KEGG   PATHWAY: acat04070
Entry
acat04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Aquarana catesbeiana (American bullfrog)
Class
Environmental Information Processing; Signal transduction
Pathway map
acat04070  Phosphatidylinositol signaling system
acat04070

Organism
Aquarana catesbeiana (American bullfrog) [GN:acat]
Gene
141102426  [KO:K04958]
141102610  [KO:K04958]
141102730  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
141102813  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
141102885  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
141102941  MTMR14; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
141103269  IPPK; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
141103897  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
141104680  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
141105584  PI4K2A; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
141105675  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
141105715  INPP5F; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
141106008  IPMK; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
141106014  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
141106052  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
141107427  OCRL; inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
141107653  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
141107786  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
141108064  MTM1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
141108065  MTMR1; phosphatidylinositol-3-phosphate phosphatase MTMR1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
141108157  MTMR8; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
141108210  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
141108231  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
141108534  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
141108824  [KO:K15909] [EC:3.1.3.86]
141110828  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
141110934  PRKCG; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
141111334  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
141111990  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
141111997  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
141112486  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
141112825  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
141113325  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
141113498  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
141114191  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
141114265  [KO:K02677] [EC:2.7.11.13]
141114419  MTMR7; phosphatidylinositol-3-phosphate phosphatase MTMR7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
141114527  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
141116406  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
141116415  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
141116440  CALM1; calmodulin-1 [KO:K02183]
141116733  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
141117087  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
141117231  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
141126675  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
141126955  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
141126957  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
141126959  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
141127187  MTMR6; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
141127396  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
141127467  DGKA; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
141127594  DGKH; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
141127836  INPP4A; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
141128302  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
141128507  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
141128638  ITPR3; inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 isoform X1 [KO:K04960]
141128906  MTMR4; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
141129233  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
141131218  CALML4; calmodulin-like protein 4 [KO:K02183]
141131369  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
141131446  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
141132681  PIK3C2G; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
141132835  ITPR2; inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 isoform X1 [KO:K04959]
141132877  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
141132987  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
141133751  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
141133993  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
141137309  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 [KO:K13024] [EC:2.7.4.24]
141139514  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
141139525  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
141139587  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
141139779  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
141140564  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
141140798  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
141140949  [KO:K02183]
141140950  [KO:K02183]
141141001  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
141141002  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
141141461  PI4KA; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
141144060  [KO:K01116] [EC:3.1.4.11]
141144129  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
141144264  [KO:K00920] [EC:2.7.1.149]
141144388  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [KO:K05857] [EC:3.1.4.11]
141144719  SACM1L; phosphatidylinositol-3-phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
141144767  MTMR3; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
141145048  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
141145078  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
141145190  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
141145300  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
141145346  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
141146708  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
141146810  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
141147210  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
141147509  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
141148472  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
141148777  PRKCB; protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
acat04020  Calcium signaling pathway
acat04144  Endocytosis
acat04510  Focal adhesion
KO pathway
ko04070   

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