KEGG   PATHWAY: mcix00230
Entry
mcix00230                   Pathway                                
Name
Purine metabolism - Melitaea cinxia (Glanville fritillary)
Class
Metabolism; Nucleotide metabolism
Pathway map
mcix00230  Purine metabolism
mcix00230

Module
mcix_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mcix00230]
mcix_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mcix00230]
mcix_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mcix00230]
mcix_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mcix00230]
mcix_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mcix00230]
mcix_M00546  Purine degradation, xanthine => urea [PATH:mcix00230]
mcix_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mcix00230]
mcix_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mcix00230]
Other DBs
GO: 0006163 0042278
Organism
Melitaea cinxia (Glanville fritillary) [GN:mcix]
Gene
123656756  ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
123660311  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
123655961  phosphoglucomutase-2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
123658855  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
123659041  ribose-phosphate pyrophosphokinase 2-like [KO:K00948] [EC:2.7.6.1]
123666247  amidophosphoribosyltransferase-like [KO:K00764] [EC:2.4.2.14]
123656274  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
123654619  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
123661138  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
123657510  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
123655287  bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
123664679  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
123658371  cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
123665345  snake venom 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
123659915  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
123670511  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
123660281  nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
123653903  nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
123653914  nucleoside diphosphate kinase 7-like [KO:K00940] [EC:2.7.4.6]
123665530  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
123656823  apyrase [KO:K12304] [EC:3.6.1.6]
123663162  ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
123669114  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
123660935  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123660953  indole-3-acetaldehyde oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123661029  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123661044  indole-3-acetaldehyde oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123661049  indole-3-acetaldehyde oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123661053  LOW QUALITY PROTEIN: xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123661124  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123655845  xanthine dehydrogenase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123655872  xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
123661500  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
123660733  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
123665418  GMP reductase 1-like [KO:K00364] [EC:1.7.1.7]
123664262  guanine deaminase [KO:K01487] [EC:3.5.4.3]
123656280  guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
123655650  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
123665815  ribonucleoside-diphosphate reductase subunit M2 [KO:K10808] [EC:1.17.4.1]
123669854  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
123655306  deoxynucleoside kinase [KO:K05961] [EC:2.7.1.145]
123657209  deoxynucleoside kinase-like [KO:K05961] [EC:2.7.1.145]
123666032  exopolyphosphatase PRUNE1 [KO:K01514] [EC:3.6.1.11]
123653493  Ca(2+)/calmodulin-responsive adenylate cyclase-like [KO:K08041] [EC:4.6.1.1]
123660016  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
123669765  adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
123668537  adenylate cyclase type 6-like [KO:K08045] [EC:4.6.1.1]
123667163  adenylyl cyclase 78C-like [KO:K08048] [EC:4.6.1.1]
123670230  adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
123662682  head-specific guanylate cyclase [KO:K12318] [EC:4.6.1.2]
123662680  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
123666764  uncharacterized protein LOC123666764 [KO:K12322] [EC:4.6.1.2]
123661819  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
123664162  atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
123657475  guanylate cyclase 32E-like [KO:K01769] [EC:4.6.1.2]
123657925  soluble guanylate cyclase 89Db-like [KO:K01769] [EC:4.6.1.2]
123653586  receptor-type guanylate cyclase Gyc76C-like [KO:K01769] [EC:4.6.1.2]
123664961  soluble guanylate cyclase 88E [KO:K01769] [EC:4.6.1.2]
123668133  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 [KO:K13755] [EC:3.1.4.17]
123655958  cGMP-dependent 3',5'-cyclic phosphodiesterase-like [KO:K18283] [EC:3.1.4.17]
123670259  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
123665001  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13763] [EC:3.1.4.35]
123668559  probable 3',5'-cyclic phosphodiesterase pde-5 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
123658438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
123660645  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
123662028  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
123662430  AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
123660726  adenosine kinase [KO:K00856] [EC:2.7.1.20]
123663181  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
123663182  adenosine deaminase AGSA-like [KO:K19572] [EC:3.5.4.4]
123663252  adenosine deaminase 2-like [KO:K19572] [EC:3.5.4.4]
123669300  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
123669301  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
123654640  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
123655565  adenylate kinase [KO:K00939] [EC:2.7.4.3]
123666448  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
123670269  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
123660275  GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
123657117  nucleoside-triphosphatase THEP1 [KO:K06928] [EC:3.6.1.15]
123654348  cAMP-specific 3',5'-cyclic phosphodiesterase [KO:K13293] [EC:3.1.4.53]
123668508  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like [KO:K18436] [EC:3.1.4.53]
123661828  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8-like [KO:K18437] [EC:3.1.4.53]
123654226  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
123669732  uricase [KO:K00365] [EC:1.7.3.3]
123664553  probable 5-hydroxyisourate hydrolase R09H10.3 [KO:K07127] [EC:3.5.2.17]
123670130  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase-like [KO:K13485] [EC:4.1.1.97]
123653570  allantoinase-like [KO:K01466] [EC:3.5.2.5]
123654030  allantoinase-like [KO:K01466] [EC:3.5.2.5]
123655043  allantoicase-like [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mcix00030  Pentose phosphate pathway
mcix00220  Arginine biosynthesis
mcix00250  Alanine, aspartate and glutamate metabolism
mcix00260  Glycine, serine and threonine metabolism
mcix00340  Histidine metabolism
mcix00630  Glyoxylate and dicarboxylate metabolism
mcix00730  Thiamine metabolism
mcix00740  Riboflavin metabolism
mcix00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system