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ENTRY	nt06267
Name	Small cell lung cancer
Category	Disease view; Cancer
Pathway	hsa05222 Small cell lung cancer
Disease	H00013 Small cell lung cancer
Display	drug-target relation   disease type

PI3K signaling N00220    PTEN ⊣ PIP3 → AKT N00051    PTEN* ⌿ PIP3 → AKT N00052    PTEN* ⌿ PIP3 → AKT   Cell cycle N00090        (MYC+MAX) ⊣ ZBTB17 ⇒ CDKN2B ⊣ (CCND+CDK4/6) → RB1 ⌿ E2F N00088        (MYC*+MAX) ⊣ ZBTB17 ⇒ CDKN2B ⊣ (CCND+CDK4/6) → RB1 ⌿ E2F N00089                (MYC*+MAX) ⇒ (CCND+CDK4/6) → RB1 ⌿ E2F N00091            (SCF+SKP2) ⊣ CDKN1B ⊣ ((CCNA,CCNE)+CDK2) → RB1 ⌿ E2F N00092    (MYC*+MAX) ⇒ CKS1B → (SCF+SKP2) ⊣ CDKN1B ⊣ (CCNE+CDK2) → RB1 ⌿ E2F N00074                        RB1* ⌿ E2F N00075                        RB1* ⌿ E2F   Apoptosis N00098    (PMAIP1,BBC3,BAD,B.. ⊣ (BCL2,BCL2L1) ⊣ (BAX,BAK1) → CYCS = APAF1 → CASP9 → (CASP3,CASP7) N00100        BCL2* ⊣ BAX → CYCS = APAF1 → CASP9 → (CASP3,CASP7)   Transcription N00115    TP53* ⌿ (CDKN1A,GADD45,BAX..