KEGG   PATHWAY: esn00230
Entry
esn00230                    Pathway                                
Name
Purine metabolism - Eriocheir sinensis (Chinese mitten crab)
Class
Metabolism; Nucleotide metabolism
Pathway map
esn00230  Purine metabolism
esn00230

Module
esn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:esn00230]
esn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:esn00230]
esn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:esn00230]
esn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:esn00230]
esn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:esn00230]
esn_M00546  Purine degradation, xanthine => urea [PATH:esn00230]
esn_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:esn00230]
esn_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:esn00230]
Other DBs
GO: 0006163 0042278
Organism
Eriocheir sinensis (Chinese mitten crab) [GN:esn]
Gene
126980862  ADP-ribose pyrophosphatase, mitochondrial-like [KO:K13988] [EC:3.6.1.13]
127010354  phosphoglucomutase-like [KO:K01835] [EC:5.4.2.2]
127005421  phosphopentomutase-like [KO:K15779] [EC:5.4.2.2 5.4.2.7]
127009336  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
126999929  amidophosphoribosyltransferase-like isoform X1 [KO:K00764] [EC:2.4.2.14]
126985235  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
126995248  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
126999937  bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
126999779  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
126999424  bifunctional purine biosynthesis protein ATIC-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
126985339  uncharacterized protein LOC126985339 [KO:K00759] [EC:2.4.2.7]
127007274  5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
127009374  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
126992407  5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
127007236  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
127007238  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
126996011  purine nucleoside phosphorylase-like isoform X1 [KO:K03783] [EC:2.4.2.1]
126996892  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
126983183  inosine-5'-monophosphate dehydrogenase 1b-like isoform X1 [KO:K00088] [EC:1.1.1.205]
127006975  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
127009020  nucleoside diphosphate kinase 7-like isoform X1 [KO:K00940] [EC:2.7.4.6]
127001780  nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
126987749  ectonucleoside triphosphate diphosphohydrolase 1-like [KO:K01510] [EC:3.6.1.5]
126985381  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
127007811  ectonucleoside triphosphate diphosphohydrolase 5-like isoform X1 [KO:K01511] [EC:3.6.1.6]
126984212  U8 snoRNA-decapping enzyme-like isoform X1 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
126995534  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
126980375  uncharacterized protein LOC126980375 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126984540  uncharacterized protein LOC126984540 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
127001981  LOW QUALITY PROTEIN: xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126993215  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
127002687  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]-like isoform X1 [KO:K01518] [EC:3.6.1.17]
127006188  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
126998764  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
127005086  guanine deaminase-like [KO:K01487] [EC:3.5.4.3]
126985141  guanylate kinase-like isoform X1 [KO:K00942] [EC:2.7.4.8]
127007320  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
126984210  ribonucleoside-diphosphate reductase subunit M2 B-like isoform X1 [KO:K10808] [EC:1.17.4.1]
126988762  5'-deoxynucleotidase HDDC2-like [KO:K07023] [EC:3.1.3.89]
126997350  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
126985461  exopolyphosphatase PRUNE1-like isoform X1 [KO:K01514] [EC:3.6.1.11]
127000221  Ca(2+)/calmodulin-responsive adenylate cyclase-like isoform X1 [KO:K08041] [EC:4.6.1.1]
126980980  adenylate cyclase type 2-like isoform X1 [KO:K08042] [EC:4.6.1.1]
127002905  adenylate cyclase type 3-like isoform X1 [KO:K08043] [EC:4.6.1.1]
126984370  adenylate cyclase type 6-like isoform X1 [KO:K08045] [EC:4.6.1.1]
126983793  adenylate cyclase type 9-like isoform X1 [KO:K08049] [EC:4.6.1.1]
126987604  head-specific guanylate cyclase-like [KO:K12318] [EC:4.6.1.2]
126987605  guanylate cyclase soluble subunit beta-1-like isoform X1 [KO:K12319] [EC:4.6.1.2]
126995643  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
127009204  soluble guanylate cyclase 88E-like isoform X1 [KO:K01769] [EC:4.6.1.2]
127005356  soluble guanylate cyclase 89Db-like [KO:K01769] [EC:4.6.1.2]
127009875  receptor-type guanylate cyclase Gyc76C-like isoform X1 [KO:K01769] [EC:4.6.1.2]
127004979  guanylate cyclase 32E-like [KO:K01769] [EC:4.6.1.2]
126997061  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like isoform X1 [KO:K13755] [EC:3.1.4.17]
126984003  cGMP-dependent 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K18283] [EC:3.1.4.17]
126992662  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A-like [KO:K19021] [EC:3.1.4.17]
127002928  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like [KO:K13758]
126989704  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13763] [EC:3.1.4.35]
126985022  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [KO:K13761] [EC:3.1.4.35]
126992872  LOW QUALITY PROTEIN: high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [KO:K13761] [EC:3.1.4.35]
126997489  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
127002710  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
126981309  adenylosuccinate synthetase isozyme 1 A-like [KO:K01939] [EC:6.3.4.4]
127010379  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
127003241  uncharacterized protein LOC127003241 isoform X1 [KO:K00856] [EC:2.7.1.20]
127010352  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
127000420  adenosine deaminase-like isoform X1 [KO:K01488] [EC:3.5.4.4]
126981581  adenosine deaminase 2-like [KO:K19572] [EC:3.5.4.4]
127005428  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
126998020  adenylate kinase-like isoform X1 [KO:K00939] [EC:2.7.4.3]
127003011  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
127006639  GTP:AMP phosphotransferase AK3, mitochondrial-like isoform X1 [KO:K00944] [EC:2.7.4.10]
127001110  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
126992076  cancer-related nucleoside-triphosphatase homolog isoform X1 [KO:K06928] [EC:3.6.1.15]
126994165  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
126994316  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
126994409  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
127008394  venom phosphodiesterase 2-like isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
126983621  venom phosphodiesterase-like isoform X1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
126999664  venom phosphodiesterase-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
126995726  venom phosphodiesterase 2-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
127005002  venom phosphodiesterase-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
126998130  LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like [KO:K13293] [EC:3.1.4.53]
126988599  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like isoform X1 [KO:K18437] [EC:3.1.4.53]
126984639  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
126983077  uricase-like [KO:K00365] [EC:1.7.3.3]
126987724  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
126986673  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase-like [KO:K13485] [EC:4.1.1.97]
126982181  allantoinase-like [KO:K01466] [EC:3.5.2.5]
126985590  allantoicase-like isoform X1 [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
esn00030  Pentose phosphate pathway
esn00220  Arginine biosynthesis
esn00250  Alanine, aspartate and glutamate metabolism
esn00260  Glycine, serine and threonine metabolism
esn00340  Histidine metabolism
esn00630  Glyoxylate and dicarboxylate metabolism
esn00730  Thiamine metabolism
esn00740  Riboflavin metabolism
esn00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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