyclase Gyc76C-like [KO:K01769] [EC:4.6.1.2]
124493549  guanylate cyclase 32E-like isoform X1 [KO:K01769] [EC:4.6.1.2]
124499985  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1-like [KO:K13755] [EC:3.1.4.17]
124497868  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like [KO:K13758]
124492351  cGMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
124496782  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
124499333  adenylosuccinate synthetase isozyme 1 A-like [KO:K01939] [EC:6.3.4.4]
124495808  AMP deaminase 2-like [KO:K01490] [EC:3.5.4.6]
124496524  adenosine kinase 1-like [KO:K00856] [EC:2.7.1.20]
124496525  adenosine kinase-like [KO:K00856] [EC:2.7.1.20]
124490906  adenosine kinase-like [KO:K00856] [EC:2.7.1.20]
124496972  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
124499706  adenylate kinase-like [KO:K00939] [EC:2.7.4.3]
124494925  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
124490902  cAMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13293] [EC:3.1.4.53]
124498269  LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K18436] [EC:3.1.4.53]
124493915  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like isoform X1 [KO:K18437] [EC:3.1.4.53]
124491254  bis(5'-adenosyl)-triphosphatase ENPP4-like [KO:K18424] [EC:3.6.1.29]
124497607  bis(5'-adenosyl)-triphosphatase ENPP4-like [KO:K18424] [EC:3.6.1.29]
124493760  bis(5'-adenosyl)-triphosphatase enpp4-like [KO:K18424] [EC:3.6.1.29]
124495443  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
dfr00030  Pentose phosphate pathway
dfr00220  Arginine biosynthesis
dfr00250  Alanine, aspartate and glutamate metabolism
dfr00260  Glycine, serine and threonine metabolism
dfr00340  Histidine metabolism
dfr00630  Glyoxylate and dicarboxylate metabolism
dfr00730  Thiamine metabolism
dfr00740  Riboflavin metabolism
dfr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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