KEGG   PATHWAY: cge05200
Entry
cge05200                    Pathway                                
Name
Pathways in cancer - Cricetulus griseus (Chinese hamster)
Class
Human Diseases; Cancer: overview
Pathway map
cge05200  Pathways in cancer
cge05200

Organism
Cricetulus griseus (Chinese hamster) [GN:cge]
Gene
100758377  Dcc; netrin receptor DCC isoform X2 [KO:K06765]
100689061  Casp3; caspase-3 [KO:K02187] [EC:3.4.22.56]
103160479  caspase-9-like [KO:K04399] [EC:3.4.22.62]
100689370  caspase-9 [KO:K04399] [EC:3.4.22.62]
113833881  caspase-9-like [KO:K04399] [EC:3.4.22.62]
100751324  Appl1; DCC-interacting protein 13-alpha isoform X2 [KO:K08733]
100758185  Cdh1; cadherin-1 [KO:K05689]
100773307  Ctnnb1; catenin beta-1 [KO:K02105]
100763869  Ctnna3; catenin alpha-3 isoform X2 [KO:K05691]
100754399  Ctnna1; catenin alpha-1 [KO:K05691]
100766706  Ctnna2; catenin alpha-2 isoform X4 [KO:K05691]
100758169  Axin1; axin-1 isoform X1 [KO:K02157]
100750382  Axin2; axin-2 [KO:K04385]
100750563  Apc; adenomatous polyposis coli protein isoform X2 [KO:K02085]
100767273  Apc2; adenomatous polyposis coli protein 2 isoform X2 [KO:K02085]
100760865  Gsk3b; glycogen synthase kinase-3 beta isoform X7 [KO:K03083] [EC:2.7.11.26]
100757390  Tcf7; transcription factor 7 isoform X2 [KO:K02620]
100753225  Tcf7l1; transcription factor 7-like 1 isoform X2 [KO:K04490]
100758400  Tcf7l2; transcription factor 7-like 2 isoform X33 [KO:K04491]
100761200  Lef1; lymphoid enhancer-binding factor 1 isoform X3 [KO:K04492]
100769162  baculoviral IAP repeat-containing protein 5 isoform X2 [KO:K08731]
118237651  Birc5; baculoviral IAP repeat-containing protein 5 isoform X2 [KO:K08731]
100773301  Myc; myc proto-oncogene protein isoform X2 [KO:K04377]
100689063  Ccnd1; G1/S-specific cyclin-D1 [KO:K04503]
100766046  Wnt1; proto-oncogene Wnt-1 [KO:K03209]
100761413  Wnt2b; protein Wnt-2b [KO:K00182]
100752722  Wnt2; protein Wnt-2 [KO:K00182]
100764164  Wnt3a; protein Wnt-3a isoform X2 [KO:K00312]
100774849  proto-oncogene Wnt-3 isoform X2 [KO:K00312]
100769003  Wnt4; protein Wnt-4 isoform X3 [KO:K00408]
100753089  Wnt5a; protein Wnt-5a [KO:K00444]
100753017  Wnt5b; protein Wnt-5b isoform X2 [KO:K00444]
100751289  Wnt6; protein Wnt-6 isoform X2 [KO:K00445]
100772978  Wnt7a; protein Wnt-7a isoform X2 [KO:K00572]
100755799  Wnt7b; protein Wnt-7b isoform X1 [KO:K00572]
100775075  Wnt8b; protein Wnt-8b [KO:K00714]
100752907  Wnt8a; protein Wnt-8a isoform X2 [KO:K00714]
100766088  Wnt9b; protein Wnt-9b isoform X2 [KO:K01064]
100764466  Wnt9a; protein Wnt-9a isoform X2 [KO:K01064]
100770174  Wnt10a; protein Wnt-10a [KO:K01357]
100766340  Wnt10b; protein Wnt-10b [KO:K01357]
100774690  Wnt11; protein Wnt-11 isoform X1 [KO:K01384]
100764115  Wnt16; protein Wnt-16 [KO:K01558]
100766658  Fzd7; frizzled-7 isoform X2 [KO:K02432]
100770917  Fzd1; frizzled-1 isoform X2 [KO:K02432]
100763109  Fzd2; frizzled-2 isoform X2 [KO:K02235]
100751712  Fzd3; frizzled-3 isoform X1 [KO:K02329]
100756296  Fzd4; frizzled-4 [KO:K02354]
100762351  Fzd5; frizzled-5 isoform X2 [KO:K02375]
113834637  frizzled-8 [KO:K02375]
100774509  Fzd6; frizzled-6 isoform X2 [KO:K02376]
100755785  Fzd10; frizzled-10 isoform X2 [KO:K02842]
100761155  Fzd9; frizzled-9 isoform X2 [KO:K02842]
100763041  Lrp5; low-density lipoprotein receptor-related protein 5 isoform X2 [KO:K03068]
100772150  Lrp6; low-density lipoprotein receptor-related protein 6 isoform X2 [KO:K03068]
100770288  Dvl1; segment polarity protein dishevelled homolog DVL-1 isoform X4 [KO:K02353]
100762587  Dvl2; segment polarity protein dishevelled homolog DVL-2 isoform X2 [KO:K02353]
100773535  Dvl3; segment polarity protein dishevelled homolog DVL-3 isoform X2 [KO:K02353]
103163256  proto-oncogene FRAT1 isoform X2 [KO:K03069]
100758062  LOW QUALITY PROTEIN: proto-oncogene FRAT1 isoform X2 [KO:K03069]
103160455  Frat1; LOW QUALITY PROTEIN: proto-oncogene FRAT1 isoform X2 [KO:K03069]
100764150  LOW QUALITY PROTEIN: proto-oncogene FRAT1-like isoform X2 [KO:K03069]
100761548  proto-oncogene FRAT1-like isoform X2 [KO:K03069]
113838049  proto-oncogene FRAT1-like [KO:K03069]
113838894  proto-oncogene FRAT1-like [KO:K03069]
113838895  proto-oncogene FRAT1-like [KO:K03069]
113834828  LOW QUALITY PROTEIN: GSK-3-binding protein FRAT2-like [KO:K03096]
100754947  F2; prothrombin [KO:K01313] [EC:3.4.21.5]
100773858  Agt; angiotensinogen [KO:K09821]
100758351  F2r; proteinase-activated receptor 1 isoform X2 [KO:K03914]
100757293  F2rl3; proteinase-activated receptor 4 [KO:K04236]
100757522  Lpar1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
100753903  Lpar2; lysophosphatidic acid receptor 2 [KO:K04291]
100759265  Lpar3; lysophosphatidic acid receptor 3 [KO:K04294]
100752179  Lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
100765885  Lpar5; lysophosphatidic acid receptor 5 isoform X2 [KO:K08390]
100750873  Lpar6; lysophosphatidic acid receptor 6 [KO:K04273]
100755233  type-1A angiotensin II receptor [KO:K04166]
100750798  Agtr1; type-1 angiotensin II receptor [KO:K04166]
100760944  Gna12; guanine nucleotide-binding protein subunit alpha-12 isoform X3 [KO:K04346]
100689071  Gna13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
100765006  Arhgef12; rho guanine nucleotide exchange factor 12 isoform X3 [KO:K07532]
100760875  Arhgef11; rho guanine nucleotide exchange factor 11 isoform X12 [KO:K12331]
100758784  Arhgef1; rho guanine nucleotide exchange factor 1 isoform X2 [KO:K12330]
100755823  pleckstrin homology domain-containing family G member 5 isoform X2 [KO:K19464]
100762797  Rhoa; transforming protein RhoA [KO:K04513]
100757042  transforming protein RhoA isoform X1 [KO:K04513]
100770074  Rock1; rho-associated protein kinase 1 isoform X3 [KO:K04514] [EC:2.7.11.1]
100767265  Rock2; rho-associated protein kinase 2 isoform X2 [KO:K17388] [EC:2.7.11.1]
100759082  Cxcl12; stromal cell-derived factor 1 isoform X2 [KO:K10031]
100767733  Cxcr4; C-X-C chemokine receptor type 4 isoform X1 [KO:K04189]
100689068  Gnai2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
100689072  Gnai3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
100689070  Gnai1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
100753028  Ptger1; prostaglandin E2 receptor EP1 subtype isoform X2 [KO:K04258]
100774710  Ptger2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
100752421  Ptger3; prostaglandin E2 receptor EP3 subtype isoform X2 [KO:K04260]
100769862  Ptger4; prostaglandin E2 receptor EP4 subtype isoform X2 [KO:K04261]
100689067  Gnas; guanine nucleotide-binding protein G(s) subunit alpha [KO:K04632]
103158534  neuroendocrine secretory protein 55 [KO:K04632]
100764561  Adcy1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
100773811  Adcy2; adenylate cyclase type 2 isoform X2 [KO:K08042] [EC:4.6.1.1]
100770498  Adcy3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
100768998  Adcy4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
100765958  Adcy5; LOW QUALITY PROTEIN: adenylate cyclase type 5 isoform X2 [KO:K08045] [EC:4.6.1.1]
100768368  Adcy6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
100756132  Adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
113837458  adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
100751372  Adcy9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
100768997  Prkaca; cAMP-dependent protein kinase catalytic subunit alpha isoform X2 [KO:K04345] [EC:2.7.11.11]
100767097  Prkacb; cAMP-dependent protein kinase catalytic subunit beta isoform X2 [KO:K04345] [EC:2.7.11.11]
100689442  Gnb1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
100756281  Gnb2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X2 [KO:K04537]
100756790  Gnb3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1 [KO:K07825]
100757050  Gnb4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
100764899  Gnb5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
100768753  Gng2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
100755128  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
100769650  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
118238929  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2-like [KO:K07826]
100755432  Gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
100767992  Gng4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
100757206  Gng5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
103162614  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
100752390  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
103163959  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
113832276  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
100765832  Gng7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
113837383  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
100755995  Gng10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 isoform X2 [KO:K04545]
100761038  Gng11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
100757536  Gng12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
107978884  Gng14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
100774382  Gng13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
100760746  Gngt1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
100754408  Gngt2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
107976999  Col4a2; collagen alpha-2(IV) chain isoform X2 [KO:K06237]
100757740  Col4a1; collagen alpha-1(IV) chain isoform X4 [KO:K06237]
103158667  Col4a3; collagen alpha-3(IV) chain isoform X2 [KO:K06237]
100772869  collagen alpha-6(IV) chain isoform X3 [KO:K06237]
100772575  collagen alpha-5(IV) chain isoform X2 [KO:K06237]
100756006  collagen alpha-4(IV) chain isoform X2 [KO:K06237]
100771923  laminin subunit alpha-2 isoform X3 [KO:K05637]
100765555  Lama1; laminin subunit alpha-1 isoform X2 [KO:K05637]
100755004  Lama3; laminin subunit alpha-3 isoform X3 [KO:K06240]
100755091  Lama5; laminin subunit alpha-5 [KO:K06240]
100757321  Lama4; laminin subunit alpha-4 isoform X1 [KO:K06241]
100757343  Lamb1; laminin subunit beta-1 isoform X1 [KO:K05636]
100762566  Lamb2; laminin subunit beta-2 isoform X1 [KO:K06243]
100763082  Lamb3; laminin subunit beta-3 [KO:K06244]
100761564  Lamc1; laminin subunit gamma-1 isoform X2 [KO:K05635]
100765048  Lamc2; laminin subunit gamma-2 isoform X2 [KO:K06246]
100751974  Lamc3; laminin subunit gamma-3 isoform X2 [KO:K06247]
100751189  Fn1; fibronectin isoform X1 [KO:K05717]
100774579  Itga2; integrin alpha-2 isoform X2 [KO:K06481]
100762814  Itga2b; integrin alpha-IIb isoform X2 [KO:K06476]
100758471  Itga3; integrin alpha-3 isoform X1 [KO:K06482]
100769534  Itga6; integrin alpha-6 isoform X1 [KO:K06485]
100752313  Itgav; integrin alpha-V isoform X2 [KO:K06487]
100763033  Itgb1; integrin beta-1 isoform X2 [KO:K05719]
100759464  Ptk2; focal adhesion kinase 1 isoform X5 [KO:K05725] [EC:2.7.10.2]
100689251  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100769225  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X2 [KO:K00922] [EC:2.7.1.153]
100689252  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2 [KO:K00922] [EC:2.7.1.153]
100771181  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X2 [KO:K02649]
100750761  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
100774067  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
100764294  Pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
100752275  Nkx3-1; homeobox protein Nkx-3.1 isoform X2 [KO:K09348]
100768351  Akt2; RAC-beta serine/threonine-protein kinase isoform X2 [KO:K04456] [EC:2.7.11.1]
100752454  Akt3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100769460  Akt1; RAC-alpha serine/threonine-protein kinase isoform X2 [KO:K04456] [EC:2.7.11.1]
100754432  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X5 [KO:K04467] [EC:2.7.11.10]
100750488  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
100759762  Ikbkg; NF-kappa-B essential modulator isoform X6 [KO:K07210]
100754153  Nfkbia; NF-kappa-B inhibitor alpha isoform X2 [KO:K04734]
100770607  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X3 [KO:K02580]
100774604  Nfkb2; nuclear factor NF-kappa-B p100 subunit isoform X2 [KO:K04469]
100763542  Rela; transcription factor p65 isoform X4 [KO:K04735]
100751220  Ptgs2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
100760062  Nos2; nitric oxide synthase, inducible isoform X2 [KO:K13241] [EC:1.14.13.39]
100774873  Bcl2; apoptosis regulator Bcl-2 isoform X3 [KO:K02161]
100756596  Birc2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
100761700  baculoviral IAP repeat-containing protein 3 isoform X2 [KO:K16060]
100689374  Xiap; baculoviral IAP repeat-containing protein 4 [KO:K04725] [EC:2.3.2.27]
100758467  Birc7; baculoviral IAP repeat-containing protein 7 [KO:K16061]
100689371  Bcl2l1; bcl-2-like protein 1 [KO:K04570]
100756802  Traf1; TNF receptor-associated factor 1 isoform X2 [KO:K03172]
100762099  Traf2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
100756323  Traf3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
100762863  Traf4; TNF receptor-associated factor 4 isoform X2 [KO:K09848]
100760758  Traf5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
100753700  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
100755421  Mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
100757513  Rps6kb1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
100760227  Rps6kb2; ribosomal protein S6 kinase beta-2 [KO:K04688] [EC:2.7.11.1]
100760426  Bad; bcl2-associated agonist of cell death isoform X2 [KO:K02158]
100768647  Foxo1; forkhead box protein O1 isoform X2 [KO:K07201]
100770120  Mdm2; E3 ubiquitin-protein ligase Mdm2 isoform X3 [KO:K06643] [EC:2.3.2.27]
100682525  Tp53; cellular tumor antigen p53 [KO:K04451]
100689401  Cdkn1b; cyclin-dependent kinase inhibitor 1B [KO:K06624]
103160601  Cdkn1a; cyclin-dependent kinase inhibitor 1 isoform X2 [KO:K06625]
100768252  Bcr; breakpoint cluster region protein isoform X2 [KO:K08878] [EC:2.7.11.1]
100768098  Abl1; tyrosine-protein kinase ABL1 isoform X2 [KO:K06619] [EC:2.7.10.2]
100752014  Crkl; crk-like protein isoform X1 [KO:K04438]
100762827  Crk; adapter molecule crk isoform X2 [KO:K04438]
100754737  Cbl; E3 ubiquitin-protein ligase CBL isoform X2 [KO:K04707] [EC:2.3.2.27]
100755571  signal transducer and activator of transcription 5A isoform X1 [KO:K11223]
100750571  signal transducer and activator of transcription 5B isoform X2 [KO:K11224]
100751275  Pim1; serine/threonine-protein kinase pim-1 isoform X2 [KO:K04702] [EC:2.7.11.1]
100762236  Pim2; serine/threonine-protein kinase pim-2 [KO:K08806] [EC:2.7.11.1]
100764285  Kng1; kininogen-1 isoform X1 [KO:K03898]
100768493  Edn1; endothelin-1 [KO:K16366]
100759905  Bdkrb1; B1 bradykinin receptor [KO:K03915]
100759615  Bdkrb2; B2 bradykinin receptor [KO:K03916]
100774176  Ednra; endothelin-1 receptor isoform X1 [KO:K04197]
100762726  Ednrb; endothelin receptor type B [KO:K04198]
100689066  Gnaq; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
100689065  Gna11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
100760134  Plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X2 [KO:K05858] [EC:3.1.4.11]
100760731  Plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
100770957  Plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
100751979  Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2 [KO:K05858] [EC:3.1.4.11]
100766006  Prkca; protein kinase C alpha type isoform X2 [KO:K02677] [EC:2.7.11.13]
100760922  Prkcb; protein kinase C beta type isoform X2 [KO:K19662] [EC:2.7.11.13]
100762950  Prkcg; protein kinase C gamma type isoform X2 [KO:K19663] [EC:2.7.11.13]
100755773  Il2; interleukin-2 [KO:K05429]
100755642  Il4; interleukin-4 [KO:K05430]
100755060  Il5; interleukin-5 [KO:K05428]
100689186  Il6; interleukin-6 [KO:K05405]
100756443  Il7; interleukin-7 isoform X1 [KO:K05431]
100760602  Il12a; interleukin-12 subunit alpha [KO:K05406]
100764758  Il12b; interleukin-12 subunit beta [KO:K05425]
100762597  Il13; interleukin-13 [KO:K05435]
100772160  Il15; interleukin-15 isoform X1 [KO:K05433]
100765061  Il23a; interleukin-23 subunit alpha [KO:K05426]
100753960  Epo; erythropoietin isoform X1 [KO:K05437]
100760028  interferon alpha-12 [KO:K05414]
100760616  interferon alpha-9 isoform X2 [KO:K05414]
100760323  interferon alpha-12 [KO:K05414]
100762064  interferon alpha-12 [KO:K05414]
100762655  interferon alpha-9 [KO:K05414]
100763520  interferon alpha-3 [KO:K05414]
100765269  interferon alpha-9 [KO:K05414]
100765849  interferon alpha-12 [KO:K05414]
100766144  interferon alpha-12 [KO:K05414]
100766726  interferon alpha-12 [KO:K05414]
100759741  interferon alpha-12 [KO:K05414]
100750635  interferon alpha-12 [KO:K05414]
100750928  interferon alpha-2-like [KO:K05414]
100751221  interferon alpha-12 [KO:K05414]
100769352  interferon alpha-12 [KO:K05414]
100769640  interferon alpha-9 [KO:K05414]
100768486  Ifng; interferon gamma isoform X2 [KO:K04687]
100764797  Il2ra; interleukin-2 receptor subunit alpha [KO:K05068]
113832088  interleukin-2 receptor subunit beta-like isoform X2 [KO:K05069]
100756284  Il2rg; cytokine receptor common subunit gamma [KO:K05070]
113838537  interleukin-3 receptor subunit alpha-like [KO:K04737]
100762840  Il4r; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
113831896  cytokine receptor common subunit beta isoform X1 [KO:K04738]
100764512  Csf2rb; cytokine receptor common subunit beta isoform X2 [KO:K04738]
100762117  Il5ra; interleukin-5 receptor subunit alpha [KO:K05067]
100750971  Il6r; interleukin-6 receptor subunit alpha isoform X3 [KO:K05055]
100767181  Il6st; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
100757700  Il7r; interleukin-7 receptor subunit alpha [KO:K05072]
100763378  Il12rb1; interleukin-12 receptor subunit beta-1 isoform X3 [KO:K05063]
100758602  Il12rb2; interleukin-12 receptor subunit beta-2 isoform X1 [KO:K05064]
100771375  Il13ra1; interleukin-13 receptor subunit alpha-1 isoform X2 [KO:K05076]
100755321  Il15ra; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
100758310  Il23r; interleukin-23 receptor [KO:K05065]
100769376  Epor; erythropoietin receptor isoform X2 [KO:K05079]
100768581  Ifnar1; interferon alpha/beta receptor 1 isoform X2 [KO:K05130]
100768006  interferon alpha/beta receptor 2 isoform X4 [KO:K05131]
100772793  Ifngr1; interferon gamma receptor 1 [KO:K05132]
100768877  Ifngr2; interferon gamma receptor 2 isoform X3 [KO:K05133]
100764725  Eml4; echinoderm microtubule-associated protein-like 4 isoform X3 [KO:K15420]
100760366  Alk; ALK tyrosine kinase receptor isoform X2 [KO:K05119] [EC:2.7.10.1]
100762037  Rasgrp1; RAS guanyl-releasing protein 1 isoform X2 [KO:K04350]
100757059  Rasgrp2; RAS guanyl-releasing protein 2 [KO:K12361]
100764463  Rasgrp3; ras guanyl-releasing protein 3 isoform X2 [KO:K12362]
100765723  Rasgrp4; RAS guanyl-releasing protein 4 isoform X2 [KO:K12363]
100754824  Jak1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
100769337  Jak2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
100773497  Jak3; tyrosine-protein kinase JAK3 isoform X2 [KO:K11218] [EC:2.7.10.2]
100755865  Stat3; signal transducer and activator of transcription 3 isoform X9 [KO:K04692]
100755609  Stat1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
100764772  Stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
100769249  signal transducer and activator of transcription 4 isoform X3 [KO:K11222]
100753838  Stat6; signal transducer and activator of transcription 6 isoform X1 [KO:K11225]
100755957  Vegfa; LOW QUALITY PROTEIN: vascular endothelial growth factor A isoform X2 [KO:K05448]
100759545  Vegfb; vascular endothelial growth factor B isoform X2 [KO:K16858]
100754799  Pgf; placenta growth factor [KO:K16859]
100773421  Vegfd; vascular endothelial growth factor D isoform X1 [KO:K05449]
100753419  Vegfc; vascular endothelial growth factor C isoform X1 [KO:K05449]
100754730  Tgfa; LOW QUALITY PROTEIN: protransforming growth factor alpha isoform X2 [KO:K08774]
100763146  Egf; pro-epidermal growth factor isoform X2 [KO:K04357]
100774580  Egfr; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
100759983  Erbb2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
100771503  Pdgfa; platelet-derived growth factor subunit A isoform X2 [KO:K04359]
100774990  Pdgfb; platelet-derived growth factor subunit B isoform X2 [KO:K17386]
100760258  Pdgfra; platelet-derived growth factor receptor alpha precursor [KO:K04363] [EC:2.7.10.1]
100764374  Pdgfrb; platelet-derived growth factor receptor beta isoform X2 [KO:K05089] [EC:2.7.10.1]
100751642  Igf1; insulin-like growth factor I isoform X1 [KO:K05459]
100762359  Igf2; LOW QUALITY PROTEIN: insulin-like growth factor II isoform X2 [KO:K13769]
100768531  Igf1r; insulin-like growth factor 1 receptor isoform X2 [KO:K05087] [EC:2.7.10.1]
100752139  Kitlg; kit ligand isoform X1 [KO:K05461]
100751027  Kit; mast/stem cell growth factor receptor Kit isoform X3 [KO:K05091] [EC:2.7.10.1]
100773162  Flt3lg; fms-related tyrosine kinase 3 ligand isoform X1 [KO:K05454]
100761902  Flt3; receptor-type tyrosine-protein kinase FLT3 isoform X2 [KO:K05092] [EC:2.7.10.1]
100764472  Hgf; hepatocyte growth factor isoform X1 [KO:K05460]
100751933  Met; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
100764257  Fgf1; fibroblast growth factor 1 isoform X1 [KO:K18496]
100757429  Fgf2; fibroblast growth factor 2 isoform X2 [KO:K18497]
100764611  Fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
100772115  Fgf6; fibroblast growth factor 6 [KO:K04358]
103160353  Fgf22; fibroblast growth factor 22 isoform X2 [KO:K04358]
100758023  Fgf4; fibroblast growth factor 4 isoform X2 [KO:K04358]
100773578  Fgf20; fibroblast growth factor 20 [KO:K04358]
100759509  Fgf9; fibroblast growth factor 9 [KO:K04358]
100761599  Fgf7; fibroblast growth factor 7 [KO:K04358]
100750999  Fgf8; fibroblast growth factor 8 isoform X2 [KO:K04358]
100757734  Fgf3; fibroblast growth factor 3 isoform X2 [KO:K04358]
100751051  Fgf10; fibroblast growth factor 10 [KO:K04358]
100767099  Fgf16; fibroblast growth factor 16 isoform X2 [KO:K04358]
100763237  Fgf5; fibroblast growth factor 5 [KO:K04358]
100761504  fibroblast growth factor 18 isoform X2 [KO:K04358]
100758307  Fgf19; fibroblast growth factor 19 isoform X2 [KO:K22603]
100757339  Fgf21; fibroblast growth factor 21 [KO:K22429]
100763837  Fgf23; fibroblast growth factor 23 [KO:K22428]
100773586  Fgfr1; fibroblast growth factor receptor 1 isoform X1 [KO:K04362] [EC:2.7.10.1]
100763455  Fgfr2; fibroblast growth factor receptor 2 isoform X4 [KO:K05093] [EC:2.7.10.1]
100764560  Fgfr3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
100765320  Fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
100769627  Grb2; growth factor receptor-bound protein 2 isoform X1 [KO:K04364]
100757521  Sos1; son of sevenless homolog 1 isoform X2 [KO:K03099]
100769325  Sos2; son of sevenless homolog 2 isoform X3 [KO:K03099]
100773737  Hras; GTPase HRas isoform X2 [KO:K02833]
100763178  Kras; GTPase KRas isoform X4 [KO:K07827]
113839127  GTPase KRas-like [KO:K07827]
113837935  GTPase KRas-like isoform X2 [KO:K07827]
113837956  GTPase KRas-like [KO:K07827]
113838653  GTPase KRas-like isoform X2 [KO:K07827]
113838692  GTPase KRas-like [KO:K07827]
113838722  GTPase KRas-like isoform X1 [KO:K07827]
113838818  GTPase KRas-like [KO:K07827]
113837633  GTPase KRas-like isoform X1 [KO:K07827]
113838146  GTPase KRas-like isoform X1 [KO:K07827]
113838876  GTPase KRas-like [KO:K07827]
113838228  GTPase KRas-like isoform X1 [KO:K07827]
113839011  GTPase KRas-like [KO:K07827]
100771078  GTPase KRas-like isoform X2 [KO:K07827]
113837960  GTPase KRas-like [KO:K07827]
113838098  GTPase KRas-like [KO:K07827]
113838326  GTPase KRas-like [KO:K07827]
113838417  GTPase KRas-like isoform X1 [KO:K07827]
113838488  GTPase KRas-like [KO:K07827]
113838583  GTPase KRas-like isoform X1 [KO:K07827]
113838676  GTPase KRas-like [KO:K07827]
113838679  GTPase KRas-like isoform X1 [KO:K07827]
113838746  GTPase KRas-like [KO:K07827]
113838796  GTPase KRas-like isoform X1 [KO:K07827]
113838871  GTPase KRas-like [KO:K07827]
113838872  GTPase KRas-like [KO:K07827]
113838892  GTPase KRas-like [KO:K07827]
113838898  GTPase KRas-like [KO:K07827]
113838914  GTPase KRas-like [KO:K07827]
113838921  GTPase KRas-like [KO:K07827]
113838942  GTPase KRas-like isoform X1 [KO:K07827]
113838943  GTPase KRas-like isoform X1 [KO:K07827]
113839007  GTPase HRas-like isoform X1 [KO:K07827]
118239746  GTPase KRas-like isoform X1 [KO:K07827]
118239767  GTPase KRas-like isoform X1 [KO:K07827]
118239768  GTPase KRas-like [KO:K07827]
118239770  GTPase KRas-like [KO:K07827]
118239801  GTPase KRas-like [KO:K07827]
118239825  GTPase KRas-like isoform X1 [KO:K07827]
100757614  Nras; GTPase NRas [KO:K07828]
100751432  Araf; serine/threonine-protein kinase A-Raf isoform X5 [KO:K08845] [EC:2.7.11.1]
100771486  Braf; LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf isoform X6 [KO:K04365] [EC:2.7.11.1]
100769018  Raf1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
100689403  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
113835540  dual specificity mitogen-activated protein kinase kinase 1-like isoform X1 [KO:K04368] [EC:2.7.12.2]
103158537  dual specificity mitogen-activated protein kinase kinase 1-like isoform X2 [KO:K04368] [EC:2.7.12.2]
100774204  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 isoform X2 [KO:K04369] [EC:2.7.12.2]
100759514  Mapk1; mitogen-activated protein kinase 1 isoform X2 [KO:K04371] [EC:2.7.11.24]
100753149  Mapk3; mitogen-activated protein kinase 3 isoform X2 [KO:K04371] [EC:2.7.11.24]
113834001  transcription factor AP-1 [KO:K04448]
100689418  Fos; proto-oncogene c-Fos [KO:K04379]
100767456  Ets1; protein C-ets-1 isoform X2 [KO:K02678]
100754854  interstitial collagenase A [KO:K01388] [EC:3.4.24.7]
100774744  Mmp2; 72 kDa type IV collagenase [KO:K01398] [EC:3.4.24.24]
100770707  Mmp9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
100760122  Cdk4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
100753249  Rps6ka5; ribosomal protein S6 kinase alpha-5 isoform X4 [KO:K04445] [EC:2.7.11.1]
100772741  Ret; proto-oncogene tyrosine-protein kinase receptor Ret isoform X2 [KO:K05126] [EC:2.7.10.1]
100761094  Ccdc6; coiled-coil domain-containing protein 6 isoform X2 [KO:K09288]
100756488  Ncoa4; nuclear receptor coactivator 4 [KO:K09289]
100751271  Ntrk1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
100763482  Tpm3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
103164511  tropomyosin alpha-3 chain isoform X2 [KO:K09290]
113833120  tropomyosin alpha-3 chain-like isoform X2 [KO:K09290]
100753776  Tpr; nucleoprotein TPR isoform X2 [KO:K09291]
100757801  Tfg; protein TFG isoform X5 [KO:K09292]
100769756  ras association domain-containing protein 1 isoform X2 [KO:K09850]
100758747  Rassf5; ras association domain-containing protein 5 isoform X3 [KO:K08015]
100757702  Stk4; serine/threonine-protein kinase 4 isoform X1 [KO:K04411]
100773624  Dapk3; death-associated protein kinase 3 isoform X5 [KO:K08803] [EC:2.7.11.1]
100766355  Dapk1; death-associated protein kinase 1 isoform X2 [KO:K08803] [EC:2.7.11.1]
100773012  Dapk2; death-associated protein kinase 2 [KO:K08803] [EC:2.7.11.1]
100769697  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2 [KO:K01116] [EC:3.1.4.11]
100752475  Plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
100763890  Elk1; ETS domain-containing protein Elk-1 [KO:K04375]
100766751  Calml3; calmodulin-like protein 3 [KO:K02183]
100767046  Calml5; calmodulin-like protein 5 isoform X1 [KO:K02183]
100762749  Calm3; calmodulin-3 isoform X2 [KO:K02183]
100765281  Calm2; calmodulin-2 isoform X2 [KO:K02183]
100771772  Calm1; calmodulin-1 isoform X2 [KO:K02183]
100757500  Calml4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
100751814  calmodulin-like isoform X2 [KO:K02183]
100769205  Camk2b; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X2 [KO:K04515] [EC:2.7.11.17]
100763272  Camk2g; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X2 [KO:K04515] [EC:2.7.11.17]
100752268  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4 [KO:K04515] [EC:2.7.11.17]
100765253  Camk2a; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X3 [KO:K04515] [EC:2.7.11.17]
100771841  Ralgds; ral guanine nucleotide dissociation stimulator isoform X2 [KO:K08732]
100769632  Rala; ras-related protein Ral-A [KO:K07834]
100769446  LOW QUALITY PROTEIN: ras-related protein Ral-A-like [KO:K07834]
100757867  Ralb; ras-related protein Ral-B [KO:K07835]
100756078  Ralbp1; ralA-binding protein 1 [KO:K08773]
100765433  Cdc42; cell division control protein 42 homolog [KO:K04393]
100756792  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
113837706  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
100767225  ras-related C3 botulinum toxin substrate 2 isoform X2 [KO:K07860]
100757479  Rac3; ras-related C3 botulinum toxin substrate 3 isoform X2 [KO:K07861]
100752582  Pld2; phospholipase D2 isoform X4 [KO:K01115] [EC:3.1.4.4]
100689404  Pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
100771734  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
100754361  mitogen-activated protein kinase 10 isoform X5 [KO:K04440] [EC:2.7.11.24]
100764964  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
100758326  Pax8; paired box protein Pax-8 isoform X2 [KO:K09293]
100689245  Pparg; peroxisome proliferator-activated receptor gamma [KO:K08530]
100768377  Rxra; retinoic acid receptor RXR-alpha isoform X2 [KO:K08524]
100759059  Rxrb; LOW QUALITY PROTEIN: retinoic acid receptor RXR-beta isoform X2 [KO:K08525]
100759819  Rxrg; retinoic acid receptor RXR-gamma [KO:K08526]
100768698  Rarb; retinoic acid receptor beta isoform X2 [KO:K08528]
100768474  Esr1; estrogen receptor isoform X2 [KO:K08550]
100763291  Esr2; estrogen receptor beta isoform X2 [KO:K08551]
100755152  Ncoa1; nuclear receptor coactivator 1 isoform X1 [KO:K09101] [EC:2.3.1.48]
100774568  Ncoa3; nuclear receptor coactivator 3 isoform X1 [KO:K11256] [EC:2.3.1.48]
100767199  Sp1; transcription factor Sp1 isoform X3 [KO:K04684]
100755002  Ppard; peroxisome proliferator-activated receptor delta [KO:K04504]
100760007  Jup; junction plakoglobin [KO:K10056]
100769421  Zbtb16; zinc finger and BTB domain-containing protein 16 isoform X2 [KO:K10055]
100771910  Rara; retinoic acid receptor alpha isoform X1 [KO:K08527]
100759649  Ccna2; cyclin-A2 isoform X2 [KO:K06627]
100769969  Ccna1; cyclin-A1 isoform X2 [KO:K06627]
100757598  Pml; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
100758283  Runx1; runt-related transcription factor 1 isoform X5 [KO:K08367]
100768348  Runx1t1; LOW QUALITY PROTEIN: protein CBFA2T1 isoform X2 [KO:K10053]
100763362  Spi1; transcription factor PU.1 isoform X4 [KO:K09438]
113837181  CCAAT/enhancer-binding protein alpha [KO:K09055]
113833669  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like [KO:K05066]
100760185  Csf3r; granulocyte colony-stimulating factor receptor [KO:K05061]
100763221  Csf1r; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
100764983  tumor suppressor ARF isoform X2 [KO:K06621]
100758556  E2f1; LOW QUALITY PROTEIN: transcription factor E2F1 isoform X2 [KO:K17454]
100754522  E2f2; transcription factor E2F2 isoform X2 [KO:K09389]
100754647  E2f3; transcription factor E2F3 isoform X1 [KO:K06620]
100752515  Max; protein max isoform X2 [KO:K04453]
100754046  Zbtb17; zinc finger and BTB domain-containing protein 17 isoform X2 [KO:K10500]
113833995  cyclin-dependent kinase 4 inhibitor B [KO:K04685]
100764515  Cdk6; cyclin-dependent kinase 6 isoform X2 [KO:K02091] [EC:2.7.11.22]
100771544  Ccnd2; G1/S-specific cyclin-D2 [KO:K10151]
100766025  Ccnd3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
100760892  cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
100760104  Cks2; cyclin-dependent kinases regulatory subunit 2 isoform X2 [KO:K02219]
100771339  LOW QUALITY PROTEIN: cyclin-dependent kinases regulatory subunit 2-like [KO:K02219]
118237705  cyclin-dependent kinases regulatory subunit 1 isoform X2 [KO:K02219]
100757677  Skp1; S-phase kinase-associated protein 1 [KO:K03094]
100757763  Cul1; cullin-1 [KO:K03347]
100762556  Rbx1; E3 ubiquitin-protein ligase RBX1 [KO:K03868] [EC:2.3.2.32]
100771396  Skp2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
100689039  Cdk2; cyclin-dependent kinase 2 [KO:K02206] [EC:2.7.11.22]
100760464  Ccne2; G1/S-specific cyclin-E2 isoform X3 [KO:K06626]
100753358  Ccne1; G1/S-specific cyclin-E1 isoform X2 [KO:K06626]
100752928  Rb1; LOW QUALITY PROTEIN: retinoblastoma-associated protein isoform X2 [KO:K06618]
103159266  Gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha isoform X2 [KO:K04402]
100759228  Gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
100766127  Gadd45b; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
100689032  Bax; apoptosis regulator BAX [KO:K02159]
100689368  Bak1; bcl-2 homologous antagonist/killer [KO:K14021]
100756705  Ddb2; LOW QUALITY PROTEIN: DNA damage-binding protein 2 [KO:K10140]
100758099  Polk; DNA polymerase kappa isoform X3 [KO:K03511] [EC:2.7.7.7]
100774541  Tert; telomerase reverse transcriptase isoform X4 [KO:K11126] [EC:2.7.7.49]
100754846  Mitf; microphthalmia-associated transcription factor isoform X1 [KO:K09455]
100773359  Tgfb1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
100774918  Tgfb2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
100756831  Tgfb3; transforming growth factor beta-3 proprotein isoform X1 [KO:K13377]
100772727  Tgfbr1; TGF-beta receptor type-1 isoform X3 [KO:K04674] [EC:2.7.11.30]
100773953  Tgfbr2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
100771578  Smad2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
100759220  Smad3; mothers against decapentaplegic homolog 3 isoform X3 [KO:K23605]
100770737  Smad4; mothers against decapentaplegic homolog 4 isoform X2 [KO:K04501]
100768628  Mecom; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
100769412  Ctbp2; C-terminal-binding protein 2 isoform X1 [KO:K04496] [EC:1.1.1.428]
100766703  Ctbp1; C-terminal-binding protein 1 isoform X4 [KO:K04496] [EC:1.1.1.428]
100762805  LOW QUALITY PROTEIN: C-terminal-binding protein 2-like [KO:K04496] [EC:1.1.1.428]
100764557  Hdac2; histone deacetylase 2 isoform X2 [KO:K06067] [EC:3.5.1.98]
100752721  Hdac1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
100761556  histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
100769879  Mlh1; DNA mismatch repair protein Mlh1 isoform X1 [KO:K08734]
100768127  Msh2; DNA mismatch repair protein Msh2 isoform X2 [KO:K08735]
100762943  Msh3; DNA mismatch repair protein Msh3 isoform X3 [KO:K08736]
100771087  Msh6; DNA mismatch repair protein Msh6 isoform X2 [KO:K08737]
100689197  Brca2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein isoform X7 [KO:K08775]
100689324  Rad51; DNA repair protein RAD51 homolog 1 [KO:K04482]
100773293  Faslg; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
100762537  Fas; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
100774599  Fadd; FAS-associated death domain protein isoform X1 [KO:K02373]
100689369  Casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
100754606  Bid; BH3-interacting domain death agonist [KO:K04726]
100755393  Pmaip1; phorbol-12-myristate-13-acetate-induced protein 1 isoform X2 [KO:K10131]
103164214  Bbc3; bcl-2-binding component 3 isoform X2 [KO:K10132]
100771754  Bcl2l11; bcl-2-like protein 11 isoform X2 [KO:K16341]
107977792  cytochrome c-like [KO:K08738]
103160806  cytochrome c-like [KO:K08738]
100757098  cytochrome c, somatic [KO:K08738]
100764460  cytochrome c, testis-specific [KO:K08738]
100773626  cytochrome c, somatic [KO:K08738]
100754043  cytochrome c, somatic [KO:K08738]
100768478  cytochrome c [KO:K08738]
103164112  cytochrome c-like [KO:K08738]
100751857  cytochrome c, somatic-like [KO:K08738]
100758500  apoptotic protease-activating factor 1 isoform X4 [KO:K02084]
100766857  Casp7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
100759410  Keap1; kelch-like ECH-associated protein 1 isoform X1 [KO:K10456]
100752102  Nfe2l2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638]
100756872  Hmox1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
100760905  Nqo1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
100754357  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
100753172  glutathione S-transferase alpha-5 [KO:K00799] [EC:2.5.1.18]
100753467  glutathione S-transferase alpha-3 isoform X1 [KO:K00799] [EC:2.5.1.18]
100753770  glutathione S-transferase A6 isoform X2 [KO:K00799] [EC:2.5.1.18]
100757858  glutathione S-transferase Mu 1 [KO:K00799] [EC:2.5.1.18]
100768110  glutathione S-transferase Mu 6 isoform X1 [KO:K00799] [EC:2.5.1.18]
100766772  glutathione S-transferase Y1 isoform X2 [KO:K00799] [EC:2.5.1.18]
100767530  glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
100750644  glutathione S-transferase Mu 7 [KO:K00799] [EC:2.5.1.18]
100750357  Gstm3; glutathione S-transferase Mu 3 [KO:K00799] [EC:2.5.1.18]
100758427  Gsto1; glutathione S-transferase omega-1 isoform X5 [KO:K00799] [EC:2.5.1.18]
100753857  glutathione S-transferase A2 isoform X2 [KO:K00799] [EC:2.5.1.18]
100759107  glutathione S-transferase omega-2 isoform X2 [KO:K00799] [EC:2.5.1.18]
100750937  glutathione S-transferase Mu 2 isoform X2 [KO:K00799] [EC:2.5.1.18]
100768553  glutathione S-transferase theta-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
100752137  glutathione S-transferase A2 isoform X1 [KO:K00799] [EC:2.5.1.18]
100753254  glutathione S-transferase A4 [KO:K00799] [EC:2.5.1.18]
100774867  Mgst1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
100759236  Mgst3; microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
100766034  glutathione S-transferase theta-2 [KO:K00799] [EC:2.5.1.18]
100765453  glutathione S-transferase theta-3 [KO:K00799] [EC:2.5.1.18]
100764249  Mgst2; microsomal glutathione S-transferase 2 [KO:K00799] [EC:2.5.1.18]
100765742  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
113835189  glutathione S-transferase A2-like isoform X2 [KO:K00799] [EC:2.5.1.18]
113835190  glutathione S-transferase A2-like [KO:K00799] [EC:2.5.1.18]
100767818  glutathione S-transferase Mu 3 isoform X1 [KO:K00799] [EC:2.5.1.18]
100689311  Gstp1; glutathione S-transferase P 1 [KO:K23790] [EC:2.5.1.18]
100757534  glutathione S-transferase P 2 isoform X1 [KO:K23790] [EC:2.5.1.18]
100771594  Txnrd1; thioredoxin reductase 1, cytoplasmic [KO:K22182] [EC:1.8.1.9]
100770343  Txnrd2; thioredoxin reductase 2, mitochondrial isoform X7 [KO:K22182] [EC:1.8.1.9]
100770105  Txnrd3; thioredoxin reductase 3 isoform X2 [KO:K22182] [EC:1.8.1.9]
100751916  Vhl; von Hippel-Lindau disease tumor suppressor isoform X2 [KO:K03871]
100757872  Eloc; elongin-C [KO:K03872]
100750378  elongin-C-like [KO:K03872]
100757582  elongin-C-like [KO:K03872]
100765126  elongin-C-like [KO:K03872]
100766274  elongin-C-like [KO:K03872]
100758808  elongin-B [KO:K03873]
100772696  Elob; elongin-B isoform X2 [KO:K03873]
113833831  elongin-B-like [KO:K03873]
113833885  elongin-B-like [KO:K03873]
113834552  elongin-B-like [KO:K03873]
100767582  Cul2; cullin-2 [KO:K03870]
100754377  Egln3; prolyl hydroxylase EGLN3 isoform X2 [KO:K09592] [EC:1.14.11.29]
100771495  Egln2; prolyl hydroxylase EGLN2 isoform X2 [KO:K09592] [EC:1.14.11.29]
100772704  Egln1; egl nine homolog 1 isoform X2 [KO:K09592] [EC:1.14.11.29]
100773218  Fh; fumarate hydratase, mitochondrial isoform X1 [KO:K01679] [EC:4.2.1.2]
100751293  Hif1a; hypoxia-inducible factor 1-alpha isoform X3 [KO:K08268]
100771160  Epas1; endothelial PAS domain-containing protein 1 isoform X2 [KO:K09095]
100752106  Arnt; aryl hydrocarbon receptor nuclear translocator isoform X8 [KO:K09097]
100773566  Arnt2; aryl hydrocarbon receptor nuclear translocator 2 isoform X2 [KO:K15589]
100762260  Ep300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
100770451  histone lysine acetyltransferase CREBBP isoform X3 [KO:K04498] [EC:2.3.1.48]
100753506  Slc2a1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
100750525  Jag1; protein jagged-1 isoform X3 [KO:K06052]
100753300  Jag2; protein jagged-2 isoform X2 [KO:K21635]
100750697  Dll1; delta-like protein 1 [KO:K06051]
100763048  Dll4; delta-like protein 4 isoform X2 [KO:K06051]
100773804  Dll3; delta-like protein 3 isoform X2 [KO:K06051]
100761880  Notch1; neurogenic locus notch homolog protein 1 isoform X2 [KO:K02599]
100771788  Notch2; neurogenic locus notch homolog protein 2 isoform X2 [KO:K20994]
100753340  Notch3; neurogenic locus notch homolog protein 3 isoform X3 [KO:K20995]
100765940  Notch4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4 isoform X2 [KO:K20996]
100752756  Hes1; transcription factor HES-1 isoform X2 [KO:K06054]
113833739  transcription factor HES-5 [KO:K06055]
100752534  Hey1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X3 [KO:K09091]
100771786  Heyl; hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091]
100755611  Hey2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X2 [KO:K09091]
100766609  Flt4; vascular endothelial growth factor receptor 3 isoform X2 [KO:K05097] [EC:2.7.10.1]
100773402  Shh; sonic hedgehog protein isoform X2 [KO:K11988]
100763926  Ptch1; protein patched homolog 1 isoform X3 [KO:K06225]
100762005  Smo; smoothened homolog isoform X2 [KO:K06226]
100762172  Kif7; kinesin-like protein KIF7 isoform X2 [KO:K18806]
100753058  Sufu; suppressor of fused homolog isoform X4 [KO:K06229]
100763229  Gli1; zinc finger protein GLI1 isoform X1 [KO:K16797]
100757572  Gli2; zinc finger protein GLI2 isoform X1 [KO:K16798]
100762738  Gli3; transcriptional activator GLI3 isoform X1 [KO:K06230]
100752564  Bmp2; bone morphogenetic protein 2 isoform X2 [KO:K21283]
100754303  Bmp4; bone morphogenetic protein 4 [KO:K04662]
100771283  Hhip; hedgehog-interacting protein [KO:K06231]
100753887  Ptch2; LOW QUALITY PROTEIN: protein patched homolog 2 isoform X2 [KO:K11101]
100752675  Ar; androgen receptor isoform X3 [KO:K08557]
100689397  Hsp90aa1; heat shock protein HSP 90-alpha [KO:K04079]
100773331  Hsp90b1; endoplasmin [KO:K09487]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
Reference
  Authors
Weinberg RA.
  Title
The biology of cancer
  Journal
Garland Science, Taylor & Francis Group, LLC (2007)
Reference
PMID:10647931
  Authors
Hanahan D, Weinberg RA
  Title
The hallmarks of cancer.
  Journal
Cell 100:57-70 (2000)
DOI:10.1016/S0092-8674(00)81683-9
Reference
PMID:15000146
  Authors
Grady WM.
  Title
Genomic instability and colon cancer.
  Journal
Cancer Metastasis Rev 23:11-27 (2004)
DOI:10.1023/A:1025861527711
Reference
PMID:16555243
  Authors
Soreide K, Janssen EA, Soiland H, Korner H, Baak JP.
  Title
Microsatellite instability in colorectal cancer.
  Journal
Br J Surg 93:395-406 (2006)
DOI:10.1002/bjs.5328
Reference
PMID:11078609
  Authors
Anwar S, Hall C, White J, Deakin M, Farrell W, Elder JB.
  Title
Hereditary non-polyposis colorectal cancer: an updated review.
  Journal
Eur J Surg Oncol 26:635-45 (2000)
DOI:10.1053/ejso.2000.0974
Reference
PMID:16699851
  Authors
Takayama T, Miyanishi K, Hayashi T, Sato Y, Niitsu Y.
  Title
Colorectal cancer: genetics of development and metastasis.
  Journal
J Gastroenterol 41:185-92 (2006)
DOI:10.1007/s00535-006-1801-6
Reference
PMID:12621137
  Authors
Lynch HT, de la Chapelle A.
  Title
Hereditary colorectal cancer.
  Journal
N Engl J Med 348:919-32 (2003)
DOI:10.1056/NEJMra012242
Reference
PMID:12951588
  Authors
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C.
  Title
The significance of unstable chromosomes in colorectal cancer.
  Journal
Nat Rev Cancer 3:695-701 (2003)
DOI:10.1038/nrc1165
Reference
PMID:10505543
  Authors
Behrens J.
  Title
Cadherins and catenins: role in signal transduction and tumor progression.
  Journal
Cancer Metastasis Rev 18:15-30 (1999)
DOI:10.1023/A:1006200102166
Reference
PMID:16042571
  Authors
Behrens J.
  Title
The role of the Wnt signalling pathway in colorectal tumorigenesis.
  Journal
Biochem Soc Trans 33:672-5 (2005)
DOI:10.1042/BST0330672
Reference
PMID:15349822
  Authors
Behrens J, Lustig B.
  Title
The Wnt connection to tumorigenesis.
  Journal
Int J Dev Biol 48:477-87 (2004)
DOI:10.1387/ijdb.041815jb
Reference
PMID:9196022
  Authors
Polakis P.
  Title
The adenomatous polyposis coli (APC) tumor suppressor.
  Journal
Biochim Biophys Acta 1332:F127-47 (1997)
DOI:10.1016/S0304-419X(97)00008-5
Reference
PMID:12737309
  Authors
Janssen KP.
  Title
Murine models of colorectal cancer: studying the role of oncogenic K-ras.
  Journal
Cell Mol Life Sci 60:495-506 (2003)
DOI:10.1007/s000180300041
Reference
PMID:11459867
  Authors
Adjei AA.
  Title
Blocking oncogenic Ras signaling for cancer therapy.
  Journal
J Natl Cancer Inst 93:1062-74 (2001)
DOI:10.1093/jnci/93.14.1062
Reference
PMID:15573119
  Authors
Arakawa H.
  Title
Netrin-1 and its receptors in tumorigenesis.
  Journal
Nat Rev Cancer 4:978-87 (2004)
DOI:10.1038/nrc1504
Reference
PMID:15310786
  Authors
Mehlen P, Fearon ER.
  Title
Role of the dependence receptor DCC in colorectal cancer pathogenesis.
  Journal
J Clin Oncol 22:3420-8 (2004)
DOI:10.1200/JCO.2004.02.019
Reference
PMID:11223406
  Authors
Peltomaki P.
  Title
DNA mismatch repair and cancer.
  Journal
Mutat Res 488:77-85 (2001)
DOI:10.1016/S1383-5742(00)00058-2
Reference
PMID:15711891
  Authors
Li F, Cao Y, Townsend CM Jr, Ko TC.
  Title
TGF-beta signaling in colon cancer cells.
  Journal
World J Surg 29:306-11 (2005)
DOI:10.1007/s00268-004-7813-6
Reference
PMID:11170304
  Authors
Roman C, Saha D, Beauchamp R.
  Title
TGF-beta and colorectal carcinogenesis.
  Journal
Microsc Res Tech 52:450-7 (2001)
DOI:10.1002/1097-0029(20010215)52:4<450::AID-JEMT1030>3.0.CO;2-O
Reference
PMID:16326109
  Authors
Watson AJ.
  Title
An overview of apoptosis and the prevention of colorectal cancer.
  Journal
Crit Rev Oncol Hematol 57:107-21 (2006)
DOI:10.1016/j.critrevonc.2005.06.005
Reference
PMID:15479695
  Authors
Watson AJ.
  Title
Apoptosis and colorectal cancer.
  Journal
Gut 53:1701-9 (2004)
DOI:10.1136/gut.2004.052704
Reference
PMID:11477132
  Authors
Houlston RS.
  Title
What we could do now: molecular pathology of colorectal cancer.
  Journal
Mol Pathol 54:206-14 (2001)
DOI:10.1136/mp.54.4.206
Reference
  Authors
Von Hoff D, Evans D, Hruban R (ed).
  Title
Pancreatic cancer
  Journal
Jones and Bartlett publishers (2005)
Reference
  Authors
Niitsu Y, Yokota J (ed).
  Title
[Oncogenes and Tumor Suppressor Genes for Medical Oncologist] (In Japanese)
  Journal
Nankodo (1999)
Reference
PMID:12459728
  Authors
Bardeesy N, DePinho RA.
  Title
Pancreatic cancer biology and genetics.
  Journal
Nat Rev Cancer 2:897-909 (2002)
DOI:10.1038/nrc949
Reference
PMID:11407945
  Authors
Bardeesy N, Sharpless NE, DePinho RA, Merlino G.
  Title
The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.
  Journal
Semin Cancer Biol 11:201-18 (2001)
DOI:10.1006/scbi.2000.0371
Reference
PMID:12946833
  Authors
Cowgill SM, Muscarella P.
  Title
The genetics of pancreatic cancer.
  Journal
Am J Surg 186:279-86 (2003)
DOI:10.1016/S0002-9610(03)00226-5
Reference
PMID:16702400
  Authors
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA.
  Title
Genetics and biology of pancreatic ductal adenocarcinoma.
  Journal
Genes Dev 20:1218-49 (2006)
DOI:10.1101/gad.1415606
Reference
PMID:10740269
  Authors
Shields JM, Pruitt K, McFall A, Shaub A, Der CJ.
  Title
Understanding Ras: 'it ain't over 'til it's over'.
  Journal
Trends Cell Biol 10:147-54 (2000)
DOI:10.1016/S0962-8924(00)01740-2
Reference
PMID:12648469
  Authors
Holbro T, Civenni G, Hynes NE.
  Title
The ErbB receptors and their role in cancer progression.
  Journal
Exp Cell Res 284:99-110 (2003)
DOI:10.1016/S0014-4827(02)00099-X
Reference
PMID:14967450
  Authors
Marmor MD, Skaria KB, Yarden Y.
  Title
Signal transduction and oncogenesis by ErbB/HER receptors.
  Journal
Int J Radiat Oncol Biol Phys 58:903-13 (2004)
DOI:10.1016/j.ijrobp.2003.06.002
Reference
PMID:14586404
  Authors
DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW.
  Title
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
  Journal
Oncogene 22:7781-95 (2003)
DOI:10.1038/sj.onc.1206966
Reference
PMID:12545153
  Authors
Wei D, Le X, Zheng L, Wang L, Frey JA, Gao AC, Peng Z, Huang S, Xiong HQ, Abbruzzese JL, Xie K.
  Title
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
  Journal
Oncogene 22:319-29 (2003)
DOI:10.1038/sj.onc.1206122
Reference
PMID:14580692
  Authors
Toyonaga T, Nakano K, Nagano M, Zhao G, Yamaguchi K, Kuroki S, Eguchi T, Chijiiwa K, Tsuneyoshi M, Tanaka M.
  Title
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
  Journal
Cancer Lett 201:107-16 (2003)
DOI:10.1016/S0304-3835(03)00482-8
Reference
PMID:12079267
  Authors
Schmid RM.
  Title
Genetic basis of pancreatic cancer.
  Journal
Best Pract Res Clin Gastroenterol 16:421-33 (2002)
DOI:10.1053/bega.2002.0316
Reference
PMID:15774796
  Authors
Elliott RL, Blobe GC.
  Title
Role of transforming growth factor Beta in human cancer.
  Journal
J Clin Oncol 23:2078-93 (2005)
DOI:10.1200/JCO.2005.02.047
Reference
PMID:15823750
  Authors
Rudkin TM, Foulkes WD.
  Title
BRCA2: breaks, mistakes and failed separations.
  Journal
Trends Mol Med 11:145-8 (2005)
DOI:10.1016/j.molmed.2005.02.003
Reference
PMID:11707511
  Authors
Venkitaraman AR.
  Title
Functions of BRCA1 and BRCA2 in the biological response to DNA damage.
  Journal
J Cell Sci 114:3591-8 (2001)
Reference
PMID:15639402
  Authors
Soni D, King JA, Kaye AH, Hovens CM.
  Title
Genetics of glioblastoma multiforme: mitogenic signaling and cell cycle pathways converge.
  Journal
J Clin Neurosci 12:1-5 (2005)
DOI:10.1016/j.jocn.2004.04.001
Reference
PMID:12154354
  Authors
Zhu Y, Parada LF.
  Title
The molecular and genetic basis of neurological tumours.
  Journal
Nat Rev Cancer 2:616-26 (2002)
DOI:10.1038/nrc866
Reference
PMID:11253051
  Authors
Holland EC.
  Title
Gliomagenesis: genetic alterations and mouse models.
  Journal
Nat Rev Genet 2:120-9 (2001)
DOI:10.1038/35052535
Reference
PMID:16700615
  Authors
Bansal K, Liang ML, Rutka JT.
  Title
Molecular biology of human gliomas.
  Journal
Technol Cancer Res Treat 5:185-94 (2006)
DOI:10.1177/153303460600500302
Reference
  Authors
Tabuchi K (ed).
  Title
[Gliomas: Research and therapy] (In Japanese)
  Journal
Springer-Verlag Tokyo (2006)
Reference
PMID:12762887
  Authors
Kapoor GS, O'Rourke DM.
  Title
Mitogenic signaling cascades in glial tumors.
  Journal
Neurosurgery 52:1425-34; discussion 1434-5 (2003)
DOI:10.1227/01.NEU.0000065135.28143.39
Reference
PMID:16095998
  Authors
Hulleman E, Helin K.
  Title
Molecular mechanisms in gliomagenesis.
  Journal
Adv Cancer Res 94:1-27 (2005)
DOI:10.1016/S0065-230X(05)94001-3
Reference
PMID:11057895
  Authors
Schlessinger J.
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 103:211-25 (2000)
DOI:10.1016/S0092-8674(00)00114-8
Reference
PMID:9643506
  Authors
Ng HK, Lam PY.
  Title
The molecular genetics of central nervous system tumors.
  Journal
Pathology 30:196-202 (1998)
DOI:10.1080/00313029800169236
Reference
PMID:12084351
  Authors
Knobbe CB, Merlo A, Reifenberger G.
  Title
Pten signaling in gliomas.
  Journal
Neuro-oncol 4:196-211 (2002)
DOI:10.1093/neuonc/4.3.196
Reference
PMID:16557281
  Authors
Kondo T, Ezzat S, Asa SL.
  Title
Pathogenetic mechanisms in thyroid follicular-cell neoplasia.
  Journal
Nat Rev Cancer 6:292-306 (2006)
DOI:10.1038/nrc1836
Reference
PMID:16551846
  Authors
Chiloeches A, Marais R.
  Title
Is BRAF the Achilles' Heel of thyroid cancer?
  Journal
Clin Cancer Res 12:1661-4 (2006)
DOI:10.1158/1078-0432.CCR-06-0051
Reference
PMID:16946003
  Authors
Reddi HV, McIver B, Grebe SK, Eberhardt NL
  Title
The paired box-8/peroxisome proliferator-activated receptor-gamma oncogene in thyroid tumorigenesis.
  Journal
Endocrinology 148:932-5 (2007)
DOI:10.1210/en.2006-0926
Reference
PMID:17062879
  Authors
Santoro M, Melillo RM, Fusco A.
  Title
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture.
  Journal
Eur J Endocrinol 155:645-653 (2006)
DOI:10.1530/eje.1.02289
Reference
PMID:16242838
  Authors
Pierotti MA, Greco A.
  Title
Oncogenic rearrangements of the NTRK1/NGF receptor.
  Journal
Cancer Lett 232:90-8 (2006)
DOI:10.1016/j.canlet.2005.07.043
Reference
PMID:16189702
  Authors
Sobrinho-Simoes M, Preto A, Rocha AS, Castro P, Maximo V, Fonseca E, Soares P.
  Title
Molecular pathology of well-differentiated thyroid carcinomas.
  Journal
Virchows Arch 447:787-93 (2005)
DOI:10.1007/s00428-005-0065-5
Reference
PMID:11165748
  Authors
Gimm O.
  Title
Thyroid cancer.
  Journal
Cancer Lett 163:143-56 (2001)
DOI:10.1016/S0304-3835(00)00697-2
Reference
PMID:12094241
  Authors
Williams D.
  Title
Cancer after nuclear fallout: lessons from the Chernobyl accident.
  Journal
Nat Rev Cancer 2:543-9 (2002)
DOI:10.1038/nrc845
Reference
PMID:16236521
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
PMID:12563308
  Authors
Tenen DG.
  Title
Disruption of differentiation in human cancer: AML shows the way.
  Journal
Nat Rev Cancer 3:89-101 (2003)
DOI:10.1038/nrc989
Reference
PMID:16146838
  Authors
Choudhary C, Muller-Tidow C, Berdel WE, Serve H.
  Title
Signal transduction of oncogenic Flt3.
  Journal
Int J Hematol 82:93-9 (2005)
DOI:10.1532/IJH97.05090
Reference
PMID:12951584
  Authors
Stirewalt DL, Radich JP.
  Title
The role of FLT3 in haematopoietic malignancies.
  Journal
Nat Rev Cancer 3:650-65 (2003)
DOI:10.1038/nrc1169
Reference
PMID:16642045
  Authors
Martelli AM, Nyakern M, Tabellini G, Bortul R, Tazzari PL, Evangelisti C, Cocco L.
  Title
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
  Journal
Leukemia 20:911-28 (2006)
DOI:10.1038/sj.leu.2404245
Reference
PMID:15625120
  Authors
Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R.
  Title
Normal and oncogenic forms of the receptor tyrosine kinase kit.
  Journal
Stem Cells 23:16-43 (2005)
DOI:10.1634/stemcells.2004-0117
Reference
PMID:11721960
  Authors
Lorsbach RB, Downing JR.
  Title
The role of the AML1 transcription factor in leukemogenesis.
  Journal
Int J Hematol 74:258-65 (2001)
DOI:10.1007/BF02982058
Reference
PMID:12468433
  Authors
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Bohmer FD, Muller-Tidow C, Berdel WE, Serve H.
  Title
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
  Journal
Blood 101:3164-73 (2003)
DOI:10.1182/blood-2002-06-1677
Reference
PMID:17554387
  Authors
Mikesch JH, Steffen B, Berdel WE, Serve H, Muller-Tidow C.
  Title
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
  Journal
Leukemia 21:1638-47 (2007)
DOI:10.1038/sj.leu.2404732
Reference
PMID:16352814
  Authors
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG.
  Title
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.
  Journal
Blood 107:3330-8 (2006)
DOI:10.1182/blood-2005-07-3068
Reference
PMID:15719031
  Authors
Ren R.
  Title
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia.
  Journal
Nat Rev Cancer 5:172-83 (2005)
DOI:10.1038/nrc1567
Reference
PMID:11071626
  Authors
Deininger MW, Goldman JM, Melo JV.
  Title
The molecular biology of chronic myeloid leukemia.
  Journal
Blood 96:3343-56 (2000)
Reference
PMID:14982876
  Authors
Calabretta B, Perrotti D.
  Title
The biology of CML blast crisis.
  Journal
Blood 103:4010-22 (2004)
DOI:10.1182/blood-2003-12-4111
Reference
PMID:10403855
  Authors
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM.
  Title
The biology of chronic myeloid leukemia.
  Journal
N Engl J Med 341:164-72 (1999)
DOI:10.1056/NEJM199907153410306
Reference
PMID:15156182
  Authors
Mitani K.
  Title
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
  Journal
Oncogene 23:4263-9 (2004)
DOI:10.1038/sj.onc.1207777
Reference
PMID:16484590
  Authors
Dong M, Blobe GC.
  Title
Role of transforming growth factor-beta in hematologic malignancies.
  Journal
Blood 107:4589-96 (2006)
DOI:10.1182/blood-2005-10-4169
Reference
PMID:9834202
  Authors
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H.
  Title
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
  Journal
Blood 92:4003-12 (1998)
Reference
PMID:12801837
  Authors
Brusa G, Benvenuti M, Mazzacurati L, Mancini M, Pattacini L, Martinelli G, Barbieri E, Greenberger JS, Baccarani M, Santucci MA.
  Title
p53 loss of function enhances genomic instability and accelerates clonal evolution of murine myeloid progenitors expressing the p(210)BCR-ABL tyrosine kinase.
  Journal
Haematologica 88:622-30 (2003)
Reference
PMID:11160144
  Authors
Baldwin AS.
  Title
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.
  Journal
J Clin Invest 107:241-6 (2001)
DOI:10.1172/JCI11991
Reference
PMID:12244301
  Authors
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.
  Title
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
  Journal
Nat Med 8:1145-52 (2002)
DOI:10.1038/nm759
Reference
PMID:15948971
  Authors
Tilli CM, Van Steensel MA, Krekels GA, Neumann HA, Ramaekers FC.
  Title
Molecular aetiology and pathogenesis of basal cell carcinoma.
  Journal
Br J Dermatol 152:1108-24 (2005)
DOI:10.1111/j.1365-2133.2005.06587.x
Reference
PMID:12588368
  Authors
Saldanha G, Fletcher A, Slater DN.
  Title
Basal cell carcinoma: a dermatopathological and molecular biological update.
  Journal
Br J Dermatol 148:195-202 (2003)
DOI:10.1046/j.1365-2133.2003.05151.x
Reference
PMID:15978322
  Authors
Daya-Grosjean L, Couve-Privat S.
  Title
Sonic hedgehog signaling in basal cell carcinomas.
  Journal
Cancer Lett 225:181-92 (2005)
DOI:10.1016/j.canlet.2004.10.003
Reference
PMID:15468170
  Authors
Tsai KY, Tsao H.
  Title
The genetics of skin cancer.
  Journal
Am J Med Genet C Semin Med Genet 131C:82-92 (2004)
DOI:10.1002/ajmg.c.30037
Reference
PMID:16881963
  Authors
Athar M, Tang X, Lee JL, Kopelovich L, Kim AL.
  Title
Hedgehog signalling in skin development and cancer.
  Journal
Exp Dermatol 15:667-77 (2006)
DOI:10.1111/j.1600-0625.2006.00473.x
Reference
PMID:16306523
  Authors
Rubin AI, Chen EH, Ratner D.
  Title
Basal-cell carcinoma.
  Journal
N Engl J Med 353:2262-9 (2005)
DOI:10.1056/NEJMra044151
Reference
PMID:11276000
  Authors
Saldanha G.
  Title
The Hedgehog signalling pathway and cancer.
  Journal
J Pathol 193:427-32 (2001)
DOI:10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N
Reference
PMID:15270885
  Authors
Saldanha G, Ghura V, Potter L, Fletcher A.
  Title
Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation.
  Journal
Br J Dermatol 151:157-64 (2004)
DOI:10.1111/j.1365-2133.2004.06048.x
Reference
PMID:14737121
  Authors
Pasca di Magliano M, Hebrok M.
  Title
Hedgehog signalling in cancer formation and maintenance.
  Journal
Nat Rev Cancer 3:903-11 (2003)
DOI:10.1038/nrc1229
Reference
PMID:15656799
  Authors
Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G.
  Title
Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas.
  Journal
Br J Dermatol 152:43-51 (2005)
DOI:10.1111/j.1365-2133.2005.06353.x
Reference
PMID:14556242
  Authors
Cohen MM Jr.
  Title
The hedgehog signaling network.
  Journal
Am J Med Genet A 123:5-28 (2003)
DOI:10.1002/ajmg.a.20495
Reference
PMID:11736900
  Authors
Yamazaki F, Aragane Y, Kawada A, Tezuka T.
  Title
Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma.
  Journal
Br J Dermatol 145:771-7 (2001)
DOI:10.1046/j.1365-2133.2001.04468.x
Reference
PMID:16054233
  Authors
Erb P, Ji J, Wernli M, Kump E, Glaser A, Buchner SA.
  Title
Role of apoptosis in basal cell and squamous cell carcinoma formation.
  Journal
Immunol Lett 100:68-72 (2005)
DOI:10.1016/j.imlet.2005.06.008
Reference
PMID:11130178
  Authors
Toftgard R.
  Title
Hedgehog signalling in cancer.
  Journal
Cell Mol Life Sci 57:1720-31 (2000)
DOI:10.1007/PL00000654
Reference
PMID:16822996
  Authors
Miller AJ, Mihm MC Jr.
  Title
Melanoma.
  Journal
N Engl J Med 355:51-65 (2006)
DOI:10.1056/NEJMra052166
Reference
PMID:12894244
  Authors
Chin L.
  Title
The genetics of malignant melanoma: lessons from mouse and man.
  Journal
Nat Rev Cancer 3:559-70 (2003)
DOI:10.1038/nrc1145
Reference
PMID:16750612
  Authors
Takata M, Saida T.
  Title
Genetic alterations in melanocytic tumors.
  Journal
J Dermatol Sci 43:1-10 (2006)
DOI:10.1016/j.jdermsci.2006.05.002
Reference
PMID:15841168
  Authors
Chudnovsky Y, Khavari PA, Adams AE.
  Title
Melanoma genetics and the development of rational therapeutics.
  Journal
J Clin Invest 115:813-24 (2005)
DOI:10.1172/JCI24808
Reference
PMID:16001050
  Authors
Merlino G.
  Title
Cancer biology: the weakest link?
  Journal
Nature 436:33-5 (2005)
DOI:10.1038/436033a
Reference
PMID:16001072
  Authors
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR.
  Title
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
  Journal
Nature 436:117-22 (2005)
DOI:10.1038/nature03664
Reference
PMID:16899407
  Authors
Levy C, Khaled M, Fisher DE.
  Title
MITF: master regulator of melanocyte development and melanoma oncogene.
  Journal
Trends Mol Med 12:406-14 (2006)
DOI:10.1016/j.molmed.2006.07.008
Reference
PMID:15009714
  Authors
Tsao H, Goel V, Wu H, Yang G, Haluska FG.
  Title
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.
  Journal
J Invest Dermatol 122:337-41 (2004)
DOI:10.1046/j.0022-202X.2004.22243.x
Reference
PMID:11224709
  Authors
Gruss C, Herlyn M.
  Title
Role of cadherins and matrixins in melanoma.
  Journal
Curr Opin Oncol 13:117-23 (2001)
DOI:10.1097/00001622-200103000-00006
Reference
PMID:15721476
  Authors
Thompson JF, Scolyer RA, Kefford RF.
  Title
Cutaneous melanoma.
  Journal
Lancet 365:687-701 (2005)
DOI:10.1016/S0140-6736(05)17951-3
Reference
PMID:14695152
  Authors
Omholt K, Platz A, Kanter L, Ringborg U, Hansson J.
  Title
NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.
  Journal
Clin Cancer Res 9:6483-8 (2003)
Reference
PMID:15557758
  Authors
Hussein MR.
  Title
The TP53 tumor suppressor gene and melanoma tumorigenesis: is there a relationship?
  Journal
Tumour Biol 25:200-7 (2004)
DOI:10.1159/000081103
Reference
PMID:10843728
  Authors
Lazar-Molnar E, Hegyesi H, Toth S, Falus A.
  Title
Autocrine and paracrine regulation by cytokines and growth factors in melanoma.
  Journal
Cytokine 12:547-54 (2000)
DOI:10.1006/cyto.1999.0614
Reference
PMID:16339096
  Authors
Cohen HT, McGovern FJ.
  Title
Renal-cell carcinoma.
  Journal
N Engl J Med 353:2477-90 (2005)
DOI:10.1056/NEJMra043172
Reference
PMID:15122209
  Authors
Pavlovich CP, Schmidt LS.
  Title
Searching for the hereditary causes of renal-cell carcinoma.
  Journal
Nat Rev Cancer 4:381-93 (2004)
DOI:10.1038/nrc1364
Reference
PMID:14634372
  Authors
Linehan WM, Walther MM, Zbar B.
  Title
The genetic basis of cancer of the kidney.
  Journal
J Urol 170:2163-72 (2003)
DOI:10.1097/01.ju.0000096060.92397.ed
Reference
PMID:14685170
  Authors
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF.
  Title
Met, metastasis, motility and more.
  Journal
Nat Rev Mol Cell Biol 4:915-25 (2003)
DOI:10.1038/nrm1261
Reference
PMID:15611513
  Authors
Kim WY, Kaelin WG.
  Title
Role of VHL gene mutation in human cancer.
  Journal
J Clin Oncol 22:4991-5004 (2004)
DOI:10.1200/JCO.2004.05.061
Reference
PMID:17211469
  Authors
Sudarshan S, Linehan WM, Neckers L.
  Title
HIF and fumarate hydratase in renal cancer.
  Journal
Br J Cancer 96:403-7 (2007)
DOI:10.1038/sj.bjc.6603547
Reference
PMID:17287871
  Authors
Sudarshan S, Pinto PA, Neckers L, Linehan WM.
  Title
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer.
  Journal
Nat Clin Pract Urol 4:104-10 (2007)
DOI:10.1038/ncpuro0711
Reference
PMID:12351585
  Authors
Bodmer D, van den Hurk W, van Groningen JJ, Eleveld MJ, Martens GJ, Weterman MA, van Kessel AG.
  Title
Understanding familial and non-familial renal cell cancer.
  Journal
Hum Mol Genet 11:2489-98 (2002)
DOI:10.1093/hmg/11.20.2489
Reference
PMID:17158541
  Authors
Mitra AP, Datar RH, Cote RJ.
  Title
Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification.
  Journal
J Clin Oncol 24:5552-64 (2006)
DOI:10.1200/JCO.2006.08.2073
Reference
PMID:16474624
  Authors
Wolff EM, Liang G, Jones PA.
  Title
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer.
  Journal
Nat Clin Pract Urol 2:502-10 (2005)
DOI:10.1038/ncpuro0318
Reference
PMID:16110317
  Authors
Wu XR.
  Title
Urothelial tumorigenesis: a tale of divergent pathways.
  Journal
Nat Rev Cancer 5:713-25 (2005)
DOI:10.1038/nrc1697
Reference
PMID:11103787
  Authors
Brown NS, Jones A, Fujiyama C, Harris AL, Bicknell R.
  Title
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
  Journal
Cancer Res 60:6298-302 (2000)
Reference
PMID:12850530
  Authors
Bellmunt J, Hussain M, Dinney CP.
  Title
Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family.
  Journal
Crit Rev Oncol Hematol 46 Suppl:S85-104 (2003)
DOI:10.1016/S1040-8428(03)00067-2
Reference
PMID:17149381
  Authors
Sugano K, Kakizoe T.
  Title
Genetic alterations in bladder cancer and their clinical applications in molecular tumor staging.
  Journal
Nat Clin Pract Urol 3:642-52 (2006)
DOI:10.1038/ncpuro0649
Reference
PMID:15746962
  Authors
Dunn KL, Espino PS, Drobic B, He S, Davie JR.
  Title
The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.
  Journal
Biochem Cell Biol 83:1-14 (2005)
DOI:10.1139/o04-121
Reference
PMID:15551095
  Authors
Williams SG, Stein JP.
  Title
Molecular pathways in bladder cancer.
  Journal
Urol Res 32:373-85 (2004)
DOI:10.1007/s00240-003-0345-y
Reference
PMID:12878745
  Authors
Nelson WG, De Marzo AM, Isaacs WB.
  Title
Prostate cancer.
  Journal
N Engl J Med 349:366-81 (2003)
DOI:10.1056/NEJMra021562
Reference
PMID:15724144
  Authors
Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC.
  Title
The emerging role of the PI3-K-Akt pathway in prostate cancer progression.
  Journal
Prostate Cancer Prostatic Dis 8:108-18 (2005)
DOI:10.1038/sj.pcan.4500776
Reference
PMID:16551847
  Authors
Pienta KJ, Bradley D.
  Title
Mechanisms underlying the development of androgen-independent prostate cancer.
  Journal
Clin Cancer Res 12:1665-71 (2006)
DOI:10.1158/1078-0432.CCR-06-0067
Reference
PMID:11900250
  Authors
Feldman BJ, Feldman D.
  Title
The development of androgen-independent prostate cancer.
  Journal
Nat Rev Cancer 1:34-45 (2001)
DOI:10.1038/35094009
Reference
PMID:15082523
  Authors
Heinlein CA, Chang C.
  Title
Androgen receptor in prostate cancer.
  Journal
Endocr Rev 25:276-308 (2004)
DOI:10.1210/er.2002-0032
Reference
PMID:9422516
  Authors
Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP.
  Title
Androgen receptor gene and hormonal therapy failure of prostate cancer.
  Journal
Am J Pathol 152:1-9 (1998)
Reference
PMID:10835690
  Authors
Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, Feldman D.
  Title
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor.
  Journal
Nat Med 6:703-6 (2000)
DOI:10.1038/76287
Reference
PMID:10453277
  Authors
Macri E, Loda M.
  Title
Role of p27 in prostate carcinogenesis.
  Journal
Cancer Metastasis Rev 17:337-44 (1998)
DOI:10.1023/A:1006133620914
Reference
PMID:11750244
  Authors
Steers WD.
  Title
5alpha-reductase activity in the prostate.
  Journal
Urology 58:17-24; discussion 24 (2001)
DOI:10.1016/S0090-4295(01)01299-7
Reference
PMID:8069858
  Authors
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF.
  Title
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
  Journal
Cancer Res 54:4920-6 (1994)
Reference
PMID:11527574
  Authors
Grimes CA, Jope RS.
  Title
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
  Journal
Prog Neurobiol 65:391-426 (2001)
DOI:10.1016/S0301-0082(01)00011-9
Reference
PMID:15947972
  Authors
Ryan AJ, Susil B, Jobling TW, Oehler MK.
  Title
Endometrial cancer.
  Journal
Cell Tissue Res 322:53-61 (2005)
DOI:10.1007/s00441-005-1109-5
Reference
PMID:14747944
  Authors
Lax SF.
  Title
Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification.
  Journal
Virchows Arch 444:213-23 (2004)
DOI:10.1007/s00428-003-0947-3
Reference
PMID:16508724
  Authors
Shiozawa T, Konishi I.
  Title
Early endometrial carcinoma: clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment.
  Journal
Int J Clin Oncol 11:13-21 (2006)
DOI:10.1007/s10147-005-0546-1
Reference
PMID:17028294
  Authors
Hecht JL, Mutter GL.
  Title
Molecular and pathologic aspects of endometrial carcinogenesis.
  Journal
J Clin Oncol 24:4783-91 (2006)
DOI:10.1200/JCO.2006.06.7173
Reference
PMID:11431710
  Authors
Matias-Guiu X, Catasus L, Bussaglia E, Lagarda H, Garcia A, Pons C, Munoz J, Arguelles R, Machin P, Prat J.
  Title
Molecular pathology of endometrial hyperplasia and carcinoma.
  Journal
Hum Pathol 32:569-77 (2001)
DOI:10.1053/hupa.2001.25929
Reference
PMID:15284264
  Authors
Slomovitz BM, Broaddus RR, Burke TW, Sneige N, Soliman PT, Wu W, Sun CC, Munsell MF, Gershenson DM, Lu KH.
  Title
Her-2/neu overexpression and amplification in uterine papillary serous carcinoma.
  Journal
J Clin Oncol 22:3126-32 (2004)
DOI:10.1200/JCO.2004.11.154
Reference
PMID:7585656
  Authors
Saffari B, Jones LA, el-Naggar A, Felix JC, George J, Press MF.
  Title
Amplification and overexpression of HER-2/neu (c-erbB2) in endometrial cancers: correlation with overall survival.
  Journal
Cancer Res 55:5693-8 (1995)
Reference
PMID:16248975
  Authors
Kim D, Chung J.
  Title
Akt: versatile mediator of cell survival and beyond.
  Journal
J Biochem Mol Biol 35:106-15 (2002)
DOI:10.5483/bmbrep.2002.35.1.106
Reference
PMID:12711111
  Authors
Sanchez-Cespedes M.
  Title
Dissecting the genetic alterations involved in lung carcinogenesis.
  Journal
Lung Cancer 40:111-21 (2003)
DOI:10.1016/S0169-5002(03)00033-3
Reference
PMID:11720739
  Authors
Kaye FJ.
  Title
Molecular biology of lung cancer.
  Journal
Lung Cancer 34 Suppl 2:S35-41 (2001)
DOI:10.1016/S0169-5002(01)00342-7
Reference
PMID:12616528
  Authors
Shivapurkar N, Reddy J, Chaudhary PM, Gazdar AF.
  Title
Apoptosis and lung cancer: a review.
  Journal
J Cell Biochem 88:885-98 (2003)
DOI:10.1002/jcb.10440
Reference
PMID:11807782
  Authors
Sartorius UA, Krammer PH.
  Title
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
  Journal
Int J Cancer 97:584-92 (2002)
DOI:10.1002/ijc.10096
Reference
PMID:16064138
  Authors
Adhikary S, Eilers M.
  Title
Transcriptional regulation and transformation by Myc proteins.
  Journal
Nat Rev Mol Cell Biol 6:635-45 (2005)
DOI:10.1038/nrm1703
Reference
PMID:11463388
  Authors
Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI.
  Title
A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
  Journal
Mol Cell 7:639-50 (2001)
DOI:10.1016/S1097-2765(01)00210-6
Reference
PMID:15109562
  Authors
Buttery RC, Rintoul RC, Sethi T.
  Title
Small cell lung cancer: the importance of the extracellular matrix.
  Journal
Int J Biochem Cell Biol 36:1154-60 (2004)
DOI:10.1016/S1357-2725(03)00261-9
Reference
PMID:11559746
  Authors
Yamada KM, Araki M.
  Title
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis.
  Journal
J Cell Sci 114:2375-82 (2001)
Reference
PMID:11905738
  Authors
Rintoul RC, Sethi T.
  Title
The role of extracellular matrix in small-cell lung cancer.
  Journal
Lancet Oncol 2:437-42 (2001)
DOI:10.1016/S1470-2045(00)00421-6
Reference
PMID:12243753
  Authors
Ekedahl J, Joseph B, Grigoriev MY, Muller M, Magnusson C, Lewensohn R, Zhivotovsky B.
  Title
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.
  Journal
Exp Cell Res 279:277-90 (2002)
DOI:10.1006/excr.2002.5608
Reference
PMID:12379883
  Authors
Osada H, Takahashi T.
  Title
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.
  Journal
Oncogene 21:7421-34 (2002)
DOI:10.1038/sj.onc.1205802
Reference
PMID:12741677
  Authors
Yokota J, Nishioka M, Tani M, Kohno T.
  Title
Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
  Journal
Clin Exp Metastasis 20:189-93 (2003)
DOI:10.1023/a:1022978932215
Reference
PMID:16870043
  Authors
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS.
  Title
K-ras mutations in non-small-cell lung carcinoma: a review.
  Journal
Clin Lung Cancer 8:30-8 (2006)
DOI:10.3816/CLC.2006.n.030
Reference
PMID:15948711
  Authors
Pfeifer GP, Dammann R.
  Title
Methylation of the tumor suppressor gene RASSF1A in human tumors.
  Journal
Biochemistry (Mosc) 70:576-83 (2005)
DOI:10.1007/s10541-005-0151-y
Reference
PMID:11902573
  Authors
Altucci L, Gronemeyer H.
  Title
The promise of retinoids to fight against cancer.
  Journal
Nat Rev Cancer 1:181-93 (2001)
DOI:10.1038/35106036
Reference
PMID:10944551
  Authors
Virmani AK, Rathi A, Zochbauer-Muller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF.
  Title
Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.
  Journal
J Natl Cancer Inst 92:1303-7 (2000)
DOI:10.1093/jnci/92.16.1303
Reference
PMID:12867060
  Authors
Hirsch FR, Scagliotti GV, Langer CJ, Varella-Garcia M, Franklin WA.
  Title
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies.
  Journal
Lung Cancer 41 Suppl 1:S29-42 (2003)
DOI:10.1016/S0169-5002(03)00137-5
Reference
PMID:16112428
  Authors
Panani AD, Roussos C.
  Title
Cytogenetic and molecular aspects of lung cancer.
  Journal
Cancer Lett 239:1-9 (2006)
DOI:10.1016/j.canlet.2005.06.030
Reference
PMID:12407699
  Authors
Mitsuuchi Y, Testa JR.
  Title
Cytogenetics and molecular genetics of lung cancer.
  Journal
Am J Med Genet 115:183-8 (2002)
DOI:10.1002/ajmg.10692
Reference
PMID:15942304
  Authors
Breuer RH, Postmus PE, Smit EF.
  Title
Molecular pathology of non-small-cell lung cancer.
  Journal
Respiration 72:313-30 (2005)
DOI:10.1159/000085376
Reference
PMID:11895903
  Authors
Piyathilake CJ, Frost AR, Manne U, Weiss H, Bell WC, Heimburger DC, Grizzle WE.
  Title
Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.
  Journal
Clin Cancer Res 8:734-44 (2002)
Reference
PMID:16189154
  Authors
Awaya H, Takeshima Y, Furonaka O, Kohno N, Inai K.
  Title
Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung.
  Journal
J Clin Pathol 58:1076-80 (2005)
DOI:10.1136/jcp.2004.025585
Reference
PMID:21193867
  Authors
Lappano R, Maggiolini M
  Title
G protein-coupled receptors: novel targets for drug discovery in cancer.
  Journal
Nat Rev Drug Discov 10:47-60 (2011)
DOI:10.1038/nrd3320
Reference
PMID:24508914
  Authors
O'Hayre M, Degese MS, Gutkind JS
  Title
Novel insights into G protein and G protein-coupled receptor signaling in cancer.
  Journal
Curr Opin Cell Biol 27:126-35 (2014)
DOI:10.1016/j.ceb.2014.01.005
Reference
PMID:17251915
  Authors
Dorsam RT, Gutkind JS
  Title
G-protein-coupled receptors and cancer.
  Journal
Nat Rev Cancer 7:79-94 (2007)
DOI:10.1038/nrc2069
Related
pathway
cge03320  PPAR signaling pathway
cge04010  MAPK signaling pathway
cge04020  Calcium signaling pathway
cge04024  cAMP signaling pathway
cge04060  Cytokine-cytokine receptor interaction
cge04066  HIF-1 signaling pathway
cge04110  Cell cycle
cge04115  p53 signaling pathway
cge04150  mTOR signaling pathway
cge04151  PI3K-Akt signaling pathway
cge04210  Apoptosis
cge04310  Wnt signaling pathway
cge04330  Notch signaling pathway
cge04340  Hedgehog signaling pathway
cge04350  TGF-beta signaling pathway
cge04370  VEGF signaling pathway
cge04510  Focal adhesion
cge04512  ECM-receptor interaction
cge04520  Adherens junction
cge04630  JAK-STAT signaling pathway
cge04915  Estrogen signaling pathway
KO pathway
ko05200   
LinkDB

DBGET integrated database retrieval system