KEGG   PATHWAY: pee04150
Entry
pee04150                    Pathway                                
Name
mTOR signaling pathway - Phycodurus eques (leafy seadragon)
Description
The mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 contains mTOR, Raptor, PRAS40, Deptor, mLST8, Tel2 and Tti1. mTORC1 is activated by the presence of growth factors, amino acids, energy status, stress and oxygen levels to regulate several biological processes, including lipid metabolism, autophagy, protein synthesis and ribosome biogenesis. On the other hand, mTORC2, which consists of mTOR, mSin1, Rictor, Protor, Deptor, mLST8, Tel2 and Tti1, responds to growth factors and controls cytoskeletal organization, metabolism and survival.
Class
Environmental Information Processing; Signal transduction
Pathway map
pee04150  mTOR signaling pathway
pee04150

Organism
Phycodurus eques (leafy seadragon) [GN:pee]
Gene
133403042  slc7a5; large neutral amino acids transporter small subunit 1 [KO:K13780]
133405105  large neutral amino acids transporter small subunit 1-like [KO:K13780]
133401875  amino acid transporter heavy chain SLC3A2-like isoform X1 [KO:K06519]
133397733  slc3a2a; solute carrier family 3 member 2a [KO:K06519]
133405438  si:dkey-202g17.3; amino acid transporter heavy chain SLC3A2 [KO:K06519]
133414021  slc38a9; neutral amino acid transporter 9 isoform X1 [KO:K14995]
133396474  atp6v1ab; LOW QUALITY PROTEIN: V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
133416226  V-type proton ATPase catalytic subunit A-like [KO:K02145] [EC:7.1.2.2]
133409426  atp6v1ba; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
133401154  V-type proton ATPase subunit C 1-A-like [KO:K02148]
133395535  atp6v1c1b; V-type proton ATPase subunit C 1-B [KO:K02148]
133416859  atp6v1d; V-type proton ATPase subunit D [KO:K02149]
133402788  V-type proton ATPase subunit E 1-like isoform X1 [KO:K02150]
133397029  atp6v1e1b; V-type proton ATPase subunit E 1 isoform X1 [KO:K02150]
133397433  atp6v1f; V-type proton ATPase subunit F [KO:K02151]
133413510  atp6v1g1; V-type proton ATPase subunit G 1 [KO:K02152]
133411376  atp6v1h; V-type proton ATPase subunit H isoform X1 [KO:K02144]
133405547  lamtor1; ragulator complex protein LAMTOR1 [KO:K20397]
133401641  lamtor2; ragulator complex protein LAMTOR2 [KO:K20398]
133412350  lamtor3; ragulator complex protein LAMTOR3 [KO:K04370]
133397519  lamtor4; ragulator complex protein LAMTOR4 [KO:K20399]
133411689  lamtor5; ragulator complex protein LAMTOR5 [KO:K16344]
133401477  flcn; folliculin isoform X1 [KO:K09594]
133415812  fnip1; folliculin-interacting protein 1 isoform X1 [KO:K20400]
133416459  rraga; ras-related GTP-binding protein A isoform X1 [KO:K16185]
133402107  rragca; ras-related GTP binding Ca isoform X1 [KO:K16186]
133396007  ras-related GTP-binding protein C-like [KO:K16186]
133395486  sesn2; sestrin-2 isoform X1 [KO:K20394]
133400291  castor1; cytosolic arginine sensor for mTORC1 subunit 1 isoform X1 [KO:K23080]
133416327  castor2; cytosolic arginine sensor for mTORC1 subunit 2 [KO:K23081]
133401602  mios; GATOR2 complex protein MIOS isoform X1 [KO:K20407]
133401139  seh1l; nucleoporin SEH1 isoform X1 [KO:K14299]
133417579  wdr24; GATOR2 complex protein WDR24 [KO:K20408]
133417033  wdr59; GATOR2 complex protein WDR59 isoform X1 [KO:K20409]
133408306  sec13; protein SEC13 homolog [KO:K14004]
133412130  depdc5; GATOR1 complex protein DEPDC5 isoform X1 [KO:K20404]
133409143  nprl2; GATOR complex protein NPRL2 isoform X1 [KO:K20405]
133414964  nprl3; GATOR complex protein NPRL3 isoform X1 [KO:K20406]
133401852  S-phase kinase-associated protein 2-like isoform X1 [KO:K03875]
133413965  skp2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
133396528  rnf152; E3 ubiquitin-protein ligase rnf152 [KO:K15705] [EC:2.3.2.27]
133404352  rptor; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
133415320  akt1s1; uncharacterized protein akt1s1 isoform X1 [KO:K16184]
133399868  mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
133401782  deptor; DEP domain-containing mTOR-interacting protein isoform X1 [KO:K20402]
133409092  si:dkeyp-97e7.9; DEP domain-containing mTOR-interacting protein isoform X1 [KO:K20402]
133418182  mlst8; target of rapamycin complex subunit lst8 [KO:K08266]
133418284  telo2; telomere length regulation protein TEL2 homolog isoform X1 [KO:K11137]
133400119  tti1; TELO2-interacting protein 1 homolog [KO:K20403]
133400133  clip1a; CAP-Gly domain-containing linker protein 1 isoform X1 [KO:K10421]
133413405  clip1b; CAP-Gly domain-containing linker protein 1 isoform X1 [KO:K10421]
133401817  growth factor receptor-bound protein 10-like isoform X1 [KO:K20064]
133396186  growth factor receptor-bound protein 10-like isoform X1 [KO:K20064]
133411679  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
133396313  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
133408914  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
133396920  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
133416701  lpin1b; LOW QUALITY PROTEIN: phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
133413379  ulk1b; serine/threonine-protein kinase ULK1 isoform X1 [KO:K21357] [EC:2.7.11.1]
133399657  ulk1a; LOW QUALITY PROTEIN: serine/threonine-protein kinase ULK1a [KO:K21357] [EC:2.7.11.1]
133400517  eif4ebp1; eukaryotic translation initiation factor 4E-binding protein 1 [KO:K07205]
133413876  eukaryotic translation initiation factor 4E-binding protein 1-like [KO:K07205]
133411907  eif4e2; eukaryotic translation initiation factor 4E type 2 isoform X1 [KO:K03259]
133412430  eif4eb; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4eb [KO:K03259]
133407609  eukaryotic translation initiation factor 4E-1A-like isoform X1 [KO:K03259]
133409445  eif4e1c; eukaryotic translation initiation factor 4E family member 1c [KO:K03259]
133397886  eif4e2rs1; eukaryotic translation initiation factor 4E family member 2 related sequence 1 isoform X1 [KO:K03259]
133404013  ribosomal protein S6 kinase beta-2-like isoform X1 [KO:K04688] [EC:2.7.11.1]
133416429  rps6kb1a; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
133405275  rps6kb1b; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
133408234  eukaryotic translation initiation factor 4B-like isoform X1 [KO:K03258]
133404041  rps6; 40S ribosomal protein S6 [KO:K02991]
133414938  strada; STE20-related kinase adapter protein alpha isoform X1 [KO:K08271]
133406010  stradb; STE20-related kinase adapter protein beta isoform X1 [KO:K17532]
133411839  stk11; serine/threonine-protein kinase STK11 [KO:K07298] [EC:2.7.11.1]
133407974  cab39l1; calcium binding protein 39, like 1 [KO:K08272]
133410945  cab39l; calcium-binding protein 39-like [KO:K08272]
133405292  cab39; calcium-binding protein 39 [KO:K08272]
133413496  prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 [KO:K07198] [EC:2.7.11.31]
133406008  prkaa2; LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase catalytic subunit alpha-2 [KO:K07198] [EC:2.7.11.31]
133413608  tsc1b; TSC complex subunit 1b isoform X1 [KO:K07206]
133399605  tsc1a; TSC complex subunit 1a isoform X1 [KO:K07206]
133404591  tsc2; tuberin isoform X1 [KO:K07207]
133406060  tbc1d7; TBC1 domain family member 7 isoform X1 [KO:K20396]
133411944  rheb; GTP-binding protein Rheb [KO:K07208]
133409142  rhebl1; ras homolog, mTORC1 binding like 1 [KO:K07208]
133417859  ddit4; DNA damage-inducible transcript 4 protein [KO:K08270]
133409796  DNA damage-inducible transcript 4 protein-like [KO:K08270]
133402444  wnt1; protein Wnt-1 [KO:K03209]
133401643  protein Wnt-2b-A-like [KO:K00182]
133402674  wnt2; protein Wnt-2 [KO:K00182]
133408601  protein Wnt-2b-A-like [KO:K00182]
133417778  wnt3; proto-oncogene Wnt-3 [KO:K00312]
133411188  wnt3a; protein Wnt-3a [KO:K00312]
133401423  wnt4b; wingless-type MMTV integration site family, member 4b [KO:K00408]
133408497  wnt4; protein Wnt-4a [KO:K00408]
133413256  protein Wnt-5a-like [KO:K00444]
133397126  wnt5b; protein Wnt-5b [KO:K00444]
133410472  wnt6b; protein Wnt-6 [KO:K00445]
133402627  wnt7bb; protein Wnt-7b [KO:K00572]
133397071  wnt7ba; protein Wnt-7b [KO:K00572]
133415974  protein Wnt-7a [KO:K00572]
133407726  protein Wnt-8-like [KO:K00714]
133407745  protein Wnt-8a-like [KO:K00714]
133409611  wnt8b; protein Wnt-8b [KO:K00714]
133414833  wnt9b; protein Wnt-9b [KO:K01064]
133411584  wnt9a; protein Wnt-9a [KO:K01064]
133402386  wnt10b; protein Wnt-10b [KO:K01357]
133410800  wnt10a; protein Wnt-10a [KO:K01357]
133415871  wnt11; protein Wnt-11 [KO:K01384]
133397478  wnt16; protein Wnt-16 [KO:K01558]
133410370  frizzled-7-A-like [KO:K02432]
133410988  frizzled-7-A-like [KO:K02432]
133415309  frizzled-2-like [KO:K02235]
133397040  frizzled-3-like isoform X1 [KO:K02329]
133417187  fzd3a; frizzled-3a isoform X1 [KO:K02329]
133405280  fzd4; frizzled-4 isoform X1 [KO:K02354]
133396390  fzd8a; frizzled-8a [KO:K02375]
133410579  fzd5; frizzled-5 [KO:K02375]
133411470  frizzled-8-like [KO:K02375]
133401168  frizzled-6-like isoform X1 [KO:K02376]
133400496  fzd10; frizzled-10 [KO:K02842]
133404903  fzd9b; LOW QUALITY PROTEIN: frizzled-9b [KO:K02842]
133396963  lrp6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
133401871  dvl1a; segment polarity protein dishevelled homolog DVL-1 [KO:K02353]
133398113  dvl2; segment polarity protein dishevelled homolog DVL-2 [KO:K02353]
133411254  segment polarity protein dishevelled homolog DVL-3-like [KO:K02353]
133410316  gsk3ba; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
133395629  tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
133401422  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
133399974  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
133407894  LOW QUALITY PROTEIN: insulin-like [KO:K04526]
133416067  LOW QUALITY PROTEIN: insulin-like [KO:K04526]
133416094  insulin-like [KO:K04526]
133415074  igf3; insulin-like growth factor 3 [KO:K05459]
133397194  igf1; insulin-like growth factor I [KO:K05459]
133406145  insrb; insulin receptor b [KO:K04527] [EC:2.7.10.1]
133411346  insra; insulin receptor a [KO:K04527] [EC:2.7.10.1]
133403348  igf1ra; insulin-like growth factor 1a receptor [KO:K05087] [EC:2.7.10.1]
133398212  igf1rb; insulin-like growth factor 1b receptor [KO:K05087] [EC:2.7.10.1]
133415512  grb2b; growth factor receptor-bound protein 2b isoform X1 [KO:K04364]
133412669  sos2; son of sevenless homolog 2 [KO:K03099]
133403931  son of sevenless homolog 1-like isoform X1 [KO:K03099]
133403096  GTPase HRas [KO:K02833]
133403059  kras; GTPase KRas isoform X1 [KO:K07827]
133414337  zgc:55558; GTPase KRas isoform X1 [KO:K07827]
133396939  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
133409227  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
133402354  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
133406476  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
133400250  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
133414520  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
133412492  rps6ka1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
133408037  rps6kal; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
133396523  rps6ka2; ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
133396672  rps6ka3b; ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
133398112  si:ch73-335l21.1; insulin receptor substrate 1-B [KO:K16172]
133416420  si:ch211-284e13.4; LOW QUALITY PROTEIN: insulin receptor substrate 1-B [KO:K16172]
133400156  phosphatidylinositol 3-kinase regulatory subunit alpha-like [KO:K02649]
133406435  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
133413324  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
133411281  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
133411283  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
133397873  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
133404795  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
133404801  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
133411165  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
133405962  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like isoform X1 [KO:K00922] [EC:2.7.1.153]
133417605  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
133409852  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
133418280  pdpk1b; 3-phosphoinositide-dependent protein kinase 1 [KO:K06276] [EC:2.7.11.1]
133412376  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
133409516  akt3a; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
133404039  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
133404960  akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
133417719  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
133410156  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
133413317  mapkap1; target of rapamycin complex 2 subunit MAPKAP1 isoform X1 [KO:K20410]
133399688  rapamycin-insensitive companion of mTOR-like isoform X1 [KO:K08267]
133402892  prr5a; proline-rich protein 5a isoform X1 [KO:K20411]
133397155  proline-rich protein 5-like isoform X1 [KO:K20411]
133408263  rho-related GTP-binding protein RhoA-B [KO:K04513]
133408288  rho-related GTP-binding protein RhoA-D [KO:K04513]
133408356  rho-related GTP-binding protein RhoA-C-like [KO:K04513]
133404335  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
133414406  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
133404595  prkcaa; protein kinase C, alpha, a [KO:K02677] [EC:2.7.11.13]
133414687  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
133403675  LOW QUALITY PROTEIN: protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
133401470  prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
133395970  si:ch211-195b13.1; STKc_SGK domain-containing protein isoform X1 [KO:K13302] [EC:2.7.11.1]
133416757  sgk1; serine/threonine-protein kinase Sgk1 isoform X1 [KO:K13302] [EC:2.7.11.1]
Compound
C00020  AMP
C00062  L-Arginine
C00123  L-Leucine
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:27304501
  Authors
Kennedy BK, Lamming DW
  Title
The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging.
  Journal
Cell Metab 23:990-1003 (2016)
DOI:10.1016/j.cmet.2016.05.009
Reference
PMID:24556838
  Authors
Shimobayashi M, Hall MN
  Title
Making new contacts: the mTOR network in metabolism and signalling crosstalk.
  Journal
Nat Rev Mol Cell Biol 15:155-62 (2014)
DOI:10.1038/nrm3757
Reference
PMID:25242279
  Authors
Huang K, Fingar DC
  Title
Growing knowledge of the mTOR signaling network.
  Journal
Semin Cell Dev Biol 36:79-90 (2014)
DOI:10.1016/j.semcdb.2014.09.011
Reference
PMID:26269525
  Authors
Bockaert J, Marin P
  Title
mTOR in Brain Physiology and Pathologies.
  Journal
Physiol Rev 95:1157-87 (2015)
DOI:10.1152/physrev.00038.2014
Reference
PMID:26185979
  Authors
Caron A, Richard D, Laplante M
  Title
The Roles of mTOR Complexes in Lipid Metabolism.
  Journal
Annu Rev Nutr 35:321-48 (2015)
DOI:10.1146/annurev-nutr-071714-034355
Reference
PMID:26658722
  Authors
Shimobayashi M, Hall MN
  Title
Multiple amino acid sensing inputs to mTORC1.
  Journal
Cell Res 26:7-20 (2016)
DOI:10.1038/cr.2015.146
Reference
PMID:24698685
  Authors
Bar-Peled L, Sabatini DM
  Title
Regulation of mTORC1 by amino acids.
  Journal
Trends Cell Biol 24:400-6 (2014)
DOI:10.1016/j.tcb.2014.03.003
Reference
PMID:26046644
  Authors
Fingar DC
  Title
Rag Ubiquitination Recruits a GATOR1: Attenuation of Amino Acid-Induced mTORC1 Signaling.
  Journal
Mol Cell 58:713-5 (2015)
DOI:10.1016/j.molcel.2015.05.029
Reference
PMID:26700098
  Authors
Cai H, Dong LQ, Liu F
  Title
Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects.
  Journal
Trends Pharmacol Sci 37:303-17 (2016)
DOI:10.1016/j.tips.2015.11.011
Reference
PMID:24842496
  Authors
Eyre TA, Collins GP, Goldstone AH, Cwynarski K
  Title
Time now to TORC the TORC? New developments in mTOR pathway inhibition in lymphoid malignancies.
  Journal
Br J Haematol 166:336-51 (2014)
DOI:10.1111/bjh.12945
Reference
PMID:23465396
  Authors
Jewell JL, Guan KL
  Title
Nutrient signaling to mTOR and cell growth.
  Journal
Trends Biochem Sci 38:233-42 (2013)
DOI:10.1016/j.tibs.2013.01.004
Reference
PMID:23421405
  Authors
Wood TL, Bercury KK, Cifelli SE, Mursch LE, Min J, Dai J, Macklin WB
  Title
mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.
  Journal
ASN Neuro 5:e00108 (2013)
DOI:10.1042/AN20120092
Reference
PMID:23694989
  Authors
Kim SG, Buel GR, Blenis J
  Title
Nutrient regulation of the mTOR complex 1 signaling pathway.
  Journal
Mol Cells 35:463-73 (2013)
DOI:10.1007/s10059-013-0138-2
Reference
PMID:19812304
  Authors
Laplante M, Sabatini DM
  Title
mTOR signaling at a glance.
  Journal
J Cell Sci 122:3589-94 (2009)
DOI:10.1242/jcs.051011
Reference
PMID:16756488
  Authors
Alessi DR, Sakamoto K, Bayascas JR
  Title
LKB1-dependent signaling pathways.
  Journal
Annu Rev Biochem 75:137-63 (2006)
DOI:10.1146/annurev.biochem.75.103004.142702
Reference
PMID:27027448
  Authors
Dan HC, Antonia RJ, Baldwin AS
  Title
PI3K/Akt promotes feedforward mTORC2 activation through IKKalpha.
  Journal
Oncotarget 7:21064-75 (2016)
DOI:10.18632/oncotarget.8383
Reference
PMID:28283069
  Authors
Saxton RA, Sabatini DM
  Title
mTOR Signaling in Growth, Metabolism, and Disease.
  Journal
Cell 168:960-976 (2017)
DOI:10.1016/j.cell.2017.02.004
Related
pathway
pee00561  Glycerolipid metabolism
pee04010  MAPK signaling pathway
pee04140  Autophagy - animal
pee04810  Regulation of actin cytoskeleton
pee04910  Insulin signaling pathway
KO pathway
ko04150   
LinkDB

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