KEGG   PATHWAY: phyp04814
Entry
phyp04814                   Pathway                                
Name
Motor proteins - Pangasianodon hypophthalmus (striped catfish)
Class
Cellular Processes; Cell motility
Pathway map
phyp04814  Motor proteins
phyp04814

Organism
Pangasianodon hypophthalmus (striped catfish) [GN:phyp]
Gene
113529706  dync1h1; cytoplasmic dynein 1 heavy chain 1 isoform X1 [KO:K10413]
113544532  dync2h1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
113545863  cytoplasmic dynein 1 intermediate chain 2-like [KO:K10415]
113536069  dync1i1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
113526392  cytoplasmic dynein 1 intermediate chain 1-like isoform X1 [KO:K10415]
113526269  dync1i2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
113524461  cytoplasmic dynein 1 light intermediate chain 1-like [KO:K10416]
113540854  dync1li2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
113538699  dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
113532510  dynein light chain 2, cytoplasmic [KO:K10418]
113533112  dynein light chain 1, cytoplasmic [KO:K10418]
113541542  dynein light chain 2, cytoplasmic-like [KO:K10418]
113529995  dynlrb2; dynein light chain roadblock-type 2 [KO:K10419]
113538117  dynlrb1; dynein light chain roadblock-type 1 [KO:K10419]
113547444  dynlt3; dynein light chain Tctex-type 3 [KO:K10420]
113540565  tctex1d1; tctex1 domain-containing protein 1 [KO:K25421]
113540084  dnah2; dynein heavy chain 2, axonemal [KO:K10408]
113547350  dnah6; dynein heavy chain 6, axonemal [KO:K10408]
113543878  dnah7; dynein heavy chain 7, axonemal [KO:K10408]
113530654  dnah12; dynein heavy chain 12, axonemal [KO:K10408]
113527468  dnah17; dynein heavy chain 17, axonemal isoform X1 [KO:K10408]
113524651  dnah3; dynein heavy chain 3, axonemal [KO:K10408]
113537184  dnah10; dynein heavy chain 10, axonemal [KO:K10408]
113527534  dnah9; dynein heavy chain 9, axonemal [KO:K10408]
113538176  dynein beta chain, ciliary-like [KO:K10408]
113542626  dynein heavy chain 11, axonemal-like isoform X1 [KO:K10408]
113534004  dnah5; dynein heavy chain 5, axonemal isoform X1 [KO:K10408]
113539461  dnah1; dynein heavy chain 1, axonemal [KO:K10408]
113535447  dnai1; dynein intermediate chain 1, axonemal [KO:K10409]
113527746  dnai2; dynein intermediate chain 2, axonemal [KO:K11143]
113530547  wdr63; WD repeat-containing protein 63 [KO:K24722]
113529129  wdr78; WD repeat-containing protein 78 [KO:K24723]
113526538  dnali1; axonemal dynein light intermediate polypeptide 1 [KO:K10410]
113534017  dnal1; dynein light chain 1, axonemal [KO:K10411]
113527897  dynein light chain 4, axonemal [KO:K10412]
113547414  dynein light chain 4, axonemal-like [KO:K10412]
113545762  dynactin subunit 1-like isoform X1 [KO:K04648]
113541402  dctn1; dynactin subunit 1 isoform X1 [KO:K04648]
113530126  dctn2; dynactin subunit 2 isoform X1 [KO:K10424]
113526412  dctn3; dynactin subunit 3 [KO:K10425]
113547112  dctn4; dynactin subunit 4 [KO:K10426]
113527933  dctn5; dynactin subunit 5 [KO:K10427]
113545707  dctn6; dynactin subunit 6 [KO:K10428]
113545270  actr10; actin-related protein 10 [KO:K16576]
113531169  capza1; F-actin-capping protein subunit alpha-1 [KO:K10364]
113534427  F-actin-capping protein subunit alpha-1-like [KO:K10364]
113531263  BICD family-like cargo adapter 2 [KO:K16756]
113524477  bicdl1; BICD family-like cargo adapter 1 isoform X1 [KO:K16756]
113543245  BICD family-like cargo adapter 1 isoform X1 [KO:K16756]
113531429  hook3; protein Hook homolog 3 [KO:K16536]
113537938  tubulin alpha-1B chain [KO:K07374]
113534677  tubulin alpha chain, testis-specific-like [KO:K07374]
113535495  tubulin alpha chain-like [KO:K07374]
113536346  tubulin alpha chain-like [KO:K07374]
113530925  tubulin alpha-1B chain-like [KO:K07374]
113530926  tubulin alpha-1B chain [KO:K07374]
113530927  tubulin alpha-1C chain [KO:K07374]
113526172  tubulin alpha chain [KO:K07374]
113537410  tubulin beta-4B chain-like [KO:K07375]
113545479  tubulin beta-5 chain [KO:K07375]
113542485  tubb; tubulin beta chain [KO:K07375]
113525552  tubulin beta chain-like [KO:K07375]
113545939  tubb1; tubulin beta-1 chain [KO:K07375]
113546088  tubulin beta-1 chain [KO:K07375]
113528958  tubulin beta-4B chain-like [KO:K07375]
113546256  tubulin beta-4B chain-like [KO:K07375]
113526844  tubb3; tubulin beta-3 chain [KO:K07375]
113531398  tubb4b; tubulin beta-4B chain [KO:K07375]
113528623  tubg1; tubulin gamma-1 chain [KO:K10389]
113532760  tubd1; tubulin delta chain isoform X1 [KO:K10390]
113527258  kif5b; kinesin-1 heavy chain isoform X1 [KO:K10396]
113533587  kinesin heavy chain-like [KO:K10396]
113534881  kinesin heavy chain-like [KO:K10396]
113531431  kif5a; kinesin heavy chain [KO:K10396]
113538180  kinesin heavy chain-like [KO:K10396]
113545875  klc1; kinesin light chain 1 isoform X1 [KO:K10407]
113540436  kinesin light chain 1-like isoform X1 [KO:K10407]
113532771  kinesin light chain 1-like isoform X1 [KO:K10407]
113528769  kinesin light chain 1-like [KO:K10407]
113540385  klc2; kinesin light chain 2 [KO:K10407]
113529954  kif3a; kinesin-like protein KIF3A [KO:K10394]
113530675  kif3b; kinesin-like protein KIF3B [KO:K20196]
113546834  kifap3; kinesin-associated protein 3 [KO:K25388]
113539120  kinesin-associated protein 3-like [KO:K25388]
113529258  kif3c; kinesin-like protein KIF3C isoform X1 [KO:K20197]
113538667  kinesin-like protein KIF3B isoform X1 [KO:K20197]
113538085  kif17; kinesin-like protein KIF17 isoform X1 [KO:K20198]
113525450  LOW QUALITY PROTEIN: kinesin-like protein KIF1C [KO:K10392]
113526704  kinesin-like protein KIF1A isoform X1 [KO:K10392]
113531416  kinesin-like protein KIF1C [KO:K10392]
113530603  kif1b; kinesin-like protein KIF1B [KO:K10392]
113539300  kinesin-like protein KIF1A isoform X1 [KO:K10392]
113531736  kif13b; kinesin-like protein KIF13B isoform X1 [KO:K17914]
113532866  kinesin-like protein KIF13A [KO:K17914]
113533996  kinesin-like protein KIF13B isoform X1 [KO:K17914]
113530716  kif14; kinesin-like protein KIF14 isoform X1 [KO:K17915]
113537374  kif16b; kinesin-like protein KIF16B isoform X1 [KO:K17916]
113538637  stAR-related lipid transfer protein 9-like [KO:K16491]
113541394  kif4a; chromosome-associated kinesin KIF4A [KO:K10395]
113536639  kif7; kinesin-like protein KIF7 [KO:K18806]
113529754  kinesin-like protein KIF21A isoform X1 [KO:K24185]
113531825  kinesin-like protein KIF21A isoform X1 [KO:K24185]
113539520  kif21b; kinesin-like protein KIF21B isoform X1 [KO:K24185]
113545144  kif11; kinesin-like protein KIF11 [KO:K10398]
113540119  kinesin-like protein KIF20A [KO:K10402]
113527772  kif20b; kinesin-like protein KIF20B isoform X1 [KO:K10402]
113543094  kif20a; kinesin-like protein KIF20A [KO:K10402]
113547720  kinesin-like protein KIF20B [KO:K10402]
113534815  kif23; kinesin-like protein KIF23 [KO:K17387]
113537744  cenpe; centromere-associated protein E [KO:K11498]
113540800  kif18a; kinesin-like protein KIF18A [KO:K10401]
113527745  kif19; kinesin-like protein KIF19 [KO:K26157]
113539998  kif9; kinesin-like protein KIF9 [KO:K10397]
113545105  kif6; kinesin-like protein KIF6 [KO:K10397]
113527121  kif22; kinesin-like protein KIF22 [KO:K10403]
113546863  kinesin-like protein KIF26B isoform X1 [KO:K10404]
113525531  kif26b; kinesin-like protein KIF26B isoform X1 [KO:K10404]
113538685  kinesin-like protein KIF26A isoform X1 [KO:K10404]
113547648  kinesin-like protein KIF26A isoform X1 [KO:K10404]
113541922  kif15; kinesin-like protein KIF15 [KO:K10400]
113535069  kinesin-like protein KIF2A isoform X1 [KO:K10393]
113539849  kif2c; kinesin-like protein KIF2C isoform X1 [KO:K10393]
113544902  kinesin-like protein KIF2A isoform X1 [KO:K10393]
113543648  carboxy-terminal kinesin 2-like isoform X1 [KO:K10405]
113526518  kifc3; kinesin-like protein KIFC3 isoform X1 [KO:K10406]
113542421  kinesin-like protein KIFC3 isoform X1 [KO:K10406]
113531939  kif25; kinesin-like protein KIF25 [KO:K18627]
113534978  unconventional myosin-If-like [KO:K10356]
113526296  myo1b; unconventional myosin-Ib isoform X1 [KO:K10356]
113526846  unconventional myosin-Ie-like [KO:K10356]
113531168  unconventional myosin-Ic isoform X1 [KO:K10356]
113543892  unconventional myosin-Ig-like [KO:K10356]
113539140  myo1c; unconventional myosin-Ic isoform X1 [KO:K10356]
113524974  myo1h; unconventional myosin-Ih [KO:K10356]
113540905  myo1e; unconventional myosin-Ie isoform X1 [KO:K10356]
113527223  myo1d; unconventional myosin-Id [KO:K10356]
113545448  myo3a; myosin-IIIa [KO:K08834] [EC:2.7.11.1]
113526161  myo3b; myosin-IIIb [KO:K08834] [EC:2.7.11.1]
113535543  unconventional myosin-Vb-like [KO:K10357]
113534764  myo5a; unconventional myosin-Va [KO:K10357]
113541555  myo5b; unconventional myosin-Vb isoform X1 [KO:K10357]
113529579  unconventional myosin-Va-like [KO:K10357]
113529580  myo5c; unconventional myosin-Vc isoform X1 [KO:K10357]
113529177  unconventional myosin-VI-like isoform X1 [KO:K10358]
113538891  unconventional myosin-VI [KO:K10358]
113541537  unconventional myosin-VIIa-like [KO:K10359]
113526987  myo7a; unconventional myosin-VIIa [KO:K10359]
113527823  unconventional myosin-VIIa-like [KO:K21868]
113539299  unconventional myosin-VIIa-like isoform X1 [KO:K21868]
113536486  myo9b; unconventional myosin-IXb isoform X1 [KO:K10360]
113536632  myo9a; unconventional myosin-IXa isoform X1 [KO:K10360]
113540237  unconventional myosin-IXb-like isoform X1 [KO:K10360]
113538457  unconventional myosin-X-like isoform X1 [KO:K12559]
113543120  myo10; unconventional myosin-X [KO:K12559]
113525433  unconventional myosin-X-like [KO:K12559]
113535777  LOW QUALITY PROTEIN: unconventional myosin-XV-like [KO:K10361]
113527488  myo15b; myosin XVB isoform X1 [KO:K10361]
113536260  myo15a; unconventional myosin-XV isoform X1 [KO:K10361]
113525860  myo16; unconventional myosin-XVI isoform X1 [KO:K17481]
113532808  unconventional myosin-XVIIIa-like isoform X1 [KO:K10362]
113544796  myo18b; unconventional myosin-XVIIIb isoform X1 [KO:K10362]
113544892  myo18a; unconventional myosin-XVIIIa isoform X1 [KO:K10362]
113531298  myo19; unconventional myosin-XIX [KO:K25838]
113532653  myosin heavy chain, fast skeletal muscle-like [KO:K24220]
113539456  myosin heavy chain, fast skeletal muscle-like [KO:K24220]
113539522  myosin heavy chain, fast skeletal muscle isoform X1 [KO:K24220]
113539523  myosin heavy chain, fast skeletal muscle-like isoform X1 [KO:K24220]
113531012  myosin heavy chain, fast skeletal muscle-like [KO:K24220]
113526615  myosin-7-like [KO:K17751]
113526616  myosin-7-like [KO:K17751]
113526618  myosin-7-like [KO:K17751]
113543184  myosin-7-like [KO:K17751]
113525053  myosin-11-like isoform X1 [KO:K10352]
113534318  myh9; myosin-9 isoform X1 [KO:K10352]
113525577  myosin-9-like [KO:K10352]
113526040  myosin light chain 1, skeletal muscle isoform-like [KO:K05738]
113531068  myosin light chain 1, cardiac muscle-like [KO:K12750]
113543886  myosin light chain 4-like [KO:K12750]
113527501  myosin light polypeptide 6-like [KO:K12750]
113545905  myosin light polypeptide 6-like [KO:K12751]
113530262  myosin light polypeptide 6 isoform X1 [KO:K12751]
113543209  myosin light chain 5-like isoform X1 [KO:K12753]
113546002  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
113530437  myosin regulatory light polypeptide 9-like [KO:K12755]
113529804  myosin regulatory light polypeptide 9 [KO:K12755]
113524150  myosin regulatory light chain 2B, cardiac muscle isoform-like [KO:K12756]
113543162  myosin regulatory light chain 2B, cardiac muscle isoform-like [KO:K12756]
113540283  myosin regulatory light chain 2, smooth muscle minor isoform-like [KO:K12757]
113540393  myosin regulatory light chain 2, smooth muscle minor isoform [KO:K12757]
113528434  myosin regulatory light chain 2, skeletal muscle isoform type 2 [KO:K12758]
113547537  myosin regulatory light chain 2, skeletal muscle isoform type 2-like [KO:K12758]
113541505  actin, alpha skeletal muscle 2 [KO:K10354]
113527698  acta2; actin, aortic smooth muscle [KO:K12313]
113537359  actin, alpha cardiac-like [KO:K12314]
113524817  actin, alpha cardiac muscle 1 [KO:K12314]
113526557  actin, alpha cardiac muscle 1-like [KO:K12314]
113546513  actin, alpha cardiac muscle 1-like [KO:K12314]
113531857  actin, alpha cardiac [KO:K12314]
113538705  actin, alpha cardiac muscle 1-like [KO:K12314]
113529562  actin, alpha skeletal muscle 2-like [KO:K12314]
113535507  actin, cytoplasmic 1 isoform X1 [KO:K05692]
113535975  actb; actin, cytoplasmic 1 [KO:K05692]
113538013  troponin C, slow skeletal and cardiac muscles [KO:K05865]
113530766  troponin C, slow skeletal and cardiac muscles-like [KO:K05865]
113529382  troponin I, slow skeletal muscle-like isoform X1 [KO:K10371]
113529383  troponin I, slow skeletal muscle-like [KO:K10371]
113531744  troponin I, slow skeletal muscle-like [KO:K10371]
113528756  troponin I, slow skeletal muscle-like [KO:K10371]
113528818  troponin I, slow skeletal muscle-like [KO:K10371]
113532364  troponin I, slow skeletal muscle-like isoform X1 [KO:K10371]
113526731  troponin I, slow skeletal muscle-like [KO:K10371]
113536280  tnni1; troponin I, slow skeletal muscle [KO:K10371]
113525300  troponin T, slow skeletal muscle-like isoform X1 [KO:K10372]
113530767  troponin C, skeletal muscle [KO:K12042]
113530269  troponin C, skeletal muscle-like [KO:K12042]
113529873  troponin I, fast skeletal muscle-like [KO:K12043]
113529874  troponin I, fast skeletal muscle-like [KO:K12043]
113529733  troponin I, fast skeletal muscle-like [KO:K12043]
113529734  troponin I, fast skeletal muscle-like [KO:K12043]
113529735  troponin I, fast skeletal muscle-like [KO:K12043]
113546770  troponin T, fast skeletal muscle isoforms-like isoform X1 [KO:K12046]
113529939  troponin T, fast skeletal muscle isoforms-like isoform X1 [KO:K12046]
113529142  troponin T, cardiac muscle isoforms-like [KO:K12045]
113526555  tnnt2; troponin T, cardiac muscle isoform X1 [KO:K12045]
113532165  troponin T, fast skeletal muscle-like isoform X1 [KO:K12045]
113529987  tpm1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
113536635  tropomyosin alpha-1 chain-like [KO:K10373]
113543574  tropomyosin beta chain isoform X1 [KO:K10374]
113543831  tropomyosin alpha-3 chain isoform X1 [KO:K09290]
113543071  tropomyosin alpha-4 chain-like isoform X1 [KO:K09290]
113533505  tropomyosin alpha-1 chain-like isoform X1 [KO:K10375]
113536483  tpm4; tropomyosin alpha-4 chain isoform X1 [KO:K10375]
Reference
PMID:21092854
  Authors
Hirokawa N, Niwa S, Tanaka Y
  Title
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.
  Journal
Neuron 68:610-38 (2010)
DOI:10.1016/j.neuron.2010.09.039
Reference
PMID:25470043 (PDB:4RH7)
  Authors
Schmidt H, Zalyte R, Urnavicius L, Carter AP
  Title
Structure of human cytoplasmic dynein-2 primed for its power stroke.
  Journal
Nature 518:435-438 (2015)
DOI:10.1038/nature14023
Reference
PMID:22398446 (PDB:3VKG 3VKH)
  Authors
Kon T, Oyama T, Shimo-Kon R, Imamula K, Shima T, Sutoh K, Kurisu G
  Title
The 2.8 A crystal structure of the dynein motor domain.
  Journal
Nature 484:345-50 (2012)
DOI:10.1038/nature10955
Reference
PMID:22997337 (PDB:3J1T 3J1U)
  Authors
Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE
  Title
Structural basis for microtubule binding and release by dynein.
  Journal
Science 337:1532-1536 (2012)
DOI:10.1126/science.1224151
Reference
PMID:26410600
  Authors
Gibbs KL, Greensmith L, Schiavo G
  Title
Regulation of Axonal Transport by Protein Kinases.
  Journal
Trends Biochem Sci 40:597-610 (2015)
DOI:10.1016/j.tibs.2015.08.003
Reference
PMID:28602352 (PDB:5NUG 5NVS 5NVU 5NW4)
  Authors
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
  Title
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
  Journal
Cell 169:1303-1314.e18 (2017)
DOI:10.1016/j.cell.2017.05.025
Reference
PMID:25814576 (PDB:5ADX 5AFR 5AFU)
  Authors
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
  Title
The structure of the dynactin complex and its interaction with dynein.
  Journal
Science 347:1441-1446 (2015)
DOI:10.1126/science.aaa4080
Reference
PMID:29420470 (PDB:5OWO 6F1T 6F1U 6F1V 6F1Y 6F1Z 6F38 6F3A)
  Authors
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
  Title
Cryo-EM shows how dynactin recruits two dyneins for faster movement.
  Journal
Nature 554:202-206 (2018)
DOI:10.1038/nature25462
Reference
PMID:29662141
  Authors
Reck-Peterson SL, Redwine WB, Vale RD, Carter AP
  Title
The cytoplasmic dynein transport machinery and its many cargoes.
  Journal
Nat Rev Mol Cell Biol 19:382-398 (2018)
DOI:10.1038/s41580-018-0004-3
Reference
PMID:23434508 (PDB:3J2U)
  Authors
Asenjo AB, Chatterjee C, Tan D, DePaoli V, Rice WJ, Diaz-Avalos R, Silvestry M, Sosa H
  Title
Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases.
  Journal
Cell Rep 3:759-68 (2013)
DOI:10.1016/j.celrep.2013.01.030
Reference
PMID:10338210 (PDB:1B7T)
  Authors
Houdusse A, Kalabokis VN, Himmel D, Szent-Gyorgyi AG, Cohen C
  Title
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head.
  Journal
Cell 97:459-70 (1999)
DOI:10.1016/s0092-8674(00)80756-4
Reference
PMID:9428521 (PDB:3KIN)
  Authors
Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E
  Title
The crystal structure of dimeric kinesin and implications for microtubule-dependent motility.
  Journal
Cell 91:985-94 (1997)
DOI:10.1016/s0092-8674(00)80489-4
Reference
PMID:8316857 (PDB:2MYS)
  Authors
Rayment I, Rypniewski WR, Schmidt-Base K, Smith R, Tomchick DR, Benning MM, Winkelmann DA, Wesenberg G, Holden HM
  Title
Three-dimensional structure of myosin subfragment-1: a molecular motor.
  Journal
Science 261:50-8 (1993)
DOI:10.1126/science.8316857
Reference
PMID:20428469
  Authors
Parker D, Bryant Z, Delp SL
  Title
Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics.
  Journal
Cell Mol Bioeng 2:366-374 (2009)
DOI:10.1007/s12195-009-0084-4
Reference
PMID:21314430
  Authors
Dominguez R, Holmes KC
  Title
Actin structure and function.
  Journal
Annu Rev Biophys 40:169-86 (2011)
DOI:10.1146/annurev-biophys-042910-155359
Reference
PMID:31919429 (PDB:6KN7 6KN8)
  Authors
Yamada Y, Namba K, Fujii T
  Title
Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
  Journal
Nat Commun 11:153 (2020)
DOI:10.1038/s41467-019-14008-1
Reference
PMID:33912943
  Authors
Kruppa AJ, Buss F
  Title
Motor proteins at the mitochondria-cytoskeleton interface.
  Journal
J Cell Sci 134:239092 (2021)
DOI:10.1242/jcs.226084
KO pathway
ko04814   
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