KEGG   PATHWAY: oki04260
Entry
oki04260                    Pathway                                
Name
Cardiac muscle contraction - Oncorhynchus kisutch (coho salmon)
Description
Contraction of the heart is a complex process initiated by the electrical excitation of cardiac myocytes (excitation-contraction coupling, ECC). In cardiac myocytes, Ca2+ influx induced by activation of voltage-dependent L-type Ca channels (DHP receptors) upon membrane depolarization triggers the release of Ca2+ via Ca2+ release channels (ryanodine receptors) of sarcoplasmic reticulum (SR) through a Ca2+ -induced Ca release (CICR) mechanism. Ca2+ ions released via the CICR mechanism diffuse through the cytosolic space to contractile proteins to bind to troponinC resulting in the release of inhibition induced by troponinI. The Ca2+ binding to troponinC thereby triggers the sliding of thin and thick filaments, that is, the activation of a crossbridge and subsequent cardiac force development and/or cell shortening. Recovery occurs as Ca2+ is pumped out of the cell by the Na+/Ca2+ exchanger (NCX) or is returned to the sarcoplasmic reticulum (SR) by sarco(endo)plasmic Ca2+ -ATPase (SERCA) pumps on the non-junctional region of the SR.
Class
Organismal Systems; Circulatory system
Pathway map
oki04260  Cardiac muscle contraction
oki04260

Other DBs
GO: 0060048
Organism
Oncorhynchus kisutch (coho salmon) [GN:oki]
Gene
109882530  LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1C-like [KO:K04850]
109869746  voltage-dependent L-type calcium channel subunit alpha-1D-like [KO:K04851]
109891346  voltage-dependent L-type calcium channel subunit alpha-1D-like isoform X1 [KO:K04851]
109907825  voltage-dependent L-type calcium channel subunit alpha-1D-like isoform X1 [KO:K04851]
109892681  voltage-dependent L-type calcium channel subunit alpha-1D-like isoform X1 [KO:K04851]
109869700  voltage-dependent L-type calcium channel subunit alpha-1F-like [KO:K04853]
109869670  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1 isoform X1 [KO:K04857]
109891316  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
109885052  LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F-like [KO:K04857]
109899957  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
109893290  voltage-dependent L-type calcium channel subunit beta-1 isoform X1 [KO:K04862]
109898387  voltage-dependent L-type calcium channel subunit beta-1-like isoform X1 [KO:K04862]
109899494  voltage-dependent L-type calcium channel subunit beta-2 isoform X1 [KO:K04863]
109909321  voltage-dependent L-type calcium channel subunit beta-2 isoform X1 [KO:K04863]
109869667  voltage-dependent L-type calcium channel subunit beta-4-like [KO:K04864]
109908510  voltage-dependent L-type calcium channel subunit beta-3 [KO:K04864]
109868051  voltage-dependent L-type calcium channel subunit beta-4-like isoform X1 [KO:K04865]
109871003  voltage-dependent L-type calcium channel subunit beta-4-like [KO:K04865]
109876649  voltage-dependent L-type calcium channel subunit beta-4-like isoform X1 [KO:K04865]
109876447  voltage-dependent L-type calcium channel subunit beta-4-like isoform X1 [KO:K04865]
109879081  voltage-dependent calcium channel subunit alpha-2/delta-1-like isoform X1 [KO:K04858]
109879069  voltage-dependent calcium channel subunit alpha-2/delta-1-like isoform X1 [KO:K04858]
109866961  voltage-dependent calcium channel subunit alpha-2/delta-1-like isoform X1 [KO:K04858]
109878204  LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-2-like [KO:K04859]
109892502  voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1 [KO:K04859]
109890883  voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1 [KO:K04859]
109891622  voltage-dependent calcium channel subunit alpha-2/delta-3-like [KO:K04860]
109869219  voltage-dependent calcium channel subunit alpha-2/delta-3 [KO:K04860]
109867631  voltage-dependent calcium channel subunit alpha-2/delta-4-like isoform X1 [KO:K04861]
109898656  voltage-dependent calcium channel subunit alpha-2/delta-4-like isoform X1 [KO:K04861]
116360523  voltage-dependent calcium channel subunit alpha-2/delta-4-like [KO:K04861]
116360578  voltage-dependent calcium channel subunit alpha-2/delta-4-like [KO:K04861]
116371365  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
109889573  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
116359841  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
109865839  voltage-dependent calcium channel gamma-1 subunit [KO:K04866]
109884643  LOW QUALITY PROTEIN: voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
109897406  voltage-dependent calcium channel gamma-2 subunit [KO:K04867]
116352857  voltage-dependent calcium channel gamma-2 subunit [KO:K04867]
116373136  voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
116359884  LOW QUALITY PROTEIN: voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
116360820  voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
116359842  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04869]
109865904  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04869]
109894879  voltage-dependent calcium channel gamma-4 subunit [KO:K04869]
109894776  voltage-dependent calcium channel gamma-5 subunit-like [KO:K04870]
116359988  voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
109865184  voltage-dependent calcium channel gamma-5 subunit-like [KO:K04870]
109880151  voltage-dependent calcium channel gamma-6 subunit [KO:K04871]
109868243  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
109903666  voltage-dependent calcium channel gamma-6 subunit [KO:K04871]
109908459  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
109880146  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
109906901  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
109868257  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
109904455  voltage-dependent calcium channel gamma-7 subunit [KO:K04872]
109868780  voltage-dependent calcium channel gamma-4 subunit isoform X1 [KO:K04873]
109907561  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
109903657  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
109887079  LOW QUALITY PROTEIN: ryanodine receptor 2-like [KO:K04962]
109889989  ryanodine receptor 2-like isoform X1 [KO:K04962]
109876547  ryanodine receptor 2-like isoform X1 [KO:K04962]
109899309  aspartyl/asparaginyl beta-hydroxylase isoform X15 [KO:K00476] [EC:1.14.11.16]
109909819  aspartyl/asparaginyl beta-hydroxylase-like isoform X1 [KO:K00476] [EC:1.14.11.16]
109872019  aspartyl/asparaginyl beta-hydroxylase isoform X1 [KO:K00476] [EC:1.14.11.16]
109890091  calsequestrin-2-like [KO:K23445]
109869582  calsequestrin-2 [KO:K23445]
109871057  calsequestrin-2-like [KO:K23445]
109879439  calsequestrin-2 [KO:K23445]
109900709  proteoglycan 4 isoform X1 [KO:K23449]
109866190  triadin isoform X2 [KO:K23449]
109868665  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like isoform X1 [KO:K05853] [EC:7.2.2.10]
109878225  sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
109873357  sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
109898208  sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like [KO:K05853] [EC:7.2.2.10]
109894770  sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
109893025  sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
109893087  atp2a1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [KO:K05853] [EC:7.2.2.10]
109865602  sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X2 [KO:K05853] [EC:7.2.2.10]
109894145  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [KO:K05853] [EC:7.2.2.10]
109874383  sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
109895781  sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
109868878  troponin C, slow skeletal and cardiac muscles-like [KO:K05865]
109869297  troponin C, slow skeletal and cardiac muscles-like [KO:K05865]
109907772  troponin C, slow skeletal and cardiac muscles isoform X2 [KO:K05865]
109869106  troponin T, cardiac muscle isoforms isoform X1 [KO:K12045]
109890144  troponin T, cardiac muscle isoforms isoform X1 [KO:K12045]
109896767  troponin T, cardiac muscle-like isoform X1 [KO:K12045]
109879104  troponin T, cardiac muscle-like isoform X1 [KO:K12045]
109867073  troponin T, cardiac muscle-like isoform X1 [KO:K12045]
109889364  tropomyosin alpha-1 chain-like isoform X1 [KO:K10373]
109878802  tropomyosin alpha-1 chain isoform X1 [KO:K10373]
109907418  tropomyosin alpha-3 chain isoform X4 [KO:K10373]
109867553  tropomyosin alpha-1 chain isoform X1 [KO:K10373]
109885897  tropomyosin alpha-1 chain isoform X5 [KO:K10373]
109868374  tropomyosin beta chain isoform X1 [KO:K10374]
109901959  tropomyosin alpha-3 chain-like isoform X1 [KO:K09290]
109903558  tropomyosin alpha-3 chain isoform X1 [KO:K09290]
109908096  tropomyosin alpha-3 chain-like isoform X1 [KO:K09290]
109889191  tropomyosin alpha-1 chain-like isoform X1 [KO:K10375]
109874576  tropomyosin alpha-1 chain isoform X1 [KO:K10375]
109902439  tropomyosin alpha-1 chain isoform X1 [KO:K10375]
109888949  actin, alpha skeletal muscle 2-like [KO:K12314]
109889641  actin, alpha cardiac muscle 1-like [KO:K12314]
109870195  actin, alpha skeletal muscle 2-like [KO:K12314]
109900088  actin, alpha skeletal muscle 2-like [KO:K12314]
109865772  actin, alpha skeletal muscle 2-like [KO:K12314]
109881280  actin, alpha cardiac [KO:K12314]
109894386  actc1; actin, alpha cardiac muscle 1 [KO:K12314]
109894530  actin, alpha cardiac-like [KO:K12314]
109900499  actin, alpha cardiac-like [KO:K12314]
109866379  actin, alpha cardiac muscle 1-like [KO:K12314]
109867094  actin, alpha cardiac muscle 1-like [KO:K12314]
109904013  actin, alpha cardiac-like [KO:K12314]
109879242  myosin-7-like [KO:K17751]
109872382  myosin-6 [KO:K17751]
109909622  myosin-7-like [KO:K17751]
109909772  myosin-7-like [KO:K17751]
109899356  myosin-7-like [KO:K17751]
109887764  myosin-7-like [KO:K17751]
109899359  myosin-7-like [KO:K17751]
109874689  myosin-7-like [KO:K17751]
109901933  myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
109872005  myosin light chain 1, cardiac muscle-like [KO:K12749]
109875174  myosin light chain 1, cardiac muscle [KO:K12749]
109892214  myosin light chain 4-like isoform X1 [KO:K12750]
109895485  cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
109867180  cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
109886140  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
4955083  CYTB; cytochrome b [KO:K00412]
109890758  cytochrome c1, heme protein, mitochondrial [KO:K00413]
109891064  cytochrome c1, heme protein, mitochondrial-like [KO:K00413]
109897383  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
109890979  cytochrome b-c1 complex subunit 1, mitochondrial-like [KO:K00414]
109869904  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
109900045  cytochrome b-c1 complex subunit 2, mitochondrial-like isoform X1 [KO:K00415]
109889057  cytochrome b-c1 complex subunit 6, mitochondrial-like [KO:K00416]
109872021  cytochrome b-c1 complex subunit 6, mitochondrial [KO:K00416]
109902315  cytochrome b-c1 complex subunit 6, mitochondrial-like [KO:K00416]
109907224  cytochrome b-c1 complex subunit 7-like isoform X1 [KO:K00417]
109903373  cytochrome b-c1 complex subunit 7 [KO:K00417]
109878357  cytochrome b-c1 complex subunit 8-like [KO:K00418]
109879490  cytochrome b-c1 complex subunit 8-like [KO:K00418]
109892073  cytochrome b-c1 complex subunit 9 [KO:K00419]
109875017  cytochrome b-c1 complex subunit 10 [KO:K00420]
4955084  COX3; cytochrome c oxidase subunit III [KO:K02262]
4955088  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
4955090  COX2; cytochrome c oxidase subunit II [KO:K02261]
109908854  cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform X1 [KO:K02263]
109869225  cytochrome c oxidase subunit 4 isoform 2, mitochondrial-like [KO:K02263]
109880923  cytochrome c oxidase subunit 4 isoform 1, mitochondrial-like [KO:K02263]
109895354  cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
109907973  cytochrome c oxidase subunit 4 isoform 2, mitochondrial-like [KO:K02263]
109907975  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
109887203  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
109897696  cytochrome c oxidase subunit 5A, mitochondrial-like [KO:K02264]
109884273  cytochrome c oxidase subunit 5A, mitochondrial-like [KO:K02264]
109895423  cytochrome c oxidase subunit 5A, mitochondrial-like [KO:K02264]
109868618  cytochrome c oxidase subunit 5B, mitochondrial-like [KO:K02265]
109889760  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
109874099  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
109878445  cytochrome c oxidase subunit 6A, mitochondrial-like [KO:K02266]
109878683  cytochrome c oxidase subunit 6A, mitochondrial [KO:K02266]
109898727  cytochrome c oxidase subunit 6A, mitochondrial [KO:K02266]
109868248  cytochrome c oxidase subunit 6B1-like [KO:K02267]
109879278  cytochrome c oxidase subunit 6B1-like [KO:K02267]
109865532  cytochrome c oxidase subunit 6B1-like [KO:K02267]
109903673  cytochrome c oxidase subunit 6B1 isoform X1 [KO:K02267]
109890784  cytochrome c oxidase subunit 6C-1-like [KO:K02268]
109890944  cytochrome c oxidase subunit 6C-1 [KO:K02268]
109908931  cytochrome c oxidase subunit 7A2, mitochondrial-like isoform X1 [KO:K02270]
109889831  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
109865526  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
109899080  LOW QUALITY PROTEIN: cytochrome c oxidase subunit 7A-related protein, mitochondrial-like [KO:K02270]
109894608  cytochrome c oxidase subunit 7A2, mitochondrial-like [KO:K02270]
109866624  cytochrome c oxidase subunit 7A2, mitochondrial [KO:K02270]
109903928  cytochrome c oxidase subunit 7A2, mitochondrial-like [KO:K02270]
109892782  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
109875925  cytochrome c oxidase subunit 7C, mitochondrial-like [KO:K02272]
109895054  cytochrome c oxidase subunit 7C, mitochondrial-like [KO:K02272]
109889645  cytochrome c oxidase subunit 8B, mitochondrial-like [KO:K02273]
109873867  cytochrome c oxidase subunit 8B, mitochondrial-like [KO:K02273]
109900285  cytochrome c oxidase subunit 8B, mitochondrial [KO:K02273]
109872825  cytochrome c oxidase subunit 8B, mitochondrial [KO:K02273]
109867536  cytochrome c oxidase subunit 8B, mitochondrial-like [KO:K02273]
109875525  sodium/calcium exchanger 1 isoform X1 [KO:K05849]
109905551  sodium/calcium exchanger 2-like [KO:K05849]
109888821  sodium/calcium exchanger 1-like isoform X1 [KO:K05849]
109882762  sodium/calcium exchanger 3-like isoform X1 [KO:K05849]
109890265  sodium/calcium exchanger 1-like isoform X1 [KO:K05849]
109893835  sodium/calcium exchanger 2-like [KO:K05849]
109899794  sodium/calcium exchanger 1 isoform X1 [KO:K05849]
109883919  LOW QUALITY PROTEIN: sodium/calcium exchanger 1 [KO:K05849]
109909002  sodium/calcium exchanger 2-like isoform X1 [KO:K05849]
109873420  sodium/calcium exchanger 1 [KO:K05849]
109873494  sodium/calcium exchanger 2 isoform X1 [KO:K05849]
109874438  sodium/calcium exchanger 1-like [KO:K05849]
109884732  sodium/calcium exchanger 3-like [KO:K05849]
109905127  sodium/hydrogen exchanger 6-like [KO:K12041]
109884402  slc9a7; sodium/hydrogen exchanger 7 isoform X1 [KO:K12041]
109864722  sodium/hydrogen exchanger 6 isoform X1 [KO:K12041]
109874040  sodium/hydrogen exchanger 6 isoform X1 [KO:K12041]
109901771  sodium/potassium-transporting ATPase subunit alpha-3-like isoform X1 [KO:K01539] [EC:7.2.2.13]
109871624  sodium/potassium-transporting ATPase subunit alpha-2-like [KO:K01539] [EC:7.2.2.13]
109880653  sodium/potassium-transporting ATPase subunit alpha-1 isoform X1 [KO:K01539] [EC:7.2.2.13]
109903622  sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
109874670  sodium/potassium-transporting ATPase subunit alpha-2-like [KO:K01539] [EC:7.2.2.13]
109864422  sodium/potassium-transporting ATPase subunit alpha-3-like isoform X1 [KO:K01539] [EC:7.2.2.13]
109882909  sodium/potassium-transporting ATPase subunit alpha-1-like isoform X1 [KO:K01539] [EC:7.2.2.13]
109882906  sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
109907540  sodium/potassium-transporting ATPase subunit alpha-3 isoform X1 [KO:K01539] [EC:7.2.2.13]
109884069  sodium/potassium-transporting ATPase subunit alpha-1-like [KO:K01539] [EC:7.2.2.13]
109884073  sodium/potassium-transporting ATPase subunit alpha-1 isoform X1 [KO:K01539] [EC:7.2.2.13]
109905314  protein ATP1B4-like [KO:K01540]
109875678  sodium/potassium-transporting ATPase subunit beta-2-like [KO:K01540]
109906280  sodium/potassium-transporting ATPase subunit beta-3-like [KO:K01540]
109884062  sodium/potassium-transporting ATPase subunit beta-233-like [KO:K01540]
109871845  sodium/potassium-transporting ATPase subunit beta-3-like [KO:K01540]
109890491  sodium/potassium-transporting ATPase subunit beta-233 [KO:K01540]
109874478  sodium/potassium-transporting ATPase subunit beta-3-like [KO:K01540]
116353892  sodium/potassium-transporting ATPase subunit beta-2-like isoform X1 [KO:K01540]
116354032  sodium/potassium-transporting ATPase subunit beta-233-like [KO:K01540]
116354033  sodium/potassium-transporting ATPase subunit beta-233-like [KO:K01540]
109892675  sodium/potassium-transporting ATPase subunit beta-2-like isoform X2 [KO:K01540]
109864461  sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
109864880  atp1b4; protein ATP1B4 [KO:K01540]
109880054  sodium/potassium-transporting ATPase subunit beta-233-like [KO:K01540]
109905437  uncharacterized protein LOC109905437 isoform X1 [KO:K01538]
109909562  sodium/potassium-transporting ATPase subunit gamma-like [KO:K01538]
109909783  sodium/hydrogen exchanger 1 [KO:K05742]
109877270  sodium/hydrogen exchanger 1-like [KO:K05742]
109903432  Na(+)/H(+) exchanger beta isoform X1 [KO:K05742]
Compound
C00076  Calcium cation
C00080  H+
C00238  Potassium cation
C01330  Sodium cation
Reference
PMID:17988210
  Authors
Bers DM
  Title
Calcium cycling and signaling in cardiac myocytes.
  Journal
Annu Rev Physiol 70:23-49 (2008)
DOI:10.1146/annurev.physiol.70.113006.100455
Reference
PMID:11805843
  Authors
Bers DM
  Title
Cardiac excitation-contraction coupling.
  Journal
Nature 415:198-205 (2002)
DOI:10.1038/415198a
Reference
PMID:16799263
  Authors
Endoh M
  Title
Signal transduction and Ca2+ signaling in intact myocardium.
  Journal
J Pharmacol Sci 100:525-37 (2006)
DOI:10.1254/jphs.CPJ06009X
Reference
PMID:18981594
  Authors
Endoh M
  Title
Cardiac Ca2+ signaling and Ca2+ sensitizers.
  Journal
Circ J 72:1915-25 (2008)
DOI:10.1253/circj.CJ-08-0838
Reference
PMID:16552170
  Authors
Bers DM, Despa S
  Title
Cardiac myocytes Ca2+ and Na+ regulation in normal and failing hearts.
  Journal
J Pharmacol Sci 100:315-22 (2006)
DOI:10.1254/jphs.CPJ06001X
Reference
PMID:10747208
  Authors
Gordon AM, Homsher E, Regnier M
  Title
Regulation of contraction in striated muscle.
  Journal
Physiol Rev 80:853-924 (2000)
DOI:10.1152/physrev.2000.80.2.853
Reference
PMID:16701909
  Authors
Phrommintikul A, Chattipakorn N
  Title
Roles of cardiac ryanodine receptor in heart failure and sudden cardiac death.
  Journal
Int J Cardiol 112:142-52 (2006)
DOI:10.1016/j.ijcard.2005.11.106
Reference
PMID:16096350
  Authors
Lacinova L
  Title
Voltage-dependent calcium channels.
  Journal
Gen Physiol Biophys 24 Suppl 1:1-78 (2005)
Reference
PMID:12763850
  Authors
Lingrel J, Moseley A, Dostanic I, Cougnon M, He S, James P, Woo A, O'Connor K, Neumann J
  Title
Functional roles of the alpha isoforms of the Na,K-ATPase.
  Journal
Ann N Y Acad Sci 986:354-9 (2003)
DOI:10.1111/j.1749-6632.2003.tb07214.x
Reference
PMID:11294886
  Authors
Berg JS, Powell BC, Cheney RE
  Title
A millennial myosin census.
  Journal
Mol Biol Cell 12:780-94 (2001)
DOI:10.1091/mbc.12.4.780
Reference
PMID:15736582
  Authors
Parmacek MS, Solaro RJ
  Title
Biology of the troponin complex in cardiac myocytes.
  Journal
Prog Cardiovasc Dis 47:159-76 (2004)
DOI:10.1016/j.pcad.2004.07.003
Reference
PMID:14659803
  Authors
Yamashita H, Sugiura S, Fujita H, Yasuda S, Nagai R, Saeki Y, Sunagawa K, Sugi H
  Title
Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin-myosin interaction.
  Journal
Cardiovasc Res 60:580-8 (2003)
DOI:10.1016/j.cardiores.2003.09.011
Reference
PMID:19403607
  Authors
Pritchard TJ, Kranias EG
  Title
Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis.
  Journal
J Physiol 587:3125-33 (2009)
DOI:10.1113/jphysiol.2009.172171
Reference
PMID:28596175
  Authors
Landstrom AP, Dobrev D, Wehrens XHT
  Title
Calcium Signaling and Cardiac Arrhythmias.
  Journal
Circ Res 120:1969-1993 (2017)
DOI:10.1161/CIRCRESAHA.117.310083
Related
pathway
oki04020  Calcium signaling pathway
KO pathway
ko04260   
LinkDB

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