KEGG   PATHWAY: gvr04070
Entry
gvr04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Galeopterus variegatus (Sunda flying lemur)
Class
Environmental Information Processing; Signal transduction
Pathway map
gvr04070  Phosphatidylinositol signaling system
gvr04070

Organism
Galeopterus variegatus (Sunda flying lemur) [GN:gvr]
Gene
103582776  [KO:K13711] [EC:2.7.1.67]
103583388  [KO:K19663] [EC:2.7.11.13]
103584934  IP6K2; inositol hexakisphosphate kinase 2 isoform X1 [KO:K07756] [EC:2.7.4.21]
103585463  PIK3R3; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
103585872  INPPL1; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
103586228  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
103586572  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
103586784  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103587678  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
103587883  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
103587958  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
103588449  CALM1; calmodulin [KO:K02183]
103588545  [KO:K05858] [EC:3.1.4.11]
103588715  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
103588744  MTMR7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
103588915  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
103589318  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
103589381  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
103589409  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
103589546  IP6K1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
103589793  MTMR6; LOW QUALITY PROTEIN: myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
103590206  OCRL; inositol polyphosphate 5-phosphatase OCRL-1 [KO:K01099] [EC:3.1.3.36]
103590868  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
103590899  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
103590941  PIK3C2A; LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
103591300  [KO:K05858] [EC:3.1.4.11]
103591330  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
103591510  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
103591521  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
103592574  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
103592918  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
103592983  CALM3; LOW QUALITY PROTEIN: calmodulin [KO:K02183]
103593465  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
103593683  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
103594028  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
103594173  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
103594206  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
103594270  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
103594536  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
103594586  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
103594813  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
103595744  SACM1L; phosphatidylinositide phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
103595841  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
103595999  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
103596484  PLCB1; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
103596511  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
103596896  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
103596943  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
103597026  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
103597061  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
103597370  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
103597696  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
103597698  [KO:K04960]
103598056  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
103598175  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
103598547  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
103598637  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
103598708  [KO:K00923] [EC:2.7.1.154]
103598843  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [KO:K00889] [EC:2.7.1.68]
103599056  [KO:K00901] [EC:2.7.1.107]
103599063  [KO:K01106] [EC:3.1.3.56]
103599152  INPP4B; type II inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
103599242  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
103599299  MTMR2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
103599363  TMEM55A; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
103599423  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
103599593  [KO:K00921] [EC:2.7.1.150]
103599669  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
103599723  CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
103599847  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
103599899  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
103600026  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
103600304  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
103601309  [KO:K02183]
103601310  CALML5; calmodulin-like protein 5 [KO:K02183]
103601992  [KO:K02183]
103602095  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
103602368  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
103602607  SYNJ2; synaptojanin-2 [KO:K20279] [EC:3.1.3.36]
103603108  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
103603506  PI4KA; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
103603552  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
103603652  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
103603782  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
103603924  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
103604023  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
103604050  IMPAD1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
103604693  MTM1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
103605041  TMEM55B; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
103605556  [KO:K00923] [EC:2.7.1.154]
103605571  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
103605799  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
103606081  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
103606318  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
103606378  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [KO:K05858] [EC:3.1.4.11]
103608454  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
103608788  DGKK; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
103609321  [KO:K01107] [EC:3.1.3.57]
103610795  [KO:K00901] [EC:2.7.1.107]
103610819  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
gvr04020  Calcium signaling pathway
gvr04144  Endocytosis
gvr04151  PI3K-Akt signaling pathway
gvr04510  Focal adhesion
KO pathway
ko04070   

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